The Ion Formation and Quantitative Response of Isoprene, Monoterpenes and Terpenoids in Ion Mobility Spectrometry with Atmospheric-Pressure Chemical Ionization as a Function of Tem... by Thomas Mayer, Ralf Petrich, Helko Borsdorf

“…In this study, we investigated the ion formation processes and the quantitative response of isoprene, monoterpenes and monoterpenoids as a function of the temperature of the spectrometer using a tritium ionization source. …”
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The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress. by Raymond Buser, Vanessa Kellner, Andre Melnik, Caroline Wilson-Zbinden, René Schellhaas, Lisa Kastner, Wojciech Piwko, Martina Dees, Paola Picotti, Marija Maric, Karim Labib, Brian Luke, Matthias Peter

“…In contrast to rtt101Δ and mms22Δ cells, mrc1Δ rtt101Δ and mrc1Δ mms22Δ double mutants complete DNA replication upon replication stress by facilitating the repair/restart of stalled replication forks using a Rad52-dependent mechanism. Our results suggest that the Rtt101(Mms22) E3 ligase does not induce Mrc1 degradation, but specifically counteracts Mrc1's replicative function, possibly by modulating its interaction with the CMG (Cdc45-MCM-GINS) complex at stalled forks.…”
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Mapping mangrove multi-trait functional diversity from satellite observations across dense and fragmented stands using spectral-biophysical derivatives by Nguyen An Binh, Leon T. Hauser

“…This study presents the first attempt to map mangrove functional diversity (FD) using a multi-trait-based approach, incorporating key spectral vegetation indexes as well as optically derived functional traits: leaf chlorophyll content (LCC), leaf mass per area (LMA), and equivalent water thickness (EWT) retrieved from Sentinel-2. …”
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Stem cell-derived exosomes: a potential therapeutic strategy for enhancing tendon stem/progenitor cells function in tendon-bone healing by Junjie Tang, Peng Shen, Xinyuan Wu, Minhao Chen, Hua Xu

“…This review provides an overview of the mechanisms and functions of stem cell-derived exosomes in altering the properties of TSPCs and facilitating tendon-bone healing. …”
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Macrophagic Ym1 orchestrates γδT cell-derived IL-17 production and keratinocyte functionality to mediate psoriasis-like skin inflammation by Wentao Zhang, Fei Li, Yu Wang, Meiyang Fan, Yan Zhao, Yanglong Guan, Yan Zhou, Shemin Lu, Rikard Holmdahl, Liesu Meng, Wenhua Zhu

“…Collectively, we conclude that Ym1 regulates γδT cell-derived IL-17 production and keratinocyte functionality, and thereby contributes to skin inflammation in mice.…”
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EFFECT OF INFLIXIMAB ON DYNAMICS OF FUNCTIONAL CLASS AND RADIOLOGICAL SIGN OF BONE AND CARTILAGINOUS TISSUES ALTERATION OF JOINTS IN PATIENTS WITH DIFFERENT TYPES OF JUVENILE ARTHR... by E.I. Alexeeva, A.M. Alekseeva, S.I. Valieva, T.M. Bzarova, R.V. Denisova, G.V. Mikhaleva

“…Authors made a conclusion that treatment with infliximab prevents progressing of bone and cartilaginous destruction in all types of AJ, not depending on intensity of its clinical activity. This medication provides for full functional recovery of joints and elimination of features of disablement in patients with good clinical activity.Key words: children, juvenile arthritis, infliximab, treatment.…”
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Functional analysis of the interdependence between DNA uptake sequence and its cognate ComP receptor during natural transformation in Neisseria species. by Jamie-Lee Berry, Ana Cehovin, Melanie A McDowell, Susan M Lea, Vladimir Pelicic

“…Our recent finding that ComP is the long sought DUS receptor in Neisseria species paves the way for the functional analysis of the DUS-ComP interdependence which is reported here. …”
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Features of Formation and Functioning of the Spanish Colonial Administration in America During the 16^th and 17^th Centuries by A. V. Dementiev

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Short-Term High Fat Intake Does Not Significantly Alter Markers of Renal Function or Inflammation in Young Male Sprague-Dawley Rats by Catherine Crinigan, Matthew Calhoun, Karen L. Sweazea

“…Morphology was determined by measuring changes in renal mass and microstructure. Kidney function was measured by analyzing urinary protein, creatinine, and hydrogen peroxide (H2O2) concentrations, as well as plasma cystatin C concentrations. …”
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Different whole body HIIT protocols do not promote different muscle thickness and functional adaptations among healthy physically active subjects by Alexandre L. Evangelista, Júlio B. B. de Camargo, Roberta L. Rica, Luiz Carlos Carnevali Júnior, Gregg S. Mallett, Valentina Bullo, Marco Bergamin, Stefano Gobbo, Danilo S. Bocalini

