Insight into the avidity–affinity relationship of the bivalent, pH-dependent interaction between IgG and FcRn by Johannes Reusch, Jan Terje Andersen, Ulrich Rant, Tilman Schlothauer

“…Monoclonal antibodies (mAbs) as therapeutics necessitate favorable pharmacokinetic properties, including extended serum half-life, achieved through pH-dependent binding to the neonatal Fc receptor (FcRn). …”
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Genetic risk-dependent brain markers of resilience to childhood Trauma by Han Lu, Edmund T. Rolls, Hanjia Liu, Dan J. Stein, Barbara J. Sahakian, Rebecca Elliott, Tianye Jia, Chao Xie, Shitong Xiang, Nan Wang, Tobias Banaschewski, Arun L. W. Bokde, Sylvane Desrivières, Herta Flor, Antoine Grigis, Hugh Garavan, Andreas Heinz, Rüdiger Brühl, Jean-Luc Martinot, Marie-Laure Paillère Martinot, Eric Artiges, Frauke Nees, Dimitri Papadopoulos Orfanos, Herve Lemaitre, Luise Poustka, Sarah Hohmann, Nathalie Holz, Juliane H. Fröhner, Michael N. Smolka, Nilakshi Vaidya, Henrik Walter, Robert Whelan, Gunter Schumann, Jianfeng Feng, Qiang Luo, IMAGEN Consortium

“…By analyzing brain responses to angry faces in a large-scale longitudinal adolescent cohort (IMAGEN), we identified two functional networks located in the orbitofrontal and occipital regions. …”
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Availability and functioning of neonatal care units and neonatal mortality across five regions in Tanzania: a baseline cross-sectional study in 127 CEmONC health facilities by Hege Ersdal, Nahya Salim, Siren Rettedal, Castory Munishi, Robert Moshiro, Felix Ambrose Bundala, Benjamin A Kamala, Godfrey Guga, Habib R Ismail, Paschal Francis Mdoe

“…Besides, 75% (30/40) of the functioning NCUs, had one to four beds only. Only 17% (22/127) of facilities had a neonatal admission register. …”
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Time dependency of thrombectomy for large artery atherosclerosis versus cardioembolic stroke subtypes: evidence from the ANGEL-ACT registry by Yue Yin, Hanlin Chen, Anxin Wang, Anxin Wang, Anxin Wang, Xiaoli Zhang, Xiaoli Zhang, Xiaoli Zhang, Miao Li, Ligang Song, Ligang Song, Ligang Song, Baixue Jia, Baixue Jia, Baixue Jia, Ning Ma, Ning Ma, Ning Ma, Dapeng Mo, Dapeng Mo, Dapeng Mo, Xuan Sun, Xuan Sun, Xuan Sun, Feng Gao, Feng Gao, Feng Gao, Yiming Deng, Yiming Deng, Yiming Deng, Zhongrong Miao, Zhongrong Miao, Zhongrong Miao

“…No significant difference was found in the 90-day clinical functional outcome between the LAA and CE patients when ORT was achieved within 240 min. …”
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Metabolic balance in colorectal cancer is maintained by optimal Wnt signaling levels by Katharina Imkeller, Giulia Ambrosi, Nancy Klemm, Ainara Claveras Cabezudo, Luisa Henkel, Wolfgang Huber, Michael Boutros

“…In this study, we integrate whole‐genome CRISPR/Cas9 screens with large‐scale multi‐omic data to delineate functional subtypes of cancer. We engineer APC loss‐of‐function mutations and thereby hyperactivate Wnt signaling in cells with low endogenous Wnt activity and find that the resulting engineered cells have an unfavorable metabolic equilibrium compared with cells which naturally acquired Wnt hyperactivation. …”
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Features of the Effect of Cataracts and Glaucoma on the Daily Activities of Patients with Sarcopenic Obesity by O. L. Fabrikantov, A. E. Kopylov, N. M. Agarkov

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ECONOMIC SECURITY OF THE REGION IN THE CONTEXT OF ITS POSITIONING by Д.O. Грицишен, В.О. Кучменко, Д.В. Заблодська

“…It has been proved that the effective functioning of the mechanism for ensuring the economic security of regions in the context of their positioning requires the effective functioning of all subjects synchronously, which made it possible to formulate a synergistic effect in a formalized form. …”
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THE ASYMMETRY OF INFORMATION ON FOOD MARKET AND CONSUMERS’ PREFERENCES – SOME ASPECTS by Renata Nestorowicz

“…The level of the asymmetry is differentiated depending on a product category. The following paper focuses on bioactive/functional food. …”
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Gender differences in advanced activities of daily living: evidence from the longitudinal study of health and aging in Mexico 2012–2018 by Martha A. Sánchez-Rodríguez, Mariano Zacarías-Flores, Lesly Estefanía Castañeda-Sánchez, Víctor Manuel Mendoza-Núñez

