Evaluation of Simulated Weightlessness Model of Hindlimb Unloading Miniature Pigs and Their Tissue Damage by TU Yingxin, JI Yilan, WANG Fei, YANG Dongming, WANG Dongdong, SUN Zhixin, DAI Yuexin, WANG Yanji, KAN Guanghan, WU Bin, ZHAO Deming, YANG Lifeng

“…The experimental group was fixed using customized metal cages, with canvas slings suspending their hind limbs off the ground, and the body positioned at a -20° angle relative to the ground to simulate unloading for 30 days (24 hours a day). Data on body weight, blood volume, and blood biochemistry indicators were collected at different time points for statistical analysis of basic physiological changes. …”
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Trends in the epidemiology of chronic kidney disease in patients with diabetes in Russian Federation according to the Federal diabetes register (2010–2022) by M. S. Shamkhalova, O. K. Vikulova, A. V. Zheleznyakova, M. A. Isakov, M. V. Shestakova, I. I. Dedov, N. G. Mokrysheva

“…The incidence of new CKD cases was 153.3→106.3/10 000 adult patients in T1, and 64.3→212.8/10 000 adult patients in T2. The analysis of the distribution by CKD stage indicates improved diagnosis of the complication. …”
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Development and Validation of a Risk Prediction Model Based on Inflammatory and Nutritional Composite Indicators for Posthepatectomy Liver Failure Following Radical Resection of He... by Li J, Chen M, Cai W, Yin D

“…The predictive performance of the nomogram was evaluated using receiver operating characteristic (ROC) curve analysis, calibration curve assessment, and decision curve analysis (DCA).Results: AAPR, ALBI, GAR, LMR, PNI, INR, APTT, and TT are independent factors associated with PHLF in patients with hepatocellular carcinoma. …”
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Diagnostic value of NLR and PLR for peritoneal dialysis-related infection by FANG Wei-wei, LIU Gui-ling, LI Qing-gen, ZHAO Wen-man, CHEN Xiao-li, LI Dan-dan

“…Objective To investigate the diagnostic and predictive value of peripheral blood neutrophil to lymphocyte ratio(NLR) and platelet to lymphocyte ratio(PLR) for peritoneal dialysis(PD)-related infection. Methods Clinical data of 71 PD patients complicated with PD related infections and 102 maintenance PD patient hospitalized in the same period were retrospectively analyzed for evaluation of peritoneal function and dialysis adequacy. …”
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P21 activated kinase 6: a promising tool for predicting small cell lung cancer diagnosis and treatment response by Simei Chen, Kexin Han, Yinyi Chen, Liping Wei, Xinlu Sun, Yi Luo, Lili Wen, Liming Tan

“…Objective Building upon the established role of P21 Activated Kinase 6 (PAK6) in tumor progression and chemoresistance pathways, we postulate its potential as a dual-function biomarker for small cell lung cancer (SCLC). …”
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SegmentR: Deep learning for automated segmentation with an R interface by James D. Boyko

“…SegmentR allows users to load images, automatically segment them based on text prompts, and extract regions of interest for downstream analysis. The package includes basic visualization and data processing functions to facilitate interpretation of the results and integration with existing analytical workflows. …”
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Vision-related Quality of Life (VRQOL) and its determinants among the Elderly in rural blocks of Haryana, India by Mona Duggal, Ankita Kankaria, Latika Rohilla, Harashish Jindal, Limalemla Jamir, Parul Chawla Gupta, Debarati Sarkar, Vaibhav Miglani, Akash Kumar, Drishti Sharma, Neha Dahiya, Siddhartha Sharma, Sandeep Grover

“…Categorical data as frequency (%). Bivariate analysis was done using Student t-test or Rank Sum test for continuous variables (for up to 2 groups) and One-Way ANOVA was run for continuous variables (for more than 2 groups). …”
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Changes in the Structure of Tax Revenues of Russian Regions by A. Sh. Kamaletdinov, A. A. Ksenofontov

“…The quantitative analysis is implemented using the statistical processing and data visualization functions of the R programming language. …”
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Risk Factors for Stiffness After Fixation of Tibial Tubercle Fractures: A Multicenter Study From the TITUS Group by Konstantin Brnjoš, MD, O. Folorunsho Edobor-Osula, MD, MPH, John S. Blanco, MD, Lindsay M. Crawford, MD, Dustin A. Greenhill, MD, FAOA, Alexander H. Griffith, BS, Neil K. Kaushal, MD, David M. Kell, BA, Abhi Rashiwala, MD, John A. Schlechter, DO, Evelyn S. Thomas, DO, Haley N. Tornberg, BS, Brendan A. Williams, MD, Neeraj M. Patel, MD, MPH, MBS

“…Persistent stiffness after operative treatment of tibial tubercle fractures (TTFs) can inhibit functional recovery and interfere with activities of daily living. …”
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TRIM56 Modulates YBX1 Degradation to Ameliorate ZBP1‐Mediated Neuronal PANoptosis in Spinal Cord Injury by Junsheng Lou, Yiting Mao, Wu Jiang, Honghao Shen, Yunpeng Fan, Qing Yu, Conghui Zhou, Ziyao Wei, Kailiang Zhou, Mengran Jin, Junsong Wu

“…Taken together, these findings reveal a novel function of YBX1 in regulating ZBP1‐mediated PANoptosis in the pathogenesis of SCI and verified that TRIM56 functions as an endogenous inhibitor to promote the ubiquitin‐proteasomal degradation of YBX1, providing new insights into SCI treatment strategies.…”
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Prion protein regulates invasiveness in glioblastoma stem cells by Mariana B. Prado, Bárbara P. Coelho, Rebeca P. Iglesia, Rodrigo N. Alves, Jacqueline M. Boccacino, Camila F. L. Fernandes, Maria Isabel Melo-Escobar, Shamini Ayyadhury, Mario C. Cruz, Tiago G. Santos, Flávio H. Beraldo, Jue Fan, Frederico M. Ferreira, Helder I. Nakaya, Marco A. M. Prado, Vania F. Prado, Martin L. Duennwald, Marilene H. Lopes

