Mechanism-based modular psychotherapy versus cognitive behavioural therapy for adolescents and young adults with childhood trauma experiences: study protocol for a feasibility tria... by Till Bärnighausen, Hanna Zimmermann, Christian Schmahl, Stephanie Bauer, Beate Ditzen, Hans-Christoph Friederich, Markus W Haun, Astrid Berner-Rodoreda, Elisabeth Schramm, Svenja Taubner, Corina Aguilar-Raab, Sabine C Herpertz, Manuel Feisst, Frank Enning, Katja I Seitz, Niklas Schouler, Jan Hundertmark, Maximilian Wilhelm, Svea Franz, Christoph W Korn, Ruben Vonderlin, Eva Vonderlin, Josef Bailer, Elias Bopp, Sophia von Stockert, Laura Tabea Kristalis, Claudia Calvano

“…This proof-of-concept study aims to provide initial evidence for acceptability, feasibility and changes in self-rated and diagnostician-rated psychopathology (post-treatment and 3 months follow-up) of MeMoPsy and elucidate the mechanisms of change using psychotherapy process research, Ecological Momentary Assessment and functional magnetic resonance imaging (fMRI).Ethics and dissemination This RCT obtained approval from independent ethics committees of participating centres and is accompanied by a data and safety monitoring board. …”
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Use of quantitative CT chest imaging to derive and assess a radiographic phenotype of deployment-related constrictive bronchiolitis by Alexander J. Bell, Maria Masotti, Sundaresh Ram, Gregory Pappas, Robert F. Miller, Ella A. Kazerooni, Charles R. Hatt, MeiLan K. Han, Bradley W. Richmond, Michael J. Falvo, Craig J. Galban, John J. Osterholzer

“…Differences in unadjusted QCT metrics and demographic variables between cohorts were identified and further assessed by principal component analysis. Thereafter, adjusted data from the DRCB cohort was used to derive a QCT-based radiographic phenotype of DRCB expressed as a DRCB-Probability Index (DRCB-PI). …”
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Discovery and preliminary validation of five early gastric cancer biomarkers, including TAGLN2 and CTSD, based on serum proteomics by DU Kewei, ZHANG Shangdi, HU Wenfei, GAO Shan, GAN Jianxin, YOU Chongge

“…A protein spectral library was established using Data-Dependent Acquisition (DDA) mode, and each sample was analyzed using Data-Independent Acquisition (DIA) mode. …”
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Character Education Values in the Sufism Book of Nuzhah al-Majalis wa Muntakhab an-Nafa’is: Enhancing the Akhlak Tasawuf Course to Foster Moderate Muslim Character at PTKIN by Zubaedi Zubaedi, Adi Saputra

“…The research design uses literature research (library study). Data collection techniques used by researchers include (1) Documentation studies; (2) Interviews; (3) Observation—data analysis using content analysis. …”
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CircEPDR1 regulates proliferation and differentiation of goat skeletal muscle satellite cells through miR-345-3p/Akirin1 axis by Song Shi, Diansong Duan, Jing Luo, Zihao Zhao, Tao Ma, Dinghui Dai, Siyuan Zhan, Jiaxue Cao, Jiazhong Guo, Tao Zhong, Linjie Wang, Hongping Zhang, Li Li

“…Mechanically, miR-345-3p directly targeted circEPDR1, and its function in myogenesis was completely reversed to that of circEPDR1. …”
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Efficacy and Safety of a Novel Low-Dose Water-Dispersible Turmeric Extract in the Management of Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial by Thanawala S, Shah R, Alluri KV, Bhupathiraju K, Prasad N, Agarwal Y

