M2 Macrophage‐Derived sEV Regulate Pro‐Inflammatory CCR2+ Macrophage Subpopulations to Favor Post‐AMI Cardiac Repair by Lan Li, Jiasong Cao, Sheng Li, Tianyi Cui, Jingyu Ni, Han Zhang, Yan Zhu, Jingyuan Mao, Xiumei Gao, Adam C. Midgley, Meifeng Zhu, Guanwei Fan

“…Taken together, this investigation showed that M2EV rescued myocardial function, improved myocardial repair, and regulated CCR2+ macrophages via miR‐181b‐5p‐dependent mechanisms, indicating an option for cell‐free therapy for AMI.…”
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CD155 as a therapeutic target in alveolar echinococcosis: insights from an Echinococcus multilocularis infection mouse model by Xue Zhang, Liang Li, Tao Sun, Ning Yang, Hui Liu, Jin Chu, Junlong Xue, Guodong Lü, Tuerganaili Aji, Xiaojuan Bi, Renyong Lin, Renyong Lin

“…The infected group showed significantly reduced percentages of functional CD4+IFN-γ+, CD4+CD107a+, and CD8+CD107a+ T cells (p < 0.05), along with enrichment of exhausted TIGIT+ T cells adjacent to CD155+ hepatocytes. …”
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Application of physics-informed neural networks for two-phase flow model with variable diffusion and experimental validation by Daulet Kalesh, Timur Merembayev, Sagyn Omirbekov, Yerlan Amanbek

“…This paper presents Physics-Informed Neural Networks (PINNs) with a spatially-dependent diffusion function to model two-phase flow in porous media, explicitly addressing the Buckley-Leverett problem. …”
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Shrinkage effect on radial and tangential direction stresses in cylindrical wood pieces of Pinus taeda by Nilson Tadeu Mascia

“…Assuming constant longitudinal strains, the strain components can be described as a function of Lekhnitskii’s reduced strain coefficients and the associated coefficient, denoted by k, where the coefficients depend on the material's elastic properties. …”
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Interleukin-2 gene promoter polymorphism (T330G) and lymphocyte platelet adhesion in influenza A (H3N2) by G. A. Chuprova, A. N. Emel’yanova, A. S. Emel’yanov, Yu. A. Vitkovskii

“…Study of the lymphocyte-platelet adhesion function in patients with influenza A (H3N2) depending on polymorphic variants of the IL-2 gene promoter (T330G).Materials and methods. …”
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Parameter Estimation and Forecasting Strategies for Cholera Dynamics: Insights from the 1991–1997 Peruvian Epidemic by Hamed Karami, Gerardo Chowell, Oscar J. Mujica, Alexandra Smirnova

“…This study focuses on stable parameter estimation and forecasting of cholera outbreaks using a compartmental SIRB model informed by three formulations of the environmental transmission rate: (1) a pre-parameterized periodic function, (2) a temperature-driven function, and (3) a flexible, data-driven time-dependent function. …”
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Effect of Corrosion Damage on the Performance Level of a 25-Year-Old Reinforced Concrete Building by Hakan Yalciner, Serhan Sensoy, Ozgur Eren

“…In this study, a corroded, 25-year-old high school building which has been demolished at an earlier time was analyzed as a function of corrosion rate. Bond-slip relationships were taken into account in nonlinear analyses as a function of corrosion rate for different time periods (i.e., non-corroded (t: 0), existing (t: 25) and 50 years after construction); and they were used to ensure the effect of time-dependent slip rotation on the global structural behaviour by modifying the target post-yield stiffness of each structural member. …”
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BRD4 acts as a transcriptional repressor of RhoB to inhibit terminal erythropoiesis by Yijin Chen, Dawei Huo, Ye Meng, Jie Zhang, Mengmeng Huang, Qian Luo, Yulin Xu, Haiqiong Zheng, Yingli Han, Xiangjun Zeng, Yanjuan Liu, Yunfei Liu, Rui Wen, Delin Kong, Ruxiu Tie, Shanshan Pei, Nan Liu, Pengxu Qian, He Huang, Meng Zhang

“…Unexpectedly, this BRD4 function was independent of its classical CDK9 interaction and transcriptional activation. …”
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KERNEL DETERMINATION PROBLEM FOR ONE PARABOLIC EQUATION WITH MEMORY by Durdimurod K. Durdiev, Javlon Z. Nuriddinov

“…This paper studies the inverse problem of determining a multidimensional kernel function of an integral term which depends on the time variable \(t\) and \((n-1)\)-dimensional space variable \(x'= \left(x_1,\ldots, x_ {n-1}\right)\) in the \(n\)-dimensional diffusion equation with a time-variable coefficient at the Laplacian of a direct problem solution. …”
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Field switching of microfabricated metamagnetic FeRh MRI contrast agents by Stephen Dodd, Natalia Gudino, Oleksii Zadorozhnii, Michal Staňo, Jan Hajduček, Jon Ander Arregi, H. Douglas Morris, Vojtěch Uhlíř, Mladen Barbic, Alan P. Koretsky

