Endometrial microbiome in mares with and without clinical endometritis by Lulu Guo, G. Reed Holyoak, Udaya DeSilva

“…Linear discriminant analysis revealed Burkholderia, Hyphomicrobium, and Erwiniaceae as significantly enriched in CE. Functional pathway analysis showed increased metabolism-related pathways in CE-associated microbiota, while healthy mares exhibited greater microbial richness and functional diversity. …”
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Key role for store-operated Ca2+ channels in activating gene expression in human airway bronchial epithelial cells. by Krishna Samanta, Daniel Bakowski, Anant B Parekh

“…STIM1 and Orai1 mRNA transcripts as well as proteins were robustly in epithelial cells and formed functional Ca2+ channels. Ca2+ entry through the channels activated expression of c-fos and EGF as well as an NFAT-dependent reporter gene. …”
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Preparation, structure and properties of litchi pericarp polysaccharide by Yijie Wang, Gangliang Huang

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Overview of the Level of Activity Daily Living of the elderly who have chronic diseases in the Geriatric Polyclinic of the State General Hospital by Ni Wayan Suetri, Sang Ayu Ketut Candrawati, Ni Ketut Citrawati

“…Results:  The results of the study showed that of the 63 elderly people, the majority of the 39 elderly people (61.9%) who had chronic diseases experienced a mild level of dependence in carrying out daily living activities Conclusions:  Chronic diseases can affect the functional abilities of elderly people in living their daily lives. …”
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Design and Characterization of 2.5D Nature-Inspired Infill Structures under Out-Plane Quasi-Static Loading Condition by Dara Ashok, M. V. A. Raju Bahubalendruni

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Decoding Myosin-3 mutational hotspots: Linking deleterious variants to Duchenne muscular dystrophy severity and psychiatric comorbidities. by Mohammed Ageeli Hakami, Ahad Amer Alsaiari, Taj Mohammad, Anas Shamsi

“…This study employed various computational tools such as PolyPhen-2, SIFT, and I-Mutant to analyze 486 MYH3 missense mutations and predict the structural and functional implications. We discovered 89 deleterious substitutions, of which 80 were pathogenic. …”
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Impact of Baijiu geographical indication product certification on consumer purchasing behavior by WANG Kai, WU Mengli, TONG Jun

“…"Guizhou Moutai" (well-known domestic Baijiu brand) was selected as a case study subject, with consumer purchasing behavior as the dependent variable, and the functional value, emotional value, economic value, and safety value of product as independent variables, theoretical model was constructed based on consumer purchasing behavior theory. …”
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Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways by Mingqi CUI, Kaiwen YU, Yang SONG, Fangxu XU, Shenghou WANG, Ze WANG

“…These findings provide theoretical support for using C. militaris in functional foods.…”
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<i>FCGR2A</i>-131R Is Associated with Lupus Nephritis Rather than Non-Lupus Nephritis SLE in an Indigenous African Caribbean Population by Fatima Radouani, Christophe Deligny, Raymond Cesaire, Maryvonne Dueymes, Georges Dos Santos

“…Fc gamma receptors (FcγRs) control humoral and cellular immune responses and maintain the immune system balance. Functional polymorphisms of FcγRs, whose prevalence was dependent on ethnic origin, were found to be associated with systemic lupus erythematosus (SLE) or kidney injuries in several ethnic groups. …”
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Lytic coelomocyte death is tuned by cleavage but not phosphorylation of MLKL in echinoderms. by Kaiyu Chen, Sikou Shen, Zhimeng Lv, Ming Guo, Yina Shao, Chenghua Li

“…In this study, we identified a novel MLKL homolog containing a tetrapeptide recognition motif (14-LVAD-17) of inflammatory caspase from Apostichopus japonicus,which was absent of Gasdermins member by genome screening. Functional analysis revealed that AjMLKL was involved in the regulation of Vibrio splendidus AJ01 infection induced lytic coelomocyte death in a cleavage-dependent manner, but not through RIPK3-dependent phosphorylation as mammals. …”
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Design of a Path-Tracking Controller with an Adaptive Preview Distance Scheme for Autonomous Vehicles by Manbok Park, Seongjin Yim

