Leishmania regulates host YY1: Comparative proteomic analysis identifies infection modulated YY1 dependent proteins. by Harsimran Kaur Brar, Eleanor Chen, Fabian Chang, Shawna Angel Lu, Dilraj Kaur Longowal, Kyung-Mee Moon, Leonard J Foster, Neil Reiner, Devki Nandan

“…Interestingly, there are several cellular functions controlled by YY1 that could play a role in Leishmania pathogenesis. …”
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Time dependent performance analysis of a Smart Trash bin using state-based Markov model and Reliability approach by Pardeep Kumar, Amit Kumar

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SCFβ-TrCP targets Ajuba for degradation in a GSK3β-dependent manner in colorectal cancer by Liangshan Li, Feng Zhu, Yupei Liang, Yuanyuan Chen, Yongfu Pan, Lijun Jia, Shiwen Wang, Hu Zhao

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The TLR7/9 adaptors TASL and TASL2 mediate IRF5-dependent antiviral responses and autoimmunity in mouse by Ales Drobek, Léa Bernaleau, Maeva Delacrétaz, Sandra Calderon Copete, Claire Royer-Chardon, Mélissa Longepierre, Marta Monguió-Tortajada, Jakub Korzeniowski, Samuel Rotman, Julien Marquis, Manuele Rebsamen

“…The innate immune adaptor TASL mediates, via the interaction with SLC15A4, the activation of IRF5 downstream of human TLR7, TLR8 and TLR9, but the pathophysiological functions of this axis remain unexplored. Here we show that SLC15A4 deficiency results in a selective block of TLR7/9-induced IRF5 activation, while loss of TASL leads to a strong but incomplete impairment, which depends on the cell type and TLR engaged. …”
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RETRACTED ARTICLE: Sulforaphane induces S-phase arrest and apoptosis via p53-dependent manner in gastric cancer cells by Yuan Wang, Huazhang Wu, Nannan Dong, Xu Su, Mingxiu Duan, Yaqin Wei, Jun Wei, Gaofeng Liu, Qingjie Peng, Yunli Zhao

“…The Bax and cleaved-caspase-3 genes involved in apoptosis executive functions were significantly increased in a dose-dependent manner in BGC-823 and MGC-803 cells. …”
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Efficacy of Mentalization Based Group Therapy on Object Relations and Difficulties in Emotion Regulation: Outcome for Individuals with Dependent Personality Syndrome by Soheila Maleki, Lida Leilabadi, Shirin Kooshki

“…According to these findings, MBT-G is an effective intervention for improving psychological functioning in individuals with dependent personality syndrome, a condition that is classified under Cluster C personality disorders. …”
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Knockout of cyclin-dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice by Alexandra V Bruter, Ekaterina A Varlamova, Nina I Stavskaya, Zoia G Antysheva, Vasily N Manskikh, Anna V Tvorogova, Diana S Korshunova, Alvina I Khamidullina, Marina V Utkina, Viktor P Bogdanov, Iuliia P Baikova, Alyona I Nikiforova, Eugene A Albert, Denis O Maksimov, Jing Li, Mengqian Chen, Gary P Schools, Alexey V Feoktistov, Alexander A Shtil, Igor B Roninson, Vladislav A Mogila, Yulia Y Silaeva, Victor V Tatarskiy

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Evidence for a pro-proliferative feedback loop in prostate cancer: the role of Epac1 and COX-2-dependent pathways. by Uma Kant Misra, Salvatore Vincent Pizzo

“…Transfection of prostate cancer cells with Epac1 dsRNA, Raptor dsRNA, or Rictor dsRNA profoundly reduced Epac1-dependent increases in p-cPLA2 and COX-2.<h4>Conclusion</h4>We show that Epac1, a downstream effector of cAMP, functions as a pro-inflammatory modulator in prostate cancer cells and promotes cell proliferation and survival by upregulating Ras-MAPK, and PI 3-kinase-Akt-mTOR signaling.…”
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HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model. by Keira Sztukowski, Kaila Nip, Paige N Ostwald, Matheus F Sathler, Julianna L Sun, Jiayi Shou, Emily T Jorgensen, Travis E Brown, John H Elder, Craig Miller, Franz Hofmann, Sue VandeWoude, Seonil Kim

“…Among HIV-induced neuron-damaging products, HIV envelope glycoprotein gp120 triggers elevation of intracellular Ca2+ activity in neurons, stimulating various pathways to damage synaptic functions. We quantify neuronal Ca2+ activity using intracellular Ca2+ imaging in cultured hippocampal neurons and confirm that FIV envelope glycoprotein gp95 also elevates neuronal Ca2+ activity. …”
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Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure. by Tommi A White, Alberto Bartesaghi, Mario J Borgnia, Joel R Meyerson, M Jason V de la Cruz, Julian W Bess, Rachna Nandwani, James A Hoxie, Jeffrey D Lifson, Jacqueline L S Milne, Sriram Subramaniam

