Cerebellar Information Processing in Relapsing-Remitting Multiple Sclerosis (RRMS) by E. Lesage, M. A. J. Apps, A. L. Hayter, C. F. Beckmann, D. Barnes, D. W. Langdon, N. Ramnani

“…This enabled us to localize differences between conditions that change as a function of group (group-by-condition interactions). …”
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Theoretical fundamentals of mechanochemical reactions in the solid phase by Đorđević Nataša, Mihajlović Slavica, Vlahović Milica, Kašić Vladan, Matijašević Srđan, Grubišić Mirko

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Causal role of immune cells in head and neck squamous cell carcinoma by Panshu Xu, Zhenxing Zhang, Haoran Zhu, Conglin Hu, Yukang Ying

“…Based on the summary-level data from a genome-wide association study (GWAS), this study used Mendelian randomization (MR) analysis to investigate the causal relationship between immune cell phenotype and HNSCC. …”
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Utilizing bioinformatics and machine learning to identify CXCR4 gene-related therapeutic targets in diabetic foot ulcers by Hengyan Zhang, Ye Zhou, Heguo Yan, Changxing Huang, Licong Yang, Yangwen Liu

“…Functional enrichment analysis showed that these genes were mainly involved in pathways such as oxidative phosphorylation, phagosome, synaptic vesicle cycle, and pathways of neurodegeneration. …”
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CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β-catenin signaling pathway by Zicheng Wei, Kezhou Xia, Wenda Liu, Xinghan Huang, Zhun Wei, Weichun Guo

“…The downstream pathway of CGREF1 was identified through RNA sequencing analysis. Cell counting kit-8 (CCK-8) assay, colony formation assay, flow cytometry, wound healing assay, and Transwell assay were conducted for in vitro functional experiments. …”
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Identifying and Diagnosing Lytic Cell Death Genes in Atherosclerosis Using Machine Learning and Bioinformatics by Zhang G, Ma R, Jin H, Zhang Q, Li W, Ding Y

“…Two subtypes, C1 (non-immune subtype) and C2 (immune subtype), were delineated based on immune landscape analysis and gene set variation analysis functional enrichment. …”
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Development and Validation of an Anoikis-Related Gene Signature for Prognostic Prediction in Cervical Cancer by Meng S, Li X, Zhang J, Cheng X

“…Furthermore, we compared the biological processes and pathway enrichment in high-risk and low-risk patient groups, using differential gene expression and functional enrichment analysis. Finally, we investigated the immune microenvironment of patients in both high-risk and low-risk groups.Results: Patients in the high-risk group had significantly poorer survival compared to those in the low-risk group. …”
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Implementation of Business Process Mapping Framework for Indonesia’s Government Institutions by Martinus Tukiran, Nugraheni Puspita Sari, Lukas Danny Tjitrabudi, Nurul Amalia

“…The research employed a qualitative approach with in-depth interviews, observation, and study documents were performed for collecting and analysis data.  The framework was succeeding to describe a paradigm shifting to encourage people move from a silo thinking to cross function team. …”
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Time-Varying Uncertainty in Shock and Vibration Applications Using the Impulse Response by J.B. Weathers, Rogelio Luck

“…The uncertainty analysis procedure for these kinds of time-varying problems can be challenging, and in many instances, explicit data reduction equations (DRE's), i.e., analytical formulas, are not available because the outputs of interest are obtained from complex simulation software, e.g. …”
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Tenant mix structure in shopping centres: some empirical analyses from Poland by Bartłomiej Marona, Anna Wilk

“…The Analytic Hierarchy Process was applied in the analysis of the data collected. Findings: The research confirmed that to a great extent the valid tenant mix structure in the surveyed shopping centres meets with friendly attitude of customers. …”
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Exploring Factors Affecting People’s Acceptance of Connected Vehicle Technology in China by Lingyu Zheng, Yuntao Guo, Yajie Zou

“…Connected vehicles (CVs) leverage the vehicle-to-everything (V2X) function to interact with various mobility systems. …”
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Acetylation of the yeast Hsp40 chaperone protein Ydj1 fine-tunes proteostasis and translational fidelity. by Siddhi Omkar, Megan M Mitchem, Joel R Hoskins, Courtney Shrader, Jake T Kline, Nitika, Luca Fornelli, Sue Wickner, Andrew W Truman

“…By mutating acetylation sites on Ydj1's J-domain to either abolish or mimic constitutive acetylation, we observed that preventing acetylation had no noticeable phenotypic impact, whereas acetyl-mimic mutants exhibited various defects indicative of impaired Ydj1 function. Proteomic analysis revealed several Ydj1 interactions affected by J-domain acetylation, notably with proteins involved in translation. …”
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Exploring the impact of PFAS exposure and sleep duration on kidney stone formation in the U.S. population by Jianbai Chen, Zhiming Zhang, Gongquan Xu, Qisheng Tang, Zhiyong Nie, Jianxin Qiu, Xiaoping Gao

