Planet Mass Function around M Stars at 1–10 au: A Plethora of Sub-Earth Mass Objects by Yayaati Chachan, Eve J. Lee

“…Instrumental sensitivity to such planets is low, and the number of objects we will discover is strongly dependent on the underlying planet mass function. In this work, we provide a physically motivated planet mass function by combining the efficiency of planet formation by pebble accretion with the observed disk mass function. …”
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Rapid transient production in plants by replicating and non-replicating vectors yields high quality functional anti-HIV antibody. by Frank Sainsbury, Markus Sack, Johannes Stadlmann, Heribert Quendler, Rainer Fischer, George P Lomonossoff

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The Effect of Knee Deformity on Pain Intensity and Functional Fitness in Middle Age Male with Nonspecific Chronic Low Back Pain by Shahnaz Shahrjerdi, Masoud Golpayegani, Saeid Basatpour Avar

“…The purpose of this study is to investigate the effects of the knee abnormalities on pain intensity and functional fitness in middle aged men with the chronic nonspecific low back pain. …”
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Association between ambient temperature and cognitive function in a community-dwelling elderly population: a repeated measurement study by Yann-Yuh Jou, Yuan-Ting C Lo, Wei-Peng Su, Shu-Hsuan Mei, Han-Bin Huang

“…Objectives Evidence on the associations between short-term and long-term air temperature exposure and cognitive function in older adults, particularly those in Asia, is limited. …”
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Effects of oral lycopene supplementation on vascular function in patients with cardiovascular disease and healthy volunteers: a randomised controlled trial. by Parag R Gajendragadkar, Annette Hubsch, Kaisa M Mäki-Petäjä, Martin Serg, Ian B Wilkinson, Joseph Cheriyan

“…Post-therapy EDV responses for lycopene-treated CVD patients were similar to HVs at baseline (2% lower, 95% CI: -30% to +30%, P = 0.85), also suggesting lycopene improved endothelial function.<h4>Conclusions</h4>Lycopene supplementation improves endothelial function in CVD patients on optimal secondary prevention, but not in HVs.…”
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Features the interaction of functional and metabolic remodeling of myocardium in comorbid course of ischemic heart disease and 2 type diabetes mellitus by Sergey A. Afanasiev, Dina S. Kondratieva, Margarita V. Egorova, Shamil D. Akhmedov, Olesya V. Budnikova, Sergey V. Popov

“…Aims: To study the features of functional remodeling of the heart muscle in coronary heart disease with and without type 2 diabetes mellitus (DM2) depend on the level of Ca2+-ATPase and the activity of enzymes involved in energy metabolism. …”
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THE EFFECT OF COMBINED ANTIHYPERTENSIVE THERAPY ON THE BASIC PARAMETERS OF THE LEFT VENTRICLE MYOCARDIUM STRUCTURE AND FUNCTION IN WOMEN WITH METABOLIC SYNDROME A... by V. V. Skibitskiy, A. V. Fendrikova, N. E. Pykhalova

“…To study the effect of combined antihypertensive therapy on the basic parameters of the left ventricle (LV) myocardium structure and function in women with arterial hypertension (HT), metabolic syndrome (MS) and hypothyroidism. …”
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Ribonuclease activity of Dis3 is required for mitotic progression and provides a possible link between heterochromatin and kinetochore function. by Hiroaki Murakami, Derek B Goto, Takashi Toda, Ee Sin Chen, Shiv I Grewal, Robert A Martienssen, Mitsuhiro Yanagida

“…<h4>Methodology/principal findings</h4>We show here that the progression of mitosis is arrested in dis3-54, and that segregation of the chromosomes is blocked by activation of the mitotic checkpoint control. This block is dependent on the Mad2 checkpoint protein. Double mutant and inhibitor analyses revealed that Dis3 is required for correct kinetochore formation and function, and that this activity is monitored by the Mad2 checkpoint. …”
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Cascading effects of malaria on hepatic function and gut microbiota: Investigating the prospective therapeutic utility of Phyllanthus amarus alkaloid extract by Innocent Onyesom, Chinwendu Obogheneophruhe Elu, Ugochukwu Uzuegbu, Cyril Chukwudi Dunkwu

“…Administration of P. amarus alkaloid extract in a dose-dependent manner effectively restored liver function markers, reduced Kupffer cell hyperplasia, normalized bile acid levels, and modulated gut microbiota composition, thereby mitigating both hepatic inflammation and apoptosis. …”
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High-Quality Assembly of the Apple Fungal Pathogen <i>Marssonina coronaria</i> Genome and Functional Analysis of Candidate Effectors by Huiting Guo, Yicong Fu, Lichi Zhong, Qiang Cheng

“…Two signal peptide-dependent cell death-inducing effectors were identified: McNLP1, containing an NPP1 domain, and McCEP3. …”
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Evaluation of the effect of locoregional treatment on metabolic liver function in hepatocellular carcinoma using 18F-FDGal PET/CT by Mona Kjærbøl Kristiansen, Kirstine Petrea Bak-Fredslund, Stine Kramer, Gerda Elisabeth Villadsen, Michael Sørensen

