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  1. 521

    Adverse childhood experiences impair cognitive function via social isolation and functional limitations in Chinese middle-aged and older adults by Yan Zhu, Haojie Yin, Xianli Zhong, Li Wang, Xiaobin Tang, Qin Zhang, Ping Jia

    Published 2025-07-01
    “…Mplus 8.0 software was used to construct a structural equation model with ACEs as the independent variable, cognitive function as the dependent variable, and social isolation and functional limitations as mediating variables. …”
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    Article
  2. 522

    Effects of acute sleep deprivation on the brain function of individuals with migraine: a resting-state functional magnetic resonance imaging study by Shuqing Wang, Longteng Ma, Song Wang, Caohui Duan, Xinyu Wang, Xiangbing Bian, Deqi Zhai, Yin Sun, Siyuan Xie, Shuhua Zhang, Yingyuan Liu, Xiaoxue Lin, Ruobing Wang, Xiu Liu, Shengyuan Yu, Xin Lou, Zhao Dong

    Published 2025-03-01
    “…The aim of this study was to investigate the effects of acute sleep deprivation (ASD) on brain function in individuals with migraine without aura (MWoA) via functional magnetic resonance imaging (fMRI). …”
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    Study of cytostatic and cytotoxic characteristics of modified peptide CDK4/6 inhibitors – functional analogs of p16INK4a (90-97) by V. K. Bozhenko, T. M. Kulinich, E. A. Kudinova, A. V. Ivanov, A. M. Shishkin, V. A. Solodkiy

    Published 2021-01-01
    “…Application of mathematical modeling for search and development of functionally active molecules allowed to create peptide sequences with stronger cyclin-dependent kinase inhibitor effect than p16INK4a, the native inhibitor CDK4/6.…”
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    hUMSC-Exosomes suppress TREM1-p38 MAPK signaling via HMGB1-dependent mechanisms to reprogram microglial function and promote neuroprotection in ischemic stroke by Zengyu Zhang, Rong Ji, Zhuohang Liu, Zhiwen Jiang, Min Chu, Yong Wang, Jing Zhao

    Published 2025-08-01
    “…By delivering HMGB1, hUMSC-Exos inhibit TREM1-dependent NF-κB/p38 activation, reprogram microglial function, and confer neuroprotection. …”
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    Article
  13. 533

    <i>Lactobacillus rhamnosus</i> GG Modulates Mitochondrial Function and Antioxidant Responses in an Ethanol-Exposed In Vivo Model: Evidence of HIGD2A-Dependent OXPHOS Remodeling in the Liver by Celia Salazar, Marlen Barreto, Alfredo Alfonso Adriasola-Carrasco, Francisca Carvajal, José Manuel Lerma-Cabrera, Lina María Ruiz

    Published 2025-05-01
    “…The gut microbiota plays a central role in host energy metabolism and the development of metabolic disorders, partly through its influence on mitochondrial function. Probiotic supplementation, particularly with <i>Lactobacillus rhamnosus</i> GG, has been proposed as a strategy to modulate the microbiota and improve host metabolic health. …”
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  15. 535

    Effect of Acupuncture on Functional Connectivity of the Limbic Network in Patients with Knee Osteoarthritis: A Resting State Functional Magnetic Resonance Imaging Study by Wu N, Lou XS, Chang YN, Li JY, Zhang ZH, Hu JH, Fan Y, Feng XD, Yin S

    Published 2025-07-01
    “…This study investigated brain network differences between KOA patients and healthy controls and further examined the effects of acupuncture on aberrant functional connectivity (FC) within brain networks in KOA patients.Patients and Methods: Blood Oxygenation Level Dependent functional Magnetic Resonance Imaging (BOLD-fMRI) combined with Independent Component Analysis (ICA) was employed to investigate resting-state functional connectivity differences between 45 KOA patients and 15 healthy subjects. …”
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  18. 538

    Elderly with ischemic stroke: social-demographic and functional characterization by Chrystiany Plácido de Brito Vieira, Ana Virgínia de Melo Fialho, Paulo César de Almeida, Thereza Maria Magalhães Moreira

    Published 2012-06-01
    “…The proportion of elderly was uniformly distributed in the range of disability and dependency (p=0.972 and p=0.780). The knowledge of the profile of the elderly is crucial because their quality of life has a strong connection with their social and economic reality, as well as with their functional capacity.…”
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  19. 539

    THE REPRODUCTIVE FUNCTION OF WOMEN AFTER DESTRUCTIVE OPERATIONS ON THE CERVIX by F. F. Badretdinova, V. V. Kortunova

    Published 2016-06-01
    “…Nearly one-third of pregnancies in women major group (29 women) has ended medical abortion After conization of cervix regardless of how the pregnancy was significantly more complicated by her amnion protrudes like a threat of termination, at different gestational ages. destructive interference in the cervix a little (statistically unreliable p≥0.05) affect the course of pregnancy, however, there is a dependency on the reproductive function of the type and depth of destructive interference.…”
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