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12521
Construction of a 12-gene prognostic model for colorectal cancer based on heat shock protein-related genes
Published 2024-12-01“…Single sample gene set enrichment analysis (ssGSEA) further revealed differences in immune cell types and immune functional status between the two risk groups. …”
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12522
Exploring unsupervised feature extraction algorithms: tackling high dimensionality in small datasets
Published 2025-07-01“…To overview this critical issue, this review focuses on unsupervised feature extraction algorithms (UFEAs) due to their ability to handle high-dimensional data without relying on labelled information. From this review, eight representative UFEAs were selected: principal component analysis, classical multidimensional scaling, Kernel PCA, isometric mapping, locally linear embedding, Laplacian Eigenmaps, independent component analysis and Autoencoders. …”
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12523
Biomarkers associated with cell-in-cell structure in kidney renal clear cell carcinoma based on transcriptome sequencing
Published 2025-04-01“…For single-cell data, the Seurat package is used to read the sample data, and the SCTransform function is employed for normalization. …”
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12524
Establishment of an evaluation system for conversion to laparotomy in laparoscopic cholecystectomy and exploration of surgical grading management
Published 2025-01-01“…Methods A retrospective analysis was conducted on the clinical data of 9 414 patients who underwent LC at Renhe Hospital and Huashan Hospital from June 2013 to June 2018. …”
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12525
De Novo Transcriptome Assembly of <i>Anoectochilus roxburghii</i> for Morphological Diversity Assessment and Potential Marker Development
Published 2024-11-01“…Multiple databases were used to obtain a comprehensive annotation, and the unigenes were functionally categorized using the GO (Gene Ontology), KOG (Eukaryotic Orthologous Groups), KEGG (Kyoto Encyclopedia of Genes and Genomes), and Nr databases. …”
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12526
Cultural nuances in subtitling the religious discourse marker wallah in Jordanian drama into English
Published 2025-03-01“…Two works, the series Jinn (2019) and the film Theeb (2014), are chosen as the corpus of the data. The study analyses the pragmatic functions of the religious marker wallah, which Arabs usually use to swear to God in different contexts and examines its English subtitles. …”
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12527
Medical marketing in healthcare institutions with public-private partnership mechanisms
Published 2023-06-01“…The study used general scientific methods of analysis, synthesis, generalization, interpretation of scientific data, as well as systemic and structural-functional approaches. …”
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12528
Some Peculiarities of the Use of Perfect Tense Forms in the Narration of the Holy Martyrs Boris and Gleb
Published 2016-10-01“…The paper deals with some results of the analysis of the perfect tense forms functioning in the copies of the Narration of the Holy Martyrs Boris and Gleb created in the 12th – 15th centuries. …”
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12529
Genome-wide identification and characterization of cation-proton antiporter (CPA) gene family in rice (Oryza sativa L.) and their expression profiles in response to phytohormones.
Published 2025-01-01“…Protein-protein interaction analysis suggested maximum functional similarities between rice and Arabidopsis CPA proteins. …”
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12530
Neural decoding of Aristotle tactile illusion using deep learning-based fMRI classification
Published 2025-06-01“…This study aimed to identify brain regions involved in the Aristotle illusion using functional magnetic resonance imaging (fMRI) and deep learning-based analysis of fMRI data.MethodsWhile three types of tactile stimuli (Aristotle, Reverse, Asynchronous) were applied to thirty participants’ fingers, we collected fMRI data, and recorded the number of stimuli each participant perceived. …”
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12531
Identification of novel candidate loci for Alzheimer’s disease and related dementias by leveraging the shared genetic basis with hippocampal volume
Published 2025-01-01“…To identify shared genetic risk loci across late-onset ADRD and bilateral hippocampal volumes, we conducted a cross-trait analysis of existing GWAS data on the two traits using the conjunctional false discovery rate (conjFDR) framework. …”
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12532
Identification of neutrophil extracellular trap-related biomarkers in ulcerative colitis based on bioinformatics and machine learning
Published 2025-06-01“…Enrichment analysis showed that these genes primarily mediate UC-related damage through biological functions such as leukocyte activation, migration, immune receptor activity, and the IL-17 signaling pathway. …”
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12533
Abstract 235: General Anesthesia vs. Non‐General Anesthesia in Endovascular Treatment for Patients with Acute Ischemic Stroke
Published 2023-11-01“…Results Eight RCTs were included in the final analysis (n=1203) with seven of them reporting data for the anterior circulation (n=1116) and one for the posterior circulation (n=87). …”
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12534
Shikonin as a therapeutic agent in renal cell carcinoma: insights from TEK-related causal association with glaucoma
Published 2025-07-01“…This study aimed to investigate the causal link between glaucoma and RCC and explore molecular intersections to identify novel therapeutic targets.MethodsA two-step Mendelian randomization (MR) analysis using genetic data from the NHGRI-EBI GWAS Catalog and FinnGen database was performed, supplemented by NHANES data. …”
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12535
Factors associated with head circumference and indices of cognitive development in early childhood
Published 2020-10-01“…To disentangle the associations between risk factors and HC from linear growth and to distinguish the direct and indirect effects of these risk factors on cognitive function, we conducted mediation analysis using longitudinal models to account for all data measured during follow-up.Results Average HC-for-age Z-score (HCAZ) was −0.54 (95% CI −0.47 to −0.62) near birth and −1.01 (95% CI −0.94 to −1.08) at 24 months. …”
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12536
The association between eight complete blood count-derived inflammatory markers and muscle health
Published 2025-02-01“…Receiver operating characteristic (ROC) curves were used to compare the predictive abilities of the different indices for low muscle mass and muscle strength. Additionally, NHANES data were cross-validated with data from 554 patients at our hospital to evaluate the ability of the systemic immune inflammatory index (SII) to distinguish between low muscle mass and strength.ResultsAfter controlling for all potential confounding factors, multiple logistic regression analysis revealed that apart from the platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), and derived NLR (dNLR), the neutrophil-to-monocyte-plus-lymphocyte ratio (NMLR), neutrophil-to-lymphocyte ratio (NLR), SII, systemic inflammation response index (SIRI), and pan-immune-inflammation value (PIV) were significantly negatively correlated with muscle mass and strength. …”
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12537
Client characteristics and outcomes of the Australian short-term restorative care programme: a cohort study
Published 2025-04-01“…The primary aim of this study was to provide a descriptive analysis of STRC participant and outcome data from clients’ first STRC episode with a large, aged care provider in New South Wales (NSW), Australia. …”
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12538
Effect of music listening on delirium after hip fracture operations (MLDHFO) in a regional hospital in Taiwan: a randomised controlled trial protocol
Published 2025-08-01“…Delirium has resulted in poorer functional recovery, increased readmission rates, repeat surgeries and elevated mortality. …”
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12539
Synergistic Network Pharmacology for Traditional Chinese Medicine Liangxue Tongyu Formula in Acute Intracerebral Hemorrhagic Stroke
Published 2021-01-01“…The RNA-seq data of the AICH-rats were analyzed for differential expression and functional enrichments. …”
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12540
CryoEM structure and small-angle X-ray scattering analyses of porcine retinol-binding protein 3
Published 2025-01-01“…In this study, we present a 3.67 Å cryoEM structure of porcine RBP3, along with molecular docking analysis and corroborative in-solution small-angle X-ray scattering data for titration of RBP3 with relevant ligands, that also give insights on RBP3 conformational adaptability.…”
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