Metabolic profiling and transcriptome analysis of Sinomenium acutum provide insights into the biosynthesis of structurally diverse benzylisoquinoline alkaloids by Xiuyu Liu, Jicong Chen, Rui Ma, Le Zhao, Conglong Lian, Suiqing Chen, Ying Ma

“…Transcriptome sequencing, functional annotation, and differential gene expression analysis were combined with metabolite profiling to predict biosynthetic pathways of structurally diverse BIAs and screen candidate genes. …”
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STRATEGIC POTENTIAL OF SUCCESSFUL COMMUNICATION WITHIN THE DISCURSIVE DIMENSION by Elena Grushevskaya

“…It is noted that the actualization of the strategic potential involves the implementation of various functions in the communication process, among which the priority function is the inluence function for persuasion. …”
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Non-Isothermal Degradation Kinetics of CaCO3 from Different Origin by Velyana Georgieva, Lyubomir Vlaev, Kalinka Gyurova

“…The kinetics and mechanism of their solid-state thermal decomposition reaction were evaluated from the TG data using four calculation procedures and isoconversion method, as well as 27 mechanism functions. The comparison of the results obtained with these calculation procedures showed that they strongly depend on the selection of proper mechanism function for the process. …”
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Metoda analizy statystycznej efektu kolmatacji i filtrowania by S. Borowik, B. Redmer

“…The method of statistical analysis of these phenomena proposed in the present paper is based on a simplified model of the colmatage process consisting in assuming that the particles of the liquid suspension considered (and characterized by a distribution density function) are spherical and that the structure of the porous body (described by two distribution density functions of pores: "geometric" and "hydraulic") is perfect. …”
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Hopf Bifurcation Analysis in a Modified Price Differential Equation Model with Two Delays by Yanhui Zhai, Ying Xiong, Xiaona Ma

“…Firstly, we modify the traditional price model by considering demand function as a downward opening quadratic function, and supply and demand functions both depending on the price of the past and the present. …”
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Mixed problem with integral conditions for a certain class of hyperbolic equations

“…We use a functional analysis method based on a priori estimate and on the density of the range of the operator generated by the considered problem.…”
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Geometry engineering of tunneling transistors in transition metal dichalcogenide nanoribbon heterojunctions by Ye Jiang, Minjiang Dan, Shuaiwei Fan, Gongwei Hu, Fobao Huang, Wei-Yang Wang, Qiao Chen

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Invariant natural killer T cells minimally influence gut microbiota composition in mice by Qiaochu Lin, Meggie Kuypers, Zhewei Liu, Julia K Copeland, Donny Chan, Susan J Robertson, Jean Kontogiannis, David S Guttman, E. Kate Banks, Dana J Philpott, Thierry Mallevaey

“…Invariant Natural Killer T (iNKT) cells are unconventional T cells that respond to glycolipid antigens found in microbes in a CD1d-dependent manner. iNKT cells exert innate-like functions and produce copious amounts of cytokines, chemokines and cytotoxic molecules within only minutes of activation. …”
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Pomolic acid induces ferroptosis-mediated cell death in non-small cell lung cancer by Wenbin Ji, Wenbin Ji, Yanbin Zhang, Yanbin Zhang, Wenhao Ji, Hui Zhang, Biao Qin, Biao Qin, Xiao-Liang Xing, Xiao-Liang Xing, Zaiqi Zhang, Zaiqi Zhang

“…In vitro functional studies were performed using NSCLC cells to investigate PA’s effects on cell death and proliferation. …”
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Melanoma-associated repair-like Schwann cells suppress anti-tumor T-cells via 12/15-LOX/COX2-associated eicosanoid production by Oleg Kruglov, Kavita Vats, Vishal Soman, Vladimir A. Tyurin, Yulia Y. Tyurina, Jiefei Wang, Li’an Williams, Jiying Zhang, Cara Donahue Carey, Erik Jaklitsch, Uma R. Chandran, Hülya Bayir, Valerian E. Kagan, Yuri L. Bunimovich

“…However, in vivo and ex vivo analyses of how cancers reprogram SC functions in different organs of tumor-bearing mice are lacking. …”
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Affordable Small Molecules as Promising Fluorescent Labels for Biomolecules by Raquel Eustáquio, João P. Prates Ramalho, Sílvia Arantes, António Candeias, Ana Teresa Caldeira, António Pereira

“…In this work, using 4-diethylaminobenzaldehyde as starting material, we developed a simple, cost-effective, and efficient synthetic strategy to produce new affordable small molecules as effective fluorescent labels for biomolecules. Density functional theory and time-dependent density functional theory calculations were also conducted to gain insights into the observed photophysical properties.…”
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Anatomy of the optic nerve based on cadaveric dissections and its neurosurgical approaches: a comprehensive review by R. López-Elizalde, M. Godínez-Rubí, Ya. Lemus-Rodríguez, E. Mercado-Rojas, T. Sánchez-Delgadillo, D. Sánchez-Delgadillo, A. Campero, R. G. Párraga

