Automated assembly of molecular mechanisms at scale from text mining and curated databases by John A Bachman, Benjamin M Gyori, Peter K Sorger

“…Abstract The analysis of omic data depends on machine‐readable information about protein interactions, modifications, and activities as found in protein interaction networks, databases of post‐translational modifications, and curated models of gene and protein function. …”
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Treadmill training as an augmentation treatment for Alzheimer?s disease: a pilot randomized controlled study by Cynthia Arcoverde, Andrea Deslandes, Helena Moraes, Cloyra Almeida, Narahyana Bom de Araujo, Paulo Eduardo Vasques, Heitor Silveira, Jerson Laks

“…Compared to the CG, the EG presented significant improvement on the functional capacity. The analysis of the effect size has shown a favorable response to the physical exercise in all dependent variables. …”
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Study of the temperature conditions of power transformers elements for example transformers at substation «Kabun-І» (Syrian Arab Republic) by E. I. Gracheva, A. A. Alzakkar, S. Valtchev

“…Determination of the type of functional dependences of the heating temperature of windings and oil ofpower transformers on their loading. …”
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Case Report: Case study of 100 consecutive IRONMAN®-distance triathlons—impact of race splits and sleep on the performance of an elite athlete by Beat Knechtle, Beat Knechtle, Luciano Bernardes Leite, Luciano Bernardes Leite, Pedro Forte, Pedro Forte, Pedro Forte, Pedro Forte, Marilia Santos Andrade, Ivan Cuk, Pantelis T. Nikolaidis, Volker Scheer, Katja Weiss, Thomas Rosemann

“…To date, this is the longest self-paced world record attempt for most daily IRONMAN®-distance triathlons.MethodsTo assess the influence of each activity's duration on the total time, the cross-correlation function was calculated for swimming, cycling, running, and sleeping times. …”
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Plasticity of Adult Sensorimotor System in Severe Brain Infarcts: Challenges and Opportunities by Annette Sterr, Adriana Bastos Conforto

“…Functional reorganization forms the critical mechanism for the recovery of function after brain damage. …”
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Conversion from SMOFlipid® to Omegaven® as a salvage therapy for intestinal failure associated liver disease by Stella Sabbatini, Fernanda Takamatsu, Christina Belza, Glenda Courtney-Martin, Daniela Gattini, Yaron Avitzur

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MALNUTRITION AT HOSPITAL ADMISSION AND ITS ASSOCIATED FACTORS IN INTERNAL MEDICINE INPATIENTS by Wita Rizki Amelia, Astrine Permata Leoni, Ahmad Syauqy, Purwita Wijaya Laksmi, Martalena Br Purba, Etika Ratna Noer, Lora Sri Nofi, Befi Sundari, Mita Arini

“…In addition, subjects with a severe to total dependency on functional status (OR 9.406, 95%CI: 3.147–28.109), inadequate energy intake (OR 2.718, 95%CI: 1.197–6.172), and multimorbidity (OR 2.337, 95%CI: 1.045–5.228), were significantly associated with malnutrition at hospital admission cases. …”
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Hardcoded vulnerability detection approach for IoT device firmware by Chao MU, Xin WANG, Ming YANG, Heng ZHANG, Zhenya CHEN, Xiaoming WU