“…Single-cell RNA sequencing analysis of data from patient tumors from The Cancer Genome Atlas (TCGA) and the Broad Institute of Single-Cell Data Portal were used to evaluate the correspondence between our in vitro results and patient samples. …”
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Identification of DNA Methylation Differences in Pituitary Tissues of Sichuan White Geese Using Whole-Genome Bisulfite Sequencing (WGBS) by Lin Ma, Xianzhi Zhao, Guoda A, Tongtong Song, Meng Wu, Zhihao Yan, Min Xiao, Wenbo Jiang, Yixiao Gao, Haiwei Wang, Zhuping Chen, Keshan Zhang, Jiajia Xue, Yi Luo, Chao Wang, Youhui Xie, Ying Chen, Guangliang Gao, Qigui Wang

“…Integrated GO and KEGG enrichment analysis conducted to explore the role of regulatory networks of epigenetic modification on egg-laying traits in Sichuan White geese identified multiple metabolic pathways associated with egg-laying traits (promoting egg transport, ovulation, and yolk protein synthesis and secretion), thus providing a basis for subsequent functional verification.…”
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Mitochondrial proteins and congenital birth defect risk: a mendelian randomization study by Xin-yu Li, Da-tao Li, Yi-yuan Li, Zhi-cheng Xu, Qun Zhang, Xia Chen, Feng Xu, Ru-hong Zhang

“…Methods Summary statistics data on congenital birth defects were obtained from the FinnGen consortium. …”
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Protocol for an outcome assessor-blinded pilot randomised controlled trial of an ion-exchange water softener for the prevention of atopic eczema in neonates, with an embedded mecha... by Joanne R Chalmers, Sanja Kezic, Zarif K Jabbar-Lopez, Nikeeta Gurung, Danielle Greenblatt, Annette Briley, Kim Suzanne Thomas, Tony Frost, John E A Common, Heidi H Kong, Julie A Segre, Simon Danby, Michael J Cork, Janet L Peacock, Carsten Flohr

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Virtual reality-assisted rehabilitation for postoperative C5 palsy: a pilot exploratory randomized controlled trial by Kyung-Soo Suk, Jinyoung Park, Taeyeon Choi, Byung Ho Lee, Yongjin Ahn, Sunung Yun, Si Young Park, Hak Sun Kim, Seoung-Hwan Moon, Ji-Won Kwon

“…Ten patients (VR = 4, Control = 6) completed the study. Results Final analysis included data from 4 patients in the VR group and 6 patients in the control group. …”
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Upregulation of long noncoding RNA zinc finger antisense 1 enhances epithelial–mesenchymal transition in vitro and predicts poor prognosis in glioma by Qiao-Li Lv, Shu-Hui Chen, Xue Zhang, Bao Sun, Lei Hu, Qiang Qu, Yuan-Tao Huang, Gui-Hua Wang, Yan-Ling Liu, Ying-Ying Zhang, Hong-Hao Zhou

“…Zinc finger antisense 1 is a novel long noncoding RNA whose clinical significance, biological function, and underlying mechanism are still undetermined in glioma. …”
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Chitinase-1 inhibition attenuates metabolic dysregulation and restores homeostasis in MASH animal models by Katarzyna Drzewicka, Katarzyna M. Głuchowska, Michal Mlącki, Bartłomiej Hofman, Irina Tuszyńska, Tristram A. J. Ryan, Katarzyna Piwowar, Bartosz Wilczyński, Dorota Dymkowska, Marcin M. Grzybowski, Barbara Dymek, Tomasz Rejczak, Kamil Lisiecki, Adam Gołębiowski, Adam Jagielski, Angelika Muchowicz, Dylan Ryan, Krzysztof Zabłocki, Luke A. J. O’Neill, Zbigniew Zasłona

“…In addition to reducing inflammation and fibrosis observed in the rat model, RNA-Seq demonstrated that OATD-01 regulated key metabolic processes such as acetyl-CoA metabolism, triglyceride metabolism, cholesterol synthesis, cholesterol flux, and glycolysis. Using functional assay performed on bone marrow-derived macrophages (BMDMs) we demonstrated that both genetic and pharmacological inactivation of CHIT1 resulted in inhibition of glucose uptake. …”
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Beyond the Diagnosis: Lived Experiences of Persons with Spinal Cord Injury in a Selected Town in Ghana by Abdul-Ganiyu Fuseini, Patience Aniteye, Afizu Alhassan

“…The data was analyzed concurrently with data collection, using thematic content analysis. …”
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Exploring the ripple effects of an Australian hospital redevelopment: a protocol for a longitudinal, mixed-methods study by Jeffrey Braithwaite, Kate Churruca, Louise A Ellis, Chiara Pomare, Janet C Long, Brett Gardiner

“…How hospital redevelopment influences the wider context of the hospital will be assessed in six domains: expectations and reflections of hospital redevelopment, organisational culture, staff interactions, staff well-being, efficiency of care delivery and patient experience. Methods of data collection include a hospital-wide staff survey, semistructured interviews, a network survey, a patient experience survey, analysis of routinely collected hospital data and observations. …”
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The Influence of School Principals' Learning Leadership and School Climate on Teacher Performance by A. Aulia Reski Novianti Alnisyar, Fatmiati Nur

“…Data analysis used multiple regression analysis, partial analysis, simultaneous analysis and coefficient of determination analysis. …”
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