Milk-derived bioactive peptides by Phareichon Kashung, Devi Karuthapandian

“…Abstract Bioactive peptides are the functional concept that refer to fragments of proteins that provide both functional and nutritional benefits as a functional component. …”
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Investigation of quantum trajectories in photosynthetic light harvesting through a quantum stochastic approach by Teerapat Uthailiang, Ongart Suntijitrungruang, Purin Issarakul, Peera Pongkitiwanichakul, S. Boonchui

“…Our method is to analyze exciton transfer dynamics through paths on the Bloch sphere, in order to investigate the propagating states in accordance with the weight functional which depends on the coupling parameter between the system and environment as the phonon bath. …”
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On-demand imidazolidinyl urea-based tissue-like, self-healable, and antibacterial hydrogels for infectious wound care by Qi Wu, Krishanu Ghosal, Nadine Kana'an, Shounak Roy, Nagham Rashed, Ranabir Majumder, Mahitosh Mandal, Liang Gao, Shady Farah

“…Molecular dynamics (MD) simulation and density functional theory (DFT) calculation were employed to well-understand the extent of H-bonding and metal-ligand coordination to finetune hydrogels’ properties. …”
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Abstract 129: Endovascular Therapy in Cerebral Venous Thrombosis: Nationwide Insights and Implications for Mortality by Liqi Shu, Elizabeth M. Lee, Piers Klein, Mohamad Abdalkader, Thanh Nguyen, Shadi Yaghi, Thalia Field, Lily Zhou

“…Introduction Cerebral Venous Thrombosis (CVT) is a rare cerebrovascular condition causing death or functional dependency in 10‐15%. Although Endovascular Therapy (EVT) is deployed variably across centers for managing CVT, the determinants and consequences of such use remain under‐explored. …”
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Embryonic macrophages orchestrate niche cell homeostasis for the establishment of the definitive hematopoietic stem cell pool by Gülce Perçin, Konstantin Riege, Julia Fröbel, Jonas Metz, Stephan Culemann, Mathias Lesche, Susanne Reinhardt, Thomas Höfer, Steve Hoffmann, Claudia Waskow

“…Presence of embryonic macrophages in the bone marrow and functional impact on hematopoietic stem cells (HSC) or the niche remains unclear. …”
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A combination of four Toxoplasma gondii nuclear-targeted effectors protects against interferon gamma-driven human host cell death by Brittany Henry, Aubrey J. Phillips, L. David Sibley, Alex Rosenberg

“…However, these screens did not pinpoint specific MYR-dependent GRA proteins responsible for IFNγ signaling blockade, suggesting potential functional redundancy. …”
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3D variability analysis reveals a hidden conformational change controlling ammonia transport in human asparagine synthetase by Adriana Coricello, Alanya J. Nardone, Antonio Lupia, Carmen Gratteri, Matthijn Vos, Vincent Chaptal, Stefano Alcaro, Wen Zhu, Yuichiro Takagi, Nigel G. J. Richards

“…Abstract Advances in X-ray crystallography and cryogenic electron microscopy (cryo-EM) offer the promise of elucidating functionally relevant conformational changes that are not easily studied by other biophysical methods. …”
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Unveiling complex brain dynamics during movie viewing via deep recurrent autoencoder model by Kexin Wang, Limei Song, Zhaowei Li, Liting Wang, Xiaowei He, Yudan Ren, Jinglei Lv

“…In this study, we introduced an unsupervised deep recurrent autoencoder (DRAE) model combined with a sliding window approach, effectively capturing the brain's long-term temporal dependencies, as measured in functional magnetic resonance imaging (fMRI), when subjects viewing a long-duration and emotional film. …”
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IGSF11: A Novel Target for Cancer Immunotherapy by Zhibo FENG, Xiyang TANG, Yao LV, Zhaoxiang WANG, Zhixiang ZHANG, Longyan NIE, Shaohui RU, Jinbo ZHAO

“…Through the IGSF11/VISTA axis, it suppresses T cell function and represents a promising novel target for cancer immunotherapy. …”
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The impact of PCR duplication on RNAseq data generated using NovaSeq 6000, NovaSeq X, AVITI, and G4 sequencers by Natalia Zajac, Ioannis S. Vlachos, Sija Sajibu, Lennart Opitz, Shuoshuo Wang, Sridar V. Chittur, Christopher E. Mason, Kevin L. Knudtson, John M. Ashton, Hubert Rehrauer, Catharine Aquino

