Tumor endothelial cell autophagy is a key vascular‐immune checkpoint in melanoma by Jelle Verhoeven, Kathryn A Jacobs, Francesca Rizzollo, Francesca Lodi, Yichao Hua, Joanna Poźniak, Adhithya Narayanan Srinivasan, Diede Houbaert, Gautam Shankar, Sanket More, Marco B Schaaf, Nikolina Dubroja Lakic, Maarten Ganne, Jochen Lamote, Johan Van Weyenbergh, Louis Boon, Oliver Bechter, Francesca Bosisio, Yasuo Uchiyama, Mathieu JM Bertrand, Jean Christophe Marine, Diether Lambrechts, Gabriele Bergers, Madhur Agrawal, Patrizia Agostinis

“…Mechanistically, STING‐dependent immunity in TECs is not critical for the immunomodulatory effects of autophagy ablation, since NF‐kB‐driven inflammation remains functional in STING/ATG5 double knockout TECs. …”
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Time Matters: Methane Inhalation Mitigates Mitochondrial and Organ Dysfunction in Advanced Experimental Sepsis by Levente Frigyes Gulácsi, Attila Rutai, László Juhász, Bálint László Czakó, Andrea Szabó, Mihály Boros, József Kaszaki, Marietta Zita Poles, Szabolcs Péter Tallósy

“…This study aimed to characterize the time-dependent effects of methane (CH₄) inhalation, initiated at defined intervals following sepsis onset, on organ function, systemic oxygen utilization, and mitochondrial respiration in a rodent model. …”
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AAAP gene family evolution and transcriptional regulation in Eucalyptus grandis under nitrogen, phosphate and boron deficiencies by Jiahui Wei, Yi Han, Huiming Xu, Lichuan Deng, Lu Li, Shasha Zhang, Ting Jiang, Yunzhuo Feng, Liuyin Ma

“…Spatiotemporal expression profiling delineated six tissue-specific clusters and dynamic hormonal responses: SA/JA induced temporally distinct modules (early, sustained, delayed), while boron/nitrogen/phosphorus deficiency triggered subgroup- and tissue-dependent regulation. Conclusions Collectively, this study deciphers the evolutionary innovation, regulatory complexity, and functional specialization of AAAP transporters in Eucalyptus, providing a framework for understanding nutrient signaling and stress resilience in woody plants.…”
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Distribution characteristics of bacterial communities in central air-conditioning ventilation systems of a Grade 3A hospital in Shanghai based on 16S rRNA sequencing by Jun NI, Haiyun ZHANG, Jian CHEN, Lijun ZHANG, Yongping LIU, Xiaojing LI, Yiming ZHENG, Liping ZHANG

“…The diversity analysis indicated that bacterial community richness and diversity were highest in the condensate trays, while no statistically significant differences (P > 0.05) were observed in the bacterial community composition among the air outlets, filters, and surface coolers. The functional analysis showed that the bacterial communities in the central air-conditioning ventilation systems primarily exhibited chemoheterotrophic, oxidative energy-dependent heterotrophic, and ureolytic functional characteristics.ConclusionThe dominance of Proteobacteria suggests that this phylum exhibits strong adaptability in the central air-conditioning ventilation systems, possibly related to its ability to survive and reproduce under varying environmental conditions. …”
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A simple model of the rheological curve of HPAM solutions at different temperatures by Eduar Pérez, Dario Alviso, Mauricio Carmona, Eduardo Manrique, Guillermo Artana

“…The solvent viscosity and relaxation time-employed as references to define these parameters-are functions of temperature. On the master surface, while the power coefficient of Carreau-Yasuda (n) exhibits only a slight dependency on temperature, the relative viscosity depends monotonically on this variable. …”
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GNNs and ensemble models enhance the prediction of new sRNA-mRNA interactions in unseen conditions by Shani Cohen, Lior Rokach, Isana Veksler-Lublinsky

“…Abstract Bacterial small RNAs (sRNAs) are pivotal in post-transcriptional regulation, affecting functions like virulence, metabolism, and gene expression by binding specific mRNA targets. …”
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COMPENSATORY-ADAPTIVE MECHANISMS OF CHANGES IN THE ENDOTHELIAL SYSTEM IN MINERS OF KUZBASS (CLINICAL AND MORPHOLOGICAL ASPECTS) by Сергей Людовикович Кан, Олег Иванович Бондарев, Андрей Александрович Косовских, Константин Владимирович Лукашев, Олеся Сергеевна Золоева, Александр Владимирович Екимовских, Тамара Ивановна Борщикова, Денис Николаевич Макаров

“…The severity of systemic lesions with pathomorphological changes in the hemodynamic system were characteristic of many internal organs and depended on the length of work experience. Endothelial dysfunction was manifested by pronounced and progressive fibroplastic processes in the internal organs leading to functional and then structural changes. …”
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Hospital-to-home transitional care as support for older adult’s caregivers: a scoping review by Lélia Mendes Sobrinho de Oliveira, Larissa Chaves Pedreira, Ana Paula Santos de Jesus, Ivana Santos Pinto, Jeferson Moreira dos Santos, Larissa de Souza Correia, Ana Paula Bastos Nery, Nildete Pereira Gomes

“…ABSTRACT Objective: To explore, in the literature, how transitional care from hospital to home supports the caregivers of older adults with functional dependence. Method: Scoping review according to Joanna Briggs, with articles indexed in six databases and gray literature, from March to October 2022. …”
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CD103+ T Cells Eliminate Damaged Alveolar Epithelial Type II Cells Under Oxidative Stress to Prevent Lung Tumorigenesis by Yu Xu, Haorui Luo, Jiahao Wang, Haifeng Liu, Luonan Chen, Hongbin Ji, Zimu Deng, Xiaolong Liu

