Clinical manifestations and results of reconstructive surgeries in patients with primary and secondary mitral insufficiency by O. F. Luchynets, V. V. Lazoryshynets, O. A. Krykunov

“…The study is based on the analysis of clinical data of 218 patients with mitral valve insufficiency who were treated in National M. …”
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Factors associated with health-related quality of life in hemodialysis patients in a Peruvian hospital: A cross-sectional study by Ariana Isabel Rojas Aliaga, Yoshua David Rojas Peña, Luis Jesus Arellan Bravo, Sarai Gloria Chavez Bustamante, Briam Cristiam Benito Condor

“…Likewise, there was a significant difference between the average values of the emotional role dimension (p = 0.038) of the SF-36 in the nutritional status levels and a significant difference between the average total scores of the SF-36 in the salary levels (p = 0.048). The multivariate analysis identified correlations between nutritional status and pain; educational level and vitality; nutritional status and physical role; economic income; educational level and social function; and nutritional status and emotional role. …”
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Thyroid Dysfunction After Intensity-Modulated Radiotherapy and PD⁃1 Inhibitor Treatment for Locally Advanced Nasopharyngeal Carcinoma by Shang K, He Q, Xu X, Luo X, Zhao C, Liu L, Li Z, Li Y, Jin F

“…Logistic regression analysis was used to screen independent risk factors for thyroid dysfunction.Results: As of data cutoff (May 31, 2024), the median follow-up time was 27.8 months (range: 25.6 to 32.0 months). …”
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Does peripheral neuroinflammation predict chronicity following whiplash injury? Protocol for a prospective cohort study by Mara Cercignani, Stephen Bremner, Alex Novak, Chetan Trivedy, Colette Ridehalgh, Joel Fundaun, Rupert Young, Jane Greening, Annina Schmid, Andrew Dilley

“…Participants will be invited to participate in a sub-study investigating the contribution of cutaneous small fibre pathology to WAD2.Methods and analysis 115 participants within 1 month following whiplash injury and 34 healthy control participants will be recruited and complete validated questionnaires for pain, function and psychological factors. …”
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ANO5 p.I616F variant drives florid cemento-osseous dysplasia by disrupting transmembrane domain structure by Lanlan Zhang, Wenxi Jin, Yunfa Qin, Yonghui Zhang, Yemei Qian, Jingyi Li, Yu Liu, Yan’an Shi, Rongju Xie, Weihong Wang

“…The mutation likely disrupts the α-helical structure of ANO5 protein, impairing its catalytic function and potentially dysregulating bone remodeling processes in FCOD pathogenesis.…”
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Construction and validation of a reliable disulfidptosis-related lncRNAs signature of the subtype, prognostic, and immune landscape in bladder cancer by Xiaoping Leng, Han Chen, Gang Chen

“…Cox and LASSO regression analysis were used to identify DRLs. Kaplan–Meier survival analysis, ROC curve, and nomograms were constructed to assess and forecast survival events. …”
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Biological activity and chemical characteristics studies of new oligomannose produced by Erwinia gerundensis by Shimaa K. Ali, F.M Mohamed, Ahmed H. El-Ghorab, Eman A. Hamed, Moustafa A. Aboel-Ainin, Mohamed A. Abdelgawad, Khaled El‐Adl, Hussein S. Mohamed

“…To assess the interaction between the exopolysaccharide and the active sites of Bacillus cereus and E. coli, molecular docking experiments were conducted using five monosaccharides: d-xylose, d-glucose, l-arabinose, ribose, and d-mannose. The data obtained from the molecular docking analysis strongly correlates with the findings from biological studies.Furthermore, these highly active compounds exhibit a favorable proposed ADMET profile. …”
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Thermogravimetric studies of a nasal preparation with an interleukin-1β (IL-1Ra) antagonist by B. S. Burlaka

“…Interleukin-1 receptor antagonist (IL-1Ra) is an active pharmaceutical ingredient obtained by the method of gene transformation of Escherichia coli, provides a neuroprotective effect, namely – inhibition of oxidative modification of proteins, normalization of functional activity of mitochondrial energy, mitochondrial energy. …”
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The Dysregulation of Tuning Receptors and Transcription Factors in the Antennae of <i>Orco</i> and <i>Ir8a</i> Mutants in <i>Aedes aegypti</i> Suggests a Chemoreceptor Regulatory M... by Matthew M. Cooke, Michael S. Chembars, Ronald Jason Pitts

“…In <i>Drosophila melanogaster</i>, disruptions of <i>Orco</i> or <i>Ir8a</i> impair receptor function, tuning receptor expression, and membrane localization, leading to general anosmia. …”
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The physiological neocerebellar extinction syndrome likely exists for human handedness but not footedness – a study on healthy young adults by Martin Musálek, Chipo Malambo, Petr Kubový

“…This study explored the relationship between physiological neocerebellar extinction syndrome and hand/ft dominance in left and right-side dominant individuals. Data were collected from 80 university participants (40 left-side dominant, 40 right-side dominant, mean age = 24.7 ± 0.92 years) during controlled limb falls using 3D kinematic analysis. …”
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Study of the corrective ability of sync codes for the matched processing decoder by A. V. Sadchenko, O. A. Kushnirenko, A. G. Yurkevych, V. S. Sevastianov

