Electronic and optical properties of molybdenum disulfide (MoS2) mono layer using density functional theory (DFT) calculations by Zeleke Deressa Gerbi

“…This study employs first-principles calculations based on density functional theory and time-dependent density functional perturbation theory (TDDFPT) to investigate the material’s band structure, projected density of states (PDOS), absorption spectrum, dielectric function, and joint density of states (JDOS). …”
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Association between Anthropometry and Spirometry-based Lung Function Measures among Bengali Children and Adolescents of Asian Indian Origin by Milon Das, Rupak K. Ghosh, Arnab Ghosh

“…Obejective: To examine the association between body size using anthropometric measures and spirometry-based lung function in Asian Indian children aged 10–18 years. …”
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Biologically active peptides of meat and meat product proteins: a review. Part 2. Functionality of meat bioactive peptides by I. M. Chernukha, N. G. Mashentseva, D. A. Afanasev, N. L. Vostrikova

“…There is a growing commercial interest in peptides generated from meat proteins is in the context of health saving functional foods. The paper describes prospects, pros and cons of using bioactive peptides as functional food ingredients and biologically active food additives.…”
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Long-term persistence of functional thymic epithelial progenitor cells in vivo under conditions of low FOXN1 expression. by Xin Jin, Craig S Nowell, Svetlana Ulyanchenko, Frances H Stenhouse, C Clare Blackburn

“…Normal thymus function reflects interactions between developing T-cells and several thymic stroma cell types. …”
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Levodopa induces thyroid function regulation in a patient with thyroid hormone resistance and Parkinson’s disease: a case report by Gabriela Rozo-Paz, Clara Maria Ruiz-Forero, José David Suárez-Mera, Guillermo Monsalve Duarte, William Kattah Calderón

“…Patients may be asymptomatic, although clinical manifestations depend on the THR subtype. This entity commonly has abnormal thyroid function tests and can be confirmed by molecular analyses.Case presentationThe present study describes a 55 year-old female diagnosed with surgically resected papillary thyroid carcinoma. …”
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Multi-fidelity transfer learning for quantum chemical data using a robust density functional tight binding baseline by Mengnan Cui, Karsten Reuter, Johannes T Margraf

“…Consequently, the current scarcity of high-fidelity datasets (i.e. beyond semilocal density functional theory) represents a significant challenge for further improvement. …”
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Structural and functional deficits in a neuronal calcium sensor-1 mutant identified in a case of autistic spectrum disorder. by Mark T W Handley, Lu-Yun Lian, Lee P Haynes, Robert D Burgoyne

“…We have examined the effect of this mutation on the structure and function of NCS-1. From use of NMR spectroscopy, it appeared that the R102Q affected the structure of the protein particularly with an increase in the extent of conformational exchange in the C-terminus of the protein. …”
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Functional architecture of pancreatic islets identifies a population of first responder cells that drive the first-phase calcium response. by Vira Kravets, JaeAnn M Dwulet, Wolfgang E Schleicher, David J Hodson, Anna M Davis, Laura Pyle, Robert A Piscopio, Maura Sticco-Ivins, Richard K P Benninger

“…Insulin-secreting β-cells are functionally heterogeneous. Whether there exist cells driving the first-phase calcium response in individual islets, has not been examined. …”
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The Eps1p protein disulfide isomerase conserves classic thioredoxin superfamily amino acid motifs but not their functional geometries. by Shai Biran, Yair Gat, Deborah Fass

“…The Cys-X-X-Cys motif is at the solvent-exposed amino terminus of an α-helix, allowing the first cysteine to engage in nucleophilic attack on substrates, or substrates to attack the Cys-X-X-Cys disulfide, depending on whether the enzyme functions to reduce, isomerize, or oxidize its targets. …”
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EVALUATION OF SUBSOIL MASSIF STABILITY TAKING INTO ACCOUNT THE IRREGULARITY OF CONSTITUENT ROCKS ON THE BASIS OF A RANDOM SIZE AND FUNCTION MODEL by M. O. Allaev

“…The cost of activities and the likelihood of loss are functional stability factors. The arrived-at expression determines the optimal massif stability coefficient value, which will correspond with the minimum total cost of the exercise and with additional losses in the event of a landslide. …”
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Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility to NK Cell Killing but Reduce NK Cell Function. by Matthew Pace, James Williams, Ayako Kurioka, Andrew B Gerry, Bent Jakobsen, Paul Klenerman, Nneka Nwokolo, Julie Fox, Sarah Fidler, John Frater, CHERUB Investigators

“…However, HDACi may also inhibit CTL function, suggesting different immunotherapy approaches may need to be explored. …”
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Altered m6A RNA methylation profiles in depression implicate the dysregulation of discrete cellular functions in males and females by Haruka Mitsuhashi, Rixing Lin, Anjali Chawla, Naguib Mechawar, Corina Nagy, Gustavo Turecki

