Protocol for a prospective cohort study to determine the multimodal biomarkers of delirium and new dementia after acute illness in older adults: ORCHARD-PS by Jessica Knight, Davide Simonato, Sarah Evans, Nicola G Lovett, Jasmine Ming Gan, Aubretia McColl, Lily Elderton, Meenu Vijayakumar Sheela, John Louca, Kinza Shahab, Mary Sneade, Nycola Muchenje, Mariya Fenchyn, Sarah Tamsin Pendlebury

“…Participants are interviewed as soon as possible after admission/assessment using a structured proforma.Data are collected on demographics, diagnosis and comorbidities, social and functional background. …”
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Two New Diterpenoids Formed by Transannular Diels–Alder Cycloaddition from the Soft Coral <i>Sarcophyton tortuosum</i>, and Their Antibacterial and PPAR-β Agonist Activities by Min Sun, Songwei Li, Jianang Zeng, Yuewei Guo, Changyun Wang, Mingzhi Su

“…The structures of the new compounds were elucidated by extensive spectroscopic analysis, a quantum mechanical nuclear magnetic resonance (QM-NMR) method, a time-dependent density functional theory electronic circular dichroism (TDDFT-ECD) calculation, X-ray diffraction analysis, and comparison with the reported data in the literature. …”
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Exploration of Potential Roles of a New LOXL2 Splicing Variant Using Network Knowledge in Esophageal Squamous Cell Carcinoma by Bing-Li Wu, Guo-Qing Lv, Hai-Ying Zou, Ze-Peng Du, Jian-Yi Wu, Pi-Xian Zhang, Li-Yan Xu, En-Min Li

“…These two DEG groups were annotated by Functional Annotation Chart analysis in the DAVID bioinformatics database and compared. …”
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Ultrathin Zinc cobalt oxide nanowalls for supercapacitive energy storage applications by Bashar Aljawrneh, Borhan Aldeen Albiss, Amani Al-Othman, Muhammad Tawalbeh, Abdelelah Alshanableh, Saja Alrousan, Rawan Hayajneh

“…Supercapacitors are of particular interest due to their fast charge-discharge cycles and durability that make them ideal for portable electronic devices and renewable energy systems. While functional, supercapacitors are often fabricated from high-cost materials. …”
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CCL5/RANTES Gene Polymorphisms in Slavonic Patients with Myocardial Infarction by Irina P. Tereshchenko, Jana Petrkova, Mikhail I. Voevoda, Milos Taborsky, Zdenka Navratilova, Aida G. Romaschenko, Vladimir N. Maksimov, Frantisek Mrazek, Martin Petrek

“…The chemokine CCL5/RANTES (regulated upon activation, normal T cells expressed and secreted) is expressed in advanced atherosclerotic lesions. Functional polymorphisms of the RANTES gene can, therefore, be involved in the pathogenesis of coronary artery disease. …”
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Small vessels, big problem: a dive into the pulmonary microcirculation in pulmonary hypertension and methods for evaluation by Misha Dagan, Shane Nanayakkara, William Chan, David C. McGiffin, David M. Kaye

“…Exercise right heart catheterisation, waveform analysis, and vasoreactivity testing provide indirect insights into microvascular health, while novel invasive approaches, such as pulmonary flow reserve and pulmonary microvascular resistance indices, offer the potential for more precise functional characterisation. …”
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Identification of glucomannan molecules derived from Porang (Amorphophallus muelleri Blume) flour by various purification process and the optical transparency by Ivan Rizoputra, Sriati Wahyudi, Sudarsono, Diky Anggoro, Niniek Fajar Puspita, Risdiana, Darminto

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Dynamics of educational activity of students under the influence of digitalisation by D. Yu. Narkhov, E. N. Narkhova, D. V. Shkurin

“…Data verification was carried out using materials from the secondary data analysis of the VII stage of the regional student survey in 2016.Results. …”
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EPHX2 overexpression deters the advancement of clear cell renal cell carcinoma via lipid metabolism reprogramming by Bo Guan, Cong Huang, Cong Huang, Cong Huang, Jun He, Jun He, Jun He, Weimin Shan, Di Cui, Xiaowei Li, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang, Zongyao Hao, Zongyao Hao, Zongyao Hao

“…MethodsBulk transcriptome data, single-cell transcriptome data, and gene set data for ccRCC were sourced from the TCGA database and GEO database. …”
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HEAT SHOCK PROTEIN HSP70: PREREQUISITES FOR USE AS A MEDICINAL PRODUCT by V. M. Pokrovsky, E. A. Patrakhanov, O. V. Antsiferov, I. M. Kolesnik, A. V. Belashova, V. A. Soldatova, O. N. Pokopeiko, A. Yu. Karagodina, I. A. Arkhipov, D. G. Voronina, D. N. Sushkova

“…Heat shock protein Hsp70 is one of the main cytoprotection components under the action of various external stimuli. The analysis of the literature data shows that nowadays, the researches’ overwhelming evidence has proven the role of Hsp70 as a biological target for the drug development; however, the ideas about its use as a drug are often multidirectional.The aim of the article is to analyze and generalize the literature data on the features of the physiological functions of heat shock protein Hsp 70, and indicate the possibilities of its use for the pharmacological correction of various pathological conditions.Materials and methods. …”
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Sleep disturbance, cancer-related fatigue, and depression as determinants of quality of life among breast cancer patients undergoing chemotherapy: a cross-sectional study by Abdelaziz Hendy, Rasha Kadri Ibrahim, Amani Darwish, Saher Al Sabbah, Abeer Yahia Mahdy Shalby, Rahmah Khubrani, Amal Elhaj Alawad, Sally Mohammed Farghaly Abdelaliem, Nadia Mohamed Ibrahim Wahba