“…In this paper, a preview function is introduced into the state-space model built for better path-tracking performance. …”
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Combining cross-sectional and longitudinal genomic approaches to identify determinants of cognitive and physical decline by Tabea Schoeler, Jean-Baptiste Pingault, Zoltán Kutalik

“…Focusing on global cognitive and physical function, we observed marked differences between baseline function (θ) and accelerated decline (Δ). …”
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Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice. by Shuqiu Zheng, Erin B D Clabough, Sovan Sarkar, Marie Futter, David C Rubinsztein, Scott O Zeitlin

“…Previous investigations into the role of the polyglutamine stretch (polyQ) in htt function have suggested that its length may modulate a normal htt function involved in regulating energy homeostasis. …”
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Experimental Investigation of the Power Consumption and Metzner–Otto Constant for Highly Shear-Thinning Fluids with Different Impeller Geometries by M. Jain, R. Misumi

“…During mixing, it is challenging to evaluate the power consumption for these fluids because the apparent viscosity (ηa), which is needed for the evaluation of the impeller Reynolds Number (Re), is a function of the shear rate, which itself is a function of the flow parameters.; the Metzner–Otto method is widely used to predict the ηa and average shear rate ([Formula: see text]) under these conditions. …”
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Robust genetic codes enhance protein evolvability. by Hana Rozhoňová, Carlos Martí-Gómez, David M McCandlish, Joshua L Payne

“…Whereas the genetic codes that optimize evolvability depend to some extent on the detailed relationship between amino acid sequence and protein function, we also uncover general design principles for engineering nonstandard genetic codes for enhanced and diminished evolvability, which may facilitate directed protein evolution experiments and the bio-containment of synthetic organisms, respectively.…”
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Teneurin-3 regulates the generation of non-image-forming visual circuitry and responsiveness to light in the suprachiasmatic nucleus. by John L Hunyara, K M Daly, Katherine Torres, Maria E Yurgel, Ruchi Komal, Samer Hattar, Alex L Kolodkin

“…Visual system function depends upon the elaboration of precise connections between retinal ganglion cell (RGC) axons and their central targets in the brain. …”
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Resin from Virola oleifera Protects Against Radiocontrast-Induced Nephropathy in Mice. by Igor Santos Fonte Bôa, Marcella Leite Porto, Ana Claudia Hertel Pereira, Jean Pierre Louzada Ramos, Rodrigo Scherer, Jairo Pinto Oliveira, Breno Valentim Nogueira, Silvana Santos Meyrelles, Elisardo Corral Vasquez, Denise Coutinho Endringer, Thiago Melo Costa Pereira

“…In this CIN model, pre-treatment with RV improved renal function, lowered the mortality rate, and reduced oxidative stress and apoptosis in both the medulla and cortex renal cells in a dose-dependent manner. …”
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Modern approaches to rehabilitation of military men with a gun-shot polystructural woundings of upper extremity by I. V. Roy, N. О. Borzykh, L. D. Каtіukova, О. V. Borzykh

“…Enhancement of the upper extremity function in military men, who obtained rehabilitation in accordance to the individual programs elaborated, was essentially bigger - (61.7 ± 12.1) points and achieved during shorter by (65.0 ± 14.0) days, than in the wounded persons, who obtained rehabilitation in accordance to standard procedures, the function enhancement have constituted (48.1 ± 11.2) points.…”
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Optimization of load frequency control using grey wolf optimizer in micro hydro power plants by Irvandy Ilza Novendra, I Made Wirawan, Arya Kusumawardana, Aung Ko Latt

“…The cost function that produces the smallest peak overshoot and peak undershoot parameter values varied depending on changes in the system load.…”
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The small GTPase MRAS is a broken switch by Gabriela Bernal Astrain, Regina Strakhova, Chang Hwa Jo, Emma Teszner, Ryan C. Killoran, Matthew J. Smith

“…Abstract Intense research on founding members of the RAS superfamily has defined our understanding of these critical signalling proteins, leading to the premise that small GTPases function as molecular switches dependent on differential nucleotide loading. …”
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