Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury by Almir Aljović, Anne Jacobi, Maite Marcantoni, Fritz Kagerer, Kristina Loy, Arek Kendirli, Jonas Bräutigam, Luca Fabbio, Valérie Van Steenbergen, Katarzyna Pleśniar, Martin Kerschensteiner, Florence M Bareyre

“…Abstract Functional recovery following incomplete spinal cord injury (SCI) depends on the rewiring of motor circuits during which supraspinal connections form new contacts onto spinal relay neurons. …”
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Environmental enrichment alleviates neuropathic pain-associated anxiety by enhancing the function of parvalbumin interneurons in the anterior cingulate cortex by Zhuo-Yu Ren, Bao-Yu Han, Li-Yuan Zhao, Xue-Jie Lou, Yuan-Xiang Tao, Guang-Fen Zhang, Jian-Jun Yang

“…In addition, EE reversed the SNI-induced reduction in the number of PV puncta around Ca²⁺/calmodulin-dependent protein kinase II-positive neurons. Furthermore, enhancing the function of PV interneurons could effectively improve the SNI-caused anxiety-like behaviors. …”
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Candida albicans aspartyl protease (Sap6) inhibits neutrophil function via a “Trojan horse” mechanism by Marcin Zawrotniak, Dorota Satala, Magdalena Juszczak, Grażyna Bras, Maria Rapala-Kozik

“…Our findings revealed Sap6’s unique ability to bind and internalize in neutrophils, significantly attenuating ROS production through proteolytic damage to NADPH oxidase, resulting in blocking the ROS-dependent NETosis pathway. This disruption in neutrophil functions by Sap6 suggested the presence of a ‘Trojan horse’ mechanism by C. albicans. …”
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Coiled-coil-domain-mediated TRIM E3 protein condensation modulates enzymatic activity and functional specificity by Qi Chen, Peiguo Yang

“…Summary: Tripartite motif (TRIM) proteins are E3 ligases with modular structures involved in diverse cellular functions. Whether biomolecular condensation broadly regulates TRIM proteins remains unclear. …”
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Celecoxib Enhances Oxidative Muscle Fibre Formation and Improves Muscle Functions Through Prokr1 Activation in Mice by Jeong Hwan Park, Jongsoo Mok, Seoah Park, Dooho Kim, Min‐Su Kang, Tae Sub Park, Joonghoon Park

“…Prokineticin receptor 1 (PROKR1) has emerged as a potential target to improve muscle function through increasing oxidative muscle fibres, but there are no clinically applicable synthetic PROKR1 agonists. …”
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Cycle inhibiting factors (CIFs) are a growing family of functional cyclomodulins present in invertebrate and mammal bacterial pathogens. by Grégory Jubelin, Carolina Varela Chavez, Frédéric Taieb, Mark J Banfield, Ascel Samba-Louaka, Rika Nobe, Jean-Philippe Nougayrède, Robert Zumbihl, Alain Givaudan, Jean-Michel Escoubas, Eric Oswald

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Global Stability with Lyapunov Function and Dynamics of SEIR-Modified Lassa Fever Model in Sight Power Law Kernel by Muhammad Farman, Cicik Alfiniyah, Muhammad Saqib

“…Using the Volterra-type Lyapunov function, we investigate the global stability of the suggested system with a fractional Caputo derivative. …”
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Effect of Individualized Head-Related Transfer Functions on Distance Perception in Virtual Reproduction for a Nearby Sound Source by Guangzheng YU, Liliang WANG

“…The head-related transfer function (HRTF) is dependent on the position of the sound source (both direction and distance) and is also affected by individual anatomical parameters. …”
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RETRACTED: IAV Antagonizes Host Innate Immunity by Weakening the LncRNA-LRIR2-Mediated Antiviral Functions by Na Chen, Baoge Zhang

“…In addition, the antiviral function of LRIR2 is mainly dependent on the stem-loop structures of 1–118 nt and 575–683 nt. …”
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Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in 3xTg Alzheimer’s model mice by Grace Cunliffe, Li Yang Tan, Sangyong Jung, Jonathan Turner, John Gigg

