Therapeutic targeting of the androgen receptor (AR) and AR variants in prostate cancer by Ramesh Narayanan

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Taking into account a location of aircraft’s center of mass during motion cuing by Volodymyr Kabanyachyi, Serhii Hrytsan, Serhii Yankovskyi

“…The problem was solved on the basis of simplified operator for transformation of motion system movements along individual degrees of freedom into jack movements, cubic spline functions to describe the dependence of the centers of rotation along pitch and yaw, and optimization theory using the deformable polyhedron method. …”
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Exploration of soliton solutions of the nonlinear Kraenkel-Manna-Merle system using innovative methods in ferromagnetic materials by Bahadır Kopçasız, Fatma Nur Kaya Sağlam, Homan Emadifar, Karim K. Ahmed

“…The next step, the Kumar-Malik method, and the new extended hyperbolic function method (nEHFM) are used to derive exact soliton solutions of the nonlinear coupled Kraenkel-Manna-Merle system. …”
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Simulation of the hydraulic system of a device with self-adaptation for power and kinematic parameters on the working body by T. A. Khinikadze, A. T. Rybak, P. I. Popikov

“…Therefore, the design and creation of this type of actuators with a self-adaptation function is a critical task.Materials and Methods. …”
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Modeling Pavement Deterioration on Nepal’s National Highways: Integrating Rainfall Factor in a Hazard Analysis by Manish Man Shakya, Kotaro Sasai, Felix Obunguta, Asnake Adraro Angelo, Kiyoyuki Kaito

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Evaluation and analysis of barriers to the innovation activity in the economy of the region by D. A. Tomasova

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Pleiotropic vasoprotective effects of high-dose atorvastatin therapy in the context of achieving the target low-density lipoprotein cholesterol in patients after myocardial infarct... by L. I. Salyamova, A. A. Khromova, O. G. Kvasova, K. N. Korenkova, K. N. Polezhaeva, N. A. Donetskaya, K. I. Pavlenko

“…The results demonstrate the importance of achieving target LDL-C for the most favorable dynamics of brain natriuretic peptide, structural and functional characteristics of the arterial system.…”
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Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria by Mary Lopez-Perez, Zakaria Seidu, Mads Delbo Larsen, Wenjun Wang, Jan Nouta, Manfred Wuhrer, Gestur Vidarsson, Michael F. Ofori, Lars Hviid

“…A similar association was found for children having PfEMP1-specific IgG1 inducing multiple effector functions against IEs, particularly those associated with antibody-dependent cellular cytotoxicity (ADCC) by NK cells. …”
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Motor Improvement of Skilled Forelimb Use Induced by Treatment with Growth Hormone and Rehabilitation Is Dependent on the Onset of the Treatment after Cortical Ablation by Margarita Heredia, Jesús Palomero, Antonio de la Fuente, José María Criado, Javier Yajeya, Jesús Devesa, Pablo Devesa, José Luis Vicente-Villardón, Adelaida S. Riolobos

“…We previously demonstrated that the administration of GH immediately after severe motor cortex injury, in rats, followed by rehabilitation, improved the functionality of the affected limb and reexpressed nestin in the contralateral motor cortex. …”
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DNA-Binding Protein A Is Actively Secreted in a Calcium-and Inflammasome-Dependent Manner and Negatively Influences Tubular Cell Survival by Gregor Hoppstock, Jonathan A. Lindquist, Antonia Willems, Annika Becker, Charlotte Reichardt, Ronnie Morgenroth, Saskia Stolze, Cheng Zhu, Sabine Brandt, Peter R. Mertens

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PRPS2 enhances RNA m6A methylation by stimulating SAM synthesis through enzyme-dependent and independent mechanisms by Lin Zhang, Xian Zhao, Jingyan Hu, Tingting Li, Hong-Zhuan Chen, Ao Zhang, Hao Wang, Jianxiu Yu, Liang Zhang

