Accuracy of warm ischemia time measurement using a surgical intelligence software in partial nephrectomies: A validation study by Archan Khandekar, Joao G. Porto, Jean C. Daher, Pedro F. S. Freitas, Dotan Asselman, Maritza M. Suarez, Mark L. Gonzalgo, Dipen J. Parekh, Sanoj Punnen

“…Abstract Objectives The objectives of this study are to compare the accuracy of warm ischemia times (WITs) derived by a surgical artificial intelligence (AI) software to those documented in surgeon operative reports during partial nephrectomy procedures and to assess the potential of this technology in evaluating postoperative renal function. Patients and methods A surgical AI software (Theator Inc., Palo Alto, CA) was used to capture and analyse videos of partial nephrectomies performed between October 2023 and April 2024. …”
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Omalizumab for Chinese patients with moderate-to-severe allergic asthma in real-world clinical setting: a prospective, observational study by Wen Wang, Yue Guo, Jieying Li, Congying Zou, Lifang Zhao, Ya Zhu, Feiran Wang

“…Omalizumab was administered subcutaneously, and the investigator collected real-world data on exacerbations, steroid exposure, pulmonary function and laboratory assessments at weeks 16, 24, 52, 104 and 156 after treatment initiation. …”
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Hsa_circ_0072088 promotes non-small cell lung cancer progression through modulating miR-1270/TOP2A axis by Sixuan Li, Zhigang Cui, Min Gao, Yanan Shan, Yihong Ren, Yuxin Zhao, Di Wang, Tingyu Meng, Hongxu Liu, Zhihua Yin

“…Abstract According to the data released by the International Agency for Research on Cancer (IARC) in 2020, lung cancer ranks second among newly diagnosed malignant tumors globally. …”
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Escherichia coli aggravates inflammatory response in mice oral mucositis through regulating Th17/Treg imbalance by Jia Liu, Jia Liu, Jia Liu, Wenhui Xia, Wenhui Xia, Wenhui Xia, Wenhui Xia, Juehua Cheng, Juehua Cheng, Juehua Cheng, Yanlin Geng, Yanlin Geng, Yanlin Geng, Weiping Li, Weiping Li, Weiping Li, Yuan Fan, Yuan Fan, Yuan Fan

“…Differential gene expression analysis, functional enrichment analysis and immune infiltration analysis were performed using RNA-seq data from oral lichen planus (OLP).ResultsE. coli stimulation aggravated inflammatory responses induced by scratching in lingual mucosa of mice, including increased local and systemic expression of interleukin 6 (IL6), interleukin 17 (IL17), chemokine receptor 6 (CCR6) and chemokine C-C motif ligand 20 (CCL20), increased proportions of Th17 cells and increased Th17/Treg ratio in spleen lymphocytes. …”
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Comparison of Erythrocyte Membrane Lipid Profiles between NAFLD Patients with or without Hyperlipidemia by Wenbin Chen, Shanshan Shao, Hu Cai, Jie Han, Tian Guo, Yilin Fu, Chunxiao Yu, Meng Zhao, Tao Bo, Zhenyu Yao, Jiajun Zhao, Qunye Zhang, Guowang Xu, Chunxiu Hu, Ling Gao

“…Lipid was extracted from the erythrocyte membrane, and lipid profiles of subjects were analyzed by liquid chromatography mass spectrometry (LC-MS). Results. Data sets from 103 subjects were adopted for lipidomic analysis. …”
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Alterations of diffusion kurtosis measures in gait-related white matter in the “ON–OFF state” of Parkinson’s disease by Xuan Wei, Shiya Wang, Mingkai Zhang, Ying Yan, Zheng Wang, Wei Wei, Houzhen Tuo, Zhenchang Wang, Ting Gao

“…Preprocessing of diffusion-weighted data was performed with Mrtrix3 software, using a directional distribution function to track participants’ main white matter fiber bundles. …”
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Sex-specific differences in preclinical models of advanced chronic liver disease and portal hypertension by Peio Aristu-Zabalza, María Andrés-Rozas, Zoe Boyer-Díaz, David P. Al-Adra, Douglas Maya-Miles, Sergi Guixé-Muntet, Anabel Fernández-Iglesias, Jordi Gracia-Sancho

“…No differences were observed in hepatic microvascular function. In the BDL model, females had more fenestrae and porosity, and less fibrosis. …”
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Influence of heart rate variability on platelet hemostasis by average aggregate size in patients with chronic coronary heart disease in combination with COVID-19 by V.Z. Netiazhenko, S.Ye. Mostovyi

“…In СAD and COVID-19, platelet hemostatic function is impaired, as confirmed by laser aggregometry data. …”
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Immediate Postoperative Insulin Requirements May Predict Metabolic Outcome after Total Pancreatectomy and Islet Autotransplantation by Neha Verma, Amer Rajab, Jill Buss, Luis Lara, Kyle Porter, Philip Hart, Darwin Conwell, W. Kenneth Washburn, Sylvester Black, Kristin Kuntz, Shumei Meng

“…In this single-center retrospective study, we report pre-TPIAT characteristics, beta cell function indices, islet yield, and post-TPIAT glucose management data to further understand their relationship. …”
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The role and mechanism of CLEC7A in regulating PD-L1 to promote ovarian cancer growth by CHEN Yao, SUN Sibai, XU Jun, HE Jie

