Executive dysfunction in affective disorders: differences in bipolar affective disorder and depressive episode by S. A. Galkin, S. N. Vasilieva, G. G. Simutkin, S. A. Ivanova

“…To identify the differences in executive function (inhibitory control, working memory, cognitive flexibility) between patients with bipolar affective disorder and depressive episode.Materials and methods. …”
Get full text

SURVIVAL FUNCTIONS IN 40-59 YEAR OLD MALE COHORTS ACCORDING TO THE PRESENCE OF ARTERIAL HYPERTENSION AND/OR MYOCARDIAL INFARCTION AND VARIOUS HIGH DENSITY LIPOPROTEIDES CONCENTRATI... by V. V. Belov, A. A. Menshchikov

“…The influence of baseline CL HDL concentrations on the 30-years survival functions among men not related to CVD. The influence of CL HDL on 30-year survival rate depends on CVD status and the disease periods.…”
Get full text

Interaction of the TNFR-receptor associated factor TRAF1 with I-kappa B kinase-2 and TRAF2 indicates a regulatory function for NF-kappa B signaling. by Kalsoom Sughra, Andreas Birbach, Rainer de Martin, Johannes A Schmid

“…Co-expression of fluorescently tagged TRAF1 and TRAF2 at different ratios implied that TRAF1 can affect clustering and presumably the activating function of TRAF2 in a dose dependent manner.<h4>Conclusions/significance</h4>The observation that TRAF1 can either activate or inhibit the NF-kappa B pathway and the fact that it influences the oligomerization of TRAF2 indicates that relative levels of IKK2, TRAF1 and TRAF2 may be important for regulation of NF-kappa B activity. …”
Get full text

Interplay of fatty acids, insulin and exercise in vascular health by Kara C. Anderson, Jia Liu, Zhenqi Liu

“…Importantly, these effects are both functionally and structurally dependent, with saturated fatty acids as the primary culprits, while polyunsaturated fatty acids may support insulin sensitivity and endothelial function. …”
Get full text

Green synthesis of self-oriented flower-like Ag@Ag2O nanostructures functionalized with L-Tryptophan for colorimetric simultaneous determination of ultra-trace level of thiamin and... by Maryam Abbasi Tarighat, Zahra Khosravani, Gholamreza Abdi

“…Abstract The study focuses on the green synthesis of Ag@Ag2O nanostructures using Padina algae extract and functionalizing them with L-tryptophan to enhance their properties as a colorimetric sensor for simultaneous detection of ultra-trace levels of thiamin and riboflavin. …”
Get full text

Dynamic hand and finger load distribution patterns in the first year following surgically treated distal radius fracture by Johannes Karnatz, Christoph Harms, Dagmar-Christiane Fischer, Thomas Mittlmeier

“…The changes in grip pattern showed significant correlations with grip strength and partly with range of motion of finger and wrist as well as the QuickDASH score. Conclusions The dependence between changes in load distribution and different hand function parameters implies the particular additional value and validity of this helpful technique for individual assessment and rehabilitation of hand function. …”
Get full text

Measurement of flow-mediated dilatation using a pulse oximeter probe (Comparison with RH-PAT) by Satoshi SHIMAWAKI, Miyu TAKITA, Yuri KIMURA

“…Flow-dependent dilatation test using Endo-PAT is conventionally used to evaluate vascular endothelial function; however, this method is costly. …”
Get full text

Modeling severe uncontrolled asthma: Transitioning away from health states by Tereza Lanitis, Asif H. Khan, Irina Proskorovsky, Ivan Houisse, Andreas Kuznik, Siddhesh Kamat, Conrado Franco-Villalobos, Florence Joulain

“…The timing of these events is dependent on profile characteristics including lung function, asthma control, exacerbation history, and other baseline characteristics or contextual factors. …”
Get full text

A blockade of leukotriene-mediated Alox5 function provides a new strategy for the treatment of <i>JAK2</i>V617F-induced polycythemia vera by Yi Shan, Ngoc DeSouza, Noah Littman, Qiang Qiu, Kathy Nguyen, Yehua Yu, Golam Mohi, Shaoguang Li

“…However, the molecular mechanism underlying the function of Alox5 in PV remains elusive. It is well established that leukotrienes are important downstream molecules synthesized through the Alox5 pathway in leukocytes and play a key role in mediating Alox5 functions in human asthma. …”
Get full text

Comparative results of subjective assessment by professional athletes of the functional state of the knee joint after anterior cruciate ligament repair with semitendinosus and grac... by M. N. Velichko, A. U. Terskov, A. M. Belyakova, E. O. Hrabrova, A. V. Bodrov, A. V. Shturmin, A. S. Umnikov, A. A. Shurygina

“…Aim: to evaluate the subjective functional state of the knee joint in professional athletes after arthroscopic reconstruction of the anterior cruciate ligament depending on the type of the autograft.Materials and methods: the study included 37 professional athletes, divided into 2 groups. …”
Get full text

Predicting of Long-term Maintenance of Sinus Rhythm after Cardioversion in Patients with Nonvalvular Persistent Atrial Fibrillation by Zharinov O., Levchuk N., Ikorkin M., Sychov O.

