Activation of eIF2α-ATF4 by endoplasmic reticulum-mitochondria coupling stress enhances COX2 expression and MSC-based therapeutic efficacy for rheumatoid arthritis by Jiaqing Liu, Xing Zhang, Xiangge Zhao, Jinyi Ren, Huina Huang, Cheng Zhang, Xianmei Chen, Weiping Li, Jing Wei, Xia Li

“…However, the loss of secretory function following cell delivery has significantly restricted its clinical application. …”
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Study on the correlation of nutritional status with clinical and pathological characteristics of patients with IgA nephropathy by Du Yan-bin, Du Yan-ling, Li Huan, Yuan Zu-jun

“…ObjectiveTo explore the correlation of serum total protein， albumin， and prognostic nutritional index （PNI） with the clinical and pathological characteristics of IgA nephropathy （IgAN）， and to evaluate the impact of these nutritional indicators on the severity of IgAN.MethodsA total of 218 IgAN patients who were treated at Nephrology Department of Nanchong Central Hospital from January 1， 2019， to April 1， 2024 were included in this study. Baseline data， blood biochemistry results， nutritional and renal function indicators were collected from the patients. …”
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Cloning of the Ajcaspase-8 Gene and Its Temporal Expression and Distribution Analyses During Embryonic Development in the Sea Cucumber Apostichopus japonicus by Xiaojing ZHANG, Chanchan ZHANG, Deyou MA, Jiayi LIANG, Meizhu YAO, Ziji LI

“…Furthermore, a death receptor domain and two subunits (P20 and P10) were present in Ajcaspase-8 deduced protein, which acted as key motifs to perform the function of an initiator caspase in the apoptosis pathway. …”
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Neuronal expression of CaMKⅡ and BDNF isoforms in mice with cognitive dysfunction induced by repetitive mild traumatic brain injury by LIU Dianqing, LIU Dianqing, LI Yun, LI Yun, ZHANG Jietao

“…From the 30th day after the end of modeling， Morris water maze test was applied to evaluate the spatial learning and memory abilities， and the relative data was evaluate for correlation analysis. According to the taxonomy of cognitive levels， the model group was further stratified into high-， medium- and low-performance groups. …”
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U-Net-based VGG19 model for improved facial expression recognition by Xiaohu ZHAO, Jingyi ZHANG, Mingzhi JIAO, Lixun XIE, Lanfei WANG, Weiqing SUN, Di ZHANG

“…The innovation of the SEAttention module lies in replacing the original activation function with the Mish activation function, which can dynamically adjust the weights of different channels to enhance performance. …”
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Glycemic variability and diabetic cardiac autonomic neuropathy by A.A. Serhiyenko, T.V. Tsaryk, Y.I. Pavlovskiy, V.A. Serhiyenko

“…The article provides an analysis of literature data on the impact of glycemic variability (GV) on diabetic CAN development. …”
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Clinical and pathological features of idiopathic membranous nephropathy patients combined with hyperuricemia by ZHAO Li, JIN Juan, GONG Jian-guang, LI Yi-qiao, HE Qiang

“…Methods A retrospective analysis was conducted by collecting 125 cases of IMN diagnosed by renal biopsy in our hospital between January 2014 and January 2017. …”
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Distinctive Contribution of Sound Spectral Features in Enhancing Vibration-Based Multi-Component Fault Classification Under Non-Stationary Speed Conditions by S. Sowmya, M. Saimurugan, Naveen Venkatesh

“…To begin with, speed synchronizing instantaneous frequency (IF) with two signal envelopes of vibration signals are individually fed to the machine learning (ML) classifier, such as Decision Tree (DT), Support Vector Machine-Radial Basis Function (SVM-RBF), and Artificial Neural Network (ANN), to verify the model performance. …”
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Non-linear relationship between calf circumference and global cognition in Chinese population: a cross-sectional study of 12,102 Chinese older adults by Yuting Nie, Cheng Gu, Ruipeng Wu, Fulin Gao, Le Zhang, Yamin Zhang

“…Notably, among women with CC values <32 cm, a significant positive correlation was observed between CC and overall cognitive function. Conversely, for women with CC ≥ 32 cm, no significant association was found between CC and cognitive performance. …”
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Immunohistochemical assessment of epidermal growth factor receptor and prohibitin expression in “post-COVID” placentas: results of a comparative cross-sectional study by G.S. Manasova, Y.O. Stasii

“…Specific proteomic studies of the function of the placenta are insufficient. Objective of the study: to study the perinatal outcomes of pregnancy and histopathological features of the placenta and the expression of epidermal growth factor receptors (EFGR) and prohibitin (PHB) in the placenta in pregnant women with COVID-19 infection in comparison with data in a group of healthy pregnant women without a COVID-19 history. …”
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METTL14-mediated m6A modification upregulates HOXB13 expression to activate NF-κB and exacerbate cervical cancer progression by Qian Li, Na Zhao, Xuejing Ding, Jufen Zhao

