Sex-based inequalities in contemporary UK hospital management of stable chest pain by Matthias Schmitt, Michelle Claire Williams, Margaret Loudon, Russel Bull, Stelios Iacovides, Gareth Morgan-Hughes, Carl A Roobottom, Alice Veitch, Franchesca Wotton

“…We looked for sex-related differences in referral to computed tomographic coronary angiography (CTCA) and subsequent functional imaging (FI), invasive coronary angiography (ICA) and revascularisation.Methods This was a prospective analysis of CTCA practice in 8 UK centres between 2018 and 2020. …”
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Resources, Potentials and Academic Achievements of Students. Part 1. Differentiation of Resources and Potentials by L. Ya. Dorfman, A. Yu. Kalugin

“…The external prerequisites include structural and functional organisation, educational environment. The internal prerequisites consist of cognitive factors – intelligence, creativity, and non-cognitive factors – self-efficacy, self-control, motivation, expectations and goal setting. …”
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TOPICAL ISSUES OF DIAGNOSIS AND TREATMENT OF INFERTILITY IN WOMEN WITH INTERNAL GENITAL ENDOMETRIOSIS by A. M. Medzhidova, A. E. Esedova

“…A systematic review and meta-analysis of data obtained with transvaginal ultrasound and MRI in women with histologically confirmed adenomyosis showed a similarly high level of accuracy of diagnosis, but an important advantage of MRI was the standardization of images. …”
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Promoting healthy ageing through measures addressing social determinants of older adults’ health: a scoping review protocol by Rima Kaddoura, Zeinab Hassan, Khairat Al-Habbal, Sara Yousef, Ola El Zein

“…The WHO defines healthy ageing as maintaining functional ability and well-being in later life, emphasising holistic health beyond disease absence. …”
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Predicting loss of independence among geriatric patients following gastrointestinal surgery by Michaela R. Cunningham, Christopher L. Cramer, Ruyun Jin, Florence E. Turrentine, Victor M. Zaydfudim

“…Primary outcome was loss of independence – discharge to facility other than home and decline in functional status. Patients from 2014 to 2017 comprised the training data set. …”
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Prevalence and Pattern of Chronic Musculoskeletal Pain among Older Adults and its Sociodemographic and Pain Intervention Correlates in a Tertiary Hospital in North Central Nigeria by Oluwatoyin A. Abolarin, Samuel A. Adefemi, Adetutu Babalola, Mustapha Mamman, Philip N. Gara, Ezekiel U. Sheshi, Yusuf Ibrahim

“…However, there is a paucity of local data on the prevalence and pattern of CMP in the elderly. …”
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Transcriptomic Analyses Reveal Light-Induced Anthocyanin Accumulation in <i>Lycium ruthenicum</i> Murray by Shengrong Chen, Tao He, Wenyi Gu, Ruimin Li, Yinyan Qi

“…Anthocyanins found in <i>Lycium ruthenicum</i> Murray are crucial for the plant’s defense against UV light and environmental stress, as well as for their economic value in functional foods and nutraceuticals due to their high antioxidant content. …”
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De novo genome hybrid assembly and annotation of the endangered and euryhaline fish Aphanius iberus (Valenciennes, 1846) with identification of genes potentially involved in salini... by Alfonso López-Solano, Ignacio Doadrio, Tessa Lynn Nester, Silvia Perea

“…Results A hybrid assembly approach was employed, integrating PacBio long-read sequencing with Illumina short-read data. In addition to the assembly, an extensive functional annotation of the genome is provided by using AUGUSTUS, and two different approaches (InterProScan and Sma3s). …”
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Unveiling PANoptosis in Acute Kidney Injury: An Integrative Multi-Dimensional Approach to Identify Key Biomarkers by Wang N, Zhang L, Xu Z, Xu Q, Lu Y, Niu P, Yan L, Wang L, Cao H, Shao F

“…The diagnostic potential of these genes was demonstrated with the area under curve values of 0.981 for EGR1, 0.920 for CEBPD, 0.968 for HSPA1A, 0.970 for HSPA1B, and 0.953 for RHOB. Functional enrichment analysis demonstrated a significant positive correlation between the expression of these biomarkers and PANoptosis activity. …”
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Fibromyalgia Patients Have Markedly Greater Postoperative Opioid Use and Emergency Department Visits Following Bunionectomy by Andrew Sauer BA, Jung Yoo MD, Lara Atwater MD

“…This deformity typically has favorable surgical outcomes, but it can cause significant pain, functional limitations, and decreased quality of life if untreated. …”
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Regulatory role of CD177+ neutrophils in BMP signaling pathway and its implications for inflammatory bowel disease, sepsis, and intestinal tumors by Lin Yu, Haoyue Zhang, Ling Jia, Detian Lai, Lina Jia, Qingzhu Li, Enwei Guo, Feng Yang, Bingyu Zhang, Qiancheng Luo

“…Bioinformatics methods like background correction, normalization, and differential expression analysis were used. Weighted gene co-expression network analysis (WGCNA), gene functional enrichment analysis, pan-cancer analysis, single-cell analysis, and in vitro experiments including Caco-2 cell culture, cell proliferation assay (CCK-8), flow cytometry apoptosis analysis, quantitative real-time PCR (qRT-PCR), and plate colony formation assay were performed. …”
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Machine learning-derived diagnostic model of epithelial ovarian cancer based on gut microbiome signatures by Cheng Chen, Chengyuan Deng, Yanwen Li, Shuguang He, Yunhong Liu, Shuwen Pan, Wenqian Xu, Lu Fang, Yixi Zhu, Yingying Wang, Xiaoxin Jiang