“…Using m6A sequencing, we identified a total of 30,279 high-confidence m6A peaks, exhibiting significant enrichment in genes related to neuronal and synaptic function. The m6A peaks between males and females with MDD that passed the significance threshold showed opposite m6A patterns, while the threshold-free m6A patterns were concordant. …”
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Ex vivo model of functioning human lymph node reveals role for innate lymphocytes and stroma in response to vaccine adjuvant by Joannah R. Fergusson, Jacqueline H.Y. Siu, Nitya Gupta, Edward Jenkins, Eloise Nee, Sören Reinke, Tamara Ströbel, Ananya Bhalla, Shyami M. Kandage, Thomas Courant, Sarah Hill, Moustafa Attar, Michael L. Dustin, Alex Gordon-Weeks, Mark Coles, Calliope A. Dendrou, Anita Milicic

“…We describe precision-cut human lymph node (LN) slices as a functioning, architecturally preserved, full-organ cross-sectional model system. …”
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Regulatory T Cell Function Is Not Affected by Antisense Peptide-Conjugated Phosphorodiamidate Morpholino Oligomer (PPMO)-Mediated TMPRSS2 Truncation by Sandra Gunne, Fiona K. Sailer, Lucas Keutmann, Marie Schwerdtner, Hong M. Moulton, Eva Böttcher-Friebertshäuser, Susanne Schiffmann

“…<b>Conclusions:</b> Treg function is not altered after TMPRSS2 truncation and therefore, no unwanted side effects in regard of Tregs are expected when using TMPRSS2-truncating PPMO as an anti-viral drug.…”
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Deciphering the multifaceted role of double-stranded RNA sensor protein kinase R: pathophysiological function beyond the antiviral response by Jiyoon Chung, Yerim Lee, Jimin Yoon, Yoosik Kim

“…By elucidating these diverse functions, we aim to highlight the perspectives in cellular dsRNA research and the therapeutic implications of targeting PKR, stimulating further research into this versatile and essential RNA-dependent kinase.…”
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Cross-sectional and longitudinal association between accelerometer-measured light-intensity physical activity and cognitive function in older adults by Jing-Han Jhan, Jiaren Chen, Ting-Fu Lai, Ting-Fu Lai, Jong-Hwan Park, Jong-Hwan Park, Jong-Hwan Park, Yung Liao, Yung Liao

“…Binary logistic regression analysis was used to examine the association between 3 h/day of LPA and cognitive functions. Baseline dependent variables were whether participants had overall cognitive impairment and whether scores of domain-specific MMSE were at the maximum level; in the follow-up analysis, the dependent variables were whether overall and domain-specific scores of MMSE maintained or increased (obtained by subtracting the baseline from the follow-up overall and individual domain MMSE scores).ResultsA total of 167 participants were included (52.10% female; 76.11 ± 6.47 years). …”
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PD-L2 of tumor-derived exosomes mediates the immune escape of cancer cells via the impaired T cell function by Tongfeng Liu, Shuwen Cheng, Bo Peng, Haojing Zang, Xiaofeng Zhu, Xuetong Wang, Xujie Zhao, Yinmin Gu, Yongbo Pan, Hongbo Hu, Shan Gao

“…Under immune competence condition, TDE-PD-L2 is hijacked by immune cells in a PD-1-dependent manner to systematically dampen function of T cells via the increased proportion of the regulatory T cells and the decreased proportion of cytotoxic CD8+ T cells in both tumor-infiltrating T cells and spleen. …”
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The role of TLR-4 gene in the functioning of the natural human immune system and the immunopathogenesis of chronic hepatitis C (literature review) by T.I. Koval, L.M. Syzova, N.O. Pryimenko, A.Н. Sydorenko, M.V. Kulіsh, V.I. Ilchenko, N.P. Lymarenko

“…The article analyzes and summarizes the data of professional scientific sources on the role of the TLR-4 gene in the functioning of the natural human immune system, as well as Asp299Gly polymorphism of this gene in the immunopathogenesis of CHC. …”
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Helix-bundle and C-terminal GPCR domains differentially influence GRK-specific functions and β-arrestin-mediated regulation by Edda S. F. Matthees, Raphael S. Haider, Laura Klement, Mona Reichel, Nina K. Blum, Verena Weitzel, Thimea Trüpschuch, Carla Ziegler, Julia Drube, Stefan Schulz, Carsten Hoffmann

“…While most G protein functions are well-established, the contributions of GRKs and arrestins remain incompletely understood. …”
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Experimental evaluation of differential voltage protection scheme based on a coherence function applied to AC machine stator windings by R. A. Mahmoud

“…The approach requires the acquisition of three-phase voltage measurements at the midpoints and complete terminals of the stator windings of the induction machine. The function of the numerical differential voltage relay can be performed using cross-coherence and auto-coherence coefficients quantified for the voltage measurements to determine and categorize the various faults. …”
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