Aircraft maintenance system simulation mathematical model construction by Yu. I. Samulenkov, Ya. A. Filatova, A. D. Gruzd

“…For example, modern medium haul aircraft are fitted with up to 25,000 sensors to monitor the performance capabilities of functional systems components. Numerous ground-based instrumental methods and means of diagnosing the technical condition are used. …”
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Serum Positive for the Autoantibody against the β1-Adrenoceptor from Chinese Patients with Congestive Heart Failure Decreases Iss in Mouse Cardiac Myocytes by Yuan-yuan Wang, Zhi-Yong Ma, Xiao-Dong Li, Jian-chun Wang, Wei Zhang, Li Li, Yun Zhang

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The relationship between fetuin-A level and the clinical features of patients with coronary artery disease associated with iron deficiency by M. O. Konovalova, N. S. Mykhailovska

“…All patients were divided into 4 clinical groups depending on the parameters of iron metabolism and hemogram: I (n = 16) – patients with absolute ID, II (n = 15) – with latent ID, III (n = 14) – with functional ID; IV (n = 45) – patients CAD without iron metabolism disorders. …”
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Estimation of the equivalent dose rate of gamma radiation in the open territory of the city of Voronezh by Mikhail I. Chubirko, Oleg V. Klepikov, Semen A. Kurolap, Maksim K. Kuzmichev, Ekaterina M. Studenikina

“…The aim of the study was to identify patterns of distribution of the magnitude of the the equivalent dose rate of gamma radiation in an open area of urban space, depending on the functional purpose of the inner-city territory and the type of artificial coating. …”
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Long-Term Results of the Treatment of Mallet Finger Injuries: A Retrospective Analysis by Yulia S. Volkova, Liubov A. Rodomanova

“…Unsatisfactory clinical outcomes and patient dissatisfaction with the functional and aesthetic results of treating a mallet finger remain a significant challenge, as there is a lack of consensus among specialists regarding the optimal treatment approach, depending on the specific injury type. …”
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Targeting NADPH oxidase-driven oxidative stress in diabetic cardiomyopathy: mechanisms and therapeutic perspectives by Zilv Ye, Zilv Ye, Sutong Wang, Zhengdong Wan, Birun Huang, Jiawei Guo, Jiawei Guo

“…Diabetic cardiomyopathy (DCM) is a major complication of diabetes mellitus, characterized by microvascular dysfunction and progressive structural and functional deterioration of the heart. A central driver of DCM pathogenesis is chronic oxidative stress (OS), primarily resulting from excessive production of reactive oxygen species (ROS) under hyperglycemic conditions. …”
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Cold ischemia during laparoscopic partial nephrectomy for a complex tumor (RENAL SCORE-11): a clinical case in one institute by M. Y. Gaas, A. D. Kaprin, N. V. Vorobyev, R. O. Inozemtsev, A. G. Rerberg

“…Background. Depending on the stage or location of the tumor, kidney resection or nephrectomy is the gold standard of treatment for renal cell carcinoma Preservation of organ function is essential for patients with localized tumors, especially with one kidney, chronic kidney disease, proteinuria, or multiple/bilateral masses. …”
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Injury-specific pathways shape corneal nerve regeneration dynamics by Léna Meneux, Sarah Pernot, Nadège Feret, Melissa Girard, Alicia Caballero Megido, Marilou Decoudu, Naima Nhiri, Elea Miessen, Eric Jacquet, Vincent Daien, Frederic Michon

“…We found that the type of injury distinctly influences both the structural and functional recovery of corneal nerves. Axotomy resulted in delayed nerve regeneration, significant disruption of epithelial cell homeostasis, and increased risk of severe corneal damage. …”
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DNA Damage-Induced Ferroptosis: A Boolean Model Regulating p53 and Non-Coding RNAs in Drug Resistance by Shantanu Gupta, Daner A. Silveira, José Carlos M. Mombach, Ronaldo F. Hashimoto

“…Post-translational modifications of p53 generate proteoforms that significantly enhance its functional diversity in regulating these mechanisms. …”
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Licochalcone A suppresses pancreatic ductal adenocarcinoma progression by targeting eEF2K-mediated pyroptosis by Junjie Peng, Hiutung Chan, Wenqing Chen, Ken Kin-Lam Yung, King-Ho Cheung, Zhu Zhang