“…Fecal samples were collected, followed by sequencing of the V3–V4 region of the 16S rRNA gene. The clinical data and pathological characteristics were comprehensively recorded for further analysis, PICRUSt2 was utilized to conduct an analysis of microbial functional predictions, WGCNA networks were constructed by integrating microbiome and clinical data. …”
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Lactylation associated biomarkers and immune infiltration in aortic dissection by Jianfeng Ye, Yuntao Fu, Yuanjia Ke, Huanting Liu, Sini Fang, Yumeng Lei, Ying Mao, Liqiu Yan, Youcheng Wang

“…Functional enrichment analyses were performed, and Weighted Gene Co-expression Network Analysis (WGCNA) was utilized to identify gene modules associated with AD. …”
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Modulation of copper homeostasis and cuproptosis by PDHA1 in acute myeloid leukemia by Tianping Chen, Nan Wei, Wenxiu Lv, Lijun Qu, Qian Qu, Chaohong Wu, Yuan Ling, Haipeng Liu, Hongjun Liu

“…This study investigates the expression and functional significance of CRGs, particularly PDHA1, in AML progression and cuproptosis regulation Methods We integrated bioinformatics analysis and experimental validation. …”
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Single-cell sequencing reveals cell heterogeneity and aberrantly activated pathways associated with microvascular invasion in hepatocellular carcinoma by Jianwei Cui, Fanyi Zeng, Ming Tang, Ming Tang, Shiwu Yin, Shiwu Yin

“…This study aims to explore these aspects using single-cell transcriptomic analysis.MethodsThe present study utilized single-cell transcriptomic data from public databases to conduct an in-depth transcriptome analysis of tumour tissues and adjacent nontumor tissues from five patients with hepatocellular carcinoma, with a particular focus on samples from three patients exhibiting microvascular invasion. …”
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BrGSTF12, an anthocyanin-related glutathione S-transferase gene, is essential for light-induced anthocyanin accumulation in zicaitai (Brassica Rapa Var. purpuraria) by Mei Fu, Guihua Li, Mengting Lu, Shizheng Jiang, Umer Karamat, Imran Khan, Juxian Guo

“…Bioinformatics approaches were employed to predict and identify potential genes involved in the sequestration of anthocyanins in Zicaitai (Brassica rapa var. purpuraria) utilizing data from the transcriptome database. Results In this study 0-hour light (dark) and 8-hour light treatments of Zicaitai were examined using transcriptome analysis. …”
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Neural Network-Based Predictive Control of COVID-19 Transmission Dynamics to Support Institutional Decision-Making by Cristina-Maria Stăncioi, Iulia Adina Ștefan, Violeta Briciu, Vlad Mureșan, Iulia Clitan, Mihail Abrudean, Mihaela-Ligia Ungureșan, Radu Miron, Ecaterina Stativă, Michaela Nanu, Adriana Topan, Ioana Nanu

“…This research primarily focuses on designing a control technique that incorporates the five most important inputs that impact the spread of COVID-19 on the Romanian territory. Quantitative analysis and data filtering are two crucial aspects to consider when developing a mathematical model. …”
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Interaction of brain imaging features and effects of intensive blood pressure lowering after endovascular treatment for acute ischaemic stroke: the pre-specified secondary analyses... by Xiaoxi Zhang, Xinwen Ren, Yongxin Zhang, Yongwei Zhang, Lei Zhang, Hongjian Shen, Zifu Li, Pengfei Xing, Ping Zhang, Weilong Hua, Fang Shen, Bing Tian, Wenhuo Chen, Hongxing Han, Liyong Zhang, Chenghua Xu, Tong Li, Yu Gao, Yu Zhou, Qiao Zuo, Dongwei Dai, Rui Zhao, Qiang Li, Qinghai Huang, Yi Xu, Xiaoying Chen, Qiang Li, Lili Song, Craig S. Anderson, Pengfei Yang, Jianmin Liu

“…Multivariable logistic regression analysis was done according to the modified intention-to-treat principle in all participants with available outcome data. …”
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Decision-Making Process of Home and Social Care Professionals Using Telemonitoring of Activities of Daily Living for Risk Assessment: Embedded Mixed Methods Multiple-Case Study by Renée-Pier Filiou, Mélanie Couture, Maxime Lussier, Aline Aboujaoudé, Guy Paré, Sylvain Giroux, Hubert Kenfack Ngankam, Patricia Belchior, Carolina Bottari, Kevin Bouchard, Sébastien Gaboury, Charles Gouin-Vallerand, Faustin Armel Etindele Sosso, Nathalie Bier

“…Data analysis showed a 4-step decision-making process used by clinicians: (1) extraction of relevant telemonitoring data, (2) comparison of telemonitoring data with other sources of information, (3) risk assessment of the care recipient’s ADL performance and ability to remain at home, and (4) maintenance or modification of the intervention plan. …”
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Immune-related gene characterization and biological mechanisms in major depressive disorder revealed based on transcriptomics and network pharmacology by Shasha Wu, Shasha Wu, Qing Jiang, Jinhui Wang, Jinhui Wang, Daming Wu, Yan Ren

“…Functional enrichment pathway analysis indicated that these differential genes were associated with immune functions. …”
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