Implication of CCNG1 in radiosensitivity via the Wnt/β-catenin pathway in esophageal squamous cells by Yuxiang Zhang, Zhiman Zhu, Naihan Ren, Dongni Wang, Xue Zeng, Na Zhang

“…In radioresistant ESCC cell lines, CCNG1 knockdown markedly increased radiosensitivity, as demonstrated by enhanced G2/M phase arrest and apoptosis following radiation exposure. CellChat analysis indicated a correlation between CCNG1 and the Wnt/β-catenin signaling pathway, while western blot (WB) analysis confirmed that CCNG1 functions as a downstream effector of Wnt/β-catenin. …”
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Kinematic Parameters for Tracking Patient Progress during Upper Limb Robot-Assisted Rehabilitation: An Observational Study on Subacute Stroke Subjects by Michela Goffredo, Stefano Mazzoleni, Annalisa Gison, Francesco Infarinato, Sanaz Pournajaf, Daniele Galafate, Maurizio Agosti, Federico Posteraro, Marco Franceschini

“…The Wilcoxon signed-rank tests were used with clinical outcomes. the Friedman test and post hoc Conover’s test (Bonferroni’s correction) were applied to KPs. A secondary data analysis has been conducted by comparing patients having different severities of motor impairment. …”
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The Effects of Gas Humidification with High-Flow Nasal Cannula on Cultured Human Airway Epithelial Cells by Aaron Chidekel, Yan Zhu, Jordan Wang, John J. Mosko, Elena Rodriguez, Thomas H. Shaffer

“…These data demonstrate that exposure to low humidity results in reduced epithelial cell function and increased inflammation.…”
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An atlas of immune cell exhaustion in HIV-infected individuals revealed by single-cell transcriptomics by Shaobo Wang, Qiong Zhang, Hui Hui, Kriti Agrawal, Maile Ann Young Karris, Tariq M. Rana

“…These data provide a comprehensive analysis of gene signatures associated with immune cell exhaustion during HIV infection, which could be useful in understanding exhaustion mechanisms and developing new cure therapies.…”
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Impact of vitamin A on aged people’s cognition and Alzheimer’s disease progression in an animal model by Pengfei Li, Jingjing Xu, Yujie Guo, Xiaojun Ma, Xixiang Wang, Lu Liu, Yu Liu, Xiuwen Ren, Jiahao Li, Ying Wang, Liping Meng, Shaobo Zhou, Linhong Yuan

“…Population-based cross-sectional and animal diet intervention studies were conducted to analyze the association between VA nutritional status and cognitive function and the underlying mechanisms. In the population-based study, information from 1817 adults aged 50 years and above was used for data analysis, and we found that subjects with plasma VA level greater than 0.539 μg/ml displayed a lower risk of mild cognitive impairment (MCI). …”
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Development and reliability and validity testing of a medication literacy scale for medical college students by Zeng Leixiao, Sun Xiaonan, Pan Lutong, Gu Wenjing, Xiao Chang, Tang Jingqi, Dai Wenting, Kang Xiuqin, Wu Yibo

“…The item-level content validity index (I-CVI) ranged from 0.833 to 1.000 (≥ 0.78). Factor analysis of 14 items showed that KMO = 0. 852(> 0.7) and Bartlett’s spherical test p < 0.001, indicating that the data are very suitable for factor analysis. …”
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High expression of SOX9 is a diagnostic and prognostic indicator of glioma by Libo Xu, Zhenhao Wang, Mao Li, Qingsong Li

“…Moreover, functional enrichment analysis of GBM-related DEGs was performed by GO/KEGG, GSEA, and protein-protein interaction (PPI) network. …”
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Elimination of cetyldimethylethylammonium ammonium bromide from water by almond shell based magnetic activated carbon/membrane hybrid processes by Muhammad Zahoor, Sultan Alam, Muhammad Ali, Azmat Ullah, Adnan Khan, Sana Ben Moussa, Abdullah Yahya Abdullah Alzahrani

“…The BET surface area was 74.99 m2 g−1 and the BJH pore size distribution was 61.08 m2 g−1, total pore volume of 0.073 cm3 g−1 and a pore diameter of 15.55 Å. The FTIR analysis of AMCNC identified surface functional groups like carboxylic acid, phenols, and ethereal groups along with a band at 580 cm−1, corresponds to FeO linkage. …”
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Genome‐wide screening of abberant methylated drivers combined with relative risk loci in bladder cancer by Chuanjie Zhang, Kangjie Shen, Yuxiao Zheng, Feng Qi, Jun Luo

“…Methods We utilized TCGA‐Assembler package to download 450K methylation data and corresponding transcriptome profiles. MethylMix package was used for identifying methylation‐driven genes and functional analysis was mainly performed based on ConsensusPathDB database. …”
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Enhancing cardiovascular monitoring: a non-linear model for characterizing RR interval fluctuations in exercise and recovery by Matías Castillo-Aguilar, Diego Mabe-Castro, David Medina, Cristian Núñez-Espinosa

