Ferroptosis in Cancer: Epigenetic Control and Therapeutic Opportunities by Roberta Veglia Tranchese, Sabrina Battista, Laura Cerchia, Monica Fedele

“…Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has emerged as a critical pathway in cancer biology. …”
Get full text

Exploring the Relationship between Spatiotemporal Distribution of Urban Vibrancy and Neighborhood Attributes by Coupling Multi-Source Data: A Case of Nanshan District in Shenzhen by Liu Feng, Tang Zhong, Zhang Liang, Yu Lingmin, Liu Ke

“…The effects of greenness, openness, business function, traffic function, residence function, and living function variate depends on space changes as well as the inhibiting effects of casual function; 3) Neighborhood with compact buildings, composite functions, and green surroundings motivate the surge of urban vibrancy; therefore, the creation of spaces with mixed functionality and compact structure, routes with diverse street view interface elements and open sky views, places with multi-level and highly accessible blue-green landscapes, and cultivation of new urban functions through urban renewal are encouraged during urban construction. …”
Get full text

The separatrix electron density in JET, ASDEX upgrade and alcator C-Mod H-mode plasmas: A common evaluation procedure and correlation with engineering parameters by D. Silvagni, O. Grover, A. Stagni, J.W. Hughes, M.A. Miller, B. Lomanowski, G. Ciraolo, M. Dunne, T. Eich, L. Frassinetti, C. Giroud, I. Jepu, A. Kallenbach, A. Kirjasuo, A. Kuang, T. Luda, C. Perez von Thun, T. Pütterich, H.J. Sun, H. Zohm

“…This quantity has been measured in H-mode discharges on JET, ASDEX Upgrade and Alcator C-Mod by applying the same fitting function to Thomson scattering measurements, and by employing the same analysis technique based on scrape-off layer power balance. …”
Get full text

The GAGA factor regulatory network: Identification of GAGA factor associated proteins. by Dmitry Lomaev, Anna Mikhailova, Maksim Erokhin, Alexander V Shaposhnikov, James J Moresco, Tatiana Blokhina, Daniel Wolle, Tsutomu Aoki, Vladimir Ryabykh, John R Yates, Yulii V Shidlovskii, Pavel Georgiev, Paul Schedl, Darya Chetverina

“…Consistent with this hypothesis the GAF interacting network includes a large collection of factors and complexes that have been implicated in many different aspects of gene activity, chromosome structure and function. Moreover, we show that GAF interactions with a small subset of partners is direct; however for many others the interactions could be indirect, and depend upon intermediates that serve to diversify the functional capabilities of the GAF protein.…”
Get full text

Mast cells in lung of rat by I. Ivanova

“…Many authors from the 19th century to the present day have traced and described the role of mast cells in the human body, their structure and changes depending on the functional state of the organism. …”
Get full text

Vacancy Defect Reconstruction and its Effect on Electron Transport in Si-C Nanotubes by S. Choudhary, S. Qureshi

“…We investigate the vacancy defect reconstruction and its effect on I-V characteristics in a (4, 0) zigzag and (5, 5) armchair silicon-carbide nanotubes (SiCNTs) by applying self consistent non-equilibrium Green’s function formalism in combination with the density-functional theory to a two probe molecular junction constructed from SiCNTs. …”
Get full text

ANTHOCYANIN AS NATURAL COLORANT: A REVIEW by Winda Nurtiana

“…Today, natural colorant is consumer’s selection because it has functional function. One of natural colorant is anthocyanin. …”
Get full text

Robust H∞ Control for Nonlinear Uncertain Switched Descriptor Systems with Time Delay and Nonlinear Input: A Sliding Mode Approach by Mourad Kchaou, Saleh Al Ahmadi

“…Moreover, based on a new Lyapunov-Krasovskii functional, a delay-dependent sufficient condition is established such that the admissibility as well as the H∞ performance requirement of the sliding mode dynamics can be guaranteed in the presence of time delay, external disturbances, and nonlinear input which comprises dead-zones and/or sector nonlinearities. …”
Get full text

Influence of pyrolytic temperature on uranium adsorption capability by biochar derived from macauba coconut residue by Sabine Neusatz Guilhen

“…Because of its porous structure, charged surface and surface functional groups, BC exhibits a great potential as an adsorbent.  …”
Get full text

Rossby Number Regime, Convection Suppression, and Dynamo-generated Magnetism in Inflated Hot Jupiters by Albert Elias-López, Matteo Cantiello, Daniele Viganò, Fabio Del Sordo, Simranpreet Kaur, Clàudia Soriano-Guerrero

“…Specifically, we obtain the Rossby number Ro as a function of planetary depth and orbital period, after showing that tidal synchronization is likely valid for all HJs. …”
Get full text

Risk Factors Promoting Early Cardiovascular Structure Disorders in Patients with Primary Hypothyroidism by A. V. Nikolaeva, L. T. Pimenov, V. G. Sufiyanov, M. V. Dudarev