“…The reduction of CD103+ T cells in the lung results in an accumulation of AT2 cells bearing oxidative damages, which appears to be the major origin of the lung adenocarcinoma. Functional experiments reveal CD103+ T cells can eradicate oxidative‐damage‐bearing AT2 cells as well as ROS‐dependent, KRAS (G12D)‐driven tumorigenesis. …”
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Infections in Inborn Errors of STATs by Chen Wang, Alexandra F. Freeman

“…The susceptibility to pathogens can stem from defects in immune cells within the hematopoietic compartment, impaired barrier functions of non-hematopoietic compartment, or a combination of both, depending on the specific STAT defect as well as the pathogen exposure history. …”
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FKBP51 in glutamatergic forebrain neurons promotes early life stress inoculation in female mice by Lotte van Doeselaar, Alexandra Abromeit, Tibor Stark, Danusa Menegaz, Markus Ballmann, Shiladitya Mitra, Huanqing Yang, Ghalia Rehawi, Rosa-Eva Huettl, Joeri Bordes, Sowmya Narayan, Daniela Harbich, Jan M. Deussing, Gerhard Rammes, Michael Czisch, Janine Knauer-Arloth, Matthias Eder, Juan Pablo Lopez, Mathias V. Schmidt

“…In contrast, the behavioral, structural and functional effects in male ELS mice were less pronounced and independent of FKBP51. …”
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Extracellular vesicles as precision therapeutics for psychiatric conditions: targeting interactions among neuronal, glial, and immune networks by Ivana Kawiková, Ivana Kawiková, Ivana Kawiková, Václav Špička, James C. K. Lai, James C. K. Lai, Philip W. Askenase, Li Wen, Zdeněk Kejík, Zdeněk Kejík, Milan Jakubek, Milan Jakubek, Karel Valeš, Karel Valeš, Filip Španiel, Filip Španiel

“…The critical role of the immune system in brain function and dysfunction is well recognized, yet development of immune therapies for psychiatric diseases has been slow due to concerns about iatrogenic immune deficiencies. …”
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Regionally Specific Regulation of Sensorimotor Network Connectivity Following Tactile Improvement by Stefanie Heba, Melanie Lenz, Tobias Kalisch, Oliver Höffken, Lauren M. Schweizer, Benjamin Glaubitz, Nicolaas A. J. Puts, Martin Tegenthoff, Hubert R. Dinse, Tobias Schmidt-Wilcke

“…Correlations between inherent, task-free low-frequency fluctuations in the blood oxygenation level-dependent (BOLD) signals of the brain provide a potent tool to delineate its functional architecture in terms of intrinsic functional connectivity (iFC). …”
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PERHITUNGAN NUMERIK RAPAT KEADAAN GRAPHENE BILAYER DENGAN MODEL TIGHT-BINDING MENGGUNAKAN METODE RAMBATAN WAKTU TROTTER-SUZUKI by Wahyu Setiawan

“…The generation of the initial wave function  is carried out by using a random complex number as a superposition function of the base of each hexagonal structure atomic site to obtain the correlation function. …”
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Modeling of Kefir Production with Fuzzy Logic by Hüseyin Nail Akgül, Filiz Yıldız Akgül, Tuna Doğan

“…The first part consists of fuzzy rules and membership functions, while the second part consists of clarify. …”
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Semigroup Method on a MX/G/1 Queueing Model by Alim Mijit

“…By using the Hille-Yosida theorem, Phillips theorem, and Fattorini theorem in functional analysis we prove that the MX/G/1 queueing model with vacation times has a unique nonnegative time-dependent solution.…”
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SOME IMMUNOLOGICAL INDICATORS IN CERVICAL PATHOLOGY ASSOCIATED WITH PAPILLOMAVIRUS INFECTION by A. A. Savchenko, V. B. Tskhay, D. Yu. Kruglova, A. G. Borisov

“…To study immunological indices and functional activity of neutrophils in women with human papillomavirus infection (HPV), as well as their dependence on severity of cervical morphological alterations, we examined sixty-seven female patients in their reproductive age. …”
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The Ustilago maydis effector Pep1 suppresses plant immunity by inhibition of host peroxidase activity. by Christoph Hemetsberger, Christian Herrberger, Bernd Zechmann, Morten Hillmer, Gunther Doehlemann

“…Using cytological and functional assays we show that Pep1 functions as an inhibitor of plant peroxidases. …”
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ZNF385B as a potential prognostic and immunotherapy biomarker in ovarian cancer: insights from pan-cancer analysis by Hang Yu, Wei Cheng, Aoshuang Huang, Jing Feng, Dan Zi

“…Our analysis revealed that ZNF385B exhibits differential expression across various cancers and is associated with either favorable or unfavorable prognosis depending on the tumor type. Functional enrichment analyses suggest that ZNF385B is involved in critical cellular processes, such as transcriptional regulation, protein modification, and cellular localization. …”
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The insular cortex-nucleus tractus solitarius glutamatergic pathway involved in acute stress-induced gastric mucosal damage in rats by Zepeng Wang, Xinyu Li, Yuanyuan Li, Xuehan Sun, Yuxue Wang, Tong Lu, Dongqin Zhao, Xiaoli Ma, Haiji Sun

“…In this study, we examined the expression of neuronal c-Fos, PSD95 and SYN-1 protein expression in IC during RWIS by immunofluorescence and western blot techniques, as well as assessed IC blood oxygenation level dependant (BOLD) through functional MRI. Chemical genetics techniques specifically modulate the activity of IC glutamatergic neurons and IC-nucleus tractus solitary (NTS) glutamatergic pathway to elucidate their contributions to RWIS-induced gastric mucosal damage. …”
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