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14441
A machine learning-based approach to predict depression in Chinese older adults with subjective cognitive decline: a longitudinal study
Published 2025-07-01“…Three machine learning models—Gradient Boosting, Random Forest, and Boosted XGBoost—were used to predict depression risk over three years, incorporating 10 demographic, 5 health, 13 chronic disease, 3 lifestyle, and 2 physical function factors. Lasso feature selection identified 10 key variables for model training. …”
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14442
EEG-based characterization of auditory attention and meditation: an ERP and machine learning approach
Published 2025-08-01“…The integration of EEG biomarkers with machine learning methods emerges as a potential pathway for real-time cognitive and emotional state monitoring which enables tailored interventions through neurofeedback systems and brain–computer interfaces to boost cognitive function and emotional health across clinical settings and everyday life.…”
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14443
Relationships of PGRN with sTREM2 in AD continuum and non-AD pathophysiology and their reciprocal roles in modulating amyloid pathology: two population-based study
Published 2025-07-01“…These findings suggest that the interplay between lysosome function and microglia-related neuroinflammation plays key roles in amyloid metabolism.…”
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14444
Association of blood urea nitrogen with 28-day mortality in critically ill patients: A multi-center retrospective study based on the eICU collaborative research database.
Published 2025-01-01“…<h4>Objective</h4>Blood urea nitrogen (BUN) is a commonly used biomarker for assessing kidney function and neuroendocrine activity. Previous studies have indicated that elevated BUN levels are associated with increased mortality in various critically ill patient populations. …”
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14445
Revealing the Immune Response of <i>Sitona callosus</i> Gyllenhal to Entomopathogenic Fungi <i>Beauveria bassiana</i> Infection Through Integrative Analyses of Transcriptomics and...
Published 2024-11-01“…Transcriptomic and metabolomic analyses were conducted to explore alterations in gene expression and metabolic processes in <i>S. callosus</i> at 48, 96, and 144 h post infection with <i>B. bassiana</i>. The transcriptomic analysis unveiled that <i>B. bassiana</i> infection boosted immune responses in tubercula, affecting carbohydrate metabolism, cytochrome P450 activity, lysosome function, apoptosis regulation, phagosome formation, glutathione metabolism, amino acid metabolism, and pathogen response pathways. …”
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14446
Perceived social support on objective measured sedentary behavior of stroke patients: the mediating role of exercise self-efficacy
Published 2024-09-01“…IntroductionAs stroke patients may have impaired motor function, there may have increased sedentary behavior. …”
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14447
Semi-analytical modeling and multi-objective optimization of horizontal-well deep borehole heat exchangers
Published 2025-08-01“…Model accuracy was validated against experimental data and 3-D numerical simulations. A Monte-Carlo uncertainty-propagation scheme combined with Pearson correlation analysis reveals that solid-phase thermal conductivities main dominate thermal performance. …”
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14448
Double-transmitting and Sextuple-receiving Borehole Transient Electromagnetic Method and Experimental Study
Published 2017-04-01“…In this paper, the response equations of the transmitting-receiving mode of double-transmitting and sextuple-receiving borehole TEM are deduced, and the response characteristics of the induction segment and the attenuation segment of the receiving loops are obtained based on the response equations under ramp function turn-off condition, providing the basis for theoretical analysis. …”
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14449
Changes in the miRNA-mRNA Regulatory Network Precede Motor Symptoms in a Mouse Model of Multiple System Atrophy: Clinical Implications.
Published 2016-01-01“…We investigated the expression patterns of miRNAs and their mRNA targets in substantia nigra (SN) and striatum, two brain regions that undergo neurodegeneration at a later stage in the MSA model, by microarray and RNA-seq analysis, respectively. Analysis was performed at a time point when α-synuclein accumulation was already present in oligodendrocytes at neuropathological examination, but no neuronal loss nor deficits of motor function had yet occurred. …”
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14450
Airport microgrid control using integral-of-absolute-error having high renewable penetration
Published 2025-07-01“…Firstly, the overall transfer function (OATrFn) for AP $${\mu }G_{d}$$ system is obtained by modeling and combining each component. …”
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14451
Paracoccidoides brasiliensis 30 kDa adhesin: identification as a 14-3-3 protein, cloning and subcellular localization in infection models.