“…To develop the pattern of early cardiovascular disorders in patients with primary hypothyroidism based on the analysis of relationship between patient’s thyroid status and some functional cardiovascular parameters depending on compensation status. …”
Get full text

Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover. by Konstantinos J Mavrakis, Rebecca L Andrew, Kian Leong Lee, Chariklia Petropoulou, James E Dixon, Naveenan Navaratnam, Dominic P Norris, Vasso Episkopou

“…We have shown that Arkadia, a nuclear RING-domain E3 ubiquitin ligase, is essential for a subset of Nodal functions in the embryo, but the molecular mechanism of its action in embryonic cells had not been addressed. …”
Get full text

Acute hyperglycaemia leads to altered frontal lobe brain activity and reduced working memory in type 2 diabetes. by Anna Backeström, Konstantin Papadopoulos, Sture Eriksson, Tommy Olsson, Micael Andersson, Kaj Blennow, Henrik Zetterberg, Lars Nyberg, Olov Rolandsson

“…Twenty-two of the participants (10 cases, 12 controls, mean age 69 years) were randomly invited to undergo the same clamp procedures to challenge working memory, using 1-, 2-, and 3-back, while monitoring brain activity by blood oxygen level-dependent functional magnetic resonance imaging (fMRI). …”
Get full text

The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications by Monika Kamińska, Maria Jasiewicz, Magdalena Miernik-Skrzypczak, Aleksandra Spyra, Marta Malicka, Natalia Dąbrowska, Aleksandra Kozioł, Katarzyna Moczyróg

“…For type 1 diabetes, MSCs reduced inflammation, preserved pancreatic islet function, and decreased insulin requirements without major adverse effects. …”
Get full text

Therapeutic effects and mechanisms of Xinmaitong formula for type 2 diabetes mellitus via GLP-1R signaling by Weidong Pu, Weidong Pu, Weidong Pu, Yang Pan, Yang Pan, Yang Pan, Kang Yang, Kang Yang, Kang Yang, Jian Gao, Jian Gao, Jian Gao, Fen Tian, Fen Tian, Fen Tian, Jingrui Song, Jingrui Song, Yubing Huang, Yubing Huang, Yanmei Li, Yanmei Li, Yanmei Li

“…The Xinmaitong formula (XMT) is a folk remedy believed to lower blood lipid levels. However, the functional components and molecular mechanisms through which XMT exerts its anti-diabetic effects remain to be elucidated. …”
Get full text

Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62 by Kirk A. Taylor, Amro Elgheznawy, Recep Adiyaman, Tyler L. Horn, Sarah Parkes, Craig E. Hughes, Liam J. McGuffin, Jonathan M. Gibbins

“… Connexin (Cx) gap junction proteins are expressed by a multitude of cells and function as plasma membrane hemichannels or dock to form intercellular communication tunnels. …”
Get full text

Few-shot object detection for pest insects via features aggregation and contrastive learning by Shuqian He, Shuqian He, Biao Jin, Biao Jin, Xuechao Sun, Wenjuan Jiang, Wenjuan Jiang, Jiaxing Gu, Fenglin Gu

“…To manage class imbalance and enhance the focus on challenging samples, focal loss and class weights are integrated into the model’s comprehensive loss function. Experimental validation on the PestDet20 dataset, consisting of diverse tropical pest insects, demonstrates that the proposed method significantly outperforms existing approaches, including YOLO, TFA, VFA, and FSCE. …”
Get full text

Enhancing the nutritional profile of African sharptooth catfish (Clarias gariepinus) through dietary supplementation with natural minerals and probiotic Escherichia coli 39-SN by Nurzhan Sarsembayeva, Gulmariya Ikramzhan, Tolkyn Abdigaliyeva, Zhumagul Kirkimbaeva, Birzhan Biyashev, Saule Sherimova, Primkul Ibragimov

“…Background and Aim: Feed additives composed of natural minerals and probiotics are increasingly explored in aquaculture to improve fish health and meat quality while reducing antibiotic dependency. Zeolite and vermiculite, due to their adsorptive and ion-exchange properties, enhance mineral bioavailability, whereas probiotics, such as Escherichia coli 39-SN improve digestive function and nutrient assimilation. …”
Get full text

Geospatial analysis of soil property variability in cyclone-affected areas of southern Malawi by Jabulani Nyengere, Innocent Gomani, Isaac Tchuwa, Wilfred Kadewa, Agnes Mercy Hamisi, Chikondi Chisenga, Emmanuel Chinkaka, Weston Mwase, Precious Masuku, Harineck Tholo

“…This knowledge gap hinders our ability to predict long-term impacts on soil quality and ecosystem function, underscoring the need for further research. …”
Get full text

Patients’ and Health Care Professionals’ Expectations of Virtual Therapeutic Agents in Outpatient Aftercare: Qualitative Survey Study by Diana Immel, Bernhard Hilpert, Patricia Schwarz, Andreas Hein, Patrick Gebhard, Simon Barton, René Hurlemann

“…A biofeedback function was desired to detect early warning signs of disease. …”
Get full text