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13921
A Modified Nonlinear Mohr–Coulomb Failure Criterion for Rocks Under High-Temperature and High-Pressure Conditions
Published 2025-07-01“…This criterion incorporates a quadratic function of confining pressure to account for the attenuation rate of strength increase under high confining pressure and a linear function of temperature to reflect the linear degradation of strength at elevated temperatures. …”
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13922
Determinants of Anemia Among Patients with Chronic Kidney Disease: A Systematic Review of Empirical Evidence
Published 2025-06-01“…Methodological quality was assessed using the Joanna Briggs Institute (JBI) critical appraisal checklists tailored to each study design, and data synthesis was performed using convergent thematic analysis.Results: Of 2269 records initially identified, 21 studies met inclusion criteria. …”
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13923
Comprehensive transcriptome, miRNA and kinome profiling identifies new treatment options for personalized lung cancer therapy
Published 2025-03-01“…Inhibition of kinases which function as master regulators disrupted the signalling networks, and their gene knock‐down studies confirmed inhibition of cell proliferation in a panel of human LC cell lines. …”
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13924
Pathogenetic therapy of mitral valve prolapse
Published 2025-02-01“…To evaluate the effect of angiotensin II receptor blocker (ARB) therapy on the expression of transforming growth factor-β (TGF-β) in the myxomatous mitral valve, on the serum levels of TGF-β1/TGF-β2 and the left ventricular (LV) systolic function in patients with mitral valve prolapse (MVP).Material and methods. …”
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13925
Characteristics of the Parameters of Somatic Construction and Fitness Level in Elderly People Based on Selected Fullerton Test Samples
Published 2015-06-01“…Aging should be understood, however, as a progressive deterioration of the function of organs and systems caused by the passage of time, which leads to a reduction of adaptability in stressful situations. …”
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13926
Assessment of historical and future changes in temperature indices for winegrape suitability in Hungarian wine regions (1971–2100)
Published 2025-02-01“…To address these changes, we analysed the temporal changes of four temperature indicators: Average Growing Season Temperature (AGST), Growing Degree Days (GDD or Winkler index (GDD-WI), Huglin index (HI), and Biologically Effective Degree Days (BEDD) across 22 Hungarian wine regions from 1971 to 2100. The analysis was based on data from 14 climate models under RCP 4.5 and RCP 8.5 scenarios. …”
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13927
Targeting GJB4 to inhibit tumor growth and induce ferroptosis in pancreatic cancer
Published 2025-06-01“…The effects on tumor cell proliferation, invasion, and metastasis were assessed using cell proliferation assays, Transwell migration assays, wound healing assays, and subcutaneous xenograft models. Bioinformatics analysis was conducted to explore the function of GJB4 in PC cells. …”
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13928
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13929
Identification of a key smooth muscle cell subset driving ischemic cardiomyopathy progression through single-cell RNA sequencing
Published 2025-07-01“…In this study, we established that the C6 S100A4+ SMCs subpopulation is critical by performing an integrated single-cell analysis of the known publicly available data GSE145154. …”
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13930
Current aspects of treatment and rehabilitation of patients with pharyngeal cancer
Published 2016-06-01“…Treatment of patients with stage T1–2 and in some patients with stage T3 includes the following methods: radiotherapy, chemoradiotherapy, endolaryngeal surgery with laser, photodynamic therapy, open functionally sparing operations. According to the data of the authors, today currently there is no common algorithm for treatment of stage T1–3 pharyngeal malignant neoplasms.Locally disseminated tumors of the throat and laryngopharynx, corresponding to stages T3–4N0–2M0 as a rule are treated by combined management with pre- or postoperative irradiation. …”
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13931
Using Image-based AI for insect monitoring and conservation - InsectAI COST Action
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13932
Single-stage surgery with antibiotic-loaded hydrogel-coated implants versus two-stage surgery for chronic periprosthetic hip joint infection in French tertiary referral hospitals:...
Published 2025-02-01“…The single-stage procedure is thought to be less susceptible to late functional complications with a shorter, single hospital stay. …”
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13933
A hybrid model for short-term offshore wind power prediction combining Kepler optimization algorithm with variational mode decomposition and stochastic configuration networks
Published 2025-07-01“…Finally, a multi-seasonal and multi-scenario wind power forecasting analysis is conducted by using an actual data set from an offshore wind farm in China. …”
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13934
Sexually dimorphic impact of prenatal hyperandrogenism on offspring growth trajectory in sheep
Published 2025-07-01“…Growth trajectory, systemic cytokines, and metabolomics were analyzed in the postnatal cohort. Data was analyzed using mixed model ANOVA, student T-test, and Cohen D (d) analysis. …”
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13935
Protective Effect of Aerobic Training and Royal Jelly on Cellular senescence Markers of Cardiomyocytes in Obese Rats
Published 2022-06-01“…Data analysis using two-way analysis of variance showed that AT and RJ significantly reduced the expression of p16 (P = 0.000 and P = 0.000, respectively) and p21 (P = 0.000 and P = 0.000, respectively) cardiomyocytes in HFD rats. …”
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13936
Feasibility and Safety of Anlotinib Combined with Immune Checkpoint Inhibitors in Patients with Previously Immunotherapy-Treated Extensive-Stage Small Cell Lung Cancer: A Retrospec...
Published 2025-06-01“…Anlotinib was administered at a standard dosage, ICIs regimens included PD-1 inhibitors (Tislelizumab, 200 mg; serplulimab, 4.5 mg/kg) and PD-L1 inhibitors. Efficacy and safety data during treatment were retrospectively collected, and patients were followed up regularly to obtain long-term survival data. …”
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13937
Sjögren’s syndrome is associated with a reduction in the surface area of the right caudal anterior cingulate gyrus
Published 2025-07-01“…We also used CELLECT to leverage genome-wide association study (GWAS) and single-cell RNA sequencing (scRNA-seq) data to identify pathogenic cell types. Results The MR analysis revealed a negative genetic causal relationship between SS and brain structure (entorhinal: IVW: beta = − 3.4398, SE = 1.6954, P = 0.0425; caudal anterior cingulate gyrus: IVW: beta = − 4.2947, SE = 2.0593, P = 0.0370). …”
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13938
Investigating the acute cognitive effects of dietary compounds using fNIRS: methodological limitations and perspectives for research targeting healthy adults
Published 2024-12-01“…This review proposes recommendations to enhance current methodologies in the research field, focusing on key aspects of the data collection phase, including research design, experimental paradigms, and participant demographics, and their integration into the analysis phase. …”
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13939
Concept and Design of Cutting Tools for Osseodensification in Implant Dentistry
Published 2024-12-01“…Thereon, the structural model of osseodensification bur is first represented as a hypergraph. Based on the analysis of previous research, functional relationships between design parameters of osseodensification burs, osseodensification procedure conditions, and procedure performance data were established and, for the first time, described in the comprehensive form of a hypergraph. …”
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13940
Microsurgical treatment of recurrent and residual previously clipped/or coiled intracranial aneurysms: a single center series of 22 patients
Published 2025-10-01“…There was a total of 11 previously coiled and 12 previously clipped aneurysms. Data on demography, previous treatments, aneurysm characteristics, surgical indications, microsurgical treatment strategy, post-surgical occlusion rate, durability of treatment, complications, and functional outcome were collected. …”
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