“…A total of 253 breast cancer patients undergoing chemotherapy were recruited through convenience sampling. Data were collected using validated instruments: Pittsburgh Sleep Quality Index (PSQI), Functional Assessment of Cancer Therapy-Breast (FACT-B), Cancer Fatigue Scale (CFS), and Patient Health Questionnaire-9 (PHQ-9) for depression. …”
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Insights of cellular and molecular changes in sugarcane response to oxidative signaling by Lucas Felipe Silva, Kellya F. M. Barreto, Helaine Cristiane Silva, Iara Dantas de Souza, Carlos H. S. G. Meneses, Adriana F. Uchôa, Katia C. Scortecci

“…Functional annotation through Gene Ontology and KEGG pathway enrichment showed that oxidative signaling led to the repression of photosynthesis-related pathways in leaves, while promoting pathways related to protein processing, glycolysis, and carbon metabolism in roots. …”
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Construction and validation of a cell-in-cell related prognostic signature for hepatocellular carcinoma by Hao Zhong, Dong Wang, Yisheng Chen, Danhong Zhan, Chenxi Wang, Rongqi Lin, Wen Li, Qiang Sun, Ruizhi Wang, Meifang He

“…A selection of fifty CICGs was compiled from the literature, revealing their association with CIC development through functional studies. Six predictive genes were ultimately identified through univariate Cox proportional hazards regression (Cox) and least absolute shrinkage and selection operator (LASSO) analyses. …”
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Framework for early assessment of food safety hazards in the transition to a more sustainable food system: three case studies in the Vietnamese Mekong Delta by Rosa A. Safitri, Lianne M.S. Bouwman, Marianna Siegmund-Schultze, Tri Minh Nhan, Mohammed Ariful Islam, Esther D. van Asselt, Katja C.W. van Dongen

“…The simplified approach was considered functional given the limited data for future scenarios. …”
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Exploring the connectivity of dorsolateral prefrontal cortex and the modulatory impact of transcranial magnetic stimulation in adolescents with depression: a focus on pain-related... by Dan Qiao, Yiran Li, Xiaoyu Zhang, Yujiao Wen, Xuemin Zhang, Lu Ma, Gaizhi Li, Chunxia Yang, Zhifen Liu

“…Methods Using neuroimaging data, we first compared functional connectivity (FC) of DLPFC between 60 adolescents with depression and 65 controls. …”
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Insights into the Donkey Hindgut Microbiome Using Metagenome-Assembled Genomes by Xiyan Kou, Yihong Liu, Fokun Xiang, Xinyue Zhang, Muhammad Zahoor Khan, Boxian Wu, Hua Wang, Yanlin Gong, Changfa Wang, Qingshan Ma, Yan Li

“…While reference genomes and gut microbial gene catalogs have been helpful in understanding the composition of the donkey, there is still a significant gap in sequencing and understanding the functional aspects of donkey gut microbial genomes. …”
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Quantification of rehabilitation for patients with Parkinson’s disease and related disorders using wearable devices; a proof of concept by Hikaru Kamo, Hikaru Kamo, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Koichi Nagaki, Koichi Nagaki, Koichi Nagaki, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori

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Simultaneous adsorptive removal of Pb2+, Cd2+, Cu2+, and Zn2+ using raw Norway Spruce biomass: a low-cost and eco-friendly solution for wastewater treatment by Ibrahim G. Al-Labadi, Márk Horváth, Ayah T. Alkilani, Alaa M. Al-Ma'abreh, Mohammed J. K. Bashir, Basem E. Keshta, Basem E. Keshta, Ghadir Hanbali, Wail Al Zoubi, Mostafa R. Abukhadra, Mostafa R. Abukhadra, Haifa A. Alqhtani, Mohamed Hamdy Eid, Mohamed Hamdy Eid

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Succinylation-related molecular activities in cancer: metabolic adaptations, immune landscape, and prognostic significance in colorectal cancer by Zhihang Jiang, Zhihang Jiang, Xiaoqing Li, Xiaoqing Li, Long Hu, Zheng Jiang

“…A systematic pan-cancer analysis of succinylation-related molecular activities is needed.MethodsBulk transcriptomic, single-cell RNA sequencing, and spatial transcriptomic data across pan-cancer from TCGA, GEO, TISCH, and multiple other databases were analyzed. …”
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Longitudinal sequencing of cardiometabolic multimorbidity among older adults and association with subsequent dementia onset. by Corey L Nagel, Siting Chen, Heather G Allore, Anda Botoseneanu, Jason T Newsom, Nick Bishop, David A Dorr, Jeffrey Kaye, Ana R Quiñones

“…<h4>Background</h4>Patterns of development of cardiometabolic multimorbidity (CMM) and the impact of specific cardiometabolic disease combinations on cognitive function are not well understood. This study utilizes sequence analysis to describe the ordering and timing of cardiometabolic disease accumulation over a five-year period and to assess both sociodemographic predictors and cognitive outcomes of typical cardiometabolic disease sequences.…”
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