“…Abstract This work aimed to develop and validate a novel non-linear model to characterize RR interval (RRi) time-dependent fluctuations throughout a rest-exercise-recovery protocol, offering a more precise and physiologically relevant representation of cardiac autonomic responses than traditional HRV metrics or linear approaches. Using data from a cohort of 272 elderly participants, the model employs logistic functions to capture the non-stationary and transient nature of RRi time-dependent fluctuations, with parameter estimation achieved via Hamiltonian Monte Carlo. …”
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Morphology of exorbital lacrimal glands of not purebred white rats at high-intensity light influence by L. R. Mustafina, A. D. Zhuravleva, S. V. Logvinov, M. R. Karpova, T. V. Lasukova, G. A. Sukhanova, N. N. Ilinskich

“…By means of an oculary insert of Avtandilov counted specific volumes of output channels, an epithelium, stroma and vessels of exorbital lacrimal glands, defined an epitelio/stroma ratio. The analysis of data was carried out by methods of descriptive statistics with calculation of a median (Ме) and interquartile range (Q1 –Q3). …”
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T-cell receptor variable region usage in Chagas disease: A systematic review of experimental and human studies. by Thaiany Goulart de Souza-Silva, Kenneth J Gollob, Walderez O Dutra

“…It was also demonstrated that murine Vβ9+ T cells derived from nonlymphoid organs of T. cruzi-infected animals had a modulatory profile, while splenic Vβ9+ T cells produced inflammatory cytokines, indicating that although they display the same TCR Vβ region usage, these cells are functionally distinct. Despite the limitations of few papers and year of publication of the studies, compiling the data derived from them reveals that further investigation of TCR usage will point to their potential role in protective or pathogenic responses, as biomarkers of disease progression, and in the search for dominant peptides potentially useful for the development of vaccines or therapies.…”
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Simulation of Quantity and Quality of Saq Aquifer Using Artificial Intelligence and Hydraulic Models by Abdul Razzaq Ghumman, Ghufran Ahmed Pasha, Md. Shafiquzzaman, Afaq Ahmad, Afzal Ahmed, Riaz Akhtar Khan, Rashid Farooq

“…Five types of ANN models with various training functions have been investigated to find the most efficient training function for the prediction of quantity and quality of groundwater, which is an original contribution useful for engineering sector. …”
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Surface quality prediction and validation of Electro-Fenton chemical mechanical polishing for single crystal SiC based on neural network models by Jiacheng Geng, Jiayun Deng, Zilei Bai, Xiaoning Wen, Jiabin Lu, Qiusheng Yan, Xiaojing Yang

“…Predictive models are developed using Radial Basis Function (RBF), Back Propagation (BP), and Convolutional Neural Networks (CNN) to explore the relationships between process parameters, MRR, and surface roughness Ra. …”
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Linking preclinical models to clinical realities: VEGF/VEGFR inhibitors and thrombotic microangiopathy in cancer therapy by Aimin Jiang, Zhanzhi Li, Ying Liu, Junyi Shen, Quan Cheng, Anqi Lin, Peng Luo, Linhui Wang

“…We also examined TMA and thrombotic thrombocytopenic purpura (TTP) risks using patient biochemical data from a local hospital and explored underlying biological mechanisms through animal models and pan‐cancer analysis. …”
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Non-linear matter power spectrum modeling in interacting dark energy cosmologies by Emanuelly Silva, Ubaldo Zúñiga-Bolaño, Rafael C. Nunes, Eleonora Di Valentino

“…In this work, we present an analysis of the non-linear matter power spectrum within the framework of interacting dark energy-dark matter cosmologies (IDE). …”
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Characterization of adverse reactions to four common targeted drugs for hepatocellular carcinoma in WHO-VigiAccess by Zeyu Wang, Jiyao Sheng, Xuewen Zhang

“…The analysis included demographic data such as patient age, gender, and geographical distribution, alongside clinical information on the systems and symptoms associated with ADR reports. …”
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Strengthening Farmer Institutions in Rice Farming: An Interpretive Structural Modeling Approach by Sri Wahyuni Kamaruddin, Zulkifli Zulkifli, Akbar Akbar

“…Purposive sampling was utilized to choose 21 farmers and 5 stakeholders from a population of 150 farmers, resulting in a sample size of 26 persons. The data analysis technique utilized was a Likert scale using ISM. …”
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Crucial role of TRPC1 and TRPC4 in cystitis-induced neuronal sprouting and bladder overactivity. by Mathieu Boudes, Pieter Uvin, Silvia Pinto, Marc Freichel, Lutz Birnbaumer, Thomas Voets, Dirk De Ridder, Rudi Vennekens

“…To assess bladder function and referred hyperalgesia, urodynamic analysis, detrusor strip contractility and Von Frey filament experiments were done in wild type and knock-out mice.…”
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The AUKUS Treaty and Australian Deterrence: Changing Dynamics in the Indo-Pacific by Fatemeh Mahroogh, mohammad karampouriy

“…The research findings show that the AUKUS agreement, by creating synergy between various military and non-military domains, will disrupt the regional order in the region from a "geography of peace" to a "geography of conflict" and cause function of order on the edge of chaos. The article is using the content analysis method of qualitative data collected from reports, national defense documents, updated defense strategic documents 2020 and Australia's maritime security strategy 2022, comments of Australian government officials, the analysis of experts and experts in East Asian defense issues and security study centers have been used.…”
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