“…Alongside memory loss, these cognitive deficits are amongst the most frequently reported symptoms of Alzheimer’s disease (AD). Normal executive function depends on connectivity between the ventral hippocampus and medial prefrontal cortex (mPFC), yet abnormalities in this circuit and how such changes lead to cognitive dysfunction in AD have yet to be fully elucidated. …”
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The Impact of Radioiodine (131I) Therapy of Thyroid Disease on Salivary Glands Function and Inflammation: A Comprehensive Review by Pietro Bellini, Francesco Dondi, Carlo Cappelli, Elisa Gatta, Davide Lombardi, Claudio Casella, Riccardo Morandi, Gianluca Viganò, Luca Camoni, Michela Cossandi, Valentina Zilioli, Francesco Bertagna

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Thermodilution-Based Invasive Assessment of Absolute Coronary Blood Flow and Microvascular Resistance: Quantification of Microvascular (Dys)Function? by Daniëlle C. J. Keulards, Mohamed El Farissi, Pim. A. L Tonino, Koen Teeuwen, Pieter-Jan Vlaar, Eduard van Hagen, Inge. F. Wijnbergen, Annemiek de Vos, Guus R. G. Brueren, Marcel van’t Veer, Nico H. J. Pijls

“…Since these small vessels are not visible by the human eye, physiologic measurements should be used to characterize their function. The invasive methods presently used (coronary flow reserve (CFR) and index of microvascular resistance (IMR)) are operator-dependent and mandate the use of adenosine to induce hyperemia. …”
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Probabilistic Forecasting of Offshore Wind Power Based on Dual-stage Attentional LSTM and Joint Quantile Loss Function by Xiangjing SU, Haibo YU, Yang FU, Shuxin TIAN, Haiyu LI, Fuhai GENG

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ANTIPLATELET TREATMENT IN ST ELEVATION ACUTE CORONARY SYNDROME UNDER REAL CLINICAL CIRCUMSTANCES: THE DYNAMICS OF THROMBOCYTE FUNCTION by L. I. Malinova, N. V. Furman, P. V. Dolotovskaya, N. F. Puchinian, I. Yu. Radaeva

“…To evaluate the dynamics of thrombocyte functional activity (TFA) under antiplatelet treatment conditions which include the branded, and generic compounds as well, in ST elevation acute coronary syndrome patients (STEACS) in routine clinical practice.Material and methods. …”
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Functional Fruit Snacks Enriched with Natural Sources of Fructooligosaccharides: Composition, Bioactive Compounds, Biological Activity, and Consumer Acceptance by Paulina Nowicka, Michalina Marcińczak, Martyna Szydłowska, Aneta Wojdyło

“…The results indicate the potential of using FOS as a functional additive, but their effects on taste and texture require further optimization.…”
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An animal model with a cardiomyocyte-specific deletion of estrogen receptor alpha: functional, metabolic, and differential network analysis. by Sriram Devanathan, Timothy Whitehead, George G Schweitzer, Nicole Fettig, Attila Kovacs, Kenneth S Korach, Brian N Finck, Kooresh I Shoghi

“…In light of the wide systemic influence of ER signaling in regulating a host of biological functions in multiple tissues, it is difficult to infer the direct role of ER on the heart. …”
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Assessment of the level of security (safety of functioning) of automated systems based on their vulnerabilities, formalized using the theory of queuing systems by A. O. Efimov, E. A. Rogozin

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Evaluation of the character of structural and functional changes in cerebral vessels in patients with ischemic cerebrovascular diseases on the background of multifocal lesions. by O. A. Rosits'ka

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A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division. by Josh R Beck, Imilce A Rodriguez-Fernandez, Jessica Cruz de Leon, My-Hang Huynh, Vern B Carruthers, Naomi S Morrissette, Peter J Bradley

“…Targeting of all three ISPs is dependent upon N-terminal residues predicted for coordinated myristoylation and palmitoylation. …”
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Tazul Tajuddin’s Opera Serikandi Nusantara: The Diminution of Functional Tonality and Its Symbolic Role from an Esthesis Perspective by Mohd Adam Masumi, Tazul Izan Tajuddin

“…It conjures up a sense of departure from the conventions of functional tonality in which the musical ideas are organised through the contemporary musical language and imaginative use of instrumental timbre and extended techniques. …”
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