Assessing the prognostic and therapeutic value of cuproptosis-related genes in colon adenocarcinoma patients by Zhanhui Ye, Yixian Song, Mengqing Zhu, Fuying Zheng, Wenjie Qin, Wenjie Qin, Xue Li, Pei Wang, Zihua Li, Kequan Chen, Aimin Li

“…Using the Weighted Gene Co-expression Network Analysis (WGCNA) method, we identified the gene module most strongly linked to cuproptosis and conducted functional enrichment analysis to explore the roles of genes within this module in COAD tumorigenesis. …”
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A non-invasive method for screening mitochondrial diabetes by Hangyu Fang, Hangyu Fang, Xiaoe Li, Shuping Wang, Mei Zhang, Victor Wei Zhang, Chao Xu, Chao Xu, Chao Xu, Chao Xu, Chao Xu, Chao Xu, Chao Xu

“…Additionally, we summarized the clinical phenotypes of patients who tested positive and compared the clinical manifestations between MDM and non-MDM patients using statistical analysis, providing a diagnostic foundation for clinicians.ResultsWe collected data from a total of 478 patients and identified 16 cases of m.3243A>G mutation-positive patients by collecting oral exfoliated cell samples for PCR testing, yielding a positivity rate of 3.35% and an asymptomatic carrier rate of 0.84%. …”
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A RAD51 assay feasible in routine tumor samples calls PARP inhibitor response beyond BRCA mutation by Marta Castroviejo‐Bermejo, Cristina Cruz, Alba Llop‐Guevara, Sara Gutiérrez‐Enríquez, Mandy Ducy, Yasir Hussein Ibrahim, Albert Gris‐Oliver, Benedetta Pellegrino, Alejandra Bruna, Marta Guzmán, Olga Rodríguez, Judit Grueso, Sandra Bonache, Alejandro Moles‐Fernández, Guillermo Villacampa, Cristina Viaplana, Patricia Gómez, Maria Vidal, Vicente Peg, Xavier Serres‐Créixams, Graham Dellaire, Jacques Simard, Paolo Nuciforo, Isabel T Rubio, Rodrigo Dienstmann, J Carl Barrett, Carlos Caldas, José Baselga, Cristina Saura, Javier Cortés, Olivier Déas, Jos Jonkers, Jean‐Yves Masson, Stefano Cairo, Jean‐Gabriel Judde, Mark J O'Connor, Orland Díez, Judith Balmaña, Violeta Serra

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Neural correlates of device-based sleep characteristics in adolescents by Qing Ma, Barbara J. Sahakian, Bei Zhang, Zeyu Li, Jin-Tai Yu, Fei Li, Jianfeng Feng, Wei Cheng

“…We applied sparse canonical correlation analysis (sCCA) to data from 3,222 adolescents in the Adolescent Brain Cognitive Development (ABCD) study, integrating sleep characteristics with multimodal imaging. …”
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Prolonged venous transit is associated with worse neurological recovery in successfully reperfused large vessel strokes by Janet Mei, Hamza Adel Salim, Dhairya A. Lakhani, Licia Luna, Aneri Balar, Mona Shahriari, Nathan Z. Hyson, Francis Deng, Adam A. Dmytriw, Adrien Guenego, Vaibhav Vagal, Victor C. Urrutia, Elisabeth B. Marsh, Hanzhang Lu, Risheng Xu, Rich Leigh, Dylan Wolman, Gaurang Shah, Benjamin Pulli, Kambiz Nael, Gregory W. Albers, Max Wintermark, Jeremy J. Heit, Tobias D. Faizy, Argye E. Hillis, Raf Llinas, Vivek Yedavalli

“…Methods We performed a retrospective analysis of prospectively collected data from consecutive adult AIS‐LVO patients with successful reperfusion (modified Thrombolysis in Cerebral Infarction 2b/2c/3). …”
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Potato Peels as an Adsorbent for Heavy Metals from Aqueous Solutions: Eco-Structuring of a Green Adsorbent Operating Plackett–Burman Design by Marwa El-Azazy, Ahmed S. El-Shafie, Ahmed A. Issa, Maetha Al-Sulaiti, Jawaher Al-Yafie, Basem Shomar, Khalid Al-Saad

