Interpretation of Local Flux Measurements in Subcritical Systems and Reactivity Determination by S. Dulla, P. Ravetto

“…Furthermore, the question of the generation of the effective source is analysed, and some proposals to modify the time dependence of such a function to account for the time delay at the flux detector are presented and discussed.…”
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Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development by Han Koo, Kyung Chan Park, Hyun Ahm Sohn, Minho Kang, Dong Joon Kim, Zee-Yong Park, Sehoon Park, Sang Hyun Min, Seong-Hwan Park, Yeon-Mi You, Yohan Han, Bo-Kyung Kim, Chul-Ho Lee, Yeon-Soo Kim, Sang J. Chung, Young Il Yeom, Dong Chul Lee

“…Here, we report that KRAS expression is post-translationally up-regulated through deubiquitination when the scaffolding function of NDRG3 (N-Myc downstream-regulated gene 3) promotes specific interaction between KRAS and a deubiquitinating enzyme, USP9X. …”
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Dexmedetomidine and the glymphatic system: a new perspective in managing postoperative cognitive dysfunction by Sha-Sha Zhang, Fan-Geng Meng, Yuan-Yuan Rong, Yi-Wen Zhang, Hua-Qin Liu

“…Dexmedetomidine (Dex), a selective α2-adrenergic receptor agonist, facilitates glymphatic function by mimicking non-REM sleep patterns and reducing central norepinephrine tone. …”
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Patient Reported Outcomes Following Triple Arthrodesis for Adult Acquired Flat Foot Deformity: Minimum Two Year Follow Up by Tyler Kelly, Ashish Shah MD, Mila Scheinberg MD, MS

“…The purpose of this study was to identify patient-specific variables that independently influence PROMIS, Foot Function Index (FFI), and VAS scores as well as complication rates. …”
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Mending the Valve, Burdening the Kidney: A Case of Renal Hemosiderosis With Mitral Valve Repair by Sadikshya Bhandari, Tenzin Tamdin, Raymond Raut

“…Due to persisting anemia and worsening kidney function, the patient is being planned for a mitral valve replacement. …”
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Bridging the 3D geometrical organisation of white matter pathways across anatomical length scales and species by Hans Martin Kjer, Mariam Andersson, Yi He, Alexandra Pacureanu, Alessandro Daducci, Marco Pizzolato, Tim Salditt, Anna-Lena Robisch, Marina Eckermann, Mareike Töpperwien, Anders Bjorholm Dahl, Maria Louise Elkjær, Zsolt Illes, Maurice Ptito, Vedrana Andersen Dahl, Tim B Dyrby

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M1/M2 macrophages: origin, phenotype, methods of production, interaction with natural killer cells and trophoblast by A. S. Zhguleva, M. S. Zementova, S. A. Selkov, D. I. Sokolov

“…The review presents methods and approaches to obtaining polarized macrophages in vitro from both peripheral blood monocytes and cells of transplanted cultures based on signals received by macrophages in vivo; the phenotype, cytokine production and functional properties of artificially polarized macrophages depending on the conditions of their production are given. …”
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Effect of testosterone in young ice-hockey players on hematological, biochemical parameters and the level of physical performance by N. V. Aksenova, T. A. Mangushev, P. L. Okorokov, E. V. Babaeva, I. V. Zyabkin

“…The values of other biomarkers of the functional activity of muscle tissue did not depend on the level of testosterone levels.Conclusion: Increased serum testosterone level in the range from 27.5 to 40 nmol/l, detected in young ice-hockey players aged 15–17 years, is not associated with a change in hematological and biochemical parameters. …”
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Simple methods for determination of the acoustical properties of ground surfaces by Roman GOŁĘBIEWSKI

“…For the simplified model of the ground effect, the adjustable parameters are given as a function of the effective flow resistivity. Similarly for the ground effect model given by ISO 9613, the dependence of the ground factor (as a function of the effective flow resistivity) is presented. …”
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Formulation of a Yield Surface for Sand Based on the Elastic Threshold Strain by Sang Inn Woo

“…The new yield function was calibrated for Toyoura sand. The calibration results show that the proposed yield surfaces are nonlinear curves that depend on the void ratio of sand in the p′-q plane, whereas the linear lines have been adopted in the bounding surface modeling of sand. …”
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miR-132/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity. by Judit Remenyi, Mirjam W M van den Bosch, Oleg Palygin, Rajen B Mistry, Colin McKenzie, Andrew Macdonald, Gyorgy Hutvagner, J Simon C Arthur, Bruno G Frenguelli, Yuriy Pankratov

