Evolution of melanopsin photoreceptors: discovery and characterization of a new melanopsin in nonmammalian vertebrates. by James Bellingham, Shyam S Chaurasia, Zara Melyan, Cuimei Liu, Morven A Cameron, Emma E Tarttelin, P Michael Iuvone, Mark W Hankins, Gianluca Tosini, Robert J Lucas

“…Thus, our findings show for the first time that nonmammalian vertebrates retain two quite separate melanopsin genes, while mammals have just one. These data raise important questions regarding the functional differences between Opn4x and Opn4m pigments, the associated adaptive advantages for most vertebrate species in retaining both melanopsins, and the implications for mammalian biology of lacking Opn4x.…”
Get full text

Predictors of Complete Oral Intake in Patients With Stroke After Tracheostomy by Keita Tsuzuki, Naoki Mori, Yuki Hayami, Osamu Oshima, Hidekazu Sugawara, Tetsuya Tsuji

“…Sex, days from onset to admission, Functional Independence Measure motor and cognitive scores, body mass index, food intake level scale scores, and severe white matter hyperintensities were identified as potential predictors in the univariate analysis. …”
Get full text

The approaches to prevention and therapy of cardiovascular disorders in children with chronic bronchopulmonary pathology by G. O. Lezhenko, О. Ye. Pashkova

“…The ultrasound examination of the heart was performed using the Medison SonoAce 8000 ultrasound machine (USA) according to the standard procedure. The mathematical analysis and statistical processing of data were performed on a PC using the licensed software package of Statistic for Windows 10.RU using variation, correlation, regression and nonparametric methods of statistical analysis. …”
Get full text

An integrated coaching and mentoring entrepreneurial development framework to promote entrepreneurial self-efficacy by JP Cronje, Nicky Terblanche, Marietjie Theron-Wepener

“…This exploratory, qualitative study followed an inductive approach and employed Canonical Action Research (n=10) for data collection and analysis, leading to the development of the Integrated Coaching and Mentoring Entrepreneurial Development (ICMED) framework. …”

The polychotomy of NFT ownership: Motivational heterogeneity and underlying drivers by Lennart Ante

“…We investigate the motivations behind non-fungible token (NFT) ownership. Utilizing survey data from NFT owners, we identify four distinct groups based on their primary motivations: (1) Utilizers, who emphasize functional uses; (2) Socializers, motivated by community and networking; (3) Speculators, focused on profit potential; and (4) Aesthetes, who appreciate artistic and cultural aspects. …”
Get full text

KAJIAN INTEGRASI MATEMATIKA DAN ISLAM: RUMUS FUNGSI MATEMATIKA SEDEKAH DALAM AL-QURAN by Annisaul Qoyyimah, Moh. Atikurrahman, Maswar Maswar

“…The analysis was conducted through thematic interpretation and Islamic hermeneutics, followed by the conceptual formulation of reward multiplication using logical mathematical approaches through functional equations. …”
Get full text

The importance of environmental protection concept in European Central Bank law by Dimitrijević Marko B.

Get full text

The aggrephagy-related gene TUBA1B influences clinical outcomes in glioma patients by regulating the cell cycle by Zesheng Sun, Pengcheng Huang, Jialiang Lin, Guiping Jiang, Jian Chen, Qianqian Liu

“…TUBA1B, identified as a key gene through machine learning, was incorporated into a nomogram model using multivariate Cox regression. Its functions were validated through qRT-PCR, in vitro functional assays, and mouse xenograft models. …”
Get full text

Weight-loss associated DNA methylation patterns: targetable biomarkers and pathway insights by Longjin Zeng, Xu Chen, Longyao Zhang, Yaxian Qi, Lingchen Li, Chenrui Yin, Jianguo Sun

“…In summary, DNA methylation analysis not only identifies functional targets but also uncovers new gene-disease connections.…”
Get full text

Étude de l’activité de définition de noms chez des enfants de 9-11 ans issus de classes sociales contrastées by Thierry Chanselme, Marie-Christine Toczek, Damien Chabanal

“…The quantitative results of the study confirm those obtained from research on the relationship between socio-economic background and vocabulary breadth. The qualitative data from the analysis of the structure of 567 definitions, highlight moderate differences in the evolution towards the canonical form of the definition, according to social class. …”
Get full text

The impact of sensorial-motor sequels in the autonomy and independence of patients affected by Cerebrovascular Accidents (CVA) by Debora Sanchez Pedrolo, Carina Tárzia Kakihara, Margarida Maria de Almeida

