Multi-omics dissection of CPNE1 reveals its prognostic value and immune-regulatory function in liver cancer by Liu Liu, He Hong, Weiwei Zhang, Xiang Li, Yuan Yao, Zhengjun Zhang, Guangyao Li

“…Using a series of bioinformatics analyses, including expression, correlation, and survival analyses, we predicted the upstream miRNAs and lncRNAs of CPNE1 and explored its regulatory network through the competitive endogenous RNA (ceRNA) mechanism. Subsequently, functional enrichment analysis was conducted to explore the related functions and signaling pathways of the target genes. …”
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FEATURES OF WRITTEN LANGUAGE COMMUNICATION BY MEANS OF THE UKRAINIAN LANGUAGE (on the example of official-business, epistolary and conversational-functional styles) by Catherine S. Bondarchuk, Olha A. Chumachenko

“…Over the centuries of its existence, the Ukrainian language has created various forms of language units that serve to adequately convey information, preserving the national traditions of Ukrainian culture. Each functional style of the Ukrainian language has specific language tools for covering events and concepts depending on the circumstances of communication, its purpose, taking into account the characteristics of communicators. …”
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Retinal Pigment Epithelial Cells Express a Functional Receptor for Glucagon-Like Peptide-1 (GLP-1) by Alessandra Puddu, Roberta Sanguineti, Fabrizio Montecucco, Giorgio L. Viviani

“…Since the retinal pigment epithelium (RPE), that forms the outer retinal barrier, has a key role in protecting from diabetic retinopathy (DR), we investigated the potential expression and function of GLP-1R in a RPE cell line. ARPE-19 cells were cultured in DMEM/F12 supplemented with 10% FBS. …”
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Soil function, properties and plant diversity–biomass patterns differ between grazed and non-grazed steppe ecosystems by Jia Mi, Jia Mi, Qianju Wang, Jun Ou, Jing Shi, Haiyan Pang, Ziheng Feng, Yongfei Bai, Yongfei Bai

“…Enclosure consistently enhanced AGB and plant height compared to grazing, while increasing the relative contribution of perennial grasses and forbs to productivity through functional group reorganization. However, biodiversity responses were site-specific, enclosure increased plant diversity at two sites but reduced it at another, revealing landscape-dependent results.DiscussionThe grazing reshaped ecosystem regulation through three key changes: (1) the relationship between soil nutrients and AGB was inverted, and demonstrated a negative correlation between diversity and AGB, (2) established the trade-off of the effects of BGB on AGB driven by soil properties (soil nutrients and pH), (3) microbial community restructuring from dual nutrient-pH regulation to pH-dominated control and (4) grazing strengthened plant biomass-diversity linkages, while enclosure prioritized soil nutrient-plant diversity correlations. …”
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Single-chain variable fragment affinity tuning can optimize anti-AML CAR-NK cell functionality by Marianna Zahurak, Ravi Varadhan, Ilias Christodoulou, Ruyan Rahnama, Jun Choe, Huilin Yang, Monika Kizerwetter, Christian Guaraca, Natalie Jordan Holl, Stamatia C Vorri, Megan Zinsky, Danielle G Jones, Nikol Garcia Espinoza, Yun-Huai Kuo, Jamie B. Spangler, Challice L. Bonifant

“…Affinity-based differences in functional activation and antitumor activity are dependent on time course and are scFv/epitope specific.…”
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Integrated bioinformatics and functional studies identify CDK9 as a potential prognostic biomarker and therapeutic target in AML by Zhibin Xie, Yang Xia, Zhongyu Li, Mengmeng Zhang, Yuanyuan Tan, Yuqing Han, Meng Wang, Pingping Zhang, Jiajia Li

“…This study investigated the potential role of cyclin-dependent kinase 9 (CDK9), a known regulator of gene expression, in AML pathogenesis and prognosis. …”
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Comprehensive physical rehabilitation of patients with heart failure: impact on clinical and functional status and analysis of problems related to the enrollment by Yu. L. Begrambekova, N. A. Karanadze, A. G. Plisyuk, Ya. A. Orlova

“…The groups did not differ significantly in other clinical, functional and laboratory parameters.Conclusion. Patients’ motivation to exercise was associated with younger age and better subjective health perception and did not depend on objective status. …”
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Reduced Glutathione Promoted Growth Performance by Improving the Jejunal Barrier, Antioxidant Function, and Altering Proteomics of Weaned Piglets by Zhimei Tian, Yiyan Cui, Miao Yu, Dun Deng, Zhenming Li, Xianyong Ma, Mingren Qu

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Natural ligand 3,3’-diindolylmethane functions as an AHR agonist to modulate angiogenesis and organ development in chicken embryos by Gee-yea Lim, Hao Chen, Woo-seon Song, Dong-hee Koh, Dong-ha Kim, Hisato Iwata, Eun-Young Kim