“…The Pareto chart of standardized effects shows that the most influential factor is the HMC. These data were confirmed by analysis of variance (ANOVA). …”
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Essential Trace Elements in Three Species of Dolphins Stranded in the Croatian Part of the Adriatic Sea from 1995 to 2013 by Maja Đokić, Nina Bilandžić, Marija Sedak, Tomislav Bolanča, Tomislav Gomerčić, Martina Đuras, Miroslav Benić

“…Trace elements are widely distributed in the environment and are considered essential when their deficiency leads to impaired biological function. This study aimed to quantify concentrations of two essential trace elements—copper (Cu) and zinc (Zn)—in the tissues of three toothed whale (<i>Odontoceti</i>) species: bottlenose (<i>Tursiops truncatus</i>), striped (<i>Stenella coeruleoalba</i>), and Risso’s dolphins (<i>Grampus griseus</i>) found deceased along the Croatian coast of the Adriatic Sea between 1995 and 2013. …”
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The unexplored mechanism of antitumoral effect of pirfenidone in melanoma cells by Melissa Marchese, Gilda La Regina, Rachele Amato, Gianmarco Bertoni, Jessica Ruzzolini, Daniele Martinucci, Laura Papucci, Silvia Peppicelli, Francesca Bianchini

“…Recently, it has been suggested that PFD may function as furin convertase enzyme inhibitor. Furin is involved in many physiological and pathological processes such as BRAF oncogene activation. …”
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A novel anti-reflux esophagogastric anastomosis in totally laparoscopic proximal gastrectomy: Hao’s esophagogastrostomy by fissure technique (HEFT) by Ze-Qin Wang, Wen-Liang Cui, Yan-Feng Zhu, Ming-Ye Ma, Jian Wang, Zi-Hao Wang, Ya-Ping Wang, Jun Hong, Han-Kun Hao

“…Methods A retrospective analysis was conducted on the clinical data of 11 consecutive cases that underwent totally laparoscopic proximal gastrectomy with HEFT at Huashan Hospital, Fudan University from September 2021 to January 2024. …”
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A preliminary study on digital quantification of ocular attributes in cattle as potential non-invasive indicators of anemia by Mushtaq Hussain Lashari, Anna Abdullah, Fouzia Nazir, Asma Iqbal, Muhammad Abrar Afzal, Umer Farooq, Musadiq Idris, Musarrat Abbas Khan, Faisal Shahzad, Mahad Azam, Khawar Ali Shahzad, Dalia Fouad, Farid Shokry Ataya, Shagufta Nasreen

“…The palpebral conjunctiva color chart developed through this preliminary data could function as an on-field point-of-care testing (POCT) tool to predict Hb and PCV levels in cattle.…”
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Nutritional Status and Lung Cavity in Pulmonary Tuberculosis Patient by Christi Giovani Anggasta Hanafi, Fariz Nurwidya, Wiji Lestari, Heidy Agustin, Shaogi Syam

“…These findings might indicate how malnutrition impaired the immune function in PTB patients.…”
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Correlation between mitral annular plane systolic excursion (MAPSE) at different degrees of ejection fraction in patients with diabetes mellitus by Muhammad Rido, Khalid Saleh, A. Makbul Aman, Syakib Bakri, Haerani Rasyid, Andi Alfian Zainuddin

“…Diabetic cardiomyopathy is characterized by myocardial structure and function abnormality in the absence of other cardiovascular risk factors. …”
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Empowering Retail Through Advanced Consumer Product Recognition Using Aquila Optimization Algorithm With Deep Learning by Mohammed Alghamdi, Hanan Abdullah Mengash, Mohammed Aljebreen, Mohammed Maray, Abdulbasit A. Darem, Ahmed S. Salama

“…The comprehension of automatic product identification becomes of major importance for both social and economic improvement since it is more reliable and time-consuming than manual function. Product detection through images is a complex task in the domain of CV. …”
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Negative Regulation of <i>GmNAC35</i> by miR164 Enhances Drought Tolerance in Soybean by Wentao Hu, Man Zhang, Jie Lu, Miaomiao Zhang, Reqing He, Youlin Zhu, Dong Wang, Liyun Jiang

