Smad4 and TGFβ1 dependent gene expression signatures in conditional intestinal adenoma, organoids and colorectal cancer by Mirvat Surakhy, Julia Matheson, David J. Barnes, Emma J. Carter, Jennifer Hughes, Claudia Bühnemann, Sabina Sanegre, Hans Morreau, Paul Metz, Charlotte J. Imianowski, Andrew Bassim Hassan

“…Murine adenoma identified Smad4 dependent gene expression signatures that require further evaluation as functional biomarker classifiers of SMAD4 mutated cancer subtypes.…”
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Structure-dependent degradation of milk oligosaccharides by newly isolated intestinal commensal bacterial strains from suckling piglets and rabbits by Mathilde Rumeau, Sead Chadi, Frederic Pepke, Martin Beaumont, Cláudia M. Vicente, Agathe Juppeau, Céline Vandecasteele, Laurent Cauquil, Géraldine Pascal, Philippe Langella, Christelle Knudsen, Sylvie Combes, Rebeca Martín

“…This study aims to investigate in vitro the functional relationship between the structural variability of milk oligosaccharides and the metabolic capacities of newly intestinal commensal bacteria isolated from suckling rabbits and piglets. …”
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ApoE2 affects insulin signaling in the hippocampus and spatial cognition of aged mice in a sex-dependent manner by Yu Wang, Hanchen Liu, Yijuan Ye, Wenting Fang, Anlan Lin, Xiaoman Dai, Qinyong Ye, Xiaochun Chen, Jing Zhang

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CD98hc, a novel of galectin-8 receptor, binds to galectin-8 in an N-glycosylation-dependent manner by Si Yunlong, Zhu Jiahui, Sayed Hend, Mayo Kevin H., Zhou Yifa, Tai Guihua, Su Jiyong

“…In addition, Gal-8 and its individual CRDs can pull down glycosylated CD98hc-ED but not free CD98hc-ED in vitro, indicating that the binding of Gal-8 to glycosylated CD98hc-ED is N-glycosylation-dependent. Overall, our findings establish CD98hc as a novel binding partner for Gal-8 and provide insights for further exploration of the diverse biological functions of Gal-8.…”
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Berbamine suppresses intestinal SARS-CoV-2 infection via a BNIP3-dependent autophagy blockade by Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Jimena Pérez-Vargas, Connor A. H. Thompson, Siobhan Ennis, Masahiro Niikura, Manon E. Wildenberg, Vanesa Muncan, Renée R. C. E. Schreurs, François Jean, Carla M. S. Ribeiro

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On the Enhanced p‐Type Performance of Back‐Gated WS2 Devices by Carlos Marquez, Farzan Gity, Jose C. Galdon, Alberto Martinez, Norberto Salazar, Lida Ansari, Hazel Neill, Luca Donetti, Francisco Lorenzo, Manuel Caño‐Garcia, Ruben Ortega, Carlos Navarro, Carlos Sampedro, Paul K. Hurley, Francisco Gamiz

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Algorithm for Finding Feedback in a Problem with Constraints for One Class of Nonlinear Control Systems by Michail G. Dmitriev, Zainelkhriet N. Murzabekov, Gulbanu A. Mirzakhmedova

“…For this, the solution of an auxiliary optimal control problem with a quadratic functional is used by analogy with the SDRE approach.Since this approach is used in the literature to find suboptimal synthesis in optimal control problems with a quadratic functional with formally linear systems, where all coefficient matrices in differential equations and criteria can contain state variables, then on a finite time interval it becomes necessary to solve a complicated matrix differential Riccati equations, with state-dependent coefficient matrices. …”
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The m6A writer KIAA1429 regulates photoaging progression via MFAP4-dependent collagen synthesis by Yuanyuan Liu, Jian Li, Chenhui Wang, Jiangbo Li, Kai Luo, Kang Tao, Yuan Tian, Xiang Song, Zhifang Zhai, Yuandong Tao, Jia You, Lihua Wu, Wenqian Li, Yuanyuan Jiao, Rongya Yang, Mingwang Zhang