“…Data were analyzed by the technique of thematic content analysis and lead to the emergence of four categories: immediate help and hospital treatment; the impact of sequels in the autonomy and independence; ways to face the limitations; and the role of physiotherapy in rehabilitation. …”
Get full text

Berberine Extends Lifespan in <i>C. elegans</i> Through Multi-Target Synergistic Antioxidant Effects by Yingshuo Bei, Ting Wang, Shuwen Guan

“…This study comprehensively investigated the lifespan-extending effects and molecular mechanisms of berberine in <i data-eusoft-scrollable-element="1">C. elegans</i> through integrated approaches including lifespan assays, locomotor activity analysis, oxidative stress challenges, and transcriptomic profiling. …”
Get full text

Enhancing Spatial Legibility through Building Layout Optimization: The Case of Erbil City Shopping Malls by Sally Ghanim, Faris Mustafa

“…The methodology employed a multi-method approach, combining qualitative (researcher's checklist) and quantitative (genetic algorithm, GA) methods in data processing and statistical analysis. Seven shopping malls in Erbil City with different spatial layout typologies served as case studies. …”
Get full text

Integration of scRNA-seq and bulk RNA-seq to reveal the association and potential molecular mechanisms of metabolic reprogramming regulated by lactylation and chemotherapy resistan... by Fang Ren, Xiaoao Pang, Feng Jin, Nannan Luan, Houhua Guo, Liancheng Zhu

“…This work seeks to clarify the mechanisms of resistance-related lactylation in OC, intending to offer novel theoretical foundations and therapy strategies for addressing chemoresistance.MethodsThrough the combined analysis of bulk RNA-seq and single-cell RNA-seq data, we initially found lactylation genes linked to chemoresistance. …”
Get full text

Metaphorical Space of Emotions in Russian: Structure and Cognitive Strategies of Modeling by L. G. Babenko, M. A. Romanova

“…A total of 2,091 lexemes with metaphorical meanings representing 19 fundamental emotive concepts were analyzed. The statistical analysis of the sample yielded data on the proportion of metaphorical meanings within grammatical, functionalsemantic, and denotative-ideographic classes of emotive vocabulary. …”
Get full text

Corrosion Inhibition Potential of Lagenaria breviflora (Christmas melon) Leaf Extract on Aluminium in Hydrochloric Acid Environment by C. A. Igboamalu, V. I. Chukwuike, A. O. James, O. Akaranta

“…The C-N bond stretching vibration was observed around 1243.19 cm-1, whereas the N-H bond vibration was noted at about 1592.20 cm-1. The C-I functional group was assigned the absorption bands seen at 523 cm-1. …”
Get full text

Human Moving Pattern Recognition toward Channel Number Reduction Based on Multipressure Sensor Network by Zhaoqin Peng, Chun Cao, Jiaoying Huang, Wentao Pan

“…Specifically, to improve the classification performance, PCA based dimensionality reduction and channel reduction based data fusion were introduced. Experimental outcomes verified the testing speed of the classification function which was improved without affecting the accuracy rate. …”
Get full text

Quality of life and associated factors among patients with cancer receiving chemotherapy at Dessie Comprehensive Specialized Hospital, North-East Ethiopia: a cross-sectional study by Ewunetie Mekashaw Bayked, Mekdes Getachew Yimam, Zemen Mengesha Yalew, Husien Nurahmed Toleha, Segenet Zewdie

“…The data was entered and cleaned using EpiData version 4.6 and exported to Statistical Package for Social Sciences (SPSS) version 27 for analysis. …”
Get full text

The role of Ikaros transcriptional factor in normal hematopoiesis and leukemogenesis: biological and clinical aspects by V. S. Vshivkoo, A. N. Meleshko

“…In hematopoietic cells Ikaros functions as a transcription factor, a key protein controlling T-, B-, NK-, and dendritic cells early differentiation. …”
Get full text

Short-term heavy drinking in a non-human primate model skews monocytes toward a hypo-inflammatory phenotype by Madison B. Blanton, Madison B. Blanton, Hami Hemati, Qi Qiao, Qi Qiao, Rupak Khadka, Gregory Hawk, Kathleen A. Grant, Ilhem Messaoudi

“…Monocytes were analyzed using a combination of flow cytometry, single-cell RNA-sequencing (scRNAseq), ELISAs, and Cleavage Under Targets and Tagmentation (CUT&amp;Tag).ResultsOur data show that 6 months of ethanol consumption rewires monocytes towards a hypo-inflammatory profile as evidenced by reduced cytokine production. scRNAseq analysis revealed distinct shifts in monocyte states/clusters with ethanol consumption and LPS stimulation in line with a shift to a hypo-inflammatory state. …”
Get full text