Yoda1 Inhibits TGFβ-Induced Cardiac Fibroblast Activation via a BRD4-Dependent Pathway by Perwez Alam, Sara M. Stiens, Hunter J. Bowles, Hieu Bui, Douglas K. Bowles

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Striatal infusion of cholesterol promotes dose‐dependent behavioral benefits and exerts disease‐modifying effects in Huntington's disease mice by Giulia Birolini, Marta Valenza, Eleonora Di Paolo, Elena Vezzoli, Francesca Talpo, Claudia Maniezzi, Claudio Caccia, Valerio Leoni, Franco Taroni, Vittoria D Bocchi, Paola Conforti, Elisa Sogne, Lara Petricca, Cristina Cariulo, Margherita Verani, Andrea Caricasole, Andrea Falqui, Gerardo Biella, Elena Cattaneo

“…All tested doses prevented cognitive decline, while amelioration of disease‐related motor defects was dose‐dependent. In parallel, we found morphological and functional recovery of synaptic transmission involving both excitatory and inhibitory synapses of striatal medium spiny neurons. …”
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Features of ovarian steroidogenesis and endometrial hypertrophy during adjuvant therapy with tamoxifen in premenopausal patients with hormone-dependent breast cancer by A. Yu. Goryainova, A. I. Stukan, A. I. Trofimenko, A. A. Meshcheryakov

“…Group 1 included 42 patients without chemotherapy, group 2 included 41 patients with chemotherapy. Depending on the safety of the menstrual function, each group was divided into 2 subgroups. …”
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Time-of-day dependent promotion of keratinocyte differentiation by Cinnamomum cassia bark extract through the p38 MAPK Pathway. by Miji Yeom, Kyungeun Jeon, De-Hun Ryu, Deokhoon Park, Eunsun Jung

“…Chronic skin conditions such as atopic dermatitis stem from impairments in skin barrier function. Circadian rhythms affect skin blood flow and barrier characteristics, which are significant for understanding atopic dermatitis. …”
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Enhanced IgG1‐mediated antibody response towards thymus‐dependent immunization in CXCR1‐deficient mice by Jennifer Jaufmann, Melanie Carevic, Leyla Tümen, Derya Eliacik, Fee Schmitt, Dominik Hartl, Sandra Beer‐Hammer

“…Serum antibody levels overtime were analyzed according to their specificity by enzyme‐linked immunosorbent assay. B‐1 cell functionality was examined by IL‐5/IL‐5Rα‐dependent stimulation of peritoneal and splenic cells in vitro. …”
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Multiplicity dependence of hyperon and hypertriton production in Zr+Zr and Ru+Ru collisions at √sNN = 200 GeV by Li Dongsheng

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Pancreatic cancer cell-intrinsic transglutaminase-2 promotes T cell suppression through microtubule-dependent secretion of immunosuppressive cytokines by Anton Wellstein, Thomas Seufferlein, Alexander Kleger, Tim Eiseler, Anton Lahusen, Nora Minhöfer, Kim-André Lohse, Christine Blechner, Jessica Lindenmayer, Sabine Windhorst, Yuan-Na Lin

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The ubiquitin-conjugating enzyme, Ubc1, indirectly regulates SNF1 kinase activity via Forkhead-dependent transcription by Rubin Jiao, Liubov Lobanova, Amanda Waldner, Anthony Fu, Linda Xiao, Troy A. Harkness, Terra G. Arnason

“…The SNF1 kinase in Saccharomyces cerevisiae is an excellent model to study the regulation and function of the AMP-dependent protein kinase (AMPK) family of serine-threonine protein kinases. …”
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Suppression of Spry1 reduces HIF1α-dependent glycolysis and impairs angiogenesis in BRAF-mutant cutaneous melanoma by Barbara Montico, Giorgio Giurato, Roberto Guerrieri, Francesca Colizzi, Annamaria Salvati, Giovanni Nassa, Jessica Lamberti, Domenico Memoli, Patrizia Sabatelli, Marina Comelli, Arianna Bellazzo, Albina Fejza, Lucrezia Camicia, Lorena Baboci, Michele Dal Bo, Alessia Covre, Tuula A. Nyman, Alessandro Weisz, Agostino Steffan, Michele Maio, Luca Sigalotti, Maurizio Mongiat, Eva Andreuzzi, Elisabetta Fratta

“…Accordingly, Ingenuity Pathway Analysis identified “HIF1α Signaling” as the most significant molecular and cellular function affected by Spry1 silencing, whereas the glycolytic function was significantly impaired in Spry1 depleted BRAFV600-mutant CM cells. …”
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Targeting LINC02320 prevents colorectal cancer growth via GRB7-dependent inhibition of MAPK signaling pathway by Lingwei Zhang, Hong Chen, Yangmei Yang, Liangbo Zhao, Huimin Xie, Peixian Li, Xinrui Lv, Luyun He, Nian Liu, Benyu Liu

