Drug related problems and associated factors among thyroid disorder patients in Northwest Ethiopia by Fisseha Nigussie Dagnew, Samuel Agegnew Wondm, Melak Erara Mengistu, Samuel Berihun Dagnew, Tilaye Arega Moges, Gashaw Binega Mekonnen

“…The identified drug-related problem was recorded and classified using Cipolle et al. 2012, adverse drug reactions were assessed by using the Naranjo algorithm of adverse drug reaction probability scale, and Up-to-date was used for the drug-drug interaction checker. The collected data was cleared, entered into epidata, checked for correctness, and exported to STATA version 17 for analysis. …”
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Peculiarities of synthesis and bactericidal properties of nanosilver in colloidal solutions, SiO₂ films and in the textile structure: a review by A. M. Eremenko, I. S. Petryk, Y. P. Mukha, N. V. Vityuk, N. P. Smirnova, A. D. Rudenko

“… The aim of this work is a comparative analysis of the biocidal efficiency of Ag nanoparticles (NPs) in the colloidal state, in the structure of films and dispersions of SiO2 and in the composition of textile fabrics, dependent on the method of synthesis, based on literature data and on own researches. …”
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Efficacy and safety of D-TACE followed by D-RFA for unresectable large hepatocellular carcinoma by Qingqing Pang, Wenping Luo, Shaojun Chen, Hua Zhou, Riguang Zhang, Yueyong Li, Jianbo Zhao, Chunwang Yuan, Guodong Wang

“…This combination treatment provides a useful reference value for the exploration of new treatment modes for advanced liver cancer, but the long-term efficacy evaluation requires multi-center, large-sample clinical studies, and continuous follow-up data analysis.…”
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Study of correlation between calcification regulatory factors and cognitive impairment in maintenance hemodialysis patients by Luo Jie-yu, Ding Zi-jun, Zhang Chun-jiang, Jin Xin, Hao Wen-juan, Zhao Dan

“…The general and laboratory data of the patients were collected. Cognitive function was evaluated with the Chinese version of Montreal Cognitive Assessment Scale （C-MoCA）. …”
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Electrocardiographic findings for predicting the left anterior descending artery chronic total occlusion in patients with inferior ST-segment elevation myocardial infarction by Xiaobin Zheng, Zhaofu Zhang, Bingqi Yao, Haiyan Wu

“…In patients with inferior STEMI complicated by LAD occlusion without anterior myocardial infarction, cardiac function is poorer. The ST-segment deviation between the leads V4 and III, and the duration of QRS in the lead V4, can aid in diagnosis.…”
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CASSAVA VALUE ADDITION: A CASE STUDY OF CASSAVA-BASED BREAD PRODUCERS IN ONDO STATE, NIGERIA by Similoluwa ADEWOLE, Adegboyega OMOWOLE

“…Data collected were analyzed using descriptive statistics, gross margin analysis and multiple regression analysis. …”
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Super-enhancer-hijacking RBBP7 potentiates metastasis and stemness of breast cancer via recruiting NuRD complex subunit LSD1 by Yuanyin Xi, Ruoding Wang, Man Qu, Qinwen Pan, Minghao Wang, Xiang Ai, Zihan Sun, Chao Zhang, Peng Tang, Jun Jiang, Ying Hu

“…CCK8, colony formation, and Transwell assays were utilized to estimate the oncogenic functions of RBBP7. The ChIP-qPCR and dual-luciferase reporter assays were used to investigate the epigenetic mechanisms of RBBP7. …”
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Single-cell ligand–receptor profiling reveals an immunotherapy-responsive subtype and prognostic signature in triple-negative breast cancer by Chuanzhi Chen, Jiahui Qi, Weichao Lin, Chunlan Fu, Xin Jin

“…Among the LR pairs, the CXCL9–CXCR3 axis was identified as a key factor in immune cell recruitment and anti-tumor responses. Functionally, silencing the CXCL9/CXCR3 axis significantly diminished the proliferation, colony formation, and migratory capabilities of MDA-MB-231 cells. …”
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Real-world clinical determinants of alcohol dependence in outpatients with bipolar disorder: a multicenter treatment survey for bipolar disorder in psychiatric outpatient clinics w... by Keita Tokumitsu, Norio Sugawara, Naoto Adachi, Yukihisa Kubota, Yoichiro Watanabe, Kazuhira Miki, Takaharu Azekawa, Koji Edagawa, Eiichi Katsumoto, Seiji Hongo, Eiichiro Goto, Hitoshi Ueda, Masaki Kato, Masaki Kato, Reiji Yoshimura, Reiji Yoshimura, Atsuo Nakagawa, Atsuo Nakagawa, Toshiaki Kikuchi, Toshiaki Kikuchi, Takashi Tsuboi, Takashi Tsuboi, Koichiro Watanabe, Koichiro Watanabe, Norio Yasui-Furukori, Norio Yasui-Furukori

“…BackgroundBipolar disorder is a psychiatric disorder characterized by mood swings between manic and depressed states that causes psychosocial problems. Cognitive function deteriorates with each recurrence, making it important to maintain remission through continued treatment. …”
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MS4A7 based metabolic gene signature as a prognostic predictor in lung adenocarcinoma by Yan Jiang, Zhengyu Shu, Lei Cheng, Lei Cheng, Haowei Wang, Taiping He, Liwen Fu, Chao Zhao, Xuefei Li, Weicheng Zeng, Weicheng Zeng