“…Study endpoints included assessment of changes from baseline to day 90 in pain intensity (visual analog scale [VAS], knee injury and osteoarthritis outcome score [KOOS]), inflammatory biomarkers, and safety profile. Data were analyzed using independent t-test, chi-square test, and analysis of co-variance test.Results: In total, 139 participants (WDTE60N, n = 70; placebo, n = 69) with mean age and BMI of 56.35 years and 23.89 kg/m2, respectively, were included. …”
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Improved mental health outcomes and normalised spontaneous EEG activity in veterans reporting a history of traumatic brain injuries following participation in a psilocybin retreat by Grace Blest-Hopley, Giuseppe Pasculli, Giuseppe Pasculli, Simon G. D. Ruffell, WaiFung Tsang, Olateju Emmanuel, Kathryn M. Pate, Hannes Kettner, Hannes Kettner, Leor Roseman, David Erritzoe, Robin Carhart-Harris, Robin Carhart-Harris

“…Paired t-tests were used to analyze changes in psychological scores, while EEG frequency band analysis assessed changes in brain function and connectivity.ResultsImprovements were observed across several mental health measures: PTSD (PCL-5 scores decreased by 50%, p=0.010), depression (PHQ-9 scores decreased by 65%, p<0.001), and anxiety (STAI) scores decreased by 28%, p<0.001). …”
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Fraca pressão aérea intraoral na fala após correção cirúrgica da fissura palatina The presence of low intraoral pressure in speech following surgical correction of cleft palate... by Daniela Aparecida Barbosa, Laura Davison Mangilli, Claudia Regina Furquim de Andrade, Nivaldo Alonso

“…Among the parameters evaluated, weak intraoral air pressure was an important variable considered in this study. RESULTS: Data analysis revealed a higher frequency of weak intraoral air pressure in the GT group (33%) as compared to the GP group (18%). …”
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To elucidate the neuroprotective effect of omega-3 fatty acid supplementation in acute spinal cord injury subjects: A prospective longitudinal cohort study by Khurshid Alam Ansari, Priyank Pratap, Zeenat Ara, Muhammad Shahid Raza, Sharad Verma, Shah Waliullah, Mohd Yoosuf

“…Conclusion: Omega-3 fatty acid, a neutraceutical, helps in facilitating neurological and functional recovery in acute SCI in comparison to subjects on conventional treatment.…”
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Web-based early intervention for children with motor difficulties aged 3–8 years old using multimodal rehabilitation (WECARE): protocol of a patient-centred pragmatic randomised tr... by Thomas G Poder, Desiree B Maltais, Tibor Schuster, Marie-Claude Battista, Michelle Phoenix, Jean-Patrice Baillargeon, Chantal Camden, Jill G Zwicker, Melanie Morin, Melanie Couture, Mathieu Goyette, Gabrielle Pratte, Karen Hurtubise, Tram Nguyen, Jade Berbari, Michel Tousignant

“…Families will have access to videoconferences with an assigned rehabilitation therapist using a collaborative coaching approach, a private chat function, a forum open to all intervention arm participants and online resources pertaining to child development. …”
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Hepatoprotective Therapy Efficacy in Obstructive Hepatobiliary Diseases: A Prospective Randomized Study by Mykhailo Maksymenko, Olexii Kulivets, Roman Havryliuk, Walery Zukow

“…An integrated therapeutic approach incorporating hepatoprotectors for obstructive hepatobiliary diseases enables more rapid restoration of hepatic functional status and potentially mitigates the risk of complications.  …”
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Bioinformatics and experimental insights into F2RL1 as a key biomarker in cervical cancer diagnosis and prognosis by Yonggang Dai, Chunxiang Li, Shiliang Cheng, Hongya Wang, Xuewei Zhuang

“…Immune-related genes were identified with F2RL1-related genes through ImmPort database analysis. Functional enrichment analysis was carried out using GO, KEGG, and GSEA. …”
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Analisis Status Keberlanjutan Sumber Mata Air Senjoyo pada Dimensi Ekologi dengan Metode RAP-WARES (Rapid Appraissal for Water Resources) by Anggia Agatha Reza, Desti Christian Cahyaningrum, Susanti Pudji Hastuti

