Assessment of test-retest reproducibility by [18F]Bavarostat for PET imaging of HDAC6 by Mika Naganawa, Ming-Qiang Zheng, Jean-Dominique Gallezot, Robin Bonomi, Jiwei Gu, Hong Gao, Swanee Jacutin-Porte, Nabeel B. Nabulsi, Michel Koole, Koen Van Laere, David Matuskey, Yiyun Huang, Richard E. Carson

“…Arterial blood sampling and metabolite analysis were performed to derive the input function. …”
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Assessment of the significance of factors associated with the development of long-term adverse cardiovascular events in type 2 diabetes mellitus by D. V. Grazhdankina, I. A. Bondar, A. A. Demin

“…In patients with T2D clinical and laboratory data were evaluated. A 6-minute walk test (6MWT) and echocardiography were performed. …”
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Longitudinal characterization of the muscle metabolome in dairy cows during the transition from lactation cessation to lactation resumption by H. Sadri, M.H. Ghaffari, H. Sauerwein, S. Schuchardt, J. Martín-Tereso, John Doelman, J.B. Daniel

“…The targeted metabolomics approach was conducted using the MxP Quant 500 kit (Biocrates Life Sciences AG) with liquid chromatography, flow injection, and electrospray ionization triple quadrupole mass spectrometry. Statistical analysis on the muscle metabolite data was performed using MetaboAnalyst 5.0, which allowed us to conduct various multivariate analyses such as principal component analysis (PCA), partial least squares discriminant analysis (PLS-DA), informative heat map generation, and hierarchical clustering. …”
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Reference genome provide insights into sex determination of silver aworana (Osteoglossum bicirrhosum) by Yi Liu, Chao Bian, Ka Yan Ma, Yexin Yang, Yuanyuan Wang, Chao Liu, Guochang Ouyang, Meng Xu, Jinhui Sun, Changwei Shao, Jiehu Chen, Qiong Shi, Xidong Mu

“…Transcriptome sequencing of gonads support our hypothesis that the regulation of foxl2 can be influenced by the spatial proximity of the female-specific fragment, thereby promoting ovarian function or inhibiting testicular function to stimulate gonadal differentiation. …”
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Hallmarks of glucocorticoid receptor condensates involvement in transcription regulation by Belén Benítez, Martin Stortz, María Cecilia De Rossi, Diego Martín Presman, Valeria Levi

“…As with all members of the steroid receptor family, GR forms condensates of unknown function. Here, we examine whether GR condensates are involved in transcription regulation using Airyscan super-resolution microscopy and nano-antibodies targeting initiation and elongating states of RNA polymerase II (Pol2). …”
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Drug repurposing reveals posaconazole as a CYP11A1 inhibitor enhancing anti-tumor immunity by Jhuma Pramanik, Sanu Korumadathil Shaji, Megan Zaman, Bethany Brown, Baojie Zhang, Yumi Yamashita-Kanemaru, Natalie Z.M. Homer, Hosni A.M. Hussein, Qiuchen Zhao, Klaus Okkenhaug, Rahul Roychoudhuri, Abhik Mukhopadhyay, Bidesh Mahata

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Identification of an immunological signature of long COVID syndrome by Gisella Guerrera, Manolo Sambucci, Eleonora Timperi, Mario Picozza, Andrea Misiti, Andrea Misiti, Roberta Placido, Silvia Corbisiero, Silvia D’Orso, Andrea Termine, Carlo Fabrizio, Francesca Gargano, Sharon Eleuteri, Luisa Marchioni, Veronica Bordoni, Luigi Coppola, Marco Iannetta, Chiara Agrati, Giovanna Borsellino, Luca Battistini

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An AI recognition method for children's clinical operative pain by skin potential (SP) signal by Mingxuan Huang, Cangcang Fu, Linbo Chui, Jiadong He, Xiaozhi Wang, Jikui Luo, Bin Wu, Yonggang Chen, Shaohua Hu, Jihua Zhu, Yubo Li