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Anti-PS IgG Immune Complexes Impair Macrophage Phagocytosis in SLE via LOX-Dependent Oxidative Stress by Guan H, Huang L, Liu Y, Zhu E, Chen L, Li W, Wu H, Zhang X, Qin R, Zheng J, Mo Y, Zhong M, Xu B, Dai X, Wei Q, Chen Y, Wang Q, Zheng Z, Ma K, Tang C

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Identification of Smad-dependent and -independent signaling with transforming growth factor-β type 1/2 receptor inhibition in palatogenesis by Yoshimi Suzuki, Akira Nakajima, Takayuki Kawato, Koichi Iwata, Mitsuru Motoyoshi, Charles F. Shuler

“…However, the balance between Smad-dependent/-independent signaling during palatal fusion with inhibited TβR1/2 functions is not fully understood. …”
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Nestin Regulates Autophagy‐Dependent Ferroptosis Mediated Skeletal Muscle Atrophy by Ubiquitinating MAP 1LC3B by Shunshun Han, Xiyu Zhao, Chunlin Yu, Can Cui, Yao Zhang, Qing Zhu, Mohan Qiu, Chaowu Yang, Huadong Yin

“…Phenotypic analyses included histopathology (HE staining), functional assessments (muscle strength, weight analysis, treadmill), and dystrophy evaluation (dystrophin staining). …”
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Improved Absolute Stability for a Class of Nonlinear Switched Delay Systems via Mode-Dependent Average Dwell Time by Juan Liu, Qingdao Huang

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Dependence of wear of friction pairs of the mechanism for loading solid household waste into a garbage truck on the characteristics of antifriction materials by O.V. Bereziuk, V.I. Savulyak, V.O. Kharzhevskyi, O.V. Serdiuk, V.Ye. Yavorskyi

“…The response surfaces of the objective function – wear of friction units of the garbage truck loading mechanism and their two-dimensional cross-sections in the planes of the influence parameters are shown, which allow to clearly illustrate the specified dependence of this objective function on individual influence parameters. …”
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mTOR inhibition triggers mitochondrial fragmentation in cardiomyocytes through proteosome-dependent prohibitin degradation and OPA-1 cleavage by Hugo E. Verdejo, Valentina Parra, Andrea del Campo, Cesar Vasquez-Trincado, Damian Gatica, Camila Lopez-Crisosto, Jovan Kuzmicic, Leslye Venegas-Zamora, Ursula Zuñiga-Cuevas, Mayarling F. Troncoso, Rodrigo Troncoso, Beverly A. Rothermel, Mario Chiong, E. Dale Abel, Sergio Lavandero

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Age-dependent changes in the expression and localization of LYZL4, LYZL6 and PCNA during testicular development in the Ashidan yak by Yongfu La, Zhongbang Li, Xiaoming Ma, Pengjia Bao, Min Chu, Xian Guo, Chunnian Liang, Ping Yan

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Effects of opium on hippocampal-dependent memory, antioxidant enzyme levels, oxidative stress markers, and histopathological changes of rat hippocampus by Ebrahim Abbasi, Fatemeh Mirzaei, Sodabeh Mashayekhi, Iraj Khodadadi, Alireza Komaki, Nafiseh Faraji, Seyed Alireza Vafaii

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PGC-1α-Dependent Mitochondrial Adaptation Is Necessary to Sustain IL-2-Induced Activities in Human NK Cells by Dante Miranda, Claudia Jara, Jorge Ibañez, Viviana Ahumada, Claudio Acuña-Castillo, Adrian Martin, Alexandra Córdova, Margarita Montoya

“…Human Natural Killer (NK) cells are a specialized heterogeneous subpopulation of lymphocytes involved in antitumor defense reactions. NK cell effector functions are critically dependent on cytokines and metabolic activity. …”
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Osteopontin regulates right ventricular failure through integrin ανβ3/PERK/CHOP-dependent inflammatory and apoptotic pathways by Xiaomei Yang, Xiaomei Yang, Xiaomei Yang, Xuyang Wang, Xuyang Wang, Kai Li, Qiming Deng, Yonghao Hou, Yonghao Hou, Yonghao Hou, Guangmin Xi, Kangping Lu, Kangping Lu, Zihua Liu, Yu Bai, Yu Bai, Yu Bai, Jianbo Wu, Jianbo Wu, Jianbo Wu, Jingui Yu, Peng Zhang

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