“…Morphological (ultrasound-derived muscle thickness of the vastus lateralis [MTVL]) and general fitness (muscle endurance and maximal oxygen consumption) assessments were performed at pre- and post-intervention moments.ResultsBoth training protocols elicited significant improvements in all dependent variables (p < 0.05), with no significant between-group differences.ConclusionRegardless of the training configuration, both WB-HIIT programs serve as time-efficient strategies to induce changes in muscle thickness of the vastus lateralis and functional adaptations in healthy, physically active young individuals.…”
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g-NK cells from umbilical cord blood are phenotypically and functionally different than g-NK cells from peripheral blood by Fei Gao, Mauricio Campos Mora, Michael Constantinides, Loïs Coenon, Caroline Multrier, Loïc Vaillant, Tianxiang Zhang, Martin Villalba

“…However, the prevalence, phenotype, and function of g-NK cells in umbilical cord blood (UCB-g-NK) remain unclear. …”
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High-thermal free vibration analysis of functionally graded microplates using a new finite element formulation based on TSDT and MSCT by Huu Trong Dang, Nhan Thinh Hoang, Quoc Hoa Pham, Trung Thanh Tran, Huy Gia Luong

“…This research aims to develop an effective computational method for analyzing the free vibration of functionally graded (FG) microplates under high temperatures while resting on a Pasternak foundation (PF). …”
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New insights into radioresistance in breast cancer identify a dual function of miR‐122 as a tumor suppressor and oncomiR by Isidro X. Perez‐Añorve, Claudia H. Gonzalez‐De la Rosa, Ernesto Soto‐Reyes, Fredy O. Beltran‐Anaya, Oscar Del Moral‐Hernandez, Marisol Salgado‐Albarran, Oscar Angeles‐Zaragoza, Juan A. Gonzalez‐Barrios, Daniel A. Landero‐Huerta, Margarita Chavez‐Saldaña, Alejandro Garcia‐Carranca, Nicolas Villegas‐Sepulveda, Elena Arechaga‐Ocampo

“…Our data indicate that up‐regulation of miR‐122 promotes cell survival in acquired radioresistant breast cancer and also suggest that miR‐122 differentially controls the response to radiotherapy by a dual function as a tumor suppressor an and oncomiR dependent on cell phenotype.…”
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Close Functional Coupling Between Ca2+ Release-Activated Ca2+ Channels and Reactive Oxygen Species Production in Murine Macrophages by Sheng-Wei Jin, Li Zhang, Qin-Quan Lian, Shang-Long Yao, Ping Wu, Xiao-Yan Zhou, Wei Xiong, Du-Yun Ye

“…These findings indicate that the LPS-induced intracellular [Ca2+]i increase depends on the Ca2+ entry through CRAC channels, and close functional coupling between CRAC and ROS production in murine macrophages.…”
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Evaluation of the Effects of Monosodium Glutamate Overconsumption on the Functions of the Liver, Kidney, and Heart of Male Rats: The Involvement of Dyslipidemia, Oxidative Stress,... by Heba M. Abdou, Amel H. El-Gendy, Rania Gaber Aly, Mekky M. Abouzied, Heba M. Eltahir, Sultan S. Al thagfan, Saber M. Eweda

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Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2. by Briar Jochim, Irini Topalidou, Nicolas Lehrbach

“…Thus, the extent to which SKN-1A/Nrf1 and SKN-1C/Nrf2 functions are distinct or overlapping has been unclear. …”
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INVERSION OF THE CONCEPT ABOUT BIOLOGICAL ROLE OF RENIN → ANGIOTENSIN-II → ALDOSTERONE SYSTEM AND FUNCTION OF ARTERIAL BLOOD PRESSURE AS A METABOLISM REGULATOR by V. N. Titov

“…In addition to the major role in the realization of the biological function of locomotion, AP is a physical factor involved in compensation of impaired functions of homeostasis, trophology, endoecology and adaptation. …”
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Prediction of the time course of callus stiffness as a function of mechanical parameters in experimental rat fracture healing studies--a numerical study. by Tim Wehner, Malte Steiner, Anita Ignatius, Lutz Claes

“…Based on this corroborated model, a fit curve function was derived which predicts the increase of callus stiffness dependent on bodyweight, fixation stiffness, and fracture gap size. …”
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Evidence of a persistent altered neural state in people with fibromyalgia syndrome during functional MRI studies and its relationship with pain and anxiety. by Patrick W Stroman, Roland Staud, Caroline F Pukall

“…Altered neural signaling in fibromyalgia syndrome (FM) was investigated with functional magnetic resonance imaging (fMRI). We employed a novel fMRI network analysis method, Structural and Physiological Modeling (SAPM), which provides more detailed information than previous methods. …”
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Tim-3-expressing macrophages are functionally suppressed and expanded in oral squamous cell carcinoma due to virus-induced Gal-9 expression by Jianfeng Dong, Lijun Cheng, Minchao Zhao, Xiangfeng Pan, Zhiqiang Feng, Dawei Wang

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