“…In a mouse tumor model with high CLEC7A expression， the proportion of myeloid-derived suppressor cells （MDSCs） and CD8⁺T cells， as well as the functional changes of MDSCs， were observed. Results Transcriptional regulatory network analysis revealed that forkhead box protein P3 （FOXP3） and CLEC7A both regulate immune-related genes. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi, Dalia Ali, Radhakrishnan Vishnubalaji, Muthurangan Manikandan, Muhammad Atteya, Abdulaziz Siyal, Musaad Alfayez, Abdullah Aldahmash, Moustapha Kassem, Nehad M. Alajez

“…Stem cell signaling small molecule library functional screen was performed employing human bone marrow skeletal (mesenchymal) stem cells (hBMSCs). …”
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Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease by Zhen Zhu, Guangxin Luan, Song Wu, Yiyi Song, Shuang Shen, Kaiyue Wu, Shengnan Qian, Weiping Jia, Jun Yin, Tao Ren, Jianping Ye, Li Wei

“…To reveal the effects of losartan on gene function and pathway changes in renal tubular mitochondria, Gene Ontology (GO) enrichment analysis and GSEA/GSVA scoring were performed to analyze the specific response of proximal tubular (PT) cell mitochondria to losartan treatment, including key events in mitochondrial homeostasis such as mitochondrial morphology, dynamics, mitophagy, autophagic flux, mitochondrial respiratory chain, apoptosis, and ROS generation. …”
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Regression models for the prediction of the influence of magnesium ions on primary endothelial cell (HUVEC) proliferation and migration by Heike Helmholz, Redon Resuli, Marius Tacke, Jalil Nourisa, Sven Tomforde, Roland Aydin, Regine Willumeit-Römer, Berit Zeller-Plumhoff

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Integration of single-cell transcriptomics and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of nucleotide metabolism in lung adenocarcinoma by Kai Zhang, Kai Zhang, Luyao Wang, Huili Chen, Lili Deng, Mengling Hu, Ziqiang Wang, Yiluo Xie, Chaoqun Lian, Xiaojing Wang, Xiaojing Wang, Jing Zhang

“…In addition, patients of different subtypes showed significant differences in genomic mutation and functional enrichment and exhibited different anti-tumor immune profiles. …”
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Cacao Agroforestry in Mahakam Ulu: Transformation Strategy from Traditional to Good Agricultural Practices and Smart Agroforestry System by Catur Budi Wiati, Eddy Mangopo Angi, Karmilasanti Karmilasanti, Murniati Murniati, Sri Suharti, Indra A.S.L.P. Putri, Aris Pudji Hadi, Muhammad Furkan, Belasius Anyeq, Krista Tala, Veronica Carolina, Awaluddin Aziz, Ria Andiana, Yuliara Limbong, Yosua Naibaho, Mukrimin Mukrimin

“…Data were processed using qualitative descriptive analysis, gender, and SWOT analysis. …”
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A mono-center clinical study on clinical pathological features and prognosis of adult idiopathic membranous nephropathy by CHEN Jing, LIAO Yun-juan, JIANG Hong-ying, LI Ji-sai, LI Luo-hua, LI Jing

“…Methods Retrospective analysis was performed on the clinical and pathological data of 83 patients diagnosed with IMN by renal puncture biopsy in the department of nephrology, the Second Hospital Affiliated to Kunming Medical University from January 2015 to December 2017, and eGFR<30 mL·min^-1·（1.73 m²）^-1 was used as the end point of follow-up to analyze the follow-up data of the patients. …”
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Is avoidable diabetes-related hospitalization in older patients with type 2 diabetes mellitus associated with increased health expenditure?: A nationwide retrospective cohort study... by Woo-Ri Lee, Gyeong-Min Lee, Noorhee Son, Kyu-Tae Han, Sungyoun Chun, Yehrhee Son, Ki-Bong Yoo

“…The outcome measures included one- and five-year health expenditures. Regression analysis was performed using the generalized estimating equation (GEE) with a gamma distribution and log-link function. …”
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Protocol for the air purification for eosinophilic COPD study (APECS): a randomised controlled trial of home air filtration by HEPA by Mary B Rice, Petros Koutrakis, Brent A Coull, Wanda Phipatanakul, Kimberly F Greco, Ilona Jaspers, Meghan E Rebuli, Muhammad S Saeed, Cailey M Denoncourt, Isabella A Chao, Sophia Schortmann, Nicholas J Nassikas, Andrew J Synn, Choong-Min Kang, Jack M Wolfson, Stephen T Ferguson, Jessica P Liu

“…Introduction Exposure to particulate matter (PM) pollution has been associated with lower lung function in adults with chronic obstructive pulmonary disease (COPD). …”
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Coordinate regulation of G protein signaling via dynamic interactions of receptor and GAP. by Marc Turcotte, Wei Tang, Elliott M Ross

“…The work also demonstrates the applicability of appropriately data-constrained system-level analysis to signaling networks of this scale.…”
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JNK pathway suppression mediates insensitivity to combination endocrine therapy and CDK4/6 inhibition in ER+ breast cancer by Sarah Alexandrou, Christine S. Lee, Kristine J. Fernandez, Celine E. Wiharja, Leila Eshraghi, John Reeves, Daniel A. Reed, Neil Portman, Zoe Phan, Heloisa H. Milioli, Iva Nikolic, Antonia L. Cadell, David R. Croucher, Kaylene J. Simpson, Elgene Lim, Theresa E. Hickey, Ewan K. A. Millar, Carla L. Alves, Henrik J. Ditzel, C. Elizabeth Caldon

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