“…Abstract Background The effect of different locoregional treatments for hepatocellular carcinoma (HCC) on metabolic liver function is largely unknown. This information is crucial, particularly for patients with cirrhosis. …”
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Interrelationships between Skin Structure, Function, and Microbiome of Pregnant Females and Their Newborns: Study Protocol for a Prospective Cohort Study by Doris Wilborn, Jan Kottner, Kathrin Hillmann, Sa Xu, Frank Konietschke, Ulrike Blume-Peytavi

“…Pregnancy leads to several skin changes, but evidence about structural and functional skin changes is scarce. Findings on skin structure and function in children in their first year reveal rapid skin maturation, but evidence indicates that in particular, water holding and transport mechanisms are different from adults. …”
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Synbiotic-driven modulation of the gut microbiota and metabolic functions related to obesity: insights from a human gastrointestinal model by Kevin Mok, Putsawee Tomtong, Takuma Ogawa, Kenshiro Nagai, Pitchsupang Torrungruang, Suvimol Charoensiddhi, Jiro Nakayama, Bandhita Wanikorn, Sunee Nitisinprasert, Wanwipa Vongsangnak, Massalin Nakphaichit

“…Abstract Synbiotic interventions have gained increasing attention for modulating gut microbiota and metabolic functions in obesity-related disorders. This study evaluated the effects of Limosilactobacillus reuteri KUB-AC5 (10⁸ CFU) and Wolffia globosa powder (6 g/day) using an in vitro continuous human gastrointestinal model. …”
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Repetitive magnetic stimulation with iTBS600 induces persistent structural and functional plasticity in mouse organotypic slice cultures by Han Lu, Shreyash Garg, Maximilian Lenz, Andreas Vlachos

“…Background:: Repetitive transcranial magnetic stimulation (rTMS) is well known for its ability to induce synaptic plasticity, yet its impact on structural and functional remodeling within stimulated networks remains unclear. …”
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Tianqi pingchan granule promotes recovery of glymphatic system function in a rat model of l-DOPA-induced dyskinesia by Zhihua Liu, Shuyuan Yang, Lu Song, Yu Zhang, Ying Wan, Jing Gan, Na Wu, Zhenguo Liu

“…Three doses of TPG were administered once a day for 3 weeks to investigate the role of TPG in behavioural characteristics of LID rats. The glymphatic function was evaluated by utilizing intracisternal infusion of a fluorescenttracer. …”
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Functional and Therapeutic Roles of Plant-Derived Antioxidants in Type 2 Diabetes Mellitus: Mechanisms, Challenges, and Considerations for Special Populations by Vicente Javier Clemente-Suárez, Alexandra Martín-Rodríguez, Ana Isabel Beltrán-Velasco, Alejandro Rubio-Zarapuz, Ismael Martínez-Guardado, Roberto Valcárcel-Martín, José Francisco Tornero-Aguilera

“…Recent developments, such as nanoencapsulation, synergistic functional food formulations, and microbiome-targeted strategies, have shown promise in enhancing efficacy. …”
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Physical activity and functional preservation in older adults with hip osteoarthritis: A comparative analysis of age cohorts in the SHARE study. by Graziella Martins de Vasconcellos de Mello, Fernando Tadeu Trevisan Frajácomo, Ariele B Haagsma, Dyego L B Souza, Vanessa Barbosa de Oliveira, Márcia Olandoski, José Rocha Faria Neto, Javier Jerez-Roig, Cristina P Baena

“…<h4>Methods</h4>We analyzed data from Wave 5 of the Survey of Health, Aging, and Retirement in Europe (SHARE), constructing univariate and multivariable logistic regression models. Functional limitations served as dependent variables, with physical inactivity as the primary explanatory variable and number of chronic conditions, body mass index (BMI), gender, education, and depression as covariates.…”
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TRIMETAZIDINE INFLUENCE ON FILTRATION AND TUBULOINTERSTITIAL FUNCTION OF KIDNEYS IN ISCHEMIC HEART DISEASE PATIENTS WITH CHRONIC HEART FAILURE AND RENAL DYSFUNCTION by N. A. Koziolova, I. I. Kolegova, M. V. Surovtseva

“…Evaluation of trimetazidine influence on the parameters of filtration and tubulo-interstinal function of kidneys in angina patients of II-III functional class (FC) and stable chronic heart failure (CHF) of II-III FC with chronic kidney disease (CKD) stage 3.Material and methods. …”
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Efficacy of Centella asiatica on mitigating temporomandibular pain and improving functionality: a randomized, double blind, pilot clinical trial by Prangtip Potewiratnanond, Rudee Surarit, Mayuree H. Tantisira, Lakshman Samaranayake, Nattapon Rotpenpian, Aree Wanasuntronwong

“…Abstract Objective To determine the efficacy of Centella asiatica extract, ECa233, on alleviating pain symptoms and functional improvement of acute temporomandibular disorders (TMD). …”
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Association of plasma levels of Sestrin2 with adiposity and metabolic function indices in healthy and diabetic subjects from Qatar Biobank by Muhammad Ammar Zahid, Shahenda Salah Abdelsalam, Hicham Raïq, Hanan H. Abunada, Aijaz Parray, Abdelali Agouni

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