Arterial hypertension and stiffness in women of different age groups and reproductive status by O. S. Ivanova, E. Y. Maychuk, I. V. Voevodina, I. A. Makarova, E. V. Akatova, A. I. Zavyalova, O. P. Nikolin

“…Correlation analysis revealed the most significant correlations between  the presence  of arterial hypertension (R=0,45-0,71;   p<<0,01)  with central aortic pressure, double product index and average daily aortic pulse wave velocity  in the aorta (PWVao),  regardless  of the state reproductive  function. …”
Get full text

Medical students’ perception of a unique humanistic mentoring program in a religious university: a convergent parallel mixed methods study by Tsung-Ying Chen, Wen-Lin Lo, Li-Chuan Kuo

“…Results Regarding the functional roles of three focused themes both quantitative and qualitative data revealed that participants viewed the program positively. …”
Get full text

Reliability of clinical impressions and optimal genetic diagnostic strategies of heritable connective tissue disorders with ocular involvement in a large Chinese cohort by Qin-Meng Shu, Yu-Qiao Ju, Yuan Zong, Ting Zhang, Xin Huang, Feng-juan Gao, Qing Chang

“…Pathogenicity of identified variants was assessed through conservation analysis and the functional impact, which was predicted using three-dimensional protein structure modeling. …”
Get full text

ASSESSMENT OF SEROUS LYMPH HATCHES IN PERITONEAL CARCINOMATOSIS (DIAPHRAGMATIC PERITONEUM) BY SCANNING ELECTRON MICROSCOPY by Sh. Kh. Gantsev, S. V. Solomenny, K. Sh. Gantsev, Sh. R. Kzyrgalin, R. S. Minigazimov, M. V. Loginova

“…Shown the similar results of studies of Japanese scientists, but selected the differences in the mechanisms of this process, in particular in the direction of movement of cancer cells. From data analysis results of quantitative and anatomical evaluation of serous lymph hatches diaphragmatic peritoneum we selected their functional classes. …”
Get full text

INFORMATION SECURITY IN MOBILE MODULAR MEASURING SYSTEMS by A. N. Tkhishev, P. S. Gorshkov, A. P. Golovkin

“…When carrying out their functions, it should be implemented a proper information control of the mobile modular measurement systems to ensure their protection from the risk of data leakage, modification or loss, i.e. to ensure a certain level of information security. …”
Get full text

The cognitive critical brain: Modulation of criticality in perception-related cortical regions by Xingyu Liu, Xiaotian Fei, Jia Liu

“…Specifically, we simulated 2D-Ising models in silico using structural MRI data and empirically estimated the system's state in vivo using functional MRI data. …”
Get full text

Application of Concentration-Area fractal modeling and artificial neural network to identify Cu, Zn±Pb geochemical anomalies in Hashtjin area, NW of Iran by Ali Imamalipour, Hamed Ebrahimi, Amir reza Abdollahpur

“…Discussion An autoencoder is a type of artificial neural network used for learning efficient encoding of unlabeled data (unsupervised learning). Autoencoder consists of two functions: an encoder function that encodes the input data into a lower-dimensional hidden layer and a decoder function that reconstructs the encoded input data. …”
Get full text

Systematic exploration of the molecular characteristics of CD8+ T cells to predict the response to immunotherapy and the prognosis of patients with colon adenocarcinoma by Xin Shen, Lifeng Shang, Junwei Han, Yi Zhang, Wenkai Niu, Haiwang Liu, Hai Shi

“…We developed a CD8+ T-cell score (CD8S) to quantify the population of CD8+ T cells in each COAD patient. A thorough analysis of multilevel data was conducted to evaluate overall survival (OS), biological functions, immunological profiles, drug sensitivity, and responses to immunotherapy between the two groups defined by CD8S. …”
Get full text

Multi-Objective Optimization of Urban Air Transportation Networks Under Social Considerations by Nikolas Hohmann, Sebastian Brulin, Jurgen Adamy, Markus Olhofer

“…Using geospatial data from Frankfurt, Germany, we conducted different experiments including and excluding the social objective function under a varying input set of pre-optimized paths. …”
Get full text

Effects of intermittent theta burst stimulation (iTBS) on appetite change and body weight in inpatients with schizophrenia in China: study protocol for a randomised controlled tria... by Jun Yang, Jing Huang, Jin Yang, Yue Qin, Renrong Wu, Jieyu Liu, Baoyan Xu, Haiyu Chen, Tianxiang Zou, Ziwei Teng, Tengteng Zhang, Yuhan Su, Zaiwen Dong, Chong Yang

“…MRI examination will be conducted to detect brain structure, perfusion and functional connectivity. Data analysis will be conducted in a modified intention-to-treat population. …”
Get full text

Прийоми реновації замкових комплексів та їх пристосування під сучасне використання на прикладі замку Свірж... by Sergiy Buravchenko, Oleksandr Pivovarov, Oleksandr Khlyupin, Iryna Shashkova