“…Genes with differential expression linked to metabolic pathways were identified, and 20 genes were included to develop a risk signature. Further functional enrichment analysis was conducted to compare the biological pathways activated in high-risk versus low-risk groups. …”
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A comparative study on the application effects of total laparoscopic right-sided colon anastomosis and laparoscopic plus auxiliary incision anastomosis in radical resection of righ... by He Zhiyong, Qi Sheng, Zeng Dong, Zhang Jiancheng

“…[Methods] A retrospective analysis was conducted on the clinical data of 103 patients with RCC who were admitted to our hospital from January 2020 to May 2022. …”
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How does biological age acceleration mediate the associations of obesity with cardiovascular disease? Evidence from international multi-cohort studies by Lin Hu, Jiayuan Li, Zihuan Tang, Peng Gong, Zongqi Chang, Chen Yang, Tianpei Ma, Shuang Jiang, Chunxia Yang, Tao Zhang

“…Methods This international multi-cohort study included participants aged over 45 years with 3 waves longitudinal data from China Health and Retirement Longitudinal Study (CHARLS). …”
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Exploration of the clinical prognostic model of BRCA based on PCAT7 by Zhi Zhang, Chaocheng Xiang, Tong Chen, Aimin Ma, Xu Wang, Jiaying Li, Yixuan Chen, Yixuan Chen, Chengyu Huang, Chengyu Huang, Ting Li, Ting Li, Danmei Wu, Steven Mo, Dequan Li

“…Consequently, investigating the function and prognostic significance of PCAT7 in BRCA has become imperative.MethodsThis study used BRCA data from the Cancer Genome Atlas (TCGA) as a training cohort to evaluate the prognostic potential of PCAT7. …”
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Identification of Driving Factors of Scientific and Technological Innovation in the New Material Industry Based on the Theory of Complex Adaptive System: Taking the Construction of... by Tengfei Ma, Chao Liu

“…Analysis is as follows. The experimental group and the control group are set for comparison, and the data are organized by applying complex adaptive system theory and data analysis methods. …”
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CD4 T cell dynamics shape the immune response to combination oncolytic herpes virus and BRAF inhibitor therapy for melanoma by Victoria Jennings, Kevin Harrington, Hardev Pandha, Alan Melcher, Adel Samson, Fiona Errington-Mais, Victoria Roulstone, Eva Crespo-Rodriguez, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Martin McLaughlin, Malin Pedersen, Richard Vile, Joan Kyula, Jehanne Hassan, Lizzie Appleton, Charleen ML Chan Wah Hak, Gabby Baker, Edward Armstrong, Matthew Chiu, Masahiro Ono

“…In addition to standard FACS analysis, we used the ‘Timer of Cell Kinetics and Activity’ system, which can analyze the temporal dynamics of different T cell subsets. …”
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Efficacy and safety of Neurocognitive Adaptive Training for Depression combined with SSRIs for treating cognitive impairment among patients with late-life depression: a 12-week, ra... by Xiao Wang, Jiaojiao Zhou, Kemeng Zhu, Yida Wang, Xianglin Ma, Li Ren, Chengwei Guo, Zhanjun Zhang, Peng Lu, Qinge Zhang

“…During the 12-week study period, MMRM analysis revealed a significantly greater reduction in cognitive function (as indicated by ADAS-cog total scores) from baseline to post-treatment in the NCAT-D and SSRIs group compared to the SSRIs and Control groups [(F (1,115) = 13.65, least-squares mean difference [95% CI]: −2.77 [− 3.73, − 1.81], p < 0.001)]. …”
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IMPLEMENTATION OF A HYBRID METHOD OF SEARCHING FOR CLOSE OBJECTS, TAKING INTO ACCOUNT THE GENERAL AND ACOUSTIC CHARACTERISTICS by Olga Malyeyeva, Vadym Yesipov, Roman Artiukh, Viktor Kosenko

“…The following tasks are solved: analysis of methods and algorithms used in recommendation systems; development of a hybrid method of forming recommendations on the principle of double organization; determination of the main functions and architecture of the system of formation of musical recommendations; testing of calculation algorithms and search methods in the system for analysis of similarity of musical recommendations. …”
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Non-canonical activation of MAPK signaling by the lncRNA ASH1L-AS1-encoded microprotein APPLE through inhibition of PP1/PP2A-mediated ERK1/2 dephosphorylation in hepatocellular car... by Lei Zhao, Ke Si, Shenjian Luo, Lantian Zhang, Shuai Mao, Wenliang Zhang

“…The functional role of ASH1L-AS1 and its encoded microprotein APPLE was explored through in vitro and in vivo assays, such as CCK-8, EdU incorporation, wound healing, Transwell migration and invasion, and xenograft tumor models. …”
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Economic feasibility, perception of farmers, and environmental sustainability index of sorghum-eucalyptus agroforestry by . Komalawati, S. Hidayat, R.H. Praptana, M.D. Pertiwi, A.S. Romdon, Y. Hidayat, R.P. Ramadhan, D. Yuniati, . Saptana, . Syahyuti, N. Khaririyatun, S. Ika, R.K. Jatuningtyas, . Subiharta, R.N. Hayati, S. Sudarto, M.P. Yufdy, B. Nuryanto, A. Prasetyo

“…The data collected were analyzed using the revenue-cost ratio, Likert scale, and scoring formulation, as well as multi-dimensional scale method. …”
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A genome-wide base-editing screen uncovers a pivotal role of paxillin δ ubiquitination in influenza virus infection by Jiamei Guo, Zhuo Zhou, Ruining Li, Zhifang Xing, Lei Zhang, Shiyi Zhao, Wensheng Wei, Jianwei Wang, Tao Deng

“…Here, we leverage a genome-wide CRISPR base-editing screen to identify functional lysine residues in host factors required for influenza A virus (IAV) replication. …”
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