“…The difference between the Monte Carlo Index and the MDS Index is 0.246, which proves that the error in the scoring process for each attribute, the variation in presenting scores for each attribute, and the results of the respondent's disagreement are relatively small. Also, the analysis process that is repeated is stable and errors in data entry and loss can be avoided. …”
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Airway complications after lung transplantation: Perioperative risk factors and clinical outcomes by Siddhartha G. Kapnadak, MD, Kathleen J. Ramos, MD, MS, Rachel Flodin, MS, Sanaa Mansoor, MD, Kyle Bilodeau, MD, Peter Beidler, BS, Erika D. Lease, MD, Ryan Thomas, BS, Richard Dubois, MD, Jay Pal, MD, PhD, Michael S. Mulligan, MD

“…Background: Airway complications after lung transplantation are common and contribute to worse outcomes. There are limited data documenting perioperative risk factors that could be mitigated to reduce risk. …”
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Cognition and experience of surgical incisions in patients undergoing laparoscopic surgery with enhanced recovery after surgery protocol: A qualitative study by Hongxia Xu, Yihong Xu, Gongjie Shi, Jiaqi Lu, Liping Zhu, Guibing He, Xiao Liang

“…Semi-structured interviews, covering physical function, social function, emotional function, self and others’ acceptance, and confidence in the nature and treatment of the disease, were audio-recorded and transcribed verbatim and guided by a thematic framework co-developed by surgeons, nurses, and psychologists. …”
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Advancements in Herpes Zoster Diagnosis, Treatment, and Management: Systematic Review of Artificial Intelligence Applications by Dasheng Wu, Na Liu, Rui Ma, Peilong Wu

“…AI applications were analyzed across three domains: (1) diagnosis, where mobile deep neural networks, convolutional neural network ensemble models, and mixed-scale attention-based models have improved diagnostic accuracy and efficiency; (2) treatment, where machine learning models, such as deep autoencoders combined with functional magnetic resonance imaging, electroencephalography, and clinical data, have enhanced treatment outcome predictions; and (3) management, where AI has facilitated case identification, epidemiological research, health care burden assessment, and risk factor exploration for postherpetic neuralgia and other complications. …”
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LIPUS promotes osteogenic differentiation of rat BMSCs and osseointegration of dental implants by regulating ITGA11 and focal adhesion pathway by Chao Liang, Yuqing Zhang, Yuwei Yan, Wei Geng, Jun Li, Xiu Liu

“…Results Our in vivo experimentations verified that LIPUS significantly increased new bone formation and osseointegration around the implant in rats. Bioinformatics analysis of RNA-seq data revealed that the upregulated genes in BMSCs after LIPUS treatment were significantly enriched in osteoblast differentiation-related functions and focal adhesion-related pathways. …”
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Identification of a novel subtype of SPP1 + macrophages expressing SIRPα: implications for tumor immune evasion and treatment response prediction by Kun Chen, Yida Li, Jianjiao Ni, Xi Yang, Yue Zhou, Yechun Pang, Ruiting Ye, Hongru Chen, Silai Yu, Peng Wang, Zhengfei Zhu

“…Kaplan–Meier method was used for survival analysis. In vitro and in vivo studies investigating the function of SPP1 + macrophages were performed. …”
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Nosing beyond the stone age: deciphering nasal evolution from Neanderthals to modern Man by Francisco Alves de Sousa, Joana Ida Dias, Rita Teixeira Carvalho, Clara Serdoura Alves, Ana Nóbrega Pinto, Mariline Santos, Luís Meireles

“…Objectives: This study explores these differences through a comparative analysis of cranionasal measurements. Material and Methods: Data on Neanderthal nasal features were obtained from existing paleoanthropological literature, focusing on 16 hominid fossils. …”
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Euthanasia and Physician-assisted Suicide in Patients with Amyotrophic Lateral Sclerosis (Review of the Literature and Description of a Clinical Case) by Nehrych T., Papish M., Shorobura M.

“…As the disease doesn’t usually affect cognitive abilities, the patients are aware of the progressive loss of function and may become irritable and fall into depression. …”
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