“…The modern use of castles is especially problematic due to the complexity of their functional adaptation. The experience of Europe shows that the solution to this problem is to define new functions to adapt architectural monuments to modern needs. …”
Get full text

Proteomic Characterization of Liver Cancer Cells Treated with Clinical Targeted Drugs for Hepatocellular Carcinoma by Hezhou Long, Jiafu Zhou, Changxia Zhou, Shuyu Xie, Jingling Wang, Minjia Tan, Junyu Xu

“…These sites were associated with poor prognosis and elevated functional scores. <b>Conclusions</b>: In summary, this study conducted an in-depth analysis of the molecular alterations in proteins and phosphorylation modifications induced by clinical HCC-targeted drugs, predicting drug combination strategies and therapeutic targets.…”
Get full text

PHYSICOCHEMICAL, ANTIOXIDANT ACTIVITY, ANTIBACTERIAL ACTIVITY, AND MELISSOPALYNOLOGY STUDY OF FENNEL, ANISE, AND CORIANDER HONEY by HEBATTALLAH EL SAYEH, WAEL MARZOUK, MOHAMED Abd El Dayem, OMNIA HASAN, AHMED KAMEL

“…In comparison, no ‌significant differences were recorded in total flavonoid content or antioxidant activity among the ‌three types of honey and flavonoid showed a highly significant positive correlation with ‌antioxidant activity, in addition, the data of antibacterial were generally similar in the three types ‌of honey under study, melissopalynology analysis showed that there&rsquo;s a slight difference in the ‌shape of fennel, anise, coriander pollen grain. …”
Get full text

A coagulation-related long non-coding RNA signature to predict prognosis and immune features of breast cancer by Yetao Han, Mengsi Hu, Yanzhong Wang, Shoufang Xu, Feiyu Jiang, Yingjian Wang, Zhiwei Liu

“…Long non-coding RNAs (lncRNAs) and coagulation-related genes (CRGs) are increasingly recognized for their roles in prognosis and immune modulation. Using transcriptomic data from 1,045 BC patients in TCGA, we identified CRG-associated lncRNAs via coexpression analysis (Pearson |R|> 0.4, p < 0.001) and constructed a prognostic model through univariate Cox analysis, LASSO regression with tenfold cross-validation (λ = 0.05), and multivariate Cox analysis. …”
Get full text

POLYMORPHIC VARIANTS OF GENES CODING SYMPATHOADRENAL SYSTEM INFLUENCE ON PHENOTYPE OF PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY by S. M. Komissarova, S. S. Nyazova, N. N. Chakova, O. V. Krasko

“…To reveal the associations of polymorphic genes variants coding the proteins of sympathoadrenal system (ADRB1 and ADRB2) with clinical phenotype of the disease including age and gender of patients with HCMP.Material and methods. The analysis of clinical-demographic and instrumental data of 275 patients with the diagnosis of HCMP (97 women and 178 men, age 17 to 70 y.o., median age 51 y. and 44 y., resp.) was done. …”
Get full text

Acute Myeloid Leukemia Genome Characterization Study and Subtype Classification Employing Feature Selection and Bayesian Networks by Zhenzhen Li, Jingwen Li, Sifan Li, Yangyang Wang, Jihan Wang

“…<b>Conclusions:</b> This study demonstrated the application of machine learning in genomic data analysis for identifying gene subsets relevant to AML diagnosis and classification, which could aid in improving the understanding of the molecular landscape of AML. …”
Get full text

STRATEGIC GOALS AND QUALITATIVE PROGRESS INDICATORS OF THE PROCESS OF NEO-INDUSTRIALISATION OF THE MANUFACTURING INDUSTRY IN UKRAINE by Olha Ilyash, Nataliia Semenchenko, Andrii Sachenko

“…The proposed approach is derived from a combination of economic data analysis, expert opinion and forecasting. Purpose. …”
Get full text

TRIM29 alleviates intervertebral disc degeneration through the PI3K/AKT/mTOR pathway by Qinghua Yang, Junfei Feng, Hongyuan Xu, Tao Kang, Qingjun Wei, Hua Jiang

“…Integrated analysis of RNA sequencing data, coupled with validation through polymerase chain reaction (PCR), western blot analysis, and immunohistochemistry in both clinical samples and IDD animal models, revealed a significant correlation between tripartite motif containing 29 (TRIM29) expression and IDD progression. …”
Get full text

Features of the Development Strategy Customer Relationship Management by I. M. Gurova

“…Functional, strategic and economic analysis, methods of formalization, forecasting and expert assessments are used to generalize information and solve assigned tasks. …”
Get full text

Comparing a Guideline-Based Mobile Health Intervention Versus Usual Care for High-Risk Adolescents With Asthma: Protocol of a Randomized Controlled Trial by Tamara T Perry, Jessica H Turner, Ariel Berlinski, Larry A Simmons, Rita H Brown, Kaymon Neal, Sarah A Marshall, Xing He, Simon Chung, Andrew Brown, Horace J Spencer 3rd, Jiang Bian

“…Full data analysis began in December 2024. …”
Get full text