“…The miR164 family is highly conserved across plant species and has been shown to participate in drought responses in a range of plants, yet the function of miR164 in soybean remains unclear. In this study, we identified <i>GmNAC35</i> as a direct target of miR164 through published degradome sequencing data and 5′ RLM-RACE assays. …”
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Peanut thresholds in peanut‐allergic children are related to dietary composition by Daisy Luiten, Maarten Biezeveld, Olga vanDoorn, Hanae Riady, Ming Yang, Femke Bergsma, Atie van derPlas, Kim Brand, Nicolette Arends, Annette deBruin, Jeanne deVries, Tim deMeij, Berber Vlieg‐Boerstra

“…We hypothesized that diet composition can partly explain this variation in thresholds, as nutrients and foods influence the intestinal barrier function and microbiota. Aim to explore the relationship between the threshold levels for peanut and nutritional intake and gut microbial composition in peanut‐allergic children. …”
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Interpretation services used for non-English language speaking patients with head and neck cancer: Findings from a tertiary London cancer centre by Maesaya Chartkul, Florence Cook, Roganie Govender

“…Background: Treatment for head and neck cancer (HNC) can lead to profound changes in swallowing function and nutrition. UK HNC standards recommend informational counselling is provided pre-treatment by the dietitian and speech and language therapist (SLT). …”
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Spiritual Leadership Enhances Caring Behaviour: The Mediating Role of Calling by Sang Ayu Ketut Candrawati, Ni Kadek Ayu Sriani, Putu Gede Subhaktiyasa, Ni Komang Sukra Andini, Ni Luh Nova Dilisca Dwi Putri, Ni Ketut Citrawati, Megah Andriany

“…Calling proved to mediate the effects of spiritual leadership on caring behaviour (t=3.145, p=0.002), while membership could not function as a mediator (t=1.197, p=0.231). Conclusion: This study emphasizes the importance of spiritual leadership in nursing care, particularly in enhancing nurses’ caring behaviours. …”
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“Discharge doesn’t mean the end”: Exploring success in discharge to community self-management for young adults living with chronic pain: A qualitative study by Souraiya Kassam, Emi Wong, Marysa Thompson, Todd Tran, Rachael Bosma, Sarah Sheffe

“…Inadequate discharge planning may increase the unique difficulties YAs face in self-management, which may lead to adverse health outcomes, suboptimal discharge, and a need to reaccess care.Aims The purpose of this qualitative study is to explore how YAs with chronic pain define a successful discharge transition from a health service delivery model of specialized chronic pain services setting to self-management in a community setting (i.e. primary care) and contextual factors that promote discharge success.Methods This qualitative study included young adults with chronic pain. Data were obtained through semistructured interviews, which were transcribed verbatim and analyzed using inductive content analysis.Results Ten participants identified that successful discharge includes the following considerations: (1) acknowledging the tension between moving forward and looking back, (2) a collaborative discharge process, and (3) the need for ongoing, relevant resources and support.Conclusion This study provides a deeper understanding of how YAs with chronic pain characterize success in the discharge transition from specialized chronic pain services to community self-management. …”
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Radial growth and climate responses of healthy versus decayed subalpine conifer trees in the southeastern Qinghai-Tibetan Plateau by Lingzhuo Luo, Wenzhi Wang, Zhehong Wu, Yong Su

“…Yet, it is questionable whether heartwood-decayed trees can still function on par with healthy trees. Here, using tree ring data, we established basal area increment (BAI) series of healthy and heartwood-decayed fir trees at four sites (Abies spectabilis in Bomi; A. georgei Orr in Deqin as well as the Sygera Mountain; A. fabri Craib in Yajiageng) in the southeastern Qinghai-Tibetan Plateau (QTP). …”
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Clinical features and outcomes of pseudolithiasis induced by ceftriaxone in Chinese children: a single-center observational study by Chen Jin, Chen Jin, Wen-Li Xiu, Wen-Li Xiu, Yao Liu, Yao Liu, Xi-Wei Hao, Qian Dong, Qian Dong

“…Patients with PL also had higher rates of digestive and neurological infections (both p &lt; 0.001). Serum analysis revealed distinct liver and kidney function markers in the PL group, including lower levels of total bile acids, adenosine deaminase, and lactate dehydrogenase, and higher creatinine levels (all p &lt; 0.05). …”
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