The phosphoproteome of toll‐like receptor‐activated macrophages by Gabriele Weintz, Jesper V Olsen, Katja Frühauf, Magdalena Niedzielska, Ido Amit, Jonathan Jantsch, Jörg Mages, Cornelie Frech, Lars Dölken, Matthias Mann, Roland Lang

“…Finally, weaving together phosphoproteome and nascent transcriptome data by in silico promoter analysis, we implicated several phosphorylated TFs in primary LPS‐controlled gene expression.…”
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How to assess water quality change in temperate headwater catchments of western Europe under climate change: examples and perspectives by Gascuel-Odoux, Chantal, Fovet, Ophélie, Faucheux, Mikaël, Salmon-Monviola, Jordy, Strohmenger, Laurent

“…From these examples, we highlight four challenges for research on the relationships between climate and water quality: (i) developing functional typologies of chemical elements, (ii) performing multi-temporal and multi-spatial analysis by aggregating data into water-cycle periods, (iii) decoupling effects of climate conditions and human activities by testing hypotheses using parsimonious models, and (iv) incorporating water quality and aquatic ecosystem health into integrated models. …”
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Exploring the Time to Onset and Early Predictors of Poststroke Spasticity Combined With Surface Electromyography: Protocol for a Nested Case-Control Study by Simeng Song, Shiliang Wang, Shanshan Zeng, Wenqing Wu, Lingying Wu, Xukun Tang, Xiongxing Sun, Dahua Wu, Le Xie

“…Data processing, analysis, and visualization were conducted using Statistical Package for the Social Sciences software (version 26.0; IBM Corp). …”
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Integrated machine learning and single-cell RNA sequencing reveal COL4A2 and CXCL6 as oxidative stress-associated biomarkers in periodontitis by Siyu Sun, Siyu Sun, Jing Ren, Jing Ren, Xiujuan Zeng, Yanbin Chen, Qianbing Zhou, Junying Yang, Shan Chen

“…Key genes linked to oxidative stress in periodontitis were identified through a comprehensive analytical approach, including differential expression analysis, weighted gene co-expression network analysis (WGCNA), gene set enrichment analysis (GSEA), and functional enrichment analyses (GO and KEGG). …”
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Maternal Clostridium butyricum supplementation during late gestation and lactation enhances gut bacterial communities, milk quality, and reduces piglet diarrhea by Morakot Nuntapaitoon, Piraya Chatthanathon, Matanee Palasuk, Alisa Wilantho, Jakavat Ruampatana, Sissades Tongsima, Sarn Settachaimongkon, Naraporn Somboonna

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Disulfidptosis ‒ related lncRNAs are biomarkers of prognosis and immune response in Head and Neck Squamous Cell Carcinoma by Ruilin Wang, Qi Zhang, Yuxiu Ma, Xuelin Liu, Tian Lan, Hongling Li

“…In addition to functional enrichment analysis, the associations between the model and Tumor Mutation Burden (TMB), immune cell infiltration, and drug sensitivity were also examined. …”
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Telomere-related gene risk model predicts prognostic and immune microenvironment alterations in prostate cancer by Danfeng Zhao, Zhenjie Zang, Haodong Li, Ruiyu Li, Guanbo Wang, Keqin Zhang, Tongxiang Diao, Qiang Fu

“…Additionally, two hub genes were utilized to create risk models, with ROC curves confirming their predictive efficacy for 3-, 5-, and 10-year survival rates in patients. Functional analysis of these genes was conducted, and NPY siRNA transfection notably inhibited proliferation in LNCaP and DU145 cells. …”
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Declawing in Cat is associated with neuroplastic sensitization and long-term painful afflictions by Mathieu LaChance, Colombe Otis, Tristan Juette, Jérôme R. E. del Castillo, Aliénor Delsart, Maxim Moreau, Beatriz P. Monteiro, Aude Castel, Bertrand Lussier, Johanne Martel-Pelletier, Jean-Pierre Pelletier, Eric Troncy

“…Here, the aim was to distinguish chronic post-declaw pain from OA-related pain. A secondary analysis of eight studies on feline OA was conducted, comparing somatosensory, biomechanical and functional assessments between healthy control cats, declawed OA (DOA) cats, and non-declawed OA (NDOA) cats. …”
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The strategic alliance of higher education institutions: Experience of contemporary Germany by A. M. Petrov

“…The methodological framework involves the following general scientific methods: systematisation and generalisation, structural and functional analysis, comparative and retrospective analysis of data from international rankings. …”
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Comorbidities of Obesity in a Rural African Population Residing in Limpopo Province, South Africa: A Comparison between General and Central Obesity by Cairo B. Ntimana, Reneilwe G. Mashaba, Kagiso P. Seakamela, Eric Maimela, Matshane L. Masemola-Maphutha, Solomon S. R. Choma

“…Centrally obese participants were more likely to be diabetic, hypertensive, have dyslipidaemia, and exhibit reduced kidney function.…”
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Photodynamics of clusters of the major components of the atmosphere by V. Aquilanti, M. Bartolomei, D. Cappelletti, E. Carmona-Novillo, F. Pirani