Published 2013-01-01“…These proteins are a conserved group of small acidic proteins involved in a variety of processes in eukaryotic organisms. However, the exact function of these proteins in some processes remains unknown. …”
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14452
Effects of Aerobic Exercise on Gene Expression of Skeletal Muscle Related to Aging and Prevention of Chronic Diseases in the Elderly
Published 2025-07-01“…A total of 619 differential genes were screened out between the elderly aerobic exercise group and the non-exercise group. GO enrichment analysis shows the effect of aerobic exercise on the biological process, cellular localization, and molecular function in the elderly, mainly on muscle development, actin cytoskeleton, and actin binding. …”
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14453
Research on Feature Extraction of Performance Degradation for Flexible Material R2R Processing Roller Based on PCA
Published 2020-01-01“…To handle the problem of high-dimensional performance characterization and complexity of calculating the performance indicators in flexible material roll-to-roll processing, this paper proposes a PCA method for extracting the degradation characteristic of roll shaft. Based on the analysis of the performance influencing factors of flexible material roll-to-roll processing roller, a principal component analysis extraction model was constructed. …”
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14454
Unveiling the effects of electric field treatments on crop cultivation: a game-changing sustainable energy strategy for plant pathogen eradication and boosting yield growth in agri...
Published 2025-06-01“…Live controlled by the Internet of Things (IoT) using microscopy image analysis and Programmable DC Power Supply (PDPS) digital data. …”
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14455
Identifying the mitochondrial ribosomal protein MRPL13 as an oncogenic RBP that promotes proliferation, migration, and anti-apoptotic effects in esophageal cancer cells
Published 2025-05-01“…Methods: TCGA-ESCA, IMvigor-210 and GSE53624 repositories were used to obtain esophageal cancer omics data and clinical information. Differential expression analysis, protein-protein interaction and LASSO methods were used to construct the risk signature. …”
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14456
Influence of metabolic syndrome in the occurrence of hearing disorders in the Democratic Republic of Congo
Published 2025-03-01“…Sociodemographic, clinical, and biological data were analyzed. Multivariate logistic regression analysis and discriminant analysis were used as a basis to document the factors associated with hearing disorders in the study population; and the statistical significance threshold was p < 5 %. …”
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14457
The theoretical cognition and research paradigm of land system science
Published 2025-01-01“…The research paradigm of land system science has gradually transformed from knowledge and phenomenon description to the simulation and prediction of complex land systems, which emphasizes the integration of multidisciplinary theories and methods as well as understanding the local-distant coupled interactions of land systems based on the integrated multiscale analysis of expanding boundaries, and focuses on the construction of large-scale quantitative land system models to provide comprehensive and dynamic integrated analysis, prediction and simulation of its dynamic mechanisms, integrated effects and future scenarios and risks, and appeals for an opening scientific collaboration in the era of big data.…”
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14458
A study on the estrogenic effects of Benzophenone-2 in adult ovariectomized mice
Published 2025-04-01“…Due to rising infertility issues and scarce scientific data on its effect on female reproductive health, this study aimed to investigate the possible estrogenic effects of BP2 in adult female mice following bilateral ovariectomy. …”
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14459
Same words, different meanings: examining curriculum making from the perspective of language teachers’ epistemic beliefs
Published 2025-05-01“…We used interpretative phenomenological analysis to uncover teachers’ implicit epistemic beliefs by probing into their interpretations of the curriculum’s teaching goals and learning principles.ResultsThematic analysis revealed three major misalignments relating to the function of literacy in the lives of language learners, the features of literacy, and the fields of responsibility of teachers and learners. …”
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14460
Joint ancestry and association testing in admixed individuals.
Published 2011-12-01“…We detected loci at 1q24 and 6q26 as genome-wide significant via admixture mapping; both loci have been independently reported from linkage analysis. Using the association data, we resolved the 1q24 signal into two regions. …”
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