“…The expression of METTL14 was detected by RT-qPCR and western blot. Cell function was assayed by cell counting kit-8 (CCK-8) assay and flow cytometry analysis. …”
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Effectiveness of Educational Program on Nurse's Knowledge Concerning Management of Cardiogenic Shock at AL-Mosul Teaching Hospitals by Hakema S. Hassan, Ali M F. Hussein

“…Reliability of instrument tools was determined through the use of test and retest and the instrument validity was determined through a panel of experts. The analysis of data was performed through the application of description statistic (Frequencies, Percentages, and cumulative percent, Mean of Score, Standard Deviation, Relative Sufficiency) and Inferential statistical (Chi-Square test, Fisher Exact Probability test to present the differences between the study and control groups). …”
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Predictors of 30-day mortality in major lower limb amputations: insights from a five-year retrospective study in a South Asian LMIC by Mohammad Zakriya, Zia Ur Rehman, Muhammad Anees, Hafsa Shaikh, Adnan Qadir Memon, Nadeem Ahmed Siddiqui, Fareed Shaikh

“…These findings emphasize the need for proactive identification of high-risk individuals, optimization of comorbid conditions, especially renal function, and strengthening perioperative infection control practices to improve patient outcomes in resource-limited settings.…”
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The impact of clopidogrel combined with aspirin or aspirin alone on prognosis and adverse events in patients undergoing coronary artery bypass grafting in the first month after sur... by Haiming Li, Hui Hu, Jingxing Li, Chengxiong Gu, Bo Li

“…Graft patency, platelet function, and postoperative adverse events were evaluated, with statistical significance set at a P-value < 0.05. …”
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Application of internal fixator system for anterior pelvic ring with simultaneous application of sacroiliac screw internal fixation of the posterior pelvic ring in Tile C-type unst... by Liu Zhongbing, Zou Guoyou

“…The subjects (89 of them in total) were recruited among patients with TCUPT from December 2020 to December 2023. A retrospective analysis of the subjects’ data was performed, after which the subjects were divided into two groups based on different therapeutic regimens applied: group A (INFIX system for the APR + SS IN-FIX of the PPR, n = 46) and group B (external fixator for the APR + SS INFIX of the PPR, n = 43). …”
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Nutrigenomic and Nutritional Analyses Reveal the Effects of Pelleted Feeds on Asian Seabass (Lates calcarifer). by Si Yan Ngoh, Daniel Tan, Xueyan Shen, Purushothaman Kathiresan, Junhui Jiang, Woei Chang Liew, Natascha May Thevasagayam, Hsiao Yuen Kwan, Jolly M Saju, Sridatta R S Prakki, Chin Heng Goh, Hong Ching Wong, Tai Teck Chan, Miklós Mézes, László Orbán

“…Significant enrichment of genes with growth-related function tallied with the morphological data measured. …”
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Drug induced liver injury in HIV patients on dolutegravir based antiretroviral therapy regimens in Wolaita Sodo comprehensive specialized hospital by Firew Abraham, Alemayehu Toma, Tamrat Balcha, Bereket Molla Tigabu

“…Kaplan Maier survival analysis was used to estimate mean survival function. …”
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Validation of the "Six Step Spot Test" for gait among patients with multiple sclerosis in Brazil Validação do teste de marcha "Six Step Spot Test" em pacientes com esclerose múltip... by Karina Pavan, Charles Peter Tilbery, Sergio Lianza, Bruna Eriko Matsuda Marangoni

“…According to the statistical analysis on the data in this study, the SSST is a valid, reliable and reproducible tool for use in the Brazilian MS patient population.…”
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Evaluation of the user experience for a point of care molecular test for causes of vaginitis by Barbara Van Der Pol, Rebecca Lillis, Irving Nachamkin, Stephen Young, LaShonda Crane, Jacqueline Brown, R. Lamar Parker, Alice Weissfeld, Xiaohong Liu, Christina Huang, Aarthi Raman

“…Methods A secondary analysis of data was collected from test operators at POC testing sites where the Xpert Xpress Multiplex Vaginal Panel test (“MVP test”) was performed. …”
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Compensation of Speckle Noise in 2D Images from Triangulation Laser Profile Sensors Using Local Column Median Vectors with an Application in a Quality Control System by Paweł Rotter, Dawid Knapik, Maciej Klemiato, Maciej Rosół, Grzegorz Putynkowski

“…The main function of triangulation-based laser profile sensors—also referred to as laser profilometers or profilers—is the three-dimensional scanning of moving objects using laser triangulation. …”
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