“…Collectively, these findings identify LHA as a dual-function agent: a natural eEF2K inhibitor and a pyroptosis inducer with potent antitumor activity against PDAC. …”
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Long-term effectiveness and safety of methotrexate-tacrolimus combination therapy versus methotrexate monotherapy in reducing rheumatoid arthritis flares after TNF inhibitor discon... by Taio Naniwa, Mikiko Kajiura

“…Per-observation time-to-event analyses assessed treatment failure, treatment intensification, first disease flare, and irreversible functional deterioration. Mixed-effects Cox models, time-dependent Cox models without random effects, and Kaplan-Meier estimates with inverse probability weighting were applied. …”
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ROLE OF CXCR3 CHEMOKINE RECEPTOR AND ITS LIGANDS IN CERTAIN DISEASES by N. A. Arsentieva, A. V. Semenov, D. A. Zhebrun, E. V. Vasilyeva, Areg A. Totolian

“…Chemokines are a special family of cytokines whose main function is to control cell migration; they are key players in the innate and adaptive immune responses. …”
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Diabetes Differentially Affects Vascular Reactivity in Isolated Human Arterial and Venous Bypass Grafts by Aylin Vidin Şen, Birsel Sönmez Uydeş Doğan, Uğur Kısa, Cevdet Uğur Koçoğulları, Önder Teskin, Fatoş İlkay Alp Yıldırım

“…This study aimed to elucidate the functional characteristics of human bypass grafts for the internal mammary artery (IMA) and saphenous vein (SV), from both diabetic and non-diabetic patients, and to determine how diabetes affected their responses to spasmogenic and relaxant agents. …”
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Targeting LAT1 with JPH203 to reduce TNBC proliferation and reshape suppressive immune microenvironment by blocking essential amino acid uptake by Yajie Zhao, Chunrui Pu, Kangdong Liu, Zhenzhen Liu

“…However, the distribution and functional roles of these transporters across breast cancer subtypes have not been fully elucidated. …”
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Intestinal Microbiota in Patients with Chronic Heart Failure and Systolic Dysfunction by M. V. Fadeeva, A. V. Kudryavtseva, G. S. Krasnov, M. R. Skhirtladze, V. T. Ivashkin

“…At the family level, an increase in the proportion of Methanobacteriaceae (p = 0.03) and a decrease in the proportion of Pseudomonadaceae (p = 0.01) and Moraxellaceae (p = 0.01) were noted. No dependence of the intestinal microflora composition on the functional class of heart failure was observed. …”
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Elucidating the mechanism of triphenyl phosphate interference in bone metabolism via network toxicology and molecular docking methodologies by Min Xu, Yinxiang Wu, Jiaqi Meng, Mengchen Chen, Chen Ding

“…GO and KEGG analyses indicated that these targets predominantly function through the MAPK signaling pathway. Molecular docking results demonstrated strong binding affinities between TPhP and key targets, particularly BRAF and WNK4. …”
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The evolution of three generations of platelet concentrates products: a leap from classical formulations to the era of extracellular vesicles by Youan Li, Huimin You, Chunhui Ou, Hongyuan Zhu, Biao Cheng, Ju Tian

“…This review analyzes three generations of PCs products, comparing their technological progress, functional differences, and clinical applications. It proposes a novel function-driven classification system that redefines PCs generations based on biological activity rather than chronological development. …”
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Features of localization, frequency of occurrence and combination of endometrioid lesions in recurrent external genital endometriosis by F. T. Aliyeva, D. V. Bryunin

“…All patients underwent clinical, functional, endoscopic, immunological and morphological methods of examination. …”
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Application of PVA hydrogel loaded with luteolin nanoparticles in anti EMT treatment after GBM by Long Zhou, Qingyu Zhao, Lijuan Gu, Renfu Tian, Yong Li, Xiaoxing Xiong

“…We discovered that the observed anti-tumor effects of LU NPs were dependent on the function of β-catenin. Additionally, we successfully constructed a PVA hydrogel loaded with LU NPs (LU@gel). …”
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Transferable approaches to CRISPR-Cas9 induced genome editing in non-model insects: a brief guide by Hassan M. M. Ahmed, Lisha Zheng, Vera S. Hunnekuhl

“…Abstract Despite the large variety of insect species with divergent morphological, developmental and physiological features questions on gene function could for a long time only be addressed in few model species. …”
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