IGF1R Promotes Th17/Treg Cell Development in Experimental Autoimmune Prostatitis by Guan Y, Yue S, Chen Y, Cheng A, Li H, Yang F, Liu Y, Liang C, Meng J

“…Statistical significance was defined as P < 0.05, and all tests were conducted as two-tailed. Data analysis was performed using R software (version 4.2.2).Results: We successful established the EAP model and discovered that the expression of IGF1R, content of IGF1-related ligands, was highest in prostate tissue and CD4+ T cell subset. …”
Get full text

Study on the correlation of nutritional status with clinical and pathological characteristics of patients with IgA nephropathy by Du Yan-bin, Du Yan-ling, Li Huan, Yuan Zu-jun

“…ObjectiveTo explore the correlation of serum total protein， albumin， and prognostic nutritional index （PNI） with the clinical and pathological characteristics of IgA nephropathy （IgAN）， and to evaluate the impact of these nutritional indicators on the severity of IgAN.MethodsA total of 218 IgAN patients who were treated at Nephrology Department of Nanchong Central Hospital from January 1， 2019， to April 1， 2024 were included in this study. Baseline data， blood biochemistry results， nutritional and renal function indicators were collected from the patients. …”
Get full text

Molecular characterization and expression profiles of cytochrome P450 reductase gene in Sogatella furcifera (Hemiptera: Delphacidae) by YU Hang, LIU Su, ZHU Qingzi, ZHOU Wenwu, LIANG Qingmei, SHI Xiaoxiao, ZHU Zijie, ZHU Zengrong

“…These findings provide foundation for further research on the physiological function of SfCPR.…”
Get full text

Improvement of myocardial fibrosis injury by Shengmai injection in ischemia-induced heart failure in a rat model by Yurong Ding, Junying Wei, Enhui Ji, Menglan Wang, Yue Wu, Mengli Chang, Yi Zhang, Jing Xu

“…The protein-protein interaction relationship was constructed, and biological function was applied to evaluate the advantage effect of SMI in the progression of MI-induced HF. …”
Get full text

Eye health and quality of life: an umbrella review protocol by Nathan Congdon, Hannah Kuper, Matthew J Burton, Jacqueline Ramke, Jennifer Evans, Fatimah Chamseddine, Joshua R Ehrlich, Bonnielin K Swenor, Lama Assi, Lori Rosman, Perla Ibrahim, Hadi Sabbagh

“…Quality of life, whether generic, vision-specific or disease-specific, is an important measure of the impact of eye health on people’s daily activities, well-being and visual function, and is increasingly used to evaluate the impact of ophthalmic interventions and new devices. …”
Get full text

Acute Cardiovascular Effects of Simultaneous Energy Drink and Alcohol Consumption in Young Adults: A Review of Case Reports by Victor Azarm, Jan-Philipp Link, Guido Mandilaras, Pengzhu Li, Robert Dalla-Pozza, André Jakob, Nikolaus Alexander Haas, Felix Sebastian Oberhoffer, Meike Schrader

“…The three parts of the cardiovascular system affected were heart rhythm (42%), myocardial function (33%), and coronary arteries (25%). In 3 cases the outcome was fatal. …”
Get full text

The concept of “ambulatory” and “non-ambulatory” in patients with Duchenne muscular dystrophy: definitions and criteria by T. A. Gremyakova, S. V. Artemyeva, N. D. Vashakmadze, I. P. Vitkovskaya, V. I. Guzeva, O. V. Guzeva, L. M. Kuzenkova, S. V. Mikhailova, L. P. Nazarenko, T. M. Pervunina, N. L. Pechatnikova, T. V. Podkletnova, G. E. Sakbaeva, A. A. Stepanov, V. M. Suslov, O. I. Gremyakova, N. I. Shakhovskaya, S. S. Nikitin

“…In patients, muscle damage and atrophy progresses, the ability to move independently decreases as well as respiratory and cardiac functions. At various stages of the disease, different methods of care and treatment of patients with DMD are used. …”
Get full text

Comparative response mechanisms of two cultivars of Musa paradisiaca L. to Fusarium oxysporum f.sp. cubense infection by Yajie Duan, Yajie Duan, Zhiwei Jia, Zhiwei Lu, Huigang Hu, Rulin Zhan

“…Through the perspective of transcriptome data, we focused on genes associated with lignin and cell wall development for Q-PCR validation. …”
Get full text

Genome-Wide Scan for Copy Number Variations in Chinese Merino Sheep Based on Ovine High-Density 600K SNP Arrays by Yuezhen Tian, Jing An, Xinning Zhang, Jiang Di, Junmin He, Ayinuer Yasen, Yanpin Ma, Gaohaer Sailikehan, Xixia Huang, Kechuan Tian

“…To generate a comprehensive CNVR map of the ovine genome, we conducted genome-wide CNV detection using genotyping data from 285 fine wool sheep. This analysis revealed 656 CNVRs, including 628 on autosomes and 28 on the X chromosome, covering a total of 43.9 Mbs of the sheep genome. …”
Get full text

Identification of the putative regulatory regions and candidate genes associated with backfat thickness and intramuscular fat content traits in Xiang pigs by Xia Chen, Yundi Zheng, Fengbin Hu, Xiaoli Liu, Wei Wang, Fenfang Qi, Xi Niu, Shihui Huang, Jiafu Wang, Xueqin Ran

“…These findings enhance our understanding of the genetic mechanisms underlying fat deposition in Xiang pigs and provide a theoretical framework for future functional studies and genomic selection.…”
Get full text