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Sustainable inventory models for a three-echelon food supply chain with growing items and price- and carbon emissions-dependent demand under different emissions regulations by Makoena Sebatjane, Leopoldo Eduardo Cárdenas-Barrón, Amir Hossein Nobil

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The Technology of Socio-Professional Students Training for International Cooperation by Y. V. Troynicova

“…The methodology bases compiles the person-oriented, culture-oriented, communicative-functional approaches, which result in working out the personalized, subjectively functional, culture-creative methods and forms of training in the context of foreign language vocational education. …”
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Design of C24 fullerene-based sensors for gamma-butyrolactone detection as advanced tools for biomedical and pharmaceutical applications by Bader Huwaimel, Saad Alqarni

“…This study presents a sensor for GBL detection based on fullerene C24 and its beryllium-, calcium-, and magnesium-doped derivatives. Using density functional theory (DFT) and time-dependent DFT (TD-DFT), we optimized the structures and analyzed their electronic, optical, and quantum properties. …”
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Intergovernmental relations system in the Ethiopian Federation: normative considerations by Nigussie Afesha

“…The dysfunction of IGR forums and their implementation of IGR law are associated with the lack of political commitment by the government to depart from the informal IGR that relied upon the ruling party line to manage government functions, including IGR.…”
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Low-dimensional Magnetism in Compounds with Different Dimensions of Magnetic Interaction by M. S. Baranava

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Interplay between the cyclophilin homology domain of RANBP2 and MX2 regulates HIV-1 capsid dependencies on nucleoporins by Haley Flick, Ananya Venbakkam, Parmit K. Singh, Bailey Layish, Szu-Wei Huang, Rajalingam Radhakrishnan, Mamuka Kvaratskhelia, Alan N. Engelman, Melissa Kane

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Model for assessing the effectiveness of information security systems by Evgenii S. Mityakov, Svetlana V. Artemova, Anatoly A. Bakaev, Alexander V. Dushkin, Zhanna G. Vegera

“…Examples are given of the model metrics' dependence on parameters such as incident frequency and downtime, allowing for an assessment of the proposed model's effectiveness. …”
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Transition From Scenario-Based to Outcome-Based Engineering in SE4AI by Niloofar Shadab, Alejandro Salado, Tyler Cody, Peter Beling

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Molecular Insights into the Interaction of Orexin 1 Receptor Antagonists: A Comprehensive Study Using Classical and Quantum Computational Methods by Caio Sena, Pedro Albuquerque, Jonas Oliveira, Davi Vieira

“…In this study, we investigate the molecular interactions of three OXR1 antagonists—daridorexant, lemborexant, and suvorexant—using an integrated computational approach combining molecular dynamics (MD) simulations, density functional theory (DFT) calculations, and the molecular fractionation with conjugate caps (MFCC) methodology. …”
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Semiconductor‐to‐metal transition in platinum dichalcogenides induced by niobium dichalcogenides by Lei Zhang, Xin Zhou, Tong Yang, Yuan Chen, Fangjie Wang, Haoge Cheng, Dechun Zhou, Goki Eda, Zheng Liu, Andrew T. S. Wee

“…Density functional theory (DFT) calculations suggest that the metallization of PtSe2 on NbX2 and PtTe2 on NbTe2 results from interfacial orbital hybridization, while for PtTe2 on NbSe2, it is due to the strong p‐doping effect caused by interfacial charge transfer. …”
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Interactions of Nedaplatin with Nucleobases and Purine Alkaloids: Their Role in Cancer Therapy by Kamil Szupryczyński, Beata Szefler

“…Furthermore, this affinity was dependent on the computational method used and on the hydrolyzed form of Nedaplatin. …”
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Effects of Combined Vibration Ergometry and Botulinum Toxin on Gait Improvement in Asymmetric Lower Limb Spasticity: A Pilot Study by Harald Hefter, Dietmar Rosenthal, Sara Samadzadeh

“…<b>Objective:</b> Botulinum neurotoxin type A (BoNT/A) injections and the new vibration ergometry training (VET) are studied for their combined effect on improving functional mobility in patients with asymmetric lower limb spasticity. …”
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