“…Our study links nucleotide biosynthesis with RNA epigenetics in cancer progression through the PRPS2-MAT2A-WTAP/METTL3/METTL14 axis, and elucidates both enzyme-dependent and independent functions of PRPS2. These findings have significant implications for developing targeted therapies for cancers associated with PRPS2 abnormalities.…”
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Comparison of Efficacy, Safety, and Humanistic Outcomes of Iron-Chelation Therapy in Pediatrics Suffering from Transfusion-Dependent β-Thalassemia Major by Narayana Goruntla, P. Stephen Azarya, Mahitha Chalagundla, Dasaratha Ramaiah Jinka, Pradeepkumar Bhupalam, Vishnuvandana Bandaru

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Varicella Zoster Virus (VZV) Origin-Dependent Plasmid Replication in the Presence of the Four Overlapping Cosmids Comprising the Complete Genome of VZV

“…It has been shown that each of the seven genes required for ori-dependent DNA synthesis of Herpes Simplex Virus type-I (HSV) has a homologue in the VZV genome. …”
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Exact Solutions of Heat and Mass Transfer with MHD Flow in a Porous Medium under Time Dependent Shear Stress and Temperature by Arshad Khan, Ilyas Khan, Farhad Ali, Asma Khalid, Sharidan Shafie

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NATURAL KILLER CELL EFFECTS UPON ANGIOGENESIS UNDER CONDITIONS OF CONTACT-DEPENDENT AND DISTANT CO-CULTURING WITH ENDOTHELIAL AND TROPHOBLAST CELLS by K. L. Markova, O. I. Stepanova, A. R. Sheveleva, N. A. Kostin, V. A. Mikhailova, S. A. Selkov, D. I. Sokolov

“…Natural killer (NK) cells, macrophages and trophoblast have the most significant effect on angiogenesis. To date, the functions of cells participating in placenta formation have been described in detail, both individually (in vitrо) and in tissues (in situ). …”
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Age-structured malaria model with temperature-dependent dynamics and optimal control analysis within a partial differential equation framework. by Lukas Degu Petros, Temesgen Erena Abdisa, Dinka Tilahun Etefa, Dawit Kechine Menbiko, Ademe Kebede Gizaw, Eba Alemayehu Simma, Delenasaw Yewhalaw, Chernet Tuge Deressa

“…We analyze the existence and stability of equilibria, determined by the basic reproduction number R0, and demonstrate global stability through Lyapunov functionals. Numerical simulations show the effects of temperature variations and optimal controls on transmission dynamics, providing actionable insights for malaria management. …”
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PM2.5 affected ciliary beat frequency of axonemes via the cyclic AMP-dependent protein kinase a pathway by Jinyan Pang, Jinyan Pang, Zhiqin Xiong, Zhiqin Xiong, Kexin Zhang, Kexin Zhang, Yang Li, Yang Li

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Time-Dependent Fuzzy Reliability Analysis of Concrete Slab during the Initial Water Storage Period of CFRD: A Case Study by Gang Sun, Kongzhong Hu, Lifang Liu, Junru Li

“…Based on the Drucker–Prager yield criterion and tensile strength criterion, the response surface method is utilized to construct the performance functions at different moments, and then the time-dependent reliability analysis considering the fuzzy failure criteria is implemented for the concrete slab. …”
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Dose-dependent osteoimmunomodulatory effects of amorphous calcium phosphate nanoparticles promote 3D-printed scaffold-mediated bone regeneration by Ming Yan, Baixue Xiao, Anthony Yosick, Bei Liu, Hani A. Awad

“…The tunable osteoimmunomodulation by the NP underscores the translational potential of this technology to yield structurally sound and functionally robust bone regeneration outcomes.…”
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Temporal profiling of host transcriptome highlights time- and tissue-dependent Interferon pathway activation in NNV-infected European sea bass by Luca Peruzza, Giulia Dalla Rovere, Serena Ferraresso, Rafaella Franch, Daniela Bertotto, Francesco Pascoli, Gaia Bacchin, Anna Toffan, Luca Bargelloni

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