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6541
Genome-wide analysis of alternative splicing differences in hepatic ischemia reperfusion injury
Published 2024-12-01“…A total of 898 DAS genes (p ≤ 0.05) were screened out in the hepatic IR group compared to the sham group, while functional enrichment analysis revealed that DETs and DAS genes were significantly associated with the ATP-dependent chromain, splicesome and metabolic pathways. …”
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6542
Ca2+ signaling in vascular smooth muscle and endothelial cells in blood vessel remodeling: a review
Published 2024-12-01“…Coupled with endothelial dysfunction blood vessels undergo functional remodeling characterized by enhanced vasoconstriction. …”
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6543
MODELING LONGITUDINAL MEASUREMENTS OF CLINICAL AND EPIDEMIOLOGICAL PARAMETERS USING JOINPOINT REGRESSION
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6544
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6545
Reconstruction of postoperative defects using carbon nanostructured implants with intramedullary osteosynthesis after extremity long bone resection for primary and metastatic tumor...
Published 2022-06-01“…Reconstruction of bone defects after resection of long bones is critical for successful functional limb salvage. The choice of the reconstruction technique depends on the tumor location, tumor extension, presence of pathological fracture, and somatic status of the patient. …”
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6546
T cell responses induced by adenoviral vectored vaccines can be adjuvanted by fusion of antigen to the oligomerization domain of C4b-binding protein.
Published 2012-01-01“…We demonstrate that i) C-terminal fusion of an oligomerization domain can enhance the quantity of antigen-specific CD4(+) and CD8(+) T cell responses induced in mice after only a single immunization of recombinant AdHu5, and that the T cells maintain similar functional cytokine profiles; ii) an adjuvant effect is observed for AdHu5 vectors expressing either the 42 kDa C-terminal domain of Plasmodium yoelii merozoite surface protein 1 (PyMSP1(42)) or the 83 kDa ectodomain of P. falciparum strain 3D7 apical membrane antigen 1 (PfAMA1), but not a candidate 128kDa P. falciparum MSP1 biallelic fusion antigen; iii) following two homologous immunizations of AdHu5 vaccines, antigen-specific T cell responses are further enhanced, however, in both BALB/c mice and New Zealand White rabbits no enhancement of functional antibody responses is observed; and iv) that the T cell adjuvant activity of C4 bp is not dependent on a functional Fc-receptor γ-chain in the host, but is associated with the oligomerization of small (<80 kDa) antigens expressed by recombinant AdHu5. …”
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6547
Evaluating LiDAR‐Derived Structural Metrics for Predicting Bee Assemblages in Managed Forests
Published 2025-04-01“…ABSTRACT Globally, many insects depend on forest habitat for critical nesting and floral resources. …”
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6548
Augmented virtuality technology in education: taxonomy of augmented virtuality types
Published 2024-12-01“…The copy is a virtual copy display without functional changes, presented as a 3D model instead of a real object. …”
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6549
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6550
Identification, characterization and expression analysis of the CDPK family in kelp Saccharina japonica
Published 2025-08-01“…Given its independent taxonomic position, brown algae CDPKs might exhibit unique structural and functional characteristics in ecological adaptation. …”
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6551
On Complex Singularity Analysis for Some Linear Partial Differential Equations in
Published 2013-01-01“…We construct these solutions with the help of series of functions with infinitely many variables which involve derivatives of all orders of X in one variable. …”
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6552
Perspective on the Biomimetic Approaches for the Design of Hydrophobic and Antimicrobial Paper Coatings with Hierarchical Surface Structures
Published 2025-04-01“…The design of functional paper coatings with excellent barrier properties, including water repellence, anti-microbial properties, and recyclability, is highly demanded in view of the sustainable use of paper as flexible substrates for various industrial applications such as packaging. …”
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6553
Reliability based assessment of reinforced concrete columns under eccenric loads using refined first-order reliability method
Published 2024-03-01“…The effect of longitudinal reinforcement varies depending on the probability density function of the load eccentricity and the region of the interaction diagram where the column is loaded.…”
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6554
VMP1 attenuates ferroptosis and mitochondrial dysfunction in nucleus pulposus cells through the PINK1/Parkin-mediated mitophagy pathway
Published 2025-07-01“…Furthermore, we demonstrated that VMP1 silencing promoted ferroptosis, inhibited PINK1/Parkin-dependent mitophagy, and impaired mitochondrial function in NPCs. …”
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6555
New Perspectives on Postmenopausal Osteoporosis: Mechanisms and Potential Therapeutic Strategies of Sirtuins and Oxidative Stress
Published 2025-05-01“…SIRTs are enzymes that function as NAD+-dependent deacetylases. SIRTs can modulate osteocyte function, sustain mitochondrial homeostasis, and modulate relevant signaling pathways, thereby improving bone metabolic imbalances, reducing bone resorption, and promoting bone formation. …”
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6556
Single-cell sequencing reveals transcriptional dynamics regulated by ERα in mouse ovaries.
Published 2024-01-01“…Greb1 expression in granulosa cells was found to be ERα-dependent.<h4>Conclusions</h4>ERα deletion significantly alters the transcriptional landscape of ovarian cells, affecting genes and pathways central to ovarian function and the ovulation process.…”
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6557
Theoretical background of the operating parameters of the satellite working mechanism of the hydraulic positive displacement machine
Published 2025-04-01“…The results of the tests confirmed that the torque on the shaft is not constant in both pump and motor operation at a constant pressure drop in this machine. This torque depends strictly on the instantaneous working volume of the machine and is therefore a function of the angle of rotation of the shaft. …”
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6558
Examining changes in gramicidin current induced by endocannabinoids.
Published 2025-01-01“…In addition to acting as agonists to cannabinoid receptors (CBRs), endocannabinoids can also modulate the function of various ion channels and receptors independently of CBRs. …”
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6559
A putative cation channel, NCA-1, and a novel protein, UNC-80, transmit neuronal activity in C. elegans.
Published 2008-03-01“…Its localization and function depend on UNC-79, and UNC-80, a novel conserved protein that is also enriched at nonsynaptic regions. …”
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6560
Entanglement asymmetry in periodically driven quantum systems
Published 2025-08-01“…Our results show that for $m$ cycles of a periodic drive with time period $T$, $\Delta S \sim \ln mT$ [$\ln (\ln mT)$] in the heating phase [on the critical line] for a generic CFT; in contrast, in the non-heating phase, $\Delta S$ displays small amplitude oscillations around it's initial value as a function of $mT$. We provide a phase diagram for the behavior of $\Delta S$ for such driven CFTs as a function of the drive frequency and amplitude.…”
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