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6381
The Intuitionistic Fuzzy Linguistic Cosine Similarity Measure and Its Application in Pattern Recognition
Published 2018-01-01“…The main advantage of the proposed cosine similarity measures is that the decision-makers can flexibly select the linguistic scale function depending on the actual semantic situation. …”
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6382
Minimax Results with Respect to Different Altitudes in the Situation of Linking
Published 2013-01-01“…Consider a continuous function on a metric space. In the presence of linking between a compact pair and a closed set, depending on the different behaviors of the function on the linking sets, we establish minimax results guaranteeing existence of Palais-Smale sequences or providing gradient estimates. …”
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6383
Modification of the FoxP3 transcription factor principally affects inducible T regulatory cells in a model of experimental autoimmune encephalomyelitis.
Published 2013-01-01“…Interestingly, Treg cell function can be negatively or positively affected, depending on the nature of the model. …”
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6384
Chronic NaHS Treatment Is Vasoprotective in High-Fat-Fed ApoE−/− Mice
Published 2013-01-01“…Hydrogen sulfide is emerging as an important mediator of vascular function that has antioxidant and cytoprotective effects. …”
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6385
The Gr64 cluster of gustatory receptors promotes survival and proteostasis of epithelial cells in Drosophila.
Published 2022-07-01“…Using heterozygous mutations in ribosome proteins (Rp), which have recently been shown to induce proteotoxic stress and protein aggregates in cells, we show that Rp/+ cells in Drosophila imaginal discs up-regulate expression of the entire Gr64 cluster and depend on these receptors for survival. We further show that loss of Gr64 in Rp/+ cells exacerbates stress pathway activation and proteotoxic stress by negatively affecting autophagy and proteasome function. …”
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6386
Activity of tissue enzymes of the liver and peripheral blood lymphocytes at children with chronic hepatitis B
Published 2010-02-01“…Metabolic reactions in liver tissue of children depend on stage of chronization of process, at the 3-rd stage the functional lesion of liver cells it is more profound. …”
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6387
CTRP3 attenuates myocardial lipotoxicity via suppression of lipid accumulation, inflammation, apoptosis, and mitochondrial oxidative stress
Published 2025-05-01“…These coordinated effects substantially ameliorated lipotoxic myocardial damage and improved cardiac functional parameters.ConclusionOur findings reveal that CTRP3 confers robust protection against myocardial lipotoxicity through multi-modal mechanisms involving lipid metabolism regulation, anti-inflammatory actions, apoptosis inhibition, and oxidative stress mitigation, highlighting its therapeutic potential for metabolic cardiomyopathy.…”
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6388
Elucidating molecular pathogenesis and developing targeted therapeutic interventions for cerebrovascular endothelial cell-mediated vascular dementia
Published 2025-07-01“…The maintenance of neurological function and cerebral homeostasis critically depends on precisely regulated blood flow within the intricately organized cerebrovascular network. …”
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6389
METTL1-mediated m7G tRNA modification drives papillary thyroid cancer progression and metastasis by regulating the codon-specific translation of TNF-α
Published 2025-05-01“…Here, we found that METTL1 is significantly upregulated in PTC tissues compared to normal control tissues and is associated with poor PTC prognosis. Functional analysis confirmed that METTL1 promotes the proliferation and metastasis of PTC cells in a manner dependent on its tRNA methyltransferase activity. …”
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6390
Moya-moya disease in a child with nephropatic cystinosis: a case report and literature review
Published 2025-01-01“…The disease is characterized by renal (Fanconi syndrome with progressive decline in renal function) and extrarenal manifestations in the form of hypothyroidism, hypogonadism, insulin-dependent diabetes mellitus, coronary vascular calcification, metabolic bone disease, damage to the central nervous system with cortical atrophy, cerebral calcification and etc.Moya-moya disease is a progressive condition that can lead to ischemic stroke or intracranial hemorrhage in children and adults. …”
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6391
Early diagnosis and treatment of low-grade myofibroblastic sarcoma in the left distal femur: a case report and literature review
Published 2025-07-01“…Postoperatively, the patient reported significant pain relief and functional recovery at five months, with VAS, WOMAC, and HSS scores indicating improved joint function. …”
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6392
SRBD1, a highly conserved gene required for chromosome individualization
Published 2025-04-01“…Summary: Despite significant progress made in functional genomics, the roles of a relatively small number of essential genes remain enigmatic. …”
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6393
FEATURES OF LUMINOL- AND LUCIGENIN-INDUCED CHEMILUMINESCENCE OF NEUTROPHILIC GRANULOCYTES IN PATIENTS WITH CHRONIC RHINOSINUSITIS
Published 2014-07-01“…Studies of functional activity of neutrophilic granulocytes from patients with chronic rhinosinusitis was performed using luminol- or lucigenin-dependent chemiluminescence. …”
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6394
Restoration of antibiotic associated diarrhea induced gut microbiota disorder by using Dictyophora indusiata water-insoluble polysaccharides in C57BL/6J mice
Published 2025-07-01“…Also, compared with the NR group, DIPY increasing the relative abundance of Parasutterella and Blautia, increasing the production of acetic acid (p < 0.001), and decreasing the levels of LPS, MCP-1, TNF-α, and IL-6 (p < 0.05) which attenuating inflammatory responses.ConclusionThis study demonstrated that DIPY has intestinal prebiotic function, which provides a basis for further development of functional products for the treatment of AAD.…”
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6395
Electrical stimulation of the dorsolateral prefrontal cortex inhibits vestibular signalling in humans: A BOLD fMRI study
Published 2025-05-01“…Methods: To identify the sites of this interaction, blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging (fMRI) was collected whilst simultaneously delivering sinusoidal electrical stimulation (±2 mA, 0.2 Hz, 60 cycles) to 20 participants. …”
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6396
Impact of surface treatments on the photocatalytic performance of anodic aluminum oxide templates
Published 2025-04-01“…In contrast, the performance of templates functionalized with Fe2O3 as an inherent chemically instable photocatalyst depends on the template stability. …”
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6397
Optimal Control against the Human Papillomavirus: Protection versus Eradication of the Infection
Published 2019-01-01“…We formulate optimal control problems complementing our model with two different objective functionals. The first functional corresponds to the protection of the vulnerable group and the control problem consists of minimizing the cumulative level of infected females over a fixed time interval. …”
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6398
Quality of life in individuals with spinocerebellar ataxia type 10: a preliminary study
“…The longer the disease duration (p = 0.02), risk of falling (p = 0.04), severity of ataxia (p = 0.00) and functional dependence in activities of daily living (p = 0.03) and instrumental activities of daily living (p = 0.00), the worse the QoL was in the “physical functioning” domain, with a decrease of 1.62 points for each year of disease duration. …”
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6399
A Prospective Controlled Study on the Longitudinal Effects of Rehabilitation in Older Women with Primary Sarcopenia
Published 2025-04-01“…Sarcopenia, defined as a progressive loss of skeletal muscle mass, strength, and function, is a leading contributor to disability, dependence, and reduced quality of life (HRQoL) in older adults. …”
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6400
Nordihydroguaiaretic acid inhibits bladder cancer metastasis through suppression of α1,3-mannosyltransferase expression and LRFN4 N-glycosylation
Published 2025-07-01“…This study investigates the functional role of glycosylation in cancer progression and explores its therapeutic potential. …”
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