Gene polymorphisms of miR-323b and miR-1343 that regulate kininogen L are associated with schizophrenia susceptibility: A preliminary population‑based study by Xiaoyu Liu, Mengdi Jin, Mingjia Yang, Lijuan Yan, Weijiao Zhao, Lizhuo Liu, Hongmin Wang, Yongzhuo Ding, Yanyan Sun, Yanchi Zhang, Qiong Yu

“… miR-SNP is a type of functional single nucleotide polymorphism (SNP) that affects the regulatory functions of miRNA genes, miRNA binding sites, or components of miRNA biogenesis. …”
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Sex specific gut-microbiota signatures of resilient and comorbid gut-brain phenotypes induced by early life stress by Lars Wilmes, Valentina Caputi, Thomaz F.S. Bastiaanssen, James M. Collins, Fiona Crispie, Paul D. Cotter, Timothy G. Dinan, John F. Cryan, Gerard Clarke, Siobhain M. O'Mahony

“…Behavioural data were processed in a two-step cluster analysis to identify groupings within the dataset. …”
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Presenting the Model of Effective Factors on Smart Governance in the Country by Ghaem Gheiravani, Mohammad Montazeri, Shams Sadat Zahedi

“…In the qualitative part, the fuzzy Delphi method was used, and the data from the interviews were coded and analyzed in the three main stages of open coding; axial coding; and selective coding, and SmartPLS 3 software was used in the quantitative part of factor analysis, and SPSS 22 software was used for analysis. …”
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Spatiotemporal Variation and Driving Mechanisms of Carbon Budgets in Territorial Space for Typical Lake-Intensive Regions in China: A Case Study of the Dongting Lake Region by Suwen Xiong, Zhenni Xu, Fan Yang, Chuntian Gu

“…Using exploratory spatiotemporal data analysis, this study identifies grid-scale variation patterns in carbon budgets. …”
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Digitalisation of Professional Education: Prospects and Invisible Barriers by L. M. Andryukhina, N. O. Sadovnikova, S. N. Utkina, A. M. Mirzaahmedov

“…The methods of questionnaire-based survey, sociological analysis, statistical data-processing tools and Google Forms tools were used.Results and scientific novelty. …”
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Exploration of key genes and pathways in response to submergence stress in red clover (Trifolium pratense L.) by WGCNA by Panpan Shang, Lei Bi, Wenwen Li, Xiaoli Zhou, Yanlong Feng, Jiahai Wu, Bing Zeng

“…Functional annotation of the DEGs in the four key modules was obtained. …”
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High expression of SOX10 is correlated with poor prognosis and immune infiltrates in skin cutaneous melanoma by Xu Sun, Yi-ming Cheng, Meng-wei Sun, Xu-dong Zhang, Xiao-yu Yu, Hai-bo Wang, Yi-fei Wang, Ning Li

“…Moreover, functional enrichment analysis of SOX10-related DEGs was performed by GO/KEGG, GSEA. …”
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Gray matter abnormalities and memory impairment in left mesial temporal lobe epilepsy by Agnieszka Olejnik, Aleksandra Bala, Weronika Rejner, Antonina Gottman-Narożna, Andrzej Rysz, Maja Kopytek-Beuzen, Patrycja Naumczyk, Przemysław Kunert

“…Most previous studies have focused on assessing declarative memory directly related to hippocampal functions, but emerging data suggest a decline in the efficiency of other types of memory as well. …”
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Nonresponse Bias on Inpatient Rehabilitation Hospitals’ Experience of Care Quality Measure Scores by Allen Walter Heinemann, PhD, Anne Deutsch, RN, PhD, CRRN, Dave Brewington, PhD, Linda Foster, PT, Karon Frances Cook, PhD, Ana Miskovic, BA, David Cella, PhD

“…There were no differences in the proportions of patients answering favorably on the IRF Survey (all respondents) compared with the Research Survey, except for physician communication and discharge information. Mutual information analysis revealed agreement between the scores produced by the 2 data sources. …”
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Randomised clinical trial research within Aboriginal and Torres Strait Islander primary health services: a qualitative study by Tim Usherwood, Jennifer Reath, Amanda Jane Leach, Hasantha Gunasekera, Deborah Askew, Penelope Abbott, Chelsea Watego, Wendy CY Hu, Letitia Campbell, Claudette Tyson, Robyn Walsh, Sylvia Hussey, Kerrie Doyle, Jessica Armstrong-Kearns

“…The data comprised agreed records of research meetings, and semistructured interviews with clinical trial stakeholders. …”
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Cell-intrinsic PD-L1 signaling drives immunosuppression by myeloid-derived suppressor cells through IL-6/Jak/Stat3 in PD-L1-high lung cancer by Bhumsuk Keam, Se-Hoon Lee, Yingying Li, Yoon Kyung Jeon, Hye Young Kim, Sehui Kim, Hyein Jeong, Soo Hyun Lee, Jaemoon Koh, Jeemin Yim, Seung Geun Song, Hanbyeol Kim, Yeon Kyu Chung, Hongsoon Kim, Chul-Hwan Lee, Doo Hyun Chung

