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4961
A map of human cancer signaling
Published 2007-12-01“…One such block, in which the genes are highly mutated and methylated, appears in most tumors and thus plays a central role in cancer signaling. Functional collaborations between two oncogene‐signaling‐dependent blocks occur in most tumors, although breast and lung tumors exhibit more complex collaborative patterns between multiple blocks than other cancer types. …”
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4962
Isolation and characterization of fMGyn-Pae01, a phiKZ-like jumbo phage infecting Pseudomonas aeruginosa
Published 2025-03-01“…Host range screening revealed that fMGyn-Pae01 has a wide host range among P. aeruginosa strains and its infection was not dependent on O-serotype. Whole genome sequencing of the host bacterium and phage resistant mutants revealed that the mutations had inactivated either a flagellar or rpoN gene, thereby preventing the biosynthesis of a functional flagellum. …”
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4963
Sialylated IgG-activated integrin β4-Src-Erk axis stabilizes c-Myc in a p300 lysine acetyltransferase-dependent manner to promote colorectal cancer liver metastasis
Published 2025-03-01“…Materials and methods: Analysis of sialylated IgG in paired tumor tissues and adjacent normal tissues from 65 colorectal cancer patients was performed using immunohistochemical staining. Functional assays of sialylated IgG were explored in vitro and in vivo. …”
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4964
Energy principle application to response of viscoelastic bars
Published 2023-10-01Get full text
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4965
Sodium currents in naïve mouse dorsal root ganglion neurons: No major differences between sexes
Published 2024-12-01“…We recently developed a novel method that enables high-throughput, unbiased, and automated functional analysis of native rodent sensory neurons from naïve WT mice profiled simultaneously under uniform experimental conditions. …”
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4966
High Pressure Restrains the Photo‐Induced Polyhedra Distortion in 0D Antimony‐Based Metal Halide
Published 2025-08-01“…Meanwhile, a single broadband emission peak excited by 355 nm maintains a distinct low energy emission peak throughout the compression process, exhibiting an excitation‐dependent emission color response. Combining experiment results with density functional theory calculations, the observed phenomenon is attributed to pressure restrain of photo‐induced distortion in the [SbCl5]2⁻ polyhedra in (TTA)2SbCl5. …”
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4967
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4968
Leptin and thyroid hormones in beta-thalassemia major: A cross-sectional study
Published 2025-06-01“…This may support the role of leptin on thyroid function in β-TM patients.…”
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4969
Coronary Angioplasty with a Drug-Coated Balloon Catheter in the Treatment of Acute Coronary Syndromes: Medico-Social Perspectives and Challenges of Use in the Setting of Diffuse Co...
Published 2025-06-01“…In addition, DCB has proven effective in treating ISR and preserving endothelial function, with evidence of late lumen enlargement and minimal vascular trauma. …”
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4970
Inhibition of mitophagy via the EIF2S1-ATF4-PRKN pathway contributes to viral encephalitis
Published 2025-07-01“…Conclusion: These results reveal the protective function of mitophagy in HSE pathogenesis and highlight mitophagy activation as a potential antiviral therapeutic strategy for HSV-1-related diseases.…”
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4971
Three-Dimensional Copulas: A Generalized Convex Mixture Copulas Strategy
Published 2024-11-01“…Copulas are multi-dimensional probabilistic functions that play a crucial role in modeling complex dependence structures between random variables. …”
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4973
Postsynaptic spiking determines anti-Hebbian LTD in visual cortex basket cells
Published 2025-02-01Get full text
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4974
Resilience-by-Design in 6G Networks: Literature Review and Novel Enabling Concepts
Published 2024-01-01Get full text
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4975
GRAPHENE OXIDE NANOPARTICLES IN THE REGULATION OF THE OXIDATIVE ACTIVITY OF HUMAN MONOCYTES
Published 2021-10-01“…Thus, we have established for the first time that graphene oxide nanoparticles functionalized with PEG are capable of inhibiting the ROS production by human monocytes, and therefore, we can speak of the antioxidant activity of GO-PEG.…”
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4976
T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade.
Published 2010-12-01“…<h4>Background</h4>Engagement of the β2 integrin, lymphocyte function-associated antigen-1 (LFA-1), results in stabilization of T cell mRNA transcripts containing AU-rich elements (AREs) by inducing rapid nuclear-to-cytosolic translocation of the RNA-stabilizing protein, HuR. …”
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4977
EFFECTIVENESS OF THE MINIMALLY INVASIVE MYOCARDIAL REVASCULARIZATION WITH AORTIC NO-TOUCH TECHNIQUE
Published 2014-09-01“…MIMR strategy was directed to avoid artificial cardiopulmonary bypass with cardioplegia and manipulations on the ascending aorta, usage of the left minithoracotomy access and tendency to perform complete or functionally reasonable arterial myocardium revascularization. 84 patients underwent complete MIMR, 67 patients - functionally reasonable incomplete MIMR. …”
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4978
Optics Temperature-Dependent Nonuniformity Correction Via <inline-formula><tex-math notation="LaTeX"> $\ell _{0}$</tex-math></inline-formula>-Regularized Prior for Airborne Infrare...
Published 2016-01-01“…Based on this effective prior, we present a variational framework where we optimize an energy functional to estimate the optics-related fixed pattern noise (FPN) and the latent image. …”
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4979
ENDOTHELIAL DYSFUNCTION IN ISCHEMIC HEART DISEASE
Published 2016-01-01“…Endothelial vasodilating function was assessed by endothelium-dependent (EDVD) and endothelium-independent vasodilatation (EIDVD) of brachial artery. …”
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4980
MODERN APPROACH TO ASSESS THE ASTHMA CONTROL AND TREATMENT EFFICASY IN DIFFERENT PHENOTYPES BY ENDOTHELIAN DISFUNCTION
Published 2017-03-01“…Conclusions. Change of the functional conditions of the endothelial depend on the time and severity and phenotype of the asthma. …”
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