“…General clinical investigation, ECG, transthoracic and transesophageal echocardiography for detailed evaluation of structure and function of atria and ventricles were performed in all patients. …”
Get full text

Surgical treatment of hand vascular anomalies: A case report by Kozarski Jefta, Pavlović Dragomir, Šijan Goran, Cvetanović Srđan, Stanković Goran

“…Their presence in the metacarpal region can cause different functional disorders. The extent of such disorders directly depends on the localization and size of vascular anomalies, duration and the nature of the anomaly growth as well as on eventual secondary complications such as ulceration or bleeding. …”
Get full text

ENERGY STATES OF PARTICLES IN A QUANTUM SIZED STRUCTURE WITH A COMPLEX SHAPED BAND DIAGRAM by Alexey Pashchenko, Oleksandr Gritsunov, Oksana Babichenko

“…In this case, the delocalization of the wave functions and the shift of the corresponding energy levels (the lowest energy levels in the structure under consideration) is expressed as strongly as in multilayer symmetric structures. …”
Get full text

Case Presentation: Functional Assessment of a CASR Variant Identified in a Patient with Hypercalcaemia Confirms Familial Hypocalciuric Hypercalcaemia in the Patient and a Sister Pr... by Bryan K. Ward, Kirsten A. Loffell, John P. Walsh, Warwick D. Howe, Suzanne J. Brown, Scott G. Wilson

“…However, novel CASR variants must undergo functional assessment before they can be definitively assigned a causative role in FHH. …”
Get full text

Cloning and Functional Analysis of Skin Host Defense Peptides from Yakushima Tago’s Brown Frog (<i>Rana tagoi yakushimensis</i>) and Development of Serum Endotoxin Detection System... by Taichi Aono, Saki Tamura, Yua Suzuki, Taichi Imanara, Ryosei Niwa, Yoshie Yamane, Tetsuya Kobayashi, Sakae Kikuyama, Itaru Hasunuma, Shawichi Iwamuro

“…This study aimed to identify HDPs with novel amino acid sequences from the skin of <i>Rana tagoi yakushimensis</i> and analyze their functions. <b>Methods:</b> cDNAs encoding HDP precursors were cloned and sequenced using RT-PCR and 3′-RACE. …”
Get full text

Does Lagenaria siceraria seed oil-enriched extender regulate sperm quality, oxidant/antioxidant markers, and sperm mitochondrial enzymes in chilled diluted rabbit semen? by Ramya Ahmad Sindi, Sameh A. Abdelnour, Ehab El-Haroun, Mohammed A. Alfattah, Yasser H. A. Saber, Asmaa M. Sheiha

Get full text

Rhizosphere microbiome metagenomics in PGPR-mediated alleviation of combined stress from polypropylene microplastics and Cd in hybrid Pennisetum by Si-Yu Zhao, Yue-Liang Meng, Zi-Han Yang, B. Larry Li, Yu-Ying Li, Hui Han, Ling Liu, Peng-Fei Duan, Zhao-Jin Chen

“…Moreover, metagenomic analysis was used to examine the effects of PGPR on the rhizospheric microbial community and function. The cocontamination of PP and Cd affected the growth of the hybrid Pennisetum differently depending on the size of the MPs particles, with the aboveground and underground lengths of the 6.5 μm PP + Cd experimental group being smaller than those of the 830 μm PP + Cd group. …”
Get full text

Evaluation of pharyngeal airway changes &amp; velopharyngeal function following Le-fort I osteotomy in cleft lip and palate patients- a systematic review &amp; meta analysis by Eldo Babu, Parvathy Ghosh, K. Sarika, Anju James, N.K. Sapna Varma, V.V. Ajith

“…Conclusion: Le-Fort I maxillary advancement increases pharyngeal airway volume; particularly in the nasopharyngeal and oropharyngeal regions; thereby improving breathing function, especially during sleep. However, the degree of airway expansion varies depending on the extent of surgery and preoperative airway conditions. …”
Get full text

Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparibResearch in context by Xiaonan Zhang, Natallia Rameika, Lei Zhong, Verónica Rendo, Margus Veanes, Snehangshu Kundu, Sandro Nuciforo, Jordan Dupuis, Muhammad Al Azhar, Ioanna Tsiara, Pauline Seeburger, Shahed Al Nassralla, Viktor Ljungström, Richard Svensson, Ivaylo Stoimenov, Per Artursson, Markus H. Heim, Daniel Globisch, Tobias Sjöblom

“…A tumour arising in an individual heterozygous for a functional and a loss-of-function (LoF) allele of a gene occasionally retain only the LoF allele. …”
Get full text

White matter hyperintensities and their impact in brain structure and function in alzheimer’s disease and behavioral variant frontotemporal dementia across Latin America and the Un... by Florencia Altschuler, Verónica Canziani, Matías Fraile-Vázquez, Raul Gonzalez-Gomez, Hernán Hernández, Sandra Baez, Joaquín Migeot, Sol Fittipaldi, Marcelo Adrian Maito, Agustina Legaz, Maria Eugenia Godoy, Sebastián Moguilner, Josephine Cruzat, Carlos Coronel-Oliveros, Enzo Tagliazucchi, Hernando Santamaria Garcia, Pablo Reyes, Diana L. Matallana, José Alberto Avila-Funes, Andrea Slachevsky, María I. Behrens, Nilton Custodio, Juan Felipe Cardona, Luis Ignacio Brusco, Martin A. Bruno, Ana L. Sosa Ortiz, Stefanie D. Pina-Escudero, Leonel T. Takada, Elisa de Paula Franca Resende, Katherine L. Possin, Maira Okada de Oliveira, Kun Hu, Brian Lawlor, Jennifer S. Yokoyama, Bruce Miller, Francisco Lopera, Adolfo Martin Garcia, Vicente Medel, Agustin Ibañez, Cecilia Gonzalez Campo

Get full text