“…Concurrently, sleep duration has been implicated in metabolic dysregulation, influencing kidney function. While individual studies have examined the effects of PFAS exposure and sleep duration on kidney health, their combined impact on kidney stone formation remains largely unexplored.MethodsWe conducted a cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) 2013-2016. …”
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Sulforaphane from Brassica Oleracea Induces Apoptosis in Oral Squamous Carcinoma Cells via p53 Activation and Mitochondrial Membrane Potential Dysfunction by Pooja Narain Adtani, Sura Ali Ahmed Fuoad Al-Bayati, Walid Shaaban Elsayed

“…<b>Conclusions:</b> The data obtained indicate that SFN has significant potential to induce apoptosis in OECM-1 cells by disrupting mitochondrial function and modulating apoptotic pathways. …”
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Insurance policy and cropping structure adjustment toward staple grains in China: implications for food system resilience and security by Jiawei Wang, Jiawei Wang, Zihui Yuan, Zhihua Wu, Xia Kuang, Feng Ye

“…However, empirical evidence on this guiding function remains limited.MethodsDrawing on data from the 2020 China Rural Revitalization Survey (CRRS), this study employs a two-limit Tobit model to examine the impact pathways and moderating mechanisms through which agricultural insurance affects farmers’ cropping structure adjustment. …”
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About the role of intestinal microbiota in the pathogenesis and treatment of non-alcoholic fatty liver disease by D. M. Khalilova, G. M. Sahautdinova

“…A large number of works has demonstrated without any doubt the connection between non-alcoholic fatty liver disease, small intestine bacterial overgrowth, and increased endotoxemia, it supports the hypothesis that patients with non-alcoholic fatty liver disease have weakening of intestinal barrier function and the formation of "leaky gut". Based on literature data, the need to complete non-alcoholic fatty liver disease therapy in order to stabilize the permeability of the intestinal epithelium and to increase the pool of butyrate-producing bacteria with butyrate preparations that can be introduced into the human body exogenously.Conclusion. …”
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Assessing thyroid health: phenotypic age compared to chronological age by Dongyu Yang, Cihang Lu, Haonan Zhang, Xiaoguang Shi, Ying Sun, Ying Shao, Shuting Fan, Lijun Tian, Di Teng

“…IntroductionAging is associated with thyroid dysfunction, but the role of phenotypic age, a biological aging measure derived from nine clinical biomarkers and chronological age, remains unclear.MethodsThis cross-sectional study included 6,681 adults from the National Health and Nutrition Examination Survey (NHANES, 2007–2012) with complete thyroid function and age data. Participants were grouped into quartiles based on chronological and phenotypic age. …”
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A Hybrid RBF-PSO Framework for Real-Time Temperature Field Prediction and Hydration Heat Parameter Inversion in Mass Concrete Structures by Shi Zheng, Lifen Lin, Wufeng Mao, Yanhong Wang, Jinsong Liu, Yili Yuan

“…Three objective functions—integral-type (<i>F</i>₁), feature-driven (<i>F</i>₂), and hybrid (<i>F</i>₃)—were systematically compared using experimental data from a C40 concrete specimen under controlled curing. …”
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Unraveling the Heterogeneity of CD8+ T-Cell Subsets in Liver Cirrhosis: Implications for Disease Progression by Kepu Zheng, Leiyang Dai, Shengning Zhang, Yingpeng Zhao, Wang Li, Yang Gao, Yuanyi Mang, Lingfeng Jiao, Yu Tang, Jianghua Ran

“…CXCL13+ Tex cells displayed T-cell exhaustion markers like PDCD1, HAVCR2, TIGIT, and TNFRSF9. Functional analysis implicated potential roles of these cells in immunosuppression. …”
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Modulation of senescent Lepr+ skeletal stem cells via suppression of leptin-induced STAT3‒FGF7 axis activation alleviates abnormal subchondral bone remodeling and osteoarthritis pr... by Fu-Hao Yu, Bo-Feng Yin, Ming-Yu Liu, Wen-Jing Zhang, Zhi-Dong Zhao, Lei Wang, Xiao-Tong Li, Pei-Lin Li, Zhi-Ling Li, Run-Xiang Xu, Li Ding, Heng Zhu

“…The one-way ANOVA was used in multiple group data analysis. Results scRNA-seq and pathological data demonstrated that the leptin receptors (Lepr) positive SSCs underwent cellular senescence during OA progression. …”
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