Sarcopenia diagnosis using skeleton-based gait sequence and foot-pressure image datasets by Muhammad Tahir Naseem, Na-Hyun Kim, Haneol Seo, JaeMok Lee, Chul-Min Chung, Sunghoon Shin, Chan-Su Lee

“…IntroductionSarcopenia is a common age-related disease, defined as a decrease in muscle strength and function owing to reduced skeletal muscle. One way to diagnose sarcopenia is through gait analysis and foot-pressure imaging.Motivation and research gapWe collected our own multimodal dataset from 100 subjects, consisting of both foot-pressure and skeleton data with real patients, which provides a unique resource for future studies aimed at more comprehensive analyses. …”
Get full text

Study on the Response of Net Primary Productivity to Vegetation Phenology and Its Influencing Factors in Karst Ecologically Fragile Regions by Jiale Wang, Zhongfa Zhou, Meng Zhu, Jiaxue Wan, Xiaopiao Wu, Rongping Liu, Jiajia Zheng

“…Net primary productivity (NPP) is a crucial indicator of ecosystem function and sustainability. Quantifying the response of NPP to phenological dynamics is essential for understanding the impact of climate change on ecosystem processes. …”
Get full text

Biomarker identification for rheumatoid arthritis with inadequate response to DMARD and TNF therapies using multidimensional analyses by Leyuan Li, Hui Guo, Weijin Zhang, Xi Xiang, Jun Chi, Mengmeng Zhang, Jiali Chen, Zhimin Wang, Liping Dai

“…The CIBERSORT algorithm and single sample Gene Set Enrichment Analysis (ssGSEA) were employed for immune infiltration analysis and functional enrichment analysis, respectively. …”
Get full text

Detecting Conversation Topics in Recruitment Calls of African American Participants to the All of Us Research Program Using Machine Learning: Model Development and Validation Study by Priscilla Pemu, Michael Prude, Atuarra McCaslin, Elizabeth Ojemakinde, Christopher Awad, Kelechi Igwe, Anny Rodriguez, Jasmine Foriest, Muhammed Idris

“…MethodsOur study design was an observational, retrospective approach using machine learning for content analysis. Specifically, we used structural topic modeling to identify and compare latent topics of conversation in recruitment calls by Morehouse School of Medicine RAs between February 2021 and April 2022 by estimating expected topic proportions in the corpus as a function of enrollment and participation in AoURP. …”
Get full text

Lower expression of miR-218 in human breast cancer is associated with lymph node metastases, higher grades, and poorer prognosis by Fereshteh Ahmadinejad, Seyed Javad Mowla, Mohammad-Amin Honardoost, Mostafa Gholami Arjenaki, Mohammad Moazeni-Bistgani, Soleyman Kheiri, Hossein Teimori

“…The correlation of both miR-218 and BMI1 gene expression with overall survival of breast cancer patients was also examined recruiting OncoLNC data portal. Finally, to better understand biological function of miR-218 in breast cancer, we performed in silico Gene Ontology and signaling pathway enrichment analysis on miR-218 targetome. …”
Get full text

Dietary magnesium intake affects the association between dietary vitamin A and depression: a cross-sectional study by Canqun Yan, Conghui Gao, Kebin Zhan, Cheng Li

“…The final analysis included 25,277 adults aged ≥20 years (Female: 12,581, Male:12,696), excluding pregnant women, individuals under 20, and those with incomplete data. …”
Get full text

Dietary Habits as Acne Trigger by Esma Karahmet Farhat, Ines Banjari, Tamara Jovović Sadiković

“…A properly balanced diet provides nutrients that the human body needs to function and reduces the appearance of acne. Significant differences between adults and adolescents have been observed in the daily intake of PUFAs and calcium, and nearly significant differences have been reported for vitamin B intake. …”
Get full text

Investigating the effect of online narrative therapy on the genital self-image and sexual satisfaction of infertile women: a randomized controlled trial by Fatemeh Shahriari, Armin Firoozi, Marzieh Azizi, Narges Moslemyzadeh, Abolfazl Hossein Nataj, Soghra Khani

“…SPSS version 22 software and statistical tests such as Mann–Whitney U, Friedman, Bonferroni test, and repeated measures ANOVA were used for data analysis. Results The Mann–Whitney U test showed that the mean score of the genital self-image in infertile women in the intervention and control groups showed no significant differences before the intervention (p = 0.312). …”
Get full text

Niveles de resiliencia en base a modalidad, nivel y lesiones deportivas (Levels of resilience based on sport discipline, competitive level and sport injuries) by Manuel Castro Sánchez, Ramón Chacón Cuberos, Felix Zurita Ortega, Tamara Espejo Garcés

“…The aim of this study is to analyze the relationships between resilience and sports injuries as a function of the competitive level. For this research, data from 43 athletes practicing football, handball and winter sports (ski and snowboard) were analyzed, using the CD-RISC questionnaire and a checklist of injuries and competitive level. …”
Get full text

Mode of delivery and outcomes among inborn extremely preterm singletons: A cohort study by Colm P. Travers, Dhuly Chowdhury, Abhik Das, Namasivayam Ambalavanan, Myriam Peralta‐Carcelen, Nancy Newman, Shirley Cosby, Myra Wyckoff, Alan Tita, Waldemar A. Carlo, For the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network

“…Death or severe neurodevelopmental impairment (Bayley Scales of Infant Development‐3rd edition cognitive composite score<70, cerebral palsy (Gross Motor Function Classification Scale >3), bilateral blindness, or bilateral hearing loss) at 18–26 month follow‐up were compared by mode of delivery (cesarean, vaginal including vertex or breech) using propensity score analysis to adjust for baseline characteristics. …”
Get full text