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15261
Mitochondrial genome of Lonicera macranthoides: features, RNA editing, and insights into male sterility
Published 2025-01-01“…RNA editing events were identified by integrating the mitogenome data with RNA sequencing data from leaf, stem, and flower tissues. …”
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15262
The UFMylation pathway is impaired in Alzheimer’s disease
Published 2024-12-01“…We further studied associations of the UFMylation cascade with cellular stress pathways using Spearman correlations with bulk RNAseq expression data and functionally validated these interactions using gene-edited neurons that were generated by CRISPR-Cas9. …”
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15263
Enhancer profiling uncovers Jmjd1c as an essential suppressor in neuropathic pain by targeting Socs3
Published 2025-09-01“…We first established a NP model in rats, and subsequently performed H3K27ac ChIP-Seq and RNA-Seq on their spinal cord tissues to analyze the active enhancers. By integrated analysis of ChIP-seq data and RNA-seq data, we clarified a series of SE-associated genes involved in NP progression. qPCR and double immunofluorescence staining results suggested that Jmjd1c mRNA and protein levels were significantly down-regulated in the NP model. …”
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15264
Clinical Predictive Factors for Reproductive Organ Involvement in Females with Muscle Invasive Bladder Cancer: A Retrospective Review of Radical Cystectomy Cases from Two Tertiary...
Published 2025-08-01“…Background: The preservation of reproductive organs in females with muscle-invasive bladder cancer (MIBC) might improve reproductive and sexual function. This study aimed to identify potential clinical risk factors for reproductive organ involvement (ROI) using preoperative data from transurethral resection of tumor (TURT) reports and imaging findings. …”
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15265
STIL Overexpression Is Associated with Chromosomal Numerical Abnormalities in Non-Small-Cell Lung Carcinoma Through Centrosome Amplification
Published 2024-12-01“…To elucidate the functional role of STIL, an inducible STIL-overexpressing H1299 NSCLC cell line was generated. …”
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15266
Order–Disorder-Type Transitions Through a Multifractal Procedure in Cu-Zn-Al Alloys—Experimental and Theoretical Design
Published 2025-05-01“…Then, through self-modulations of the thermal field, the Cu-Zn-Al alloy will self-structure in channel-type or cellular-type thermal patterns, which can be linked to obtained experimental data. Consequently, since the thermal conductivity becomes a function of the observation scale, and heat transfer is modified to reflect the multifractal, non-differentiable paths in the material, it leads to anomalous diffusion and complex thermal behaviors.…”
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15267
Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning
Published 2025-01-01“…Twelve protein structures were predicted using AlphaFold 3, revealing potential functional conformations. We observed a strong correlation between hub RMITRGs and immune cells, and PPI network analysis revealed key interactions. …”
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15268
Modeling growth curve parameters in Peruvian llamas using a Bayesian approach
Published 2025-06-01“…The MCMC method using the Metropolis-Hastings algorithm with noninformative prior distributions was applied in the Bayesian approach. All non-linear functions closely fitted actual body weight measurements, while the Brody function provided the best fit in both frequentist and Bayesian approaches in describing the growth data of llamas. …”
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15269
SCUP-HPC: System for Constructing and Utilizing Provenance on High-Performance Computing Systems
Published 2025-01-01“…In computing systems, provenance typically describes a suite of data relationships between simulation and analysis results, programs that generate results, and the input data fed to the programs. …”
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15270
SOME ASPECTS OF THE EATIOLOGY OF PARODONTUS DISEASES. (LITERATURE REVIEW)
Published 2018-06-01“…The article presents the data obtained in the course of studying the literature on the role of disorders in the functioning of individual organs (gastrointestinal tract, liver, lungs, heart, and urinary system) in the development of chronic periodontal diseases. …”
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15271
The crucial role of neutrophil extracellular traps and IL-17 signaling in indomethacin-induced gastric injury in mice
Published 2025-04-01“…GO functional annotations and KEGG pathway enrichment analysis were conducted on significant differential proteins. …”
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15272
Patient Reported Outcomes from an Open Label, Multi-Center, Retrospective Study of a Biodegradable Graft for Soft Tissue Reconstruction in Patients Suffering from Chronic Lateral A...
Published 2024-12-01“…These results represent an interim data analysis of an ongoing clinical study. A total of 47 patients diagnosed with chronic lateral ankle instability that had failed conservative therapy, and required surgical intervention to repair the lateral ligament complex were enrolled across two different research centers. …”
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15273
Evaluating the Effectiveness of an Intelligent mHealth Intervention for Child Unintentional Injury Prevention: Protocol for a Cluster Randomized Controlled Trial
Published 2025-07-01“…Secondary outcomes include children’s injury risk level and caregiver supervision behaviors assessed using a standard questionnaire. Data analysis will be conducted using generalized linear mixed models with a Poisson link function and generalized estimating equations to assess the effectiveness of the iCURE intervention, following intention-to-treat principles. …”
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15274
Variabilidade interanual da profundidade óptica da atmosfera sobre Maceió, AL Interannual variability of the optical depth of the atmosphere on Maceió, Alagoas
Published 2007-10-01“…A study of the variability of the optical depth of the atmosphere over Maceió, in the State of Alagoas, using incoming solar radiation in the top of the atmosphere and surface, was carried through long wave radiation (ROL), cloud covering, precipitable water and precipitation using the NCAR/NCEP re-analysis data set. The annual cycle of the optical depth obtained with these data, was compared through observed global radiation from the UFAL meteorology department's data set for the period from 1997 to 1999. …”
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15275
The proximal hamstring avulsion clinical trial (PHACT)—a randomised controlled non-inferiority trial of operative versus non-operative treatment of proximal hamstrings avulsions: s...
Published 2019-09-01“…Data analysis will be blinded and intention-to-treat analysis will be preformed.Ethics and dissemination Ethical approval has been granted by the Ethical Committee of Uppsala University (DNR: 2017–170) and by the Norwegian ethical board (REC: 2017/1911). …”
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15276
Evaluation of wastewater percent positive for assessing epidemic trends - A case study of COVID-19 in Shangrao, China
Published 2025-03-01“…Wastewater samples were obtained through grabbing and laboratory testing was completed within 24 h. The data were then normalized using Z-score normalization and analyzed for lag time and correlation using the xcorr function and Spearman correlation coefficient. …”
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15277
PCBP2 promotes immune evasion via cGAS-STING pathway in biochemical recurrence of prostate cancer
Published 2025-03-01“…The scRNA-seq data analysis revealed higher immune evasion scores in tumor cells compared to normal cells. …”
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15278
Construction of mitochondrial signature (MS) for the prognosis of ovarian cancer
Published 2025-07-01“…Functional enrichment analysis was performed on this prognostic gene set. …”
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15279
OpenPheno: an open-access, user-friendly, and smartphone-based software platform for instant plant phenotyping
Published 2025-06-01“…Conclusions By leveraging cloud computing and a widely accessible interface, OpenPheno democratizes plant phenotyping, making advanced tools available to a broader audience, including plant scientists, breeders, and even amateurs. It can function as a role in AI-driven breeding by providing the necessary data for genotype-phenotype analysis, thereby accelerating breeding programs. …”
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15280
Prognostic significance of acute exacerbations and usual interstitial pneumonia in fibrotic interstitial lung disease
Published 2025-07-01“…Baseline clinical information, pulmonary function tests, and chest images were collected and analysed. …”
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