“…Accurate intermolecular potential energy surfaces for the major components of the atmosphere, leading to the characterization of the O2-O2, N2-N2 and N2-O2 dimers, have been obtained from the analysis of scattering experiments from our laboratory, also exploiting where available second virial coefficient data. …”
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Quantification of human angiogenesis in immunodeficient mice using a photon counting-based method by Zhihong Dong, Kathleen G. Neiva, Taocong Jin, Zhaocheng Zhang, Daniel E. Hall, David J. Mooney, Peter J. Polverini, Jacques E. Nör

“…Most methods used for analysis of antiangiogenic drugs in vivo utilized histologic examination of tissue specimens, which often requires large sample sizes to obtain reliable quantitative data. …”
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Physicians’ experiences of assessing and supporting fatigued patients in primary care: a focus group study by Conrad Samuelsson, Lisa Gunnarsson, Frank Svärdman, Christian Rück, Elin Lindsäter

“…Method Six semi-structured focus group interviews were conducted, including a total of 39 primary care physicians from three primary care centres in Stockholm. Data was analysed using thematic analysis. Results The analysis generated the overarching theme "Frustration in the role as physician," consisting of two main themes: (1) “Time pressure and an empty toolbox”, highlighting the perceived lack of standardised assessment procedures, effective interventions, and sufficient time for care; and (2) “Challenges in the patient-physician relationship”, highlighting role ambivalence, ambivalence regarding sick leave, and the importance of reaching mutual understanding with the patient. …”
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Exploring Autophagy-Related Gene Expression in Hepatocellular Carcinoma via TCGA, GEPIA2, and HPA Databases: Implications for Prognosis by Gu X, Chen Y, Hu X, Li Y, Zhu R, Li H, Yuan Z, Wang Y

“…Differential expression analysis between normal and tumor tissues relied on data from The Cancer Genome Atlas (TCGA). …”
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Retinal photoreceptor ellipsoid zone is a structural biomarker for visual outcome after successful macular hole surgery: A novel grading system-based study by Samya Singh, Sandeep Saxena, Carsten H Meyer, Aman Chandra, Levent Akduman

“…Spectral domain optical coherence tomography (SD-OCT) cross-sectional analysis was performed on preoperative and postoperative data of weeks 1, 4, 12, and 24, respectively. …”
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NSA-CHG: An Intelligent Prediction Framework for Real-Time TBM Parameter Optimization in Complex Geological Conditions by Youliang Chen, Wencan Guan, Rafig Azzam, Siyu Chen

“…Validation experiments employing field data from the Pujiang Town Plot 125-2 Tunnel Project demonstrated superior performance metrics, including 92.4% ± 1.8% warning accuracy for fractured zones, ≤28 ms optimization response time, and ≤4.7% relative error in energy dissipation analysis. …”
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Resilient healthcare theory as a lens to research emergency department operations: a protocol for a scoping review by Janet E Anderson, Mark Sujan, Andreas Xyrichis, Peter Thomas Chessum

“…A two-stage approach will be undertaken to synthesise and report results: (1) numerical analysis of the nature and distribution of studies (the overall number of studies, country of origin, the most studied core function of ED, type of research design); and (2) a thematic mapping of the literature.Ethics and dissemination Scoping review methodology synthesises published data and, therefore, does not require ethical approval. …”
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Optimization of Table Tennis Swing Action Supported by the Temporal Convolutional Network Algorithm in Deep Learning by Shaoxuan Sun, Hongyu Zheng, Zhixin Lin

“…The research effectively addresses the vanishing gradient problem by replacing the traditional Rectified Linear Unit (ReLU) activation function with Leaky ReLU, while simplifying the network structure through the use of a Global Average Pooling layer to reduce model complexity. …”
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Pemberian Dolomit Pada Kultur Daphnia spp. Sistem Daily Feeding Pada Populasi Daphnia spp. dan Kestabilan Kualitas Air <Br><I>[Dolomite Added At Culture Of Daphnia spp. Daily Fee... by A. Shofy Mubarak, Laksmi Sulmartiwi, Diah Trie Ridyaning Tias

“…Parameter that measured were Daphnia spp. population and water quality, such as temperature, pH, ammonia, dissolve oxygen and alkalinity. The data were examined using ANAVA(Analysis of Variance) to know treatment effect and be continued by Duncan Multiple Range with trust of degree 0,05. for water stability using descriptif methode. …”
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Solution structure and phylogenetics of Prod1, a member of the three-finger protein superfamily implicated in salamander limb regeneration. by Acely Garza-Garcia, Richard Harris, Diego Esposito, Phillip B Gates, Paul C Driscoll

“…<h4>Methodology/principal findings</h4>With the aim of identifying potential orthologs of Prod1, we have solved its 3D structure and compared it to other known TFPs using phylogenetic techniques. The analysis shows that TFP 3D structures group in different categories according to function. …”
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