Predictive Value of Urinary KIM-1, TIMP-2 and sTREM-1 for Contrast-Induced Acute Kidney Injury in Elderly Patients After Percutaneous Coronary Intervention by Huang W, Wang R, Zhang P

“…At 24 h and 48 h postoperatively, eGFR in the CI-AKI group was lower versus the non-CI-AKI group; urinary KIM-1 and sTREM-1 in the CI-AKI group were higher in contrast to the non-CI-AKI group; TIMP-2 in the CI-AKI group was higher versus that in the non-CI-AKI group. ROC curve analysis showed that the areas under the curve (AUCs) for urine KIM-1, TIMP-2, and sTREM-1 in diagnosing CI-AKI at 6 hours postoperatively were 0.852 (95% CI: 0.768– 0.936), 0.810 (95% CI: 0.723– 0.898), and 0.874 (95% CI: 0.804– 0.943), and the cut-off values were 45.93 ng/L, 1.63 ng/mL, and 61.48 ng/L, respectively, with sensitivities of 66.70%, 58.30%, and 72.20%, and specificities of 95.00%, 93.00%, and 91.00%, respectively (all P < 0.05).Conclusion: Urinary KIM-1, TIMP-2 and sTREM-1 can respond to early changes in renal function after PCI and have good application value in the early diagnosis of CI-AKI.Keywords: percutaneous coronary intervention, kidney injury molecule-1, tissue inhibitor of metalloproteinases-2, soluble triggering receptor expressed on myeloid cells-1, contrast-induced acute kidney injury…”
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SYSTEMIC LUPUS ERYTHEMATOSUS AND INFECTIVE ENDOCARDITIS: CLINICAL AND DIAGNOSTIC PARALLELS AND IMAGINARY MIMICRY by S. P. Filonenko, A. A. Nikulina, E. A. Smirnova, E. V. Korotchenko

“…These data, combined with the history of the disease (fever for several months) confirmed diagnosis of infective endocarditis, despite the absence of vegetations on heart valves. …”
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New tectonic discrimination diagrams for basic and ultrabasic volcanic rocks through log-transformed ratios of high field strength elements and implications for petrogenetic proces... by Surendra P. Verma, Salil Agrawal

“… The statistically correct handling of compositional data requires log-ratio transformation whereas the multivariate technique of linear discriminant analysis (LDA) assumes a normal distribution of the transformed variables. …”
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Reference charts for the fetal cavum septi pellucidi’s width, length and length-to-width ratio: protocol for a prospective monocentric cross-sectional study in Italy (the ‘REC-FAST... by Patrizia Vergani, Sara Ornaghi, Anna Locatelli, Elena Spada, Roberta Rovelli, Maria Verderio, Paola Camponovo, Laura Lanteri, Elettra Salmoiraghi, Sabrina Cozzolino

“…Where possible, outliers will be corrected by comparing with the original values (computation errors); otherwise, such data will be excluded. The fetal charts will be traced using the Cole and Green-Lambda, Median, and Sigmamethod (CG-LMS); in addition, the use of alternative modelling approaches, such as parametric models derived from the Extended Mechanistic Growth Function method, will be explored.Ethics and dissemination Ethical approval for this study was obtained by the Lombardy Ethics Committee n.3 (15 December 2023) prior to the commencement of the research. …”
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Dietary inflammatory index and mortality in middle-aged and elderly patients with metabolic syndrome by Xiangmei Li, Lei Liu, Xing Li, Long Yang, Li Men

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Prescribing with precision: fluids, food and furosemide by Rand Al-Assadi, Huda Mahmoud, Rebecca Jackson, Holly Trippe

“…Methods: This retrospective study examined electronic and paper records of individuals over 65 years admitted to medical wards. Data collected included patient demographics, weight documentation, rationale for NBM status or maintenance fluids, prescribed fluid volumes and types, electrolyte abnormalities and corrections, and renal function (including community and/or hospital-acquired acute kidney injury). …”
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Research on knowledge, attitude and practice (KAP) regarding dengue infection: a community-based study in rural Cox's Bazar by Saima Bibi

“…Problem: DI poses a serious threat to public health, especially in tropical and subtropical areas where the dengue virus vector, the Aedes aegypti mosquito, is abundant.1,2 Bangladesh experienced its major dengue outbreak in 2019, with 100,000 cases and 120 deaths, followed by the second-largest outbreak in 2022, with 60,078 cases and 266 deaths.3,4 Assessment of problem and analysis of its causes: Bangladesh is severely affected by DI, largely due to factors including tropical climate, a dense population, unplanned urbanisation, inadequate vector control and low-literacy rates.5,6DI can cause mild fever to severe conditions, such as haemorrhagic fever, dengue shock syndrome, respiratory symptoms, gastrointestinal disturbance, low platelet count and deranged liver function tests. …”
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Wastewater metagenomics in Africa: Opportunities and challenges. by Stephen Kanyerezi, Fatma Zahra Guerfali, Abbas Abel Anzaku, Oluwasegun Adesina Babaleye, Tracey Calvert-Joshua, Julien Alban Nguinkal, Oluwaseun Paul Amoo, Chiraz Atri, Waqasuddin Khan, Iqra Saleh, M Imran Nisar, Arthur Shem Kasambula, Koketso Morapedi, Gerald Mboowa