“…Increase of the operation reliability of the frame synchronization schemes of communication systems affected by interferences might be achieved by using sync sequences optimal according to the minimax criterion and having the best ratio of the maximum side-lobe level to the main peak of the non-periodic autocorrelation function. Obviously, the longer the minimax sequence, the higher its correction ability. …”
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The Inhibitory Effects of Alpha 1 Antitrypsin on Endosomal TLR Signaling Pathways by Ahmed S. Elshikha, Georges Abboud, Rigena Avdiaj, Laurence Morel, Sihong Song

“…Human AAT also lowered the expressions of interferon signature genes. Western blot analysis showed that hAAT reduced the expression of the active form (cleaved) of TLR9 in DCs, indicating a novel mechanism of hAAT function in the immune system. …”
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Dynamics of Ecosystem Services Driven by Land Use Change Under Natural and Anthropogenic Driving Trajectories in the Kaduna River Basin, Nigeria by Liehui Zhi, Usman Abdullahi, Qingyue Zhang, Xin Wang, Xiaowen Li

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Organ donation and transplantation in the Russian Federation in 2016 9th report of the National Registry by S. V. Gautier, S. M. Khomyakov

“…Questioning of the heads of all the centers of transplantation is carried out. The comparative analysis of the obtained data in dynamics of the years, between certain regions of the Russian Federation and transplantation centers is done. …”
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Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow by Alejandro Gomez Toledo, Sounak Chowdhury, Elisabeth Hjortswang, James T. Sorrentino, Nathan E. Lewis, Anna Bläckberg, Simon Ekström, Sven Kjellström, Arman Izadi, Berit Olofsson, Pontus Nordenfelt, Lars Malmström, Magnus Rasmussen, Johan Malmström

“…A selected subset of the identified antigens is then expressed recombinantly to isolate antigen-specific IgG, followed by characterization of the structural and functional properties of these antibodies. We focused on Group A streptococcus (GAS), a major human pathogen lacking an approved vaccine. …”
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A DSL-Driven Solution and Code Generation for Accelerated Tourism Decision Support System Development by Adnane Souha, Charaf Ouaddi, Lamya Benaddi, Hamza Abdelmalek, El Mahi Bouziane, Abdeslam Jakimi

“…Decision Support Systems (DSS) play a crucial role in commerce and tourism by assisting decision-making through data analysis, modeling, and visualization. However, their development is often complex, costly, and requires expertise in both software engineering and Artificial Intelligence, making them inaccessible to many organizations. …”
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Investigation of structural features of asphaltenes used for carbon materials synthesis by arc plasma treatment by Andrey Grinko, Evgenia Leushina, Yuliya Petrova, Pavel Povalyaev, Alexander Pak, Arina Goncharova, Vasily Kaichev, Valentina Egorova, Kirill Cherednichenko, Dmitry Zelentsov, Tatiana Cheshkova

“…This study presents analysis of asphaltenes isolated from two crude oils: naphthenic-aromatic biodegraded oil and paraffin-naphthenic oil, which have been used as precursors for carbon materials synthesis. …”
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From life cycle assessment to grass‐based agriculture: A review and application by Yutong Li, Shu Jin, Xiaoping Xin, Yi An, Lili Huo, Changliang Shao, Lulu Wang, Xiaoyu Zhu

“…The study emphasizes (1) the selection of LCA methods should align with specific research objectives, focusing not only on environmental impacts but also comprehensively considering social impacts and economic benefits; (2) it provides a comprehensive overview with an expanded scope selection beyond the “from cradle to farm gate” boundary and uses product value as the functional unit to facilitate assessments across various crop types, particularly focusing on inventory analysis and impact assessment; (3) challenges including model integration, impact sensitivity, and data uncertainty persist in the LCA of grass‐based agriculture; and (4) multidimensional frameworks effectively integrate both quantitative and qualitative factors into grass‐based agriculture, further enhancing the understanding of LCA results and supporting decision‐making. …”
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Changes in subarctic Pacific phytoplankton communities over the last two decades by Marta Konik, Marta Konik, Marta Konik, Brian P. V. Hunt, M. Angelica Peña, Toru Hirawake, Christian Marchese, Christian Marchese, Christian Marchese, Perumthuruthil Suseelan Vishnu, Perumthuruthil Suseelan Vishnu, Astrid Bracher, Astrid Bracher, Hongyan Xi, Maycira Costa

“…A time series of satellite phytoplankton phenology metrics and phytoplankton functional groups between 2002 and 2022 were analyzed. …”
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Interlayer engineering of lattice dynamics and elastic constants of 2D layered nanomaterials under pressure by Guoshuai Du, Lili Zhao, Shuchang Li, Jing Huang, Susu Fang, Wuxiao Han, Jiayin Li, Yubing Du, Jiaxin Ming, Tiansong Zhang, Jun Zhang, Jun Kang, Xiaoyan Li, Weigao Xu, Yabin Chen

“…Intriguingly, it is found that the layer-dependent dω/dP of shear (S N,1) and breathing (LB N,N-1) modes display the opposite trends, quantitatively consistent with MCM analysis, our molecular dynamics simulations and density functional theory calculations. …”
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