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Impact of Legacy Perfluorooctane Sulfonate (PFOS) and Perfluorooctanoate (PFOA) on GABA Receptor-Mediated Currents in Neuron-Like Neuroblastoma Cells: Insights into Neurotoxic Mech... by Laura Lagostena, Davide Rotondo, Davide Gualandris, Antonio Calisi, Candida Lorusso, Valeria Magnelli, Francesco Dondero

“…Despite regulatory restrictions, their pervasive nature necessitates further research into their potential effects on cellular and neuronal function. This study first evaluated the cytotoxic effects of PFOS and PFOA on S1 neuroblastoma cells; a dose-dependent reduction in cell viability was revealed for PFOS, while PFOA exhibited minimal toxicity until millimolar concentrations. …”
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Causes and consequences of material variation in avian nest building by Shoko Sugasawa, Mike Hansell, Maggie Reilly, Susan D. Healy

“…Warblers appear to be able to build equally functional nests using whatever materials are readily available in respective habitats. …”
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Synergistic mechanisms of DGAT and PDAT in shaping triacylglycerol diversity: evolutionary insights and metabolic engineering strategies by Wen-Lu Cai, Wen-Lu Cai, Shui-Yan Yu, Yong-Hong Hu

“…By integrating functional studies, evolutionary analyses, and lipidomic data, we reveal the distinct substrate preferences of DGAT and PDAT, their differential contributions to TAG synthesis, and their synergistic mechanisms in shaping triacylglycerol diversity. …”
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Microparticles That Form Immune Complexes as Modulatory Structures in Autoimmune Responses by Catalina Burbano, Mauricio Rojas, Gloria Vásquez, Diana Castaño

“…Initially MPs were considered to be inert cellular products with no biological function. However, an extensive research and functional characterization have shown that the molecular composition and the effects of MPs depend upon the cellular background and the mechanism inducing them. …”
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TRIM25 facilitates ferroptosis in ovarian cancer through promoting PIEZO1 K63-linked ubiquitination and degradation by Ya Li, Fei Zhou, Zhengmei Xu

“…Methods: The role of TRIM25 in ovarian cancer was examined through functional gain- and loss-of-function assays both in vitro and in vivo, while its target genes were identified. …”
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Directed Fusion of Mesenchymal Stem Cells with Cardiomyocytes via VSV-G Facilitates Stem Cell Programming by Nicholas A. Kouris, Jeremy A. Schaefer, Masato Hatta, Brian T. Freeman, Timothy J. Kamp, Yoshihiro Kawaoka, Brenda M. Ogle

“…Mesenchymal stem cells (MSCs) spontaneously fuse with somatic cells in vivo, albeit rarely, and the fusion products are capable of tissue-specific function (mature trait) or proliferation (immature trait), depending on the microenvironment. …”
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The Effects of Preparation Period on Motor Skills of Wheelchair Basketball Players: A Pilot Study by Goran Kozomara, Petar Petrovic, Goran Nikolic, Bojan Jorgic, Miodrag Kocic, Marko Aleksandrovic

“…Future studies should estimate the impact of similar training on the motor skills of wheelchair basketball players, on a larger sample and in the function of injuries, impairment and functional classes of players.…”
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Cholesterol modulates membrane elasticity via unified biophysical laws by Teshani Kumarage, Sudipta Gupta, Nicholas B. Morris, Fathima T. Doole, Haden L. Scott, Laura-Roxana Stingaciu, Sai Venkatesh Pingali, John Katsaras, George Khelashvili, Milka Doktorova, Michael F. Brown, Rana Ashkar

“…Our observations reveal that compositional complexity can be explained by simple biophysical laws that directly map membrane elasticity to molecular packing associated with biological function, curvature transformations, and protein interactions. …”
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Bacterial Meningoencephalitis in Newborns by Alessia Guarnera, Giulia Moltoni, Francesco Dellepiane, Giulia Lucignani, Maria Camilla Rossi-Espagnet, Francesca Campi, Cinzia Auriti, Daniela Longo

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Sensory Encoding Alternates With Hippocampal Ripples across Cycles of Forebrain Spiking Cascades by Yifan Yang, David A. Leopold, Jeff H. Duyn, Grayson O. Sipe, Xiao Liu

“…It is hypothesized that the infra‐slow cascade dynamics reflect an adaptive cycle of alternating exteroceptive sensory sampling and internal mnemonic function that persistently pervades the forebrain, only stopping during active exploration of the environment.…”
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