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5261
The Constructive Neutral Evolution of Behaviour
Published 2025-07-01“…A probabilistic ‘ratchet’ means this process is more likely to repeat itself than reverse, and hence complexity increases without necessarily any gain in function. Here, we argue that CNE operates not only at the molecular level, but also affects whole organism behaviour. …”
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5262
insilico.mutagenesis: a primer selection tool designed for sequence scanning applications used in directed evolution experiments
Published 2005-11-01“…We report a novel primer prediction tool (insilico.mutagenesis), accessible at www.insilico.uni-duesseldorf.de, developed for the application to high-throughput mutagenesis used in directed evolution or structure-function dependency projects, which involve the subsequent mutagenesis of a large number of amino acid positions (e.g., in whole gene saturation or gene scanning mutagenesis experiments). …”
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5263
Energy Metabolism and Aerobic Respiratory Chain of <i>Vitreoscilla</i> sp. C1: Comparison with β-Proteobacteria
Published 2025-05-01“…C1 features a simplified respiratory chain, experimental data demonstrate that all predicted branches are functional, with two main dehydrogenases and two terminal oxidases.…”
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5264
Kratopenia as an indicator of sarcopenia in smokers: Cut-off points for peak knee torque.
Published 2025-01-01“…A total of 143 smokers were evaluated, with high levels of tobacco dependence and preserved lung function. Men showed significantly higher peripheral muscle strength across all variables (p < 0.05). …”
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5265
Cofilin1 controls transcolumnar plasticity in dendritic spines in adult barrel cortex.
Published 2015-02-01“…During sensory deprivation, the barrel cortex undergoes expansion of a functional column representing spared inputs (spared column), into the neighboring deprived columns (representing deprived inputs) which are in turn shrunk. …”
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5266
Palliative sedation at the end of life: prevalence, characteristics and possible determinants
Published 2024-12-01“…Methods This was a cross-sectional study including n = 533 patients who died during the study period in a Palliative Care Unit. Clinical and functional (Barthel and Palliative Performance Scale) variables and the level of complexity were collected. …”
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5267
A Systems Hypothesis of Lipopolysaccharide-Induced Vitamin Transport Suppression and Metabolic Reprogramming in Autism Spectrum Disorders: An Open Call for Validation and Therapeut...
Published 2025-06-01“…The model focused on 158 curated metabolic genes selected for their roles in redox balance, mitochondrial function, neurodevelopment, and gut–brain interactions. …”
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5268
Critical Review of Fluid Flow Physics at Micro- to Nano‐scale Porous Media Applications in the Energy Sector
Published 2018-01-01“…Review of fluid flow modeling literature from these applications reveals that further improvements can be made by (i) modeling slip length as a function of key parameters, (ii) coupling the dependency of wettability and slip, (iii) using a reservoir-on-chip approach that can enable capturing the subcontinuum effects contributing to fluid flow in shale reservoirs, and (iv) including Knudsen diffusion and slip in the governing equations of hydrogen gas storage.…”
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5269
Absence of the interthalamic adhesion (ITA) as a neuroanatomical association or risk factor for neuropsychiatric disorders: A systemic review and meta-analysis
Published 2023-10-01“…Owing to the increased interest in the contribution of ITA to neurological function in previous literature, a meta-analysis of its frequency and sex dependency is required. …”
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5270
Case Report: Dual immunomodulatory and hematologic benefits of rituximab in refractory anemia of ANCA-associated vasculitis
Published 2025-08-01“…Early RTX use may reduce transfusion dependency and help stabilize renal function in refractory AAV, though advanced fibrosis limits recovery. …”
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5271
Different Visual Weighting due to Fast or Slow Vestibular Deafferentation: Before and after Schwannoma Surgery
Published 2019-01-01“…Patients that suffered fast loss of remaining vestibular function (group 2) became less visual field dependent after surgery (p≤0.035) and were less able to maintain stability compared with group 1 (p=0.010) and group 3 (p=0.010). …”
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5272
Innovative integration of automated breast volume scan and ultrasound elastography for enhanced differentiation of benign and malignant breast lesions
Published 2025-05-01“…Furthermore, ultrasound elastography (UE) provides complementary functional information by assessing tissue stiffness, aiding in the differentiation between benign and malignant breast lesions. …”
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5273
Threshold and Asymmetric Effects of Foreign Direct Investment on Inclusive Growth in Shanghai Cooperation Member Countries
Published 2025-03-01“…The study calculated and used the inclusive growth variable following the methodology of social welfare function which is also known as the social opportunity function. …”
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5274
QUALITY CONTROL, SAFETY OF RAW MEAT AND TURKEY MEAT PATE AND JUSTIFICATION OF RECIPES AND STERILIZATION REGIMENS
Published 2023-03-01“…Based on the defined function and constraints, we create a spreadsheet in MS Excel according to functional dependency. …”
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5275
Epithelial-mesenchymal transition orchestrates tumor microenvironment: current perceptions and challenges
Published 2025-04-01“…Recent evidence also indicates that cells undergoing EMT may differentiate into cancer-associated fibroblasts, thereby establishing themselves as functional constituents of the TME. Elucidating the relationship between EMT and the TME offers novel perspectives for therapeutic strategies to enhance cancer treatment efficacy. …”
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5276
In Vivo Imaging of Retinoic Acid Receptor Activity using a Sodium/Iodide Symporter and Luciferase Dual Imaging Reporter Gene
Published 2004-07-01“…To visualize the intranuclear responses of functional retinoic acid receptors, we have developed a dual-imaging reporter gene system based on the use of sodium/iodide symporter (NIS) and luciferase in cancer cell lines. …”
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5277
Formation of orthogonal latin squares by index structuring of n-set multiplication tables
Published 2020-10-01“…The use of the method for constructing a family of orthogonal Latin squares for pairs of indexed finite sets of the same odd dimension by the elements forming their multiplication table by the method of index structuring based on the principle of functional dependency of the index values on pairs of set elements and index values on pairs of elements from its environment allows creating a specific class orthogonal configuration, which, in terms of element indices, easily demonstrates their orthogonality.…”
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5278
Integrating published experimental data and hierarchical bayesian modeling: a model for common cuttlefish (Sepia officinalis Linnaeus, 1758) growth to improve predictions for aquac...
Published 2025-12-01“…A mathematical description of sub-adult cephalopod Instantaneous Growth Rate (1–120 days after hatching) was formulated as a multistage function, combining a Gaussian function during the post-hatching stages and an exponential decay function during the transition to the pre-adult stages. …”
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5279
Forecasting Cohesionless Soil Highway Slope Displacement Using Modular Neural Network
Published 2012-01-01“…However, forecasting the failure of highway slop is difficult because of nonlinear time dependency and seasonal effects, which affect the slope displacements. …”
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5280
Attention-CARU With Texture-Temporal Network for Video Depth Estimation
Published 2025-01-01“…Besides, to improve the detection of moving objects in the depth map, an advanced loss function is introduced to further penalise the depth estimation error of moving objects. …”
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