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Phylogroup Homeostasis of <i>Escherichia coli</i> in the Human Gut Reflects the Physiological State of the Host by Maria S. Frolova, Sergey S. Kiselev, Valery V. Panyukov, Olga N. Ozoline

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Potential ecosystem services aquatic insects provide in irrigated rice fields under different cultivation regimes by Pauline Amanda Vognach, Mateus Marques Pires, Marina Schmidt Dalzochio, Eduardo Périco

“…A framework was implemented based on functional traits and the ecological functions performed by each taxon. …”
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BIOMECHANICAL STUDY OF SINGLE ROOTED TEETH RESTORED WITH DOWEL CORS by M. M. Klepach, B.Y. Silenko, T. A. Khmil, M. V. Khrebor, Y. I. Silenko

“…As a result of mathematical analysis of a model system “the root of the tooth, dowel core, crown” found that the horizontal component of the functional load and the combined effect of vertical and horizontal components of the load leads to the localization of fields of maximum values of equivalent stresses in the middle third of the pin of the dowel core from the vestibular or oral side, depending on the direction of the horizontal load. …”
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Real-time scattering in Ising field theory using matrix product states by Raghav G. Jha, Ashley Milsted, Dominik Neuenfeld, John Preskill, Pedro Vieira

“…In the postcollision wave function, particle tracks from all final-state channels occur in superposition; processes of interest can be isolated by projecting the wave function onto definite particle sectors, or by evaluating energy density correlation functions. …”
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Thermocouple Sensor Response in Hot Airstream by Jacek Pieniazek

“…The results obtained at several calculation points show the influence of the stream outflow velocity and selected geometric parameters on the value of the transfer function coefficients, i.e., transfer function gain and time constant. …”
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Mitogen-activated protein kinase 6 negatively regulates secondary wall biosynthesis by modulating MYB46 protein stability in Arabidopsis thaliana. by Jong Hee Im, Jae-Heung Ko, Won-Chan Kim, Brent Crain, Daniel Keathley, Kyung-Hwan Han

“…The R2R3-MYB transcription factor MYB46 functions as a master switch for secondary cell wall biosynthesis, ensuring the exquisite expression of the secondary wall biosynthetic genes in the tissues where secondary walls are critical for growth and development. …”
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Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells. by Joseph Landry, Alexei A Sharov, Yulan Piao, Lioudmila V Sharova, Hua Xiao, Eileen Southon, Jennifer Matta, Lino Tessarollo, Ying E Zhang, Minoru S H Ko, Michael R Kuehn, Terry P Yamaguchi, Carl Wu

“…Histological analyses of lineage markers show that Bptf(-/-) embryos implant but fail to establish a functional distal visceral endoderm. Microarray analysis at early stages of differentiation has identified Bptf-dependent gene targets including homeobox transcriptions factors and genes essential for the development of ectoderm, mesoderm, and both definitive and visceral endoderm. …”
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The R-RAS2 GTPase is a signaling hub in triple-negative breast cancer cell metabolism and metastatic behavior by Claudia Cifuentes, Lydia Horndler, Pilar Grosso, Clara L Oeste, Alejandro M. Hortal, Jennifer Castillo, Isabel Fernández-Pisonero, Alberto Paradela, Xosé Bustelo, Balbino Alarcón

“…Additionally, we developed a TNBC cell line from RRAS2-overexpressing mice, enabling loss-of-function studies to investigate the role of R-RAS2 in various pathobiological parameters of TNBC cells, including cell migration, invasiveness, metabolic activity, and metastatic spread. …”
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New insights into the mechanism of triphenyl phosphate and its metabolite diphenyl phosphate in diabetic kidney disease by Ting Fang, Qiaoyan Liu, Xinxin Huangfu, Hongkai Zhu, Hongwen Sun, Liming Chen

“…The research examined the relationship between urinary DPHP levels and kidney function in American adults using data from the National Health and Nutrition Examination Survey (NHANES) from 2017 to March 2020. …”
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Ubiquitin-Specific Protease Inhibitors for Cancer Therapy: Recent Advances and Future Prospects by Mohamad Bakkar, Sara Khalil, Komal Bhayekar, Narva Deshwar Kushwaha, Amirreza Samarbakhsh, Sadaf Dorandish, Holly Edwards, Q. Ping Dou, Yubin Ge, Navnath S. Gavande

“…Particular attention is given to the role of USP inhibitors in enhancing cancer immunotherapy, e.g., modulation of the tumor microenvironment, effect on regulatory T cell function, and influence on immune checkpoint pathways. …”
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