“…To address the mechanism of ICI resistance in PD-L1-positive NSCLC, we investigated the role of tumor-cell-intrinsic function of PD-L1 in interleukin (IL)-6-mediated immunosuppression.Methods Cohorts of NSCLC patients treated with ICI and public datasets were analyzed. …”
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Metabolomics and proteomics insights into hepatic responses of weaned piglets to dietary Spirulina inclusion and lysozyme supplementation by Cátia Falcão Martins, Manolis Matzapetakis, David M. Ribeiro, Josipa Kuleš, Anita Horvatić, Nicholas Guillemin, Peter David Eckersall, João P. B. Freire, André M. Almeida, José A. M. Prates

“…At the end of the trial, animals were sacrificed and liver tissue was collected. Metabolomics analysis (n = 10) was performed using NMR data analysed with PCA and PLS-DA. …”
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Supplemental oxygen for pulmonary embolism (SO-PE): study protocol for a mechanistic, randomised, blinded, cross-over study by Nour Al Jalbout, Hamid Shokoohi, Christopher Kabrhel, David M Dudzinski, Mads Dam Lyhne, Andrew S Liteplo, Oana Alina Zeleznik, Asger Andersen, Onyinyechi Franca Eke, Christina C Morone, Calvin K Huang, Thomas F Heyne, Mannudeep K Kalra

“…Oxygen is a known pulmonary vasodilator, and in preclinical animal models of PE, supplemental oxygen reduces PA pressures and improves RV function. However, the mechanisms driving these interactions, especially in humans, remain poorly understood. …”
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Analyzing Worn-Out Texture Regeneration from Urban Branding Perspective Using Structural Equation Modeling (SEM) (Case Study: Worn-Out Texture of Shahr-e-Kord) by Dvood Mahdavi, Ali Mohammadi Gojani, Waliullah Nazari

“…Structural Equation Modeling (SEM) in PLS software was employed for data analysis. The results indicated that physical and spatial interventions (path coefficient of 0.508) had the most significant impact on the effective regeneration of Shahr-e-Kord worn-out fabric followed by marketing and place promotion components (coefficient of 0.355). …”
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Comparative efficacy of interventional therapy with or without targeted immunotherapy in Child-Pugh B hepatocellular carcinoma patients: a single-center, retrospective study by Xu-Wei Guo, Man Zhao, Xiao-Ling Duan, Guang-Jie Han, Jin-Feng Wang, Jian-Fei Shi, Xin Han, Fei Yin, Guang Yang

“…BackgroundCurrent large clinical trials mainly focus on Child-Pugh A (CP-A) stage hepatocellular carcinoma (HCC) patients, with limited data on CP-B patients especially those classified as B8-9, whose treatment needs remain inadequately addressed. …”
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Identification of a Rare Mutation in the SRD5A2 Gene in an Iranian Family with Sex Development Disorder by Atiyeh Ataei, Peyman Eshraghi, Atiyeh Eslahi, Zeinab Khazaei, Masoome Alerasool, Sara Jamali, Faranak Ghadamyari, Majid Mojarrad

“…According to WES result and Sanger sequencing a homozygote loss of function mutation (c.16C>T; p.Gln6Ter) in SRD5A2 has been detected. …”
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Effects of a Novel COL4A3 Homozygous/Heterozygous Splicing Mutation on the Mild Phenotype in a Family With Autosomal Recessive Alport Syndrome and a Literature Review by Dan Chen, Li Zhang, Jing Rao, Yan Zhou, Lujun Dai, Songsong Huang, Chunxia Yang, Qiuhan Bian, Tao Zhang, Xiaoyan Yang

“…Next, we used bioinformatics, renal biopsy pathology, and an in vitro minigene experiment. Complementary analysis of clinical data was carried out, and we explored the expression and function of the variants to verify their pathogenicity. …”
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New insights on poly(cis-1,4-isoprene) rubber degradation through enzymatic kinetics and process improvement by Camila Guajardo-Flores, Camila Guajardo-Flores, Josefa Rojas, Yvan Baldera-Moreno, Francisco Adasme-Carreño, Francisco Adasme-Carreño, Daisuke Kasai, Rodrigo Andler

“…Furthermore, Fukui function analysis suggested that the aldehyde terminal groups of the oligoisoprenoids may be less susceptible to enzymatic degradation, which would explain the mass distribution of the degradation products.…”
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Prevalence and clinical significance of anti-neutrophil cytoplasmic antibodies in rheumatoid arthritis-associated interstitial lung disease by Zhe Huang, Tingting Wu, Rongdan Lu, Haijun Zhou, Yun Zhang, Li Huang, Yongxiong Gan, Hequn He

“…Compared with ANCA-negative RA-ILD patients, a greater proportion of ANCA-positive RA-ILD patients had respiratory symptoms, serum autoantibody (ANA) positivity, poorer baseline pulmonary function, and acute exacerbations of ILD (AE-ILD). …”
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Breast milk: its components and special effects on newborns and infants by T. Voroncova, T. Konyk, M. Trokhymenko, Y. Mudryk

“…Preference was given to systematic reviews, clinical trials, and analytical articles published in English. The analysis covered current, verified data on the composition of breast milk and its impact on the microbiota and infant health. …”
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