“…The advent of metagenomics has dramatically expanded our understanding of microbial communities, particularly through the study of wastewater, which serves as a rich source of microbial data. In Africa, wastewater metagenomics presents unparalleled opportunities for public health monitoring, antimicrobial resistance (AMR) tracking, and the discovery of new microbial species and functions. …”
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Kharon Is Crucial for <i>Trypanosoma cruzi</i> Morphology but Does Not Impair In Vitro Infection by Jose Luis Saenz-Garcia, Normanda Souza-Melo, Juliana Severo Miranda, Beatriz Borges, Lisandro A. Pacheco-Lugo, Jose M. Quintero-Solano, Nilmar Moretti, Richard Wheeler, Lia C. Soares-Medeiros, Wanderson D. DaRocha

“…Here we investigated the <i>T. cruzi</i> Kharon ortholog (<i>Tc</i>Kharon) to test if it has orthologous function and thus potential in generating a live attenuated vaccine. …”
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A strategy for identification and characterization of genic mutations using a temperature‐sensitive chlorotic soybean mutant as an example by C. Nathan Hancock, Tetandianocee Germany, Priscilla Redd, Jack Timmons, Jeffery Lipford, Samantha Burns, Sergio Alan Cervantes‐Perez, Marc Libault, Wenhao Shen, Yong‐qiang Charles An, Lisa Kanizay, Melinda Yerka, Wayne A. Parrott

“…Genome sequencing identified 15 candidate genes with mutations likely to result in a loss of function. Amplicon sequencing of a segregating population was then used to narrow the list to a single candidate mutation, a single‐base change in Glyma.07G102300 that disrupts splicing of the second intron. …”
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How and why do participatory women’s groups (PWGs) improve the quality of maternal and child health (MCH) care? A systematic review protocol by Rebecca Evans, Sarah Larkins, Karen Carlisle, Judy Taylor, Robyn Preston, Sam Rannard, Catrina Felton-Busch, Karla Canuto, Michelle Redman-MacLaren, Nalita Nungarrayi Turner, Lee Yeomans, Emma Sanguineti, Megan Passey, Jane Farmer

“…We aim to demonstrate how PWGs function and why PWG interventions contribute to social and health outcomes.Methods and analysis The protocol will follow Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines. …”
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Clinical significance of incidental common bile duct dilatation in children: A 10-year single medical center experience by Wan-Hsin Su, Hsun-Chin Chao, Mi-Chi Chen, Ming-Wei Lai, Chien-Chang Chen, Pai-Jui Yeh

“…We analyzed the patients’ clinical manifestations, laboratory data, diagnosis, underlying diseases, and clinical course. …”
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STAT3 mediates CAF-induced osimertinib resistance via regulating protein secretion in non-small cell lung cancer by Xuchen Fan, Xuchen Fan, Sheng Wu, Sheng Wu, Honglong Wu, Honglong Wu, Yingying Huang, Yingying Huang, Xuhui Tong, Meiling Yu, Meiling Yu, Zhe Liu, Zhe Liu, Zhe Liu

“…Knockdown of STAT3 can block the secretory function of CAF, thereby reversing Osimertinib resistance in lung cancer. …”
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Research on Reactive Power Optimization Strategy under the Intelligent Improvement Model of the Distribution Network by Menglin Yu

“…Finally, by using historical data and an artificial neural network, this paper extracts electrical quantity data such as load power and distributed power output and environmental data such as temperature and wind speed to perform multiagent analysis. …”
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The Effectiveness of Using the Reggio Emilia Approach on the Experimental Science Lesson for Third-Grade Elementary Students by Batool Sabzeh, Farangis Ghalavand, Seyedamir Ghasemtabar

“…The experimental group was inspired by the Reggio Emilia approach and the control group was trained with the usual method for 15 sessions. Data collection was done using a researcher-made test of the science lesson and functional checklist. …”
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Multi-omics insights into antioxidant and immune responses in Penaeus monodon under ammonia-N, low salinity, and combined stress by Yundong Li, Sheng Huang, Song Jiang, Lishi Yang, Jianhua Huang, Qibin Yang, Ziyi Jiang, Jianzhi Shi, Zhenhua Ma, Erchao Li, Falin Zhou

“…A comprehensive analysis further indicated that the combined stressors of ammonia nitrogen and salinity exert a synergistic effect on the immune function and physiological homeostasis of shrimp by modulating antioxidant metabolic pathways and gut microbial communities. …”
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SMC4 Promotes Prostate Cancer Cell Proliferation and Metastasis via the Rheb/mTOR Pathway by Wei Zhang, Siyuan Qin, Xiaokang Li, Ming Chang, Tianzi Wei, Xin Huang, Haibo Tong, Xia Guo, Yi Lu, Jian Zhang

“…To investigate the function of SMC4, the SMC4 gene is knocked down in RM1‐LM cells, a highly metastatic cell clone is developed, using the CRISPR/Cas9 system. …”
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Polyethylene terephthalate microplastics affect gut microbiota distribution and intestinal damage in mice by Xiangying Sun, Yin Zhuang, Yubang Wang, Zhenbo Zhang, Lihui An, Qiujin Xu

“…Moreover, PET-MPs exposure increased mRNA expression levels of colonic mucus secretion related and barrier function related genes, indicating intestinal mucus secretion and barrier integrity dysfunction, which was consistent with the results of histopathological results. …”
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A study on neutrosophic $$\mathscr {T}_{\textrm{1k}}$$ -semantic segmentation for iris image recognition with Gaussian and Poisson noises by Vinoth Dhatchinamoorthy, Ezhilmaran Devarasan, Asima Razzaque, Saima Noor

“…An experimental set of biometric iris data will be the main focus of the experiment. The analysis employs real-time iris image data. …”
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Trade credit management in wholesale companies based on statistical methods by E. V. Ermakova

“…In the paper, the discriminant analysis was applied to make the decision. The discriminant functions allow choosing such a period of delay that will be broken with the least probability by the customer with certain financial and non-financial characteristics. …”
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