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CzcR-dependent reduction of catalase gene expression and induction of catalase activity in Pseudomonas aeruginosa during zinc excess by Ting Li, Zhifeng Mo, Yuying Zhao, Huiluo Cao, Shuo Sheng, Zeling Xu

“…Conclusion This study reported the opposite functions of CzcR in negatively regulating the expression of catalase genes katA and katB but in positively regulating the activity of catalase and H2O2 tolerance during Zn excess in P. aeruginosa.…”
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Temperature Dependent Spin Dynamics in La0.67Sr0.33MnO3/Pt Bilayers by Biswajit Sahoo, Akilan K, Katherine Matthews, Alexandre Pofelski, Alex Frañó, Eric E Fullerton, Sebastien Petit‐Watelot, Juan‐Carlos Rojas Sanchez, Sarmistha Das

“…Abstract Complex ferromagnetic oxides such as La0.67Sr0.33MnO3 (LSMO) offer pathways for creating energy‐efficient spintronic devices with new functionalities. LSMO exhibits high‐temperature ferromagnetism, half metallicity, sharp resonance linewidth, low damping, and a large anisotropic magnetoresistance response. …”
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The role of root dynamics on the climate sensitivity of ecohydrological processes of over- and understory in a semi-arid groundwater-dependent ecosystem by Qiyue Liu, Ana P. Barros

“…Plant roots connect belowground moisture with aboveground vegetation functionalities, making root plasticity critical for drought resilience. …”
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Psychological traits associated with anabolic androgenic steroid use and dependence: an exploratory cross-sectional study among female athletes by Morgan Scarth, Ingrid Amalia Havnes, Marie Lindvik Jørstad, Astrid Bjørnebekk

“…Group comparisons were made using Welch’s t-tests between control and AAS groups, and AAS dependent and non-dependent groups. Exploratory correlation analyses were computed between symptoms of dependence and behavioral and psychiatric scales. …”
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An Empirical Framework Characterizing the Metallicity and Star-formation History Dependence of X-Ray Binary Population Formation and Emission in Galaxies by Bret D. Lehmer, Erik B. Monson, Rafael T. Eufrasio, Amirnezam Amiri, Keith Doore, Antara Basu-Zych, Kristen Garofali, Lidia Oskinova, Jeff J. Andrews, Vallia Antoniou, Robel Geda, Jenny E. Greene, Konstantinos Kovlakas, Margaret Lazzarini, Chris T. Richardson

“…We present a new empirical framework modeling the metallicity and star formation history (SFH) dependence of X-ray luminous ( L ≳ 10 ^36 erg s ^−1 ) point-source population X-ray luminosity functions (XLFs) in normal galaxies. …”
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Stat3 oxidation-dependent regulation of gene expression impacts on developmental processes and involves cooperation with Hif-1α. by Michela Grillo, Carolyn Palmer, Nadine Holmes, Fei Sang, Andrew C Larner, Rahul Bhosale, Peter E Shaw

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Transcription factor TCF3 promotes bladder cancer development via TMBIM6-Ca2+-dependent ferroptosis by Wei-Feng Yang, Wei-Ming Guo, Qing-Tian Luo, Jingfen Lu, Zhou-Ke Tan, Yuan-Chun Ye, Gang Fan

“…The bladder cells were overexpressed or silenced with TCF3/TMBIM6 with ferroptosis inducer (Erastin)/Ca2+ blocker (BAPTA-AM) to investigate the effects on Ca2+-dependent ferroptosis and other functions. Finally, tumorigenicity was validated in nude mice. …”
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Cartographic and analytical assessment of land price formation depending on the physical and geographical conditions of the territory under military aggression in Ukraine by Петро Трофименко, Анна Мінженер, Віталій Зацерковний, Ірина Стахів, Світлана Кобилянська

“…The lack of clear legal regulation and the high risk of property loss lead to land purchase and sale transactions being carried out with significant restrictions, which do not meet the criteria for the full functioning of a market mechanism. Methods. Used research methods: geospatial data analysis (kriging method), mathematical statistics, cartographic-analytical assessment. …”
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Toxoplasma calcium-dependent protein kinases 3 mediates M1 macrophage polarization by targeting host Arginase-1 by Ran An, Fang Liu, Niuniu Dai, Fangmin Li, Xingyun Liu, Haijian Cai, Lijian Chen, Jian Du

“…Results The interaction between TgCDPK3 and Arginase-1 is functionally correlated and leads to a reduction in Arginase-1 activity, ultimately, contributing to the M1-biased phenotype of the host macrophages, which is related to restraining the proliferation of parasites. …”
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Size-dependent aggregation of erythrocytes by low molecular weight hyaluronic acids of different sizes: bioactivity and quality control potential by Xinyue Ma, Xiao Wang, XiaoXiao Jia, Jessica H. Hui, Joshua H. Shofaro, Ran Tao, Mizhou Matthew Hui

“…IntroductionHyaluronic acid (HA) is a crucial biological molecule whose diverse functions are strongly influenced by its molecular weight. …”
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