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3961
Integrating conspecifics negative density dependence, successional and evolutionary dynamics: Towards a theory of forest diversity
Published 2024-11-01“…Conspecific negative density dependence (CNDD) is also well-documented and reduces tree vital rates independently of succession strategies. …”
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3962
Examining Screen Time Features for Managing Problematic Smartphone Use and Dependence: An Extension of Technology Acceptance Model
Published 2025-01-01“…Problematic smartphone use and dependence (PSUD) causes significant concerns, often resulting from excessive and habitual smartphone usage beyond functional needs. …”
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3963
The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization.
Published 2024-12-01“…This suggests the pivotal role of PIP2 in the establishment of a functional nuclear architecture competent for gene expression.…”
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3964
Dose-dependent immunotoxic mechanisms of celastrol via modulation of the PI3K-Akt signaling pathway
Published 2025-05-01“…In contrast, low-dose celastrol suppressed PI3K-Akt signaling by downregulating mTOR, indicating dose-dependent modulation of immune function.ConclusionOur study demonstrates the dose-dependent immunotoxic effects of celastrol, which is toxic in high doses caused by activation of the PI3K-Akt signaling pathway, while low doses offer protection by blocking this signaling pathway. …”
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3965
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3966
Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance
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3967
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3968
Spin-dependent thermoelectric properties of a hybrid ferromagnetic metal/quantum dot/topological insulator junction
Published 2025-02-01“…We calculate the thermoelectric coefficients, including electrical conductance, Seebeck coefficient (thermopower), heat conductance, and the figure of merit, using the nonequilibrium Green’s function technique. The results are analyzed in terms of the emergence of new effects. …”
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3969
FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms
Published 2025-03-01“…Whereas FNDC5 overexpression in murine heart was cardioprotective, introduction of FNDC5-targeted shRNA into the myocardium was sufficient to trigger Bax up-regulation, ATR/Chk1 activation, oxidative stress, cardiac fibrosis, loss of ventricular function, and compromised animal survival. The detrimental impact of FNDC5 depletion on heart function could be mitigated via treatment with a Chk1 inhibitor identifying Chk1 hyperactivity as a causative factor in cardiac disease. …”
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3970
Molecular dynamics simulations reveal proton transfer pathways in cytochrome C-dependent nitric oxide reductase.
Published 2012-01-01“…That pathway is equivalent to the functional periplasmic cavity postulated in cbb(3) oxidase, which illustrates that the two enzymes share some elements of the proton transfer mechanisms and confirms a close evolutionary relation between NORs and C-type oxidases. …”
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3971
Numerical Determination of a Time-Dependent Boundary Condition for a Pseudoparabolic Equation from Integral Observation
Published 2024-12-01“…We develop a computational approach for recovering the solution and unknown boundary function. The results from numerical experiments are presented and discussed.…”
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3972
Classification of cerebral palsy: association between gender, age, motor type, topography and Gross Motor Function Classificação da paralisia cerebral: associação entre gênero, ida...
Published 2009-12-01“…Most hemiplegics children were rated in motor level I, children with diplegia were rated in motor level III, and quadriplegic children were rated in motor level V. Functional classification is necessary to understand the differences in cerebral palsy and to have the best therapeutic planning since it is a complex disease which depends on several factors.…”
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3974
Cost-based optimal distributed generation planning with considering voltage depended loads and power factor of DG
Published 2024-02-01“…In addition to evaluating the impact of parameters such as variation of energy price and load on objective function, effect of these parameters on location and size of DG is considered. …”
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3976
PD-1-dependent therapeutic effect of Trichinella spiralis cystatin on myocardial infarction in a mice model
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3977
High resolution profiling of cell cycle-dependent protein and phosphorylation abundance changes in non-transformed cells
Published 2025-03-01“…Integrated with complementary resources, our data link cycle-dependent abundance dynamics to functional changes and are accessible through the Cell Cycle database (CCdb), an interactive web-based resource for the cell cycle community.…”
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Spin dependent thermoelectric transport in a multiterminal quantum dot hybrid including a superconductor and ferromagnets
Published 2025-04-01“…Using the non-equilibrium Green’s function technique within the Hubbard-I approximation, local and non-local thermoelectric coefficients, along with their spin counterparts, such as electrical and thermal conductance, and the Seebeck coefficient are calculated up to linear order with respect to generalized forces. …”
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3980
The bile acid-sensitive ion channel is gated by Ca2+-dependent conformational changes in the transmembrane domain
Published 2025-07-01“…These results reveal the molecular principles governing gating of BASIC and its regulation by Ca2+ ions, demonstrating that Ca2+ ions modulate BASIC function via changes in protein conformation rather than solely from a pore-block, as proposed for other members of this superfamily.…”
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