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7261
Pulmonary hypertension in ischemic heart failure: a pilot study
Published 2024-09-01“…The patients included in the study were mainly men (73,8%), functional class PH II-III (95,2%), stage IIB CHF (62%). …”
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7262
The relationship between self-determination and personal choice of participation in extreme volunteerism
Published 2025-05-01“…The orientation of the choice of participation in the diagnosed continuum “ideality — materiality” depends on the formation of functional and semantic self-determination as components of a complementary model, self-awareness, ideality, prosocial value orientation, motivation, propensity and activity in extreme activities, critical thinking. …”
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7263
ZEB1 transcription factor promotes immune escape in melanoma
Published 2022-03-01“…Algorithm-based spatial reconstitution of tumors allowed the quantification of CD8+, CD4+ T cells number and their activation state (PD-1, Ki67). ZEB1 gain-of-function or loss-of-function approaches were then implemented in syngeneic melanoma mouse models, followed by monitoring of tumor growth, quantification of immune cell populations frequency and function by flow cytometry, cytokines secretion by multiplex analyses. …”
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7264
Cryo-EM structures of a protein pore reveal a cluster of cholesterol molecules and diverse roles of membrane lipids
Published 2025-03-01“…Abstract The structure and function of membrane proteins depend on their interactions with lipids that constitute membranes. …”
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7265
The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer
Published 2024-11-01“…We have conducted a meticulous analysis of the function of this tsRNA. NOTCH1 was conducive to cancer-associated fibroblasts (CAFs) immune infiltration, while the metastatic process was more dependent on the differentiation and angiogenesis function of NOTCH1. …”
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7266
Human Resource Management Between Economy and Ethics – Research of Serbia and Bosnia and Hercegovina
Published 2020-09-01“…In elaborating this problem, we started from the basic assumption that human resource management as an organizational function and theoretical concept should balance between economic and ethical requirements, which depends on the attitudes of managers as decision makers. …”
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7267
Research of influencing constructive parameters of an autoGrader’s operating device on its performance
Published 2017-08-01“…There are identified functional dependencies of a criterion of maximizing operational performance of the autograder. …”
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7268
Robust Stability of Neutral System with Mixed Time-Varying Delays and Nonlinear Perturbations Using Delay Decomposition Approach
Published 2014-01-01“…Then, based on a special Lyapunov functional approach, the novel delay-dependent stability criteria are obtained in terms of linear matrix inequalities (LMIs). …”
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7269
Bivariate Chebyshev Type Inequalities for Alpha Diamond Integrals via Time Scale Calculus
Published 2025-01-01“…In this article, some generalizations of inequalities involving Chebyshev functional depending upon two parameters, for the class of twice differentiable functions on time scales, are studied. …”
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7270
AREG+ regulatory T cells mediating myocardial repair and neovascularization after myocardial infarction
Published 2025-06-01“…Abstract Enhancing tissue repair and angiogenesis post-Acute myocardial infarction (AMI) is critical to improving cardiac function and preventing heart failure. Recent studies have highlighted the interaction between immune cells and endothelial cells in post-AMI angiogenesis, yet the specific contributions of different immune cell subsets remain poorly understood. …”
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7271
Dread and the disvalue of future pain.
Published 2013-01-01“…Framing an outcome as relief reduces the overall preference to expedite pain, which can be parameterized by reducing the rate of the dread-discounting function. Our data support an account of disvaluation for primary punishments such as pain, which differs fundamentally from existing models applied to financial punishments, in which dread exerts a powerful but time-dependent influence over choice.…”
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7272
Optimal Pricing Decision of Fashion Apparel considering Experiential Service and Design Enhancement
Published 2020-01-01“…First, a Cobb–Douglas utility function is used to derive a demand function that depends on the price and fashion level. …”
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7273
Assessment of Arterial Stiffness Using the Cardio-Ankle Vascular Index – What We Know and What We Strive for
Published 2021-09-01“…The use of CAVI also opens up new perspectives in the assessment of cardiovascular interactions, the study of vascular function in vasculitis and vascular injuries, as well as in geriatric medicine (concepts of premature vascular aging and excess vascular aging).…”
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7274
RES complex is associated with intron definition and required for zebrafish early embryogenesis.
Published 2018-07-01“…Using these features, we developed and validated a predictive model that classifies RES dependent introns. Altogether, our study uncovers the essential role of the RES complex during vertebrate development and provides new insights into its function during splicing.…”
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7275
Exploring feature sparsity for out-of-distribution detection
Published 2024-11-01“…One key drawback, however, is that the loss function parameters are highly dependent on involved datasets, which means it cannot be dynamically adapted and implemented in others settings; in other words, the general ability of the energy score is considerably limited. …”
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7276
Metatheoretical Foundations of Educational Theory. Selected Aspects
Published 2024-10-01“…Their subject is educational theory, while the aim is to formulate descriptive metatheoretical remarks on selected aspects of the functioning of educational theory as a sub-discipline of pedagogical science. …”
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7277
Mitochondrial Dysfunction and Metabolic Disturbances Induced by Viral Infections
Published 2024-10-01“…We also describe how viruses directly regulate mitochondrial function through modulation of the activity of the electron transport chain, the generation of reactive oxygen species, the balance between fission and fusion, and the regulation of voltage-dependent anion channels. …”
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7278
Benchmarking of bioinformatics tools for the hybrid de novo assembly of human and non-human whole-genome sequencing data
Published 2025-01-01“…Accurate and complete de novo genome assemblies enable variant identification and the discovery of novel genomic features and biological functions. However, de novo assemblies of large and complex genomes remain challenging. …”
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7279
Efficacy and mechanism of long-snake moxibustion for treating insomnia in breast cancer survivors: study protocol for a randomized controlled trial
Published 2025-04-01“…Secondary outcomes include changes in hypnotic medication use, Pittsburgh Sleep Quality Index (PSQI) scores, Piper Fatigue Scale (PFS) scores, and Functional Assessment of Cancer Therapy-Breast (FACT-B) scores. …”
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7280
Regional heterogeneity of the blood-brain barrier
Published 2025-08-01“…EC Stra6 regulates the deposition of retinoids specifically in the ShNAc and cochlear nucleus, and is required for the function of the ShNAc, in a retinoid-dependent manner. …”
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