“…Conclusion: We developed a comprehensive SP recognition model, innovatively employing WT for SP signal analysis. This time-frequency analysis method, by preserving low-frequency features, is particularly suitable for SP signals. …”
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Understanding facilitators and barriers to adherence in home-based pulmonary rehabilitation for chronic obstructive pulmonary disease patients using the Health Belief Model: a qual... by Qiuxuan Zeng, Wenli Chen, Siyi Xu, Xu Yang, Dandan Xue, Yuhang Peng, Xiaohong Lin, Yingwen Yu, Huixin Huang, Ping Huang, Min Dong, Jiaying Li

“…Deductive thematic analysis approach was used to analyze the data.ResultsEighteen patients were recruited through purposive sampling. …”
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Older surgical patients’ preferences for follow-up care after hospital discharge: A multi-method qualitative study into their underlying needs by Aafke J de Groot, Marike E de Boer, Elizabeth M Wattel, Cees MPM Hertogh, Marja FIA Depla

“…Background: Almost 30 % of older patients suffer from functional decline during hospital stay which often makes follow-up care decisions necessary. …”
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Repurposed clindamycin suppresses pyroptosis in tumor-associated macrophages through Inhibition of caspase-1 by Adrian Weich, Johannes Berges, Cindy Flamann, Katrin Bitterer, Krishna Pal Singh, David Chambers, Christopher Lischer, Xin Lai, Olaf Wolkenhauer, Carola Berking, Gerhard Krönke, Shailendra Gupta, Heiko Bruns, Julio Vera, Research Group Macrophages

“…Methods In our work, we designed a novel computational pipeline that combines single-cell transcriptomics data, network analysis, multicriteria decision techniques, and pharmacophore-based docking simulations to select molecular targets and matching repurposable drugs for TAM immunomodulation. …”
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IFITM3 enhances immunosensitivity via MHC-I regulation and is associated with the efficacy of anti-PD-1/-L1 therapy in SCLC by Yanan Cui, Tianyu Qiu, Jiale Wang, Xinyu Liu, Libo Luo, Jizhong Yin, Xinxin Zhi, Wanying Wang, Gaohua Feng, Chunyan Wu, Zhikai Zhao, Hua Zhang, Fei Li, Fengying Wu, Shengxiang Ren

“…In vitro and in vivo functional studies were conducted to evaluate the role and mechanisms of IFITM3 in modulating tumor sensitivity to PD-1 inhibitors. …”
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Impact of exercise to treat postural orthostatic tachycardia syndrome: a systematic review by Melissa M. Cortez, Kayla Aikins, Amy C. Arnold, Jeffrey R. Boris, Todd E. Davenport, Todd E. Davenport, Katie Johnson, Katie Johnson, Hagar S. Kattaya, Hagar S. Kattaya, Laurence Kinsella, Mary M. McFarland, Ryan Pelo, Ryan Pelo, Clayton D. Powers, Kelsi Schiltz, Kelsi Schiltz, Lauren E. Stiles, Lauren E. Stiles, Lauren Ziaks, Tae Hwan Chung, Claudia Dal Molin

“…Exclusions: Non-English language papers and opinion-based/theoretical/non-empirical studies/case reports. Data extraction was based on Cochrane Handbook guidance and summarized according to Synthesis Without Meta-analysis (SWiM) guidelines; methodological quality and risk of bias was evaluated using the JBI Critical Appraisal tools. …”
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Temporal Trends in Stroke Management and Outcomes Between 2011 and 2020 in South Korea: Results From a Nationwide Multicenter Registry by Tai Hwan Park, Keun‐Sik Hong, Yong‐Jin Cho, Wi‐Sun Ryu, Dong‐Eog Kim, Man‐Seok Park, Kang‐Ho Choi, Joon‐Tae Kim, Jihoon Kang, Beom‐Joon Kim, Moon‐Ku Han, Jun Lee, Jae‐Kwan Cha, Dae‐Hyun Kim, Jae Guk Kim, Soo Joo Lee, Jee‐Hyun Kwon, Wook‐Joo Kim, Dong‐Ick Shin, Kyu Sun Yum, Sung Il Sohn, Jeong‐Ho Hong, Jay Chol Choi, Byung‐Chul Lee, Kyung‐Ho Yu, Mi‐Sun Oh, Jong‐Moo Park, Kyusik Kang, Kyungbok Lee, Sang‐Hwa Lee, Hae‐Bong Jeong, Kwang‐Yeol Park, Ji Sung Lee, Juneyoung Lee, Philip B. Gorelick, Hee‐Joon Bae