“…BackgroundPerforming advanced activities of daily living (AADLs) is a component of healthy aging (HA) because it involves functional capacity. The ability to perform them can be hampered by several factors, which appear different for men and women.ObjectiveTo evaluate the performance data of AADLs in older Mexican adults from Mexican Health and Aging Study (MHAS) from 2012 to 2018 and to determine the risk factors for not performing AADLs.MethodsA secondary longitudinal analysis of the 2012 and 2018 waves of the MHAS was conducted. …”
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Le cycle de vie urbain et dynamiques de counter-urbanisation dans un contexte nord-africain : cas du Maroc by Maryam Mazouz, Mohammed Mastere, Sana Ajjoul, Bouchta El Fellah

“…The urban life cycle theory suggests that urbanization occurs in phases according to the demographic evolution of the center of the Functional Urban Area (FUR) or its periphery. This paper aims to enrich the literature on urban life cycle theory by applying it to the context of a North African agglomeration: The Functional Urban Region (FUR) of Rabat, Morocco using demographic data from the period 1912-2014 (from the advent of the protectorate to the year of the last population census) as well as data on the mobility of the active population. …”
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Dynamical analysis for a hepatitis B transmission model with immigration and infection age by Suxia Zhang, Hongbin Guo, Robert Smith?

“…Global stability of the unique endemic equilibrium is shown by a Lyapunov functional for a special case.…”
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From Teleology to Backward Causation: How Do They Contribute to Our Understanding of the Nature of Concepts? by Marcin Poręba

“…The paper analyses the traditional concept of teleology, as well as its modern descendant, the concept of function (as used in the context of so-called functional explanations), against the background of such notions as purposive action, concepts, causality, time, and space-time. …”
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Effects of globa l warming on insect natural enemies by BAI Yueliang, ZHOU Wenwu, ZHU Zengrong

“…As ectotherms, insects are completely dependent on environmental temperature to grow, develop, and regulate various physiological functions. …”
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Bergamot and Olive Extracts as Beer Ingredients: Impact on Cell Viability, Reactive Oxygen Species, and RNA Expression of Antioxidant Enzymes by Maria Laura Matrella, Bruna Amenta, Francesco Canino, Angela Maffia, Tiziana Cocco, Mariateresa Russo, Adele Muscolo

“…This study explores the incorporation of bergamot juice and olive extract as functional ingredients in craft beer and their effects on antioxidant activity and cellular oxidative stress. …”
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Quantitative Super‐Resolution Imaging of Molecular Tension by Seong Ho Kim, Adam B. Yasunaga, Hongyuan Zhang, Kevin D. Whitley, Isaac T. S. Li

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A blade-pitch controller for a large wind turbine generator in the presence of time-varying delay and polytopic uncertainty by Alireza Rokhsari, Roozbeh Abolpour

“…Then, a novel algorithm is proposed to design a proper controller for this system based on the Lyapunov-Krasovskii functional approach. The proposed controller simultaneously compensates for the effects of both delay parameters and uncertain parameters. …”
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RESISTANCE TO ACETYLSALICYLIC ACID AND PREVALENCE OF THROMBOSIS IN PATIENTS WITH STABLE ANGINA by N. F. Putchinyan, N. V. Furman, P. Ya. Dovgalevskyi

“…To estimate the prevalence of atherothrombotic complications depending on platelet sensitivity to acetylsalicylic acids (ASA) in patients with stable angina.Material and methods. 96 patients with stable angina of II-III functional classes received basic therapy included ASA (125 mg daily) to prevent atherothrombotic complications. …”
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A study on the interaction of N–acetylneyramic acid with monosaccharides adsorpbted on ultrafine silica surface by L. M. Ushakova, E. M. Demianenko, M. I. Terets, V. V. Lobanov, N. T. Kartel

“…There is a growing interest in studying the interaction of ultrafine silica (UFC) with saccharides, in particular glucose and fructose, as well as with N-acetylneuraminic acid (NANA) (which is а part of the body’s cell membrane), for further creation of nanocomposites with biomolecules to use in biological systems. Using the density functional theory method (DFT) within the polarization continuum model (PCM), the interaction peculiarities of monosaccharides with silica surface were examined and the influence of the NANA molecule on this process was determined. …”
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Valorization of Olive Oil and Wine Industry Byproducts: Challenges and Opportunities in Sustainable Food Applications by María Rodríguez-Pérez, Beatriz García-Béjar, Emma Burgos-Ramos, Paula Silva

“…These byproducts contain bioactive compounds, including polyphenols, such as hydroxytyrosol, resveratrol, and flavonoids, which possess antioxidant and anti-inflammatory properties, making them valuable for the development of functional foods and nutraceuticals. A combined waste valorization strategy can enhance bioactive compound recovery and align it with circular economic principles. …”
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Two-dimensional boron nitride allotrope Irida-B12N12 with 3-6-8 membered rings and wide-bandgap semiconducting properties by Marcelo L. Pereira, Djardiel da S. Gomes, Kleuton A. L. Lima, Georges D. A. Nze, Fábio L. L. Mendonça, Luiz A. Ribeiro

“…First-principles calculations based on density functional theory (DFT) formalism and ab initio molecular dynamics (AIMD) simulations were performed to investigate its structural, mechanical, electronic, and optical properties. …”
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