“…Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that is crucial for regulating various toxicological responses and physiological functions. …”
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Monitoring of the Effectiveness of Intensive Care and Rehabilitation by Evaluating the Functional Activity of the Autonomic Nervous System in Patients with Brain Damage by Yu. Yu. Kiryachkov, A. V. Grechko, D. L. Kolesov, A. A. Loginov, M. V. Petrova, M. Rubanes, I. V. Pryanikov

“…Purpose: evaluation of the clinical significance of parametric monitoring of the effectiveness of intensive care and rehabilitation based on the analysis of the functional state of the autonomous nervous system in patients with brain damage of different genesis.Materials and methods. …”
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Structural-geometric and functional indicators of the heart in patients with multiple myeloma after anti-tumor treatment and COVID-19 by B. B. Samura, M. O. Panasenko, T. O. Samura, I. V. Chorna

“…The aim of the study was to assess the predictive role of regional myocardial contractile function indicators in identifying the risk of cardiovascular events in patients with multiple myeloma. …”
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The Ecosystem Services Assessment of Wetlands based on the Classification of Hydrological-ecological Structures and Functions (Case study: Shadegan Wetland) by leila Rahimi, Bahram Malekmohammadi, Ahmad reza Yavari

“…The lotic part has a high potential for hydrological and biogeochemical functions such as water storage and detention, retention of sediments and particles, nutrient transformation, carbon sequestration, and all ecological functions. …”
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Minimizing Total Weighted Completion Time on Single Machine with Past-Sequence-Dependent Setup Times and Exponential Time-Dependent and Position-Dependent Learning Effects by Kaibiao Sun, Hongxing Li

“…By the exponential time-dependent learning effect, it means that the processing time of a job is defined by an exponent function of the total actual processing time of the already processed jobs. …”
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Prevalence of Functional Difficulty Among School-Aged Children and Effect on School Enrolment in Rural Southern India: A Cross-Sectional Analysis by Bobeena Rachel Chandy, Calum Davey, William E. Oswald, Saravanakumar Puthupalayam Kaliappan, Kumudha Aruldas, Lena Morgon Banks, Smitha Jasper, Guru Nagarajan, Sean Galagan, David S. Kennedy, Judd L. Walson, Beena Koshy, Sitara S. R. Ajjampur, Hannah Kuper

“…We show scale-dependent differences between age and socioeconomic groups in the effect of functional difficulty on enrolment. …”
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Comparison of Subjective and Objective Cognitive Function and Emotional State in Supratentorial Brain Tumors Before Surgery—Recognizing the Influence of Laterality by Lisa Schock, Karsten Wrede, Neriman Oezkan, Philipp Dammann, Marvin Darkwah Oppong, Oliver Gembruch, Ramazan Jabbarli, Ilonka Kreitschmann‐Andermahr, Sonja Siegel, Anna Lena Friedel, Adrian Engel, Hanah Hadice Karadachi, Lilith Philomena Laflör, Ulrich Sure, Yahya Ahmadipour

“…In right hemisphere tumor patients, there was no relation between subjective cognitive function and emotional state. Significant laterality differences for correlations of subjective and objective cognitive function were not found and were not significant within the two groups. …”
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Comprehensive genomic dependency landscape of a human colon cancer organoid by Sana Khalili, Atefeh Mohseninia, Changlong Liu, Carolyn E. Banister, Paige Heine, Minou Khazan, Sidney E. Morrison, Prashanth Gokare, Glenn S. Cowley, Barbara A. Weir, David Pocalyko, Kurtis E. Bachman, Phillip J. Buckhaults

“…Abstract Identifying genetic dependencies in human colon cancer could help identify effective treatment strategies. …”
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Selection of the Best Copula Function in Bivariate Analysis of Water Resources Components (Case study: Siminehrood River Basin, Iran) by Fahimeh Sharifan, Yousef Ramezani, Mahdi Amirabadizadeh, Carlo De Michele

“…Then, by examining the dependence structure and the structure of copulas and using NSE, RMSE and BIAS evaluation criteria, Clayton's copula function was selected for all three pair of parameters, which was used to create a joint probability distribution between the pair of parameters in the Siminehrood River Basin.…”
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Reducing the Parameter Dependency of Phase-Picking Neural Networks with Dice Loss by Yongsoo Park, Gregory C. Beroza

“…Here, we test the Dice loss, which is a preferred loss function for highly imbalanced image segmentation problems. …”
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Dependency of Catalytic Reactivity on the Characteristics of Expanded Graphites as Representatives of Carbonaceous Materials by Do Gun Kim, Seong Won Im, Kyung Hwan Ryu, Seoung Ho Jo, Min Gyeong Choe, Seok Oh Ko

“…Rather, the reactivity is governed by the characteristics, i.e., defects and functional groups of the graphitic structure. It is thought that this study provides valuable insights into the development of highly reactive CMs and the catalytic systems using them.…”
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Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes by Victoria L. Haley, David J. Barnes, Ionel Sandovici, Miguel Constancia, Christopher F. Graham, Francesco Pezzella, Claudia Bühnemann, Emma J. Carter, A. Bassim Hassan

“…Here, we tested whether loss of function of p53 leads to IGF2 ligand pathway dependency in vivo. …”
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