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4321
Bacterial TonB-dependent transducers interact with the anti-σ factor in absence of the inducing signal protecting it from proteolysis.
Published 2024-12-01“…This regulation often entails a signal transfer pathway known as cell-surface signaling (CSS) that involves the TBDR itself that also functions as transducer (and is thus referred to as TBDT), a cytoplasmic membrane-bound anti-σ factor, and an extracytoplasmic function σ (σECF) factor. …”
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Effectiveness of neoton in patients with chronic heart failure depending on the left ventricular ejection fraction. Sub-analysis of the BYHEART study
Published 2022-12-01“…The results obtained demonstrate an increase in the quality of life and exercise tolerance, an improvement according to the CAS, a decrease in NT-proBNP levels, and an improvement in left ventricular systolic function in patients with both HFrEF and HFmrEF during the course of intravenous EPCr therapy.Conclusion. …”
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Staphylococcus aureus keratinocyte invasion is dependent upon multiple high-affinity fibronectin-binding repeats within FnBPA.
Published 2011-04-01“…Since both colonisation and skin infection are dependent upon the interaction of S. aureus with keratinocytes we hypothesised that this might select for FnBP function and thus composition of the FnBR region. …”
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4327
PI3K-dependent ERK is involved in GM-CSF-mediated activation of progenitor cells in a neovascularisation model
Published 2010-06-01“…Taken together, the results of the current study provide evidence that a PI3K-dependent ERK signalling pathway is, at least, partially responsible for the GM-CSF-mediated effects on EPC function.…”
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Genome of a stage-dependent cave-dwelling frog reveals the genetic mechanism of an extremely divergent biphasic life cycle
Published 2025-05-01“…Orho tadpoles exhibit suppressed visual function while retaining crystalline lens development. …”
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Resilient unit commitment against extreme cold events considering decision-dependent uncertainty-featured EV demand response
Published 2025-06-01“…To overcome the limitations of conventional modeling approaches for decision-independent uncertainty, an affine function-based tractable model reformulation is presented addressing decision-dependent uncertainty (DDU) in EV response. …”
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4332
Prediction of single nucleotide polymorphisms of RNA dependent RNA polymerase for the potato leafroll virus using computational and experimental approaches
Published 2025-08-01“…We utilized advanced online protein prediction tools to explore the impact of DNA mutations on protein function and structure. These tools enabled us to assess the potential level and location of disorder within proteins, providing crucial insights into their behavior. …”
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Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.
Published 2011-04-01“…We demonstrated that tyrosine 23 phosphorylation resulting in surface expression of ANXA2 is required for TGFβ-induced, Rho-mediated epithelial-mesenchymal transition (EMT), linking the cellular function of ANXA2 which was previously shown to be associated with small GTPase-regulated cytoskeletal rearrangements, to the EMT process in PDA. …”
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4334
A Sec-Dependent Effector from “<i>Candidatus</i> Phytoplasma ziziphi” Suppresses Plant Immunity and Contributes to Pathogenicity
Published 2025-05-01“…Emerging evidence highlights the critical role of phytoplasma-secreted effectors in pathogenesis, though few have been functionally characterized. Here, we identified a Sec-dependent effector, JWB790, from <i>Ca</i>. …”
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The Concentration-dependent Investigation of the Toxic Effects of the Anorectic Agent Sibutramine on the Electrical Activity of the Cardiomyocytes in Metabolic Syndrome Rat Heart
Published 2021-08-01“…In addition to the known mode of its action through brown adipose tissue thermogenesis, systemic actions reveal some side effects including alterations in cardiac function. Despite various clinical findings, the effect of SBT on cellular levels remains elusive. …”
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Bone Tissue Remodeling Features in Patients with Systemic Lupus Erythematosus Depending on the Degree of Bone Tissue Mineral Density Reduction
Published 2014-12-01“…In patients with SLE there are bone remodeling features depending on the degree of bone tissue mineral density reduction, namely, – in case of osteoporosis, diagnosed by the ultrasound densitometry, remodeling is caused by the significant disorders of osteoblasts and osteoclasts functions, in case of III degree osteopenia – of osteoblasts function.…”
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CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection
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4339
Perindopril and hydrochlorthiazide effects on endothelium-dependent vasodilatation and angiotensin-converting enzyme activity in patients with mild to moderate arterial hypertensio...
Published 2005-06-01“…During 12-week perindopril (PR) and hypothiazide (HT) therapy, to study its antihypertensive efficacy, as well as its influence on endothelial function (EF) and angiotensin-converting enzyme (ACE) serum activity, in patents with essential arterial hypertension (EAH). …”
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Non-Homogeneous Poisson Process Software Reliability Model and Multi-Criteria Decision for Operating Environment Uncertainty and Dependent Faults
Published 2025-05-01“…As software systems have diversified in functionality, their structure has become more complex, and the types of failures that can occur in software have also diversified, stimulating the development of diverse software reliability models. …”
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