“…Background This study aims to evaluate temporal trends of advanced treatments and related clinical outcomes of ischemic stroke through a decade‐long trend analysis, using data from a comprehensive, national, multicenter registry. …”
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The Tuberculosis Sentinel Research Network (TB-SRN) of the International epidemiology Databases to Evaluate AIDS (IeDEA): protocol for a prospective cohort study in Africa, Southea... by Eugene Messou, Marcel Yotebieng, Lukas Fenner, Helen Byakwaga, Stephany N Duda, Kara Wools-Kaloustian, Marie Ballif, Timothy R Sterling, Denise Evans, Annette H Sohn, Carolyn Bolton-Moore, Armel Poda, Olivier Marcy, Neelima Navuluri, Nathalie De Castro, Leslie A Enane, Thida Chanyachukul, Nana Mbonze, LaQuita R McDade, Marina Cruvinel Figueiredo, Jeremy Ross, Lameck Diero, Robert Akpata, Natalia Zotova, Aimee Freeman, Marie Flore Pierre, Dhanushi Rupasinghe, Martine Tabala, Robin Huebner

“…Data regarding clinical and sociodemographic factors, mental health, health-related quality of life, pulmonary function, and laboratory and radiographic findings will be collected using standardised questionnaires and data collection tools, beginning from the initiation of TB treatment and through 12 months after the end of treatment. …”
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Band structure alignment in transfer-free MOCVD grown 2D-TMDC heterostructures revealed by ambient KPFM by M. Abdelbaky, Y. Beckmann, J. Klein, T. G. Fabunmi, N. Stracke, A. Grundmann, M. Heuken, H. Kalisch, A. Vescan, T. Kümmell, W. Mertin, G. Bacher

“…This resulted in a pristine interface and efficient interlayer coupling, as evidenced by a uniform work function of 4.6 eV for both stacking orders. Illumination experiments demonstrate the separation of photogenerated charge carriers across the heterointerface as visualized by distinct changes in the surface potential. …”
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Virtual reality navigation for the early detection of Alzheimer’s disease by Sayuri Shima, Reiko Ohdake, Yasuaki Mizutani, Harutsugu Tatebe, Riki Koike, Atsushi Kasai, Epifanio Bagarinao, Epifanio Bagarinao, Kazuya Kawabata, Kazuya Kawabata, Akihiro Ueda, Mizuki Ito, Junichi Hata, Shinsuke Ishigaki, Junichiro Yoshimoto, Hiroshi Toyama, Takahiko Tokuda, Akihiko Takashima, Hirohisa Watanabe, Hirohisa Watanabe

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Acmeological technology of forecasting individual professional-oriented trajectories of students’ personality development by E. F. Zeer, L. N. Stepanova

“…The method of structural and functional modelling of acmeological technology was applied. …”
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Exploring the active chemical compounds and pharmacological effects of Artemisia Argyi leaves through commonality, authenticity and aging by Boyu Chen, Jiaxin Liu, Xu Dai, Lufan Xu, Wenying Cui, Rouan Chen, Tian Lan, Yiider Tseng

“…Results: Our work highlights the potential key functional compounds of A. argyi leaves, including volatile substances, including 1,8-Cineole, β-Caryophyllene, p-Cymene and Caryophyllene oxide, as well as non-volatile compounds, including Eupatilin, Isochlorogenic acid C, Isochlorogenic acid A, and Vitexin. …”
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Multi-Objective Optimal Scheduling of Water Transmission and Distribution Channel Gate Groups Based on Machine Learning by Yiying Du, Chaoyue Zhang, Rong Wei, Li Cao, Tiantian Zhao, Wene Wang, Xiaotao Hu

“…This study develops a synergistic optimization method of multiple gates integrating hydrodynamic simulation and data-driven methods, with the goal of improving the accuracy of water distribution and regulation efficiency. …”
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