“…Therefore, surgical manipulation of the visual pathway requires a detailed knowledge of functional neuroanatomy. The aim of this review is to present the functional and microsurgical anatomy of the second cranial nerve, through illustrations and cadaveric dissections, to support the choice of the best surgical approach and avoid iatrogenic injuries. …”
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A facultative plasminogen-independent thrombolytic enzyme from Sipunculus nudus by Mingqing Tang, Guoxing Ma, Chunyan Xu, Hui Yang, Hongjun Lin, Chao Bian, Chengjia Hu, Meiling Lu, Lei Chen, Wencai Jie, Zhen Yue, Jianbo Jian, Yuqing Sun, Hui Yan, Jingjing Zhou, Xianying Zhang, Shengye Liao, Zhaofa Li, Shuangfeng Cai, Yaqing Wu, Kexin Yang, Yanan Xiong, Yonggang Zhao, Zhimin Lv, Xiaoming Xu, Chuang Liu, Pengliang Xin, Lichao Ye, Xiuling Cui, Qiong Shi, Xi Chen, Ruian Xu

“…Abstract Current thrombolytic therapies primarily function by converting plasminogen into plasmin, a process dependent on the fibrin–activator complex. …”
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The controversial role of CD151 in different solid tumors: promoter or suppressor? by Xue Gao, Sa Liu, Yubo Cao, Lei Shi, Yuanqin Yin

“…Notably, while CD151 predominantly functions as an oncogene in most cancers, it can also exhibit tumor-suppressive roles in specific contexts, indicating that its function is context-dependent. …”
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Prenatal Bisphenol A Exposure Impairs Fetal Heart Development: Molecular and Structural Alterations with Sex-Specific Differences by Alessandro Marrone, Anna De Bartolo, Vittoria Rago, Francesco Conforti, Lidia Urlandini, Tommaso Angelone, Rosa Mazza, Maurizio Mandalà, Carmine Rocca

“…Overall, our findings provide novel insights into the crucial role of prenatal endocrine disruption during fetal heart development and its contribution to the early origins of CVD, underscoring the urgent need for targeted preventive strategies and further research into the functional impact of BPA-induced alterations on postnatal cardiac function and long-term disease susceptibility.…”
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The impacts of polystyrene microplastics on development, energy transfer and nutrient cycling of biofilms: A comprehensive chronic toxicity study by Shuangshuang Li, Duo Xu, Yu Zheng, Heng Liu, Yan Song, Mingcan Cai, Chun Wang

“…To address this research gap, we investigated the impact of polystyrene microplastics (PS-MPs) on biofilm growth and development, with a particular focus on their effects on functional metabolism in freshwater environments. Using controlled long-term experiments, we explored the influence of PS-MPs at concentrations of 1, 10, and 100 mg/L over 52 days on microbial community structure, alpha and beta diversity and functional potential. …”
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An in vitro model for cardiac organoid production: The combined role of geometrical confinement and substrate stiffness by R. Santoro, L. Piacentini, C. Vavassori, P. Benzoni, G.I. Colombo, C. Banfi, A. Barbuti, G. Pompilio

“…The feasibility of recapitulating complex pathophysiological scenarios depends on iPSC's ability to differentiate into the plurality of specific organ resident cells, on their maturation and networking. …”
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TWO-YEAR MORTALITY PROFILE IN ELDERLY WITH FRAILTY : Observational Descriptive Study in Elderly Health Community in Surabaya, Indonesia by Ummi Ziyadatul Faizah, Novira Widajanti, Jusri Ichwani

“…Frailty raises the risk of death and health care costs, as well as functional disability, hospitalization, and fall risk. …”
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Understanding the impact related to lifestyle interventions for people with dementia: A systematic review protocol. by Laura Middleton, Vanessa Vucea-Tirabassi, Grace Liu, Jennifer Bethell, Heather Cooke, Heather Keller, Teresa Liu-Ambrose, Megan E O'Connell, Jackie Stapleton, Ingrid Waldron, Sarah Wu, Marie-Lee Yous, Christine Aiken, William Heibein, Myrna Norman, Carrie McAiney

“…The specific research questions are: "What is the effectiveness of physical activity interventions on improving functional abilities and quality of life among community-dwelling people living with dementia?"…”
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ERCC6L-mediated stabilization of HIF-1α enhances glycolysis and stemness properties of lung adenocarcinoma cells by Zhimin Lu, Xuming Yao, Jialu Jiang, Guoxin Hou

“…The ERCC6L/HIF-1α axis plays a crucial functional role in enhancing cancer stemness and LUAD progression both in vitro and in vivo. …”
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