“…Together these results indicate that miR-132 and/or miR-212 play a significant role in synaptic function, possibly by regulating the number of postsynaptic AMPA receptors under basal conditions and during activity-dependent synaptic plasticity.…”
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Performance Analysis of Diabetes Detection Using Machine Learning Classifiers by Hung Huynh, Liu Hui, Ngoc Han Nguyen, Ruixuan Qiao

“…Three types of machine learning classifiers are used: Tree-based, Function-based, and Rule-based. Results have shown that Stochastic Gradient Descent (function), Logistic Regression (function), JRip (rules) and Random Forests (trees) are among the top performing classifiers. …”
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Generalized volume-complexity for Lovelock black holes by Monireh Emami, Shahrokh Parvizi

“…Additionally, we discuss the late time behavior, focusing on proportionality of the complexity time rate to the difference of temperature times entropy at the two horizons $$(TS(r_+)-TS(r_-))$$ ( T S ( r + ) - T S ( r - ) ) for charged black holes, which can be corrected by generalization function of each radius in generalized case. In this limit, we also explore near singularity structure by approximating spacetime to Kasner metrics and finding possible values of complexity growth rate with different choices of the generalization function.…”
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From Microcirculation to Aging-Related Diseases: A Focus on Endothelial SIRT1 by Martin Law, Pei-Chun Wang, Zhong-Yan Zhou, Yu Wang

“…Its protective function in aging-related diseases has been extensively studied. …”
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Restrictive Cardiomyopathies: The Importance of Noninvasive Cardiac Imaging Modalities in Diagnosis and Treatment—A Systematic Review by Aidonis Rammos, Vasileios Meladinis, Georgios Vovas, Dimitrios Patsouras

“…CMR offering a higher spatial resolution than echocardiography can provide detailed information about anatomic structures, perfusion, ventricular function, and tissue characterization. CMR with late gadolinium enhancement (LGE) and novel approaches (myocardial mapping) can direct the diagnosis to specific subtypes of RCM, depending on the pattern of scar formation. …”
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The Female Athlete by Schwalm LC, Bäcker S, Weisser B, Kusche-Vihrog K

“…Of note, only young subjects benefited from a greater increase in performance regarding vascular function. However, further investigations are needed to clarify whether this result is based on an age-dependent, longer regeneration time.Key Words: Physical Exercise, Glycocalyx, Pulse Wave Velocity, Cardiovascular Fitness…”
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Lipocalin 2 in Obesity and Diabetes: Insights into Its Role in Energy Metabolism by Erik Lindstrom, Jessica Deis, David A. Bernlohr, Xiaoli Chen

“…Conclusions: This review provides an up-to-date summary of LCN2’s multifaceted roles in obesity, diabetes, energy balance, and mitochondrial function, emphasizing its context-dependent effects. …”
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Quality of life in patients after cystectomy as the main aim while making a choice for the urine derivation procedure by R. V. Savchuk, F. I. Kostуev, S. V. Golovko

“…All the QL indices in the groups investigated have improved in 12 mo postoperatively, what witnesses about progressing social rehabilitation, not depending upon the kind of the urine derivation. The method of the urine derivation do not influences erectile function, and the main significance is gaining the preservation of nervous and vascular elements of a small pelvis. …”
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Grass carp Trim47 restricts GCRV infection via SPRY domain-mediated autophagic degradation of nonstructural proteins and disruption of viral inclusion bodies by Wei Yan, Wei Yan, Yang Chen, Yang Chen, Dong Yan, Dong Yan, Jie Zhang, Jie Zhang, Ming Xian Chang, Ming Xian Chang

“…Unlike mammalian TRIMs, gcTrim47 antiviral activity is strictly dependent on its SPRY domain—devoid of RING/B-box domains critical for E3 ligase function—revealing an evolutionarily divergent mechanism where substrate-targeting specificity, not ubiquitination, drives viral replication factory (viral inclusion body, VIB) dismantling. …”
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Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life by Natalie Papachristoforou, Natalia Tekiela, Daria Michałka, Zuzanna Gałuszka, Monika Makar, Tomasz Bartuś, Emilia Bąk, Justyna Głowacka, Aleksandra Kocjan, Radosław Chmiel

“…Pharmacological strategies involve dopaminergic medications, low-potency opioids, and benzodiazepines, with a target on minimizing side effects and dependency. Conclusion: RLS affects approximately 5-10% of the population, severely disrupting sleep and daily functioning. …”
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