“…With the popularization of IoT devices, more and more valuable data is generated.Analyzing and mining big data based on IoT devices has become a hot topic in the academic and industrial circles in recent years.However, due to the lack of necessary detection and protection methods, many IoT devices have serious information security risks.In particular, device hard-coded information is closely related to system encryption and decryption, identity authentication and other functions, which can provide confidentiality protection for core data.Once this information is exploited by malicious attackers, serious consequences such as sensitive information leakage, backdoor attacks, and unauthorized logins will occur.In response to this problem, a multi-type character recognition and positioning scheme was designed and a hard-coded vulnerability detection method in executable files was proposed based on the study of the characteristics of hard-coded vulnerabilities in IoT devices.The proposed method extracted the firmware of IoT devices and filtered all executable files as the source to be analyzed.Then, a solution to identify and locate three types of hard-coded characters was provided.Further, the reachability of the function, where the hard-coded character was located, was analyzed according to the function call relationship.Meanwhile, the instruction heterogeneity was mitigated by an intermediate representation (IR) model.The character and parameter hard-coded values was obtained through a data flow analysis approach.A symbolic execution method was devised to determine the trigger conditions of the hard-coded vulnerabilities, and then the vulnerability detection result was output.On the one hand, the proposed method introduced the method of symbolic execution based on the use of the intermediate representation model, which eliminated the dependency of instruction architecture and reduces the false positive rate of vulnerabilities; On the other hand, this method can integrate characters, files, and cryptographic implementation to realize the different characteristics of three types of hard-coded characters, which increased the coverage of vulnerability detection and improves the versatility of the detection method.The experimental results show that the proposed method can effectively detect three types of hard-coded vulnerabilities of characters, files and cryptographic implementation in various IoT devices, and has good detection accuracy, which can provide certain guidance for the deployment of subsequent security protection technologies.…”
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Global siRNA screen identifies human host factors critical for SARS-CoV-2 replication and late stages of infection. by Xin Yin, Yuan Pu, Shuofeng Yuan, Lars Pache, Christopher Churas, Stuart Weston, Laura Riva, Lacy M Simons, William J Cisneros, Thomas Clausen, Grace Biddle, Simon Doss-Gollin, Meagan Deming, Paul D De Jesus, Ha Na Kim, Daniel Fuentes, John M Whitelock, Jeffrey D Esko, Megan S Lord, Ignacio Mena, Adolfo García-Sastre, Judd F Hultquist, Matthew B Frieman, Trey Ideker, Dexter Pratt, Laura Martin-Sancho, Sumit K Chanda

“…Resulting data were integrated with published functional screens and proteomics data to reveal (i) common pathways that were identified in all OMICs datasets-including regulation of Wnt signaling and gap junctions, (ii) pathways uniquely identified in this screen-including NADH oxidation, or (iii) pathways supported by this screen and proteomics data but not published functional screens-including arachionate production and MAPK signaling. …”
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Comprehensive Analysis of Storage Stability of Hong-Jam Under Various Conditions: Correlation Between Lipid Oxidation Factors and Alternative Quality Parameters by Min-Seok Kim, Sang-Jin Ye, Ji-Hwan Roh, Hyun-Wook Choi, Moo-Yeol Baik

“…Hong-Jam is a functional food product made from freeze-dried silkworms on the seventh to eights day of the fifth Instar stage, which are steamed for 2 h prior to drying. …”
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Visible light-driven dearomative meta-cycloadditions of 2-acetonaphthalenes via triplet energy transfer cascade by Pramod Rai, Sanghamitra Naik, Kriti Gupta, Kakoli Maji, Garima Jindal, Biplab Maji

“…The described protocol delivers highly sp3-rich polycyclic frameworks in high yields with wide functional group tolerance. The inclusion of bioactive molecules and the establishment of a wide array of post-synthetic derivatizations further underscores the adaptability of the methodology for generating complex three-dimensional molecules.…”
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MacroD1 sustains mitochondrial integrity and oxidative metabolism by Ann-Katrin Hopp, Lorenza P. Ferretti, Lisa Schlicker, Amalia Ruiz-Serrano, Udo Hetzel, Francesco Prisco, Anja Kipar, Lukas Muskalla, Elena Ferrari, Carsten C. Scholz, Karsten Hiller, Francisco Verdeguer, Deena M. Leslie Pedrioli, Michael O. Hottiger

“…This resulted in increased glucose uptake and dependency both in vitro and in vivo. Hence, our research establishes MacroD1 as a regulator of metabolic homeostasis, which ensures the coordination of cellular carbohydrate flux and optimal mitochondrial function.…”
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Active transportation policy and practice in the city of Oulu from 1998 to 2016—A mixed methods study by Mikko Kärmeniemi, Tiina Lankila, Emilia Rönkkö, Kari Nykänen, Heli Koivumaa-Honkanen, Raija Korpelainen

“…Decreased active transportation mode share might have been due to inadequately assessed functional mix outside the inner city, increased urban sprawl and building more capacity for cars. …”
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Active transportation policy and practice in the city of Oulu from 1998 to 2016—A mixed methods study by Mikko Kärmeniemi, Tiina Lankila, Emilia Rönkkö, Kari Nykänen, Heli Koivumaa-Honkanen, Raija Korpelainen

“…Decreased active transportation mode share might have been due to inadequately assessed functional mix outside the inner city, increased urban sprawl and building more capacity for cars. …”
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Marketing and Innovation Process in Agri-Food Companies: Analysis via the Stage-Gate Model by Hakima SOUKI, Sabrina BOUKELLAL, Mohand CHITI

“…In addition, by mobilising dependency and influence matrices, we situate the place given to marketing in the new product development process while emphasising the importance of cross-functional collaboration. …”
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‘Applied Social Prescribing Practice: A Focused Arts Based Participatory Action Research Study of Military Veteran Transition Into Civilian Life’ by Graham Yitka, Arabella Plouviez, Alison Clelland, Ann Fox, Ger Fowler, John Sargent, Catherine Hayes

“…For those who experience issues in this process of transition, life can often be characterized by perceptions of loneliness, social isolation, poor mental well-being, and a functional dependency on alcohol, alongside other negative behaviors, for coping with post-traumatic stress disorder. …”
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The 15-Minute City: A Paradigm for Urban Planning and Policy by Omid Mobaraki

“…The concept of 15-minute city (FMC) represents an urban planning and policy paradigm that seeks to focus the attention on the neighborhood as a place rather than a spatial and functional planning unit. The main premise of this concept is that urban services and amenities should be accessible within 15 minutes of walking or cycling from the residence. …”
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Normative data of ultrasound quadriceps rectus femoris geometric values. The ECOSARC-2 Study by Ester López Jiménez, Paola Reinoso Párraga, Alfonso González Ramírez, Marta Neira Álvarez, Adriana Abizanda Saro, Marisa Fernández González de la Riva, Cristina Alonso Bouzón, Victoriano Chavero Carrasco, Gema Montemayor Galán, Juan Rodríguez Solís, Rubén Alcantud Córcoles, Raquel Ramírez Martín, Carmen de Pablos Hernández, Fabricio Zambom-Ferraresi, Brian Dax Vásquez, Pedro Luis Sagüillo González, Ignacio Morón Merchante, Rafael García Molina, Rocío Menéndez Colino, Nicolás Martínez Velilla, Fernando Andrés Pretel, Elena Gómez Jiménez, Marta Sáez Blesa, Elisa Belén Cortés Zamora, Almudena Avendaño Céspedes, Pedro Abizanda

“…Secondary objectives included evaluating the associations between ultrasound measurements and physical function, muscle strength, frailty, and dependency in basic activities of daily living. …”
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The Outcome of COVID-19 Patients with Moderate to Severe Disease: A Single Institution Study by Iffat Rafeeq, Anees Ahmed Gardezi, Nuzhat Rafeeq, Shagufta Parveen, Abeera Ahmad

“…Investigations including complete blood count, serum ferritin, quantitative CRP, liver function tests, renal function tests, blood sugar fasting, and random chest radiographs and ECG were performed. …”
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Broadening Low-Frequency Band Gap of Double-Panel Structure Using Locally Resonant Sonic Crystal Comprised of Slot-Type Helmholtz Resonators by Myong-Jin KIM, Chun-Gil RIM, Kyong-Su WON

“…Finally, the transmission losses (TLs) through the DPS with LRSC are calculated as a function of the incident